Octaarginine-modified liposomes enhance cross-presentation by promoting the c-terminal trimming of antigen peptide

Molecular Pharmaceutics

Volumn 11, Issue 8, 2014, Pages 2787-2795

  Nakamura, Takashi ^a   Ono, Kouhei ^a   Suzuki, Yoshiteru ^a   Moriguchi, Rumiko ^a   Kogure, Kentaro ^b   Harashima, Hideyoshi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

antigen presentation; cell penetrating peptide; liposomes; proteasomes; trimming of antigen peptide

Indexed keywords

ARGININE DERIVATIVE; CELL PENETRATING PEPTIDE; LIPOSOME; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; OCTAARGININE; UNCLASSIFIED DRUG; ANTIGEN; ARGININE; CHLOROQUINE; HLA ANTIGEN CLASS 1; OLIGOPEPTIDE; OVALBUMIN; PROTEASOME;

ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; BONE MARROW CELL; CARBOXY TERMINAL SEQUENCE; CELL MATURATION; CELL MIGRATION; CROSS PRESENTATION; DENDRITIC CELL; ENDOCYTOSIS; ENDOSOME; INTERNALIZATION; MOUSE; NONHUMAN; PINOCYTOSIS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; ANIMAL; C57BL MOUSE; CD8+ T LYMPHOCYTE; CHEMISTRY; CONFOCAL MICROSCOPY; CYTOLOGY; FLOW CYTOMETRY; METABOLISM; PROTEIN TERTIARY STRUCTURE;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS; ARGININE; BONE MARROW CELLS; CD8-POSITIVE T-LYMPHOCYTES; CELL-PENETRATING PEPTIDES; CHLOROQUINE; CROSS-PRIMING; DENDRITIC CELLS; ENDOSOMES; FLOW CYTOMETRY; HISTOCOMPATIBILITY ANTIGENS CLASS I; LIPOSOMES; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; OLIGOPEPTIDES; OVALBUMIN; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STRUCTURE, TERTIARY;

EID: 84905472261     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp500147y     Document Type: Article

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