Mitomycin C-soybean phosphatidylcholine complex-loaded self-assembled PEG-Lipid-PLA hybrid nanoparticles for targeted drug delivery and dual-controlled drug release

Molecular Pharmaceutics

Volumn 11, Issue 8, 2014, Pages 2915-2927

  Li, Yang ^a   Wu, Hongjie ^a   Yang, Xiangrui ^a   Jia, Mengmeng ^a   Li, Yanxiu ^a   Huang, Yu ^a   Lin, Jinyan ^a   Wu, Shichao ^a   Hou, Zhenqing ^a  

^a XIAMEN UNIVERSITY   (China)

Author keywords

complex; drug delivery; mitomycin C; pH sensitive; self assembled hybrid NPs; tumor targeting

Indexed keywords

AMPHOPHILE; DRUG CARRIER; GLYCEROPHOSPHOLIPID; MACROGOL; MITOMYCIN; NANOPARTICLE; POLYLACTIC ACID; SOYBEAN PHOSPHATIDYLCHOLINE; UNCLASSIFIED DRUG; LACTIC ACID; LIGAND; MACROGOL DERIVATIVE; PHOSPHATIDYLCHOLINE; POLYMER; WATER;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; CANCER SIZE; CELL VIABILITY; CELLULAR DISTRIBUTION; CIRCULATION; CIRCULATION TIME; COMPLEX FORMATION; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG UPTAKE; ENCAPSULATION; ERYTHROCYTE; EX VIVO STUDY; HELA CELL LINE; HEMOLYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROPHILICITY; HYDROPHOBICITY; IN VITRO STUDY; MALE; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; ZETA POTENTIAL; ANIMAL; CANCER TRANSPLANTATION; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; MOUSE; PH; SOLUBILITY; SOYBEAN; SPRAGUE DAWLEY RAT; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CELL SURVIVAL; DRUG DELIVERY SYSTEMS; HELA CELLS; HEMOLYSIS; HUMANS; HYDROGEN-ION CONCENTRATION; LACTIC ACID; LIGANDS; MALE; MICE; MITOMYCIN; NANOPARTICLES; NEOPLASM TRANSPLANTATION; PARTICLE SIZE; PHOSPHATIDYLCHOLINES; POLYETHYLENE GLYCOLS; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; SOYBEANS; WATER;

EID: 84905453206     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp500254j     Document Type: Article

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