Anti-tumor activity of paclitaxel through dual-targeting carrier of cyclic RGD and transferrin conjugated hyperbranched copolymer nanoparticles

Biomaterials

Volumn 33, Issue 5, 2012, Pages 1627-1639

  Xu, Qing ^a   Liu, Yuexian ^a   Su, Shishuai ^a   Li, Wei ^b   Chen, Chunying ^a   Wu, Yan ^a  

^a NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY   (China)

^b INSTITUTE OF HIGH ENERGY PHYSICS   (China)

Author keywords

Controlled drug release; CRGDfK; Hyperbranched copolymer nanoparticle; Intrinsic fluorescence; Transferrin; Tumor targeting

Indexed keywords

CONTROLLED DRUG RELEASE; CRGDFK; HYPERBRANCHED COPOLYMERS; INTRINSIC FLUORESCENCE; TRANSFERRIN; TUMOR-TARGETING;

BIODEGRADABLE POLYMERS; CHEMOTHERAPY; COPOLYMERS; CYTOTOXICITY; DRUG DELIVERY; ENZYME INHIBITION; FLUORESCENCE; MOLECULAR BIOLOGY; NANOPARTICLES; ORGANIC COMPOUNDS; TUMORS;

ENDOTHELIAL CELLS;

AMPHOPHILE; ARGINYLGLYCYLASPARTIC ACID; BIOPOLYMER; COPOLYMER; CYCLOPEPTIDE; DIPALMITOYLPHOSPHATIDYLETHANOLAMINE; DRUG CARRIER; NANOPARTICLE; PACLITAXEL; POLY[(AMINE ESTER) CO (LACTIDE)]; POLYLACTIDE; TRANSFERRIN; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CARBON NUCLEAR MAGNETIC RESONANCE; CELL VIABILITY; CONTROLLED DRUG RELEASE; CYTOTOXICITY; DISPERSION; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG FORMULATION; DRUG RECEPTOR BINDING; DRUG TARGETING; ENDOCYTOSIS; FEMALE; HELA CELL; HUMAN; HUMAN CELL; IC 50; INFRARED SPECTROSCOPY; LIGHT SCATTERING; NANOENCAPSULATION; PARTICLE SIZE; PH; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; SUSTAINED DRUG RELEASE; SYNTHESIS; TRANSMISSION ELECTRON MICROSCOPY; UMBILICAL VEIN ENDOTHELIAL CELL; ZETA POTENTIAL;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL SURVIVAL; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; ENDOCYTOSIS; HELA CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INHIBITORY CONCENTRATION 50; INTRACELLULAR SPACE; LIGANDS; LIGHT; MAGNETIC RESONANCE SPECTROSCOPY; NANOPARTICLES; NEOPLASMS; PACLITAXEL; PEPTIDES, CYCLIC; POLYMERS; SCATTERING, RADIATION; SOLUTIONS; SPECTROMETRY, FLUORESCENCE; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SUBCELLULAR FRACTIONS; TIME FACTORS; TRANSFERRIN;

EID: 83355177979     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.11.012     Document Type: Article

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