FGF10 maintains distal lung bud epithelium and excessive signaling leads to progenitor state arrest, distalization, and goblet cell metaplasia

BMC Developmental Biology

Volumn 8, Issue , 2008, Pages

  Nyeng, Pia ^a,b   Norgaard, Gitte A ^b   Kobberup, Sune ^b   Jensen, Jan ^a,b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF COLORADO DENVER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLUSTERIN; FIBROBLAST GROWTH FACTOR 10; SURFACTANT PROTEIN C; THYROID TRANSCRIPTION FACTOR 1; TRANSCRIPTION FACTOR PEA3; BETA CATENIN; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 4; CATNB PROTEIN, MOUSE; FGF10 PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; INSULIN PROMOTER FACTOR 1; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CONTROLLED STUDY; EMBRYO; FETUS LUNG; GOBLET CELL; LETHALITY; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM; LUNG DEVELOPMENT; METAPLASIA; MOUSE; NONHUMAN; PERINATAL DEATH; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STEM CELL; TRANSGENIC MOUSE; ANIMAL; BIOSYNTHESIS; CELL TRANSDIFFERENTIATION; EMBRYO (ANATOMY); EMBRYONIC STEM CELL; EPITHELIUM CELL; HYPERPLASIA; LUNG; LUNG ALVEOLUS; METABOLISM; MORPHOGENESIS; PATHOLOGY; PRENATAL DEVELOPMENT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE;

MUS MUSCULUS;

ANIMALS; BETA CATENIN; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELL TRANSDIFFERENTIATION; EMBRYO, MAMMALIAN; EMBRYONIC STEM CELLS; EPITHELIAL CELLS; FIBROBLAST GROWTH FACTOR 10; GOBLET CELLS; HOMEODOMAIN PROTEINS; HYPERPLASIA; LUNG; METAPLASIA; MICE; MICE, TRANSGENIC; MORPHOGENESIS; MUSCLE, SMOOTH; PULMONARY ALVEOLI; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS;

EID: 40349083964     PISSN: None     EISSN: 1471213X     Source Type: Journal    
DOI: 10.1186/1471-213X-8-2     Document Type: Article

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