Mechanistic insight into the enzymatic reduction of truncated hemoglobin N of Mycobacterium tuberculosis: Role of the CD loop and Pre-A motif in electron cycling

Journal of Biological Chemistry

Volumn 289, Issue 31, 2014, Pages 21573-21583

  Singh, Sandeep ^a   Thakur, Naveen ^a   Oliveira, Ana ^b   Petruk, Ariel A ^c   Hade, Mangesh Dattu ^a   Sethi, Deepti ^a   Bidon Chanal, Axel ^b   Martí, Marcelo A ^c   Datta, Himani ^a   Parkesh, Raman ^a   Estrin, Dario A ^c   Luque, F Javier ^b   Dikshit, Kanak L ^a  

^a INSTITUTE OF MICROBIAL TECHNOLOGY   (India)

^b UNIVERSITY OF BARCELONA   (Spain)

^c UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

DETOXIFICATION; ELECTRON TRANSITIONS; ENZYME ACTIVITY; ESCHERICHIA COLI; HEMOGLOBIN; NITRIC OXIDE;

DETOXIFICATION MECHANISM; ENZYMATIC REDUCTION; INTERMOLECULAR INTERACTIONS; MYCOBACTERIUM TUBERCULOSIS; PATHOGENIC MICROORGANISMS; SITE DIRECTED MUTAGENESIS; TRUNCATED HEMOGLOBINS; VITREOSCILLA HEMOGLOBIN;

REDUCTION;

FERREDOXIN; FLAVODOXIN; GLYCINE; HEME; HEMOGLOBIN N; HEMOGLOBIN VARIANT; IRON; MYOGLOBIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; TRUNCATED HEMOGLOBIN; UNCLASSIFIED DRUG; HEMOGLOBINS N; PRIMER DNA;

ARTICLE; CATALYSIS; CONTROLLED STUDY; ELECTRON TRANSPORT; ESCHERICHIA COLI; MOLECULAR DOCKING; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; VITREOSCILLA; CHEMISTRY; ELECTRON; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR DYNAMICS; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION; POLYMERASE CHAIN REACTION;

BASE SEQUENCE; DNA PRIMERS; ELECTRON TRANSPORT; ELECTRONS; HEMOGLOBINS, ABNORMAL; MOLECULAR DYNAMICS SIMULATION; MUTAGENESIS, SITE-DIRECTED; MYCOBACTERIUM TUBERCULOSIS; OXIDATION-REDUCTION; POLYMERASE CHAIN REACTION;

EID: 84905395528     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.578187     Document Type: Article

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