Trolox inhibits osteolytic bone metastasis of breast cancer through both PGE2-dependent and independent mechanisms

Biochemical Pharmacology

Volumn 91, Issue 1, 2014, Pages 51-60

  Lee, Jong Ho ^a   Kim, Bongjun ^a   Jin, Won Jong ^a   Kim, Jung Wook ^a   Kim, Hong Hee ^a   Ha, Hyunil ^b   Lee, Zang Hee ^a  

^a Seoul National University   (South Korea)

^b Korea Institute of Oriental Medicine (KIOM)   (South Korea)

Author keywords

Bone metastasis; Osteoclast; RANKL; Trolox

Indexed keywords

OSTEOCLAST DIFFERENTIATION FACTOR; PROSTAGLANDIN E2; TROLOX C;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE ATROPHY; BONE METASTASIS; BREAST CANCER; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; METASTASIS INHIBITION; MOUSE; NONHUMAN; OSTEOCLASTOGENESIS; OSTEOLYSIS; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; TUMOR VOLUME;

BONE METASTASIS; OSTEOCLAST; PGE(2); RANKL; TROLOX;

ANIMALS; ANTINEOPLASTIC AGENTS; BONE MARROW; BONE NEOPLASMS; BREAST NEOPLASMS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CHROMANS; COCULTURE TECHNIQUES; DINOPROSTONE; FEMALE; MICE; MICE, INBRED BALB C; OSTEOCLASTS; RANK LIGAND; TUMOR MICROENVIRONMENT;

EID: 84905458903     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2014.06.005     Document Type: Article

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