Mycobacterium tuberculosis hemoglobin N displays a protein tunnel suited for O2 diffusion to the heme

EMBO Journal

Volumn 20, Issue 15, 2001, Pages 3902-3909

  Milani, Mario ^a,b   Pesce, Alessandra ^a   Ouellet, Yannick ^c   Ascenzi, Paolo ^a,d   Guertin, Michel ^c   Bolognesi, Martino ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b G GASLINI INSTITUTE   (Italy)

^c UNIVERSITÉ LAVAL   (Canada)

^d ROMA TRE UNIVERSITY   (Italy)

Author keywords

Hemoprotein structure; Macrophage oxidative stress; Mycobacterium tuberculosis; Nitric oxide; Truncated hemoglobins

Indexed keywords

BACTERIAL PROTEIN; HEME; HEME DERIVATIVE; HEMOGLOBIN; LIGAND; NITRIC OXIDE;

ALPHA HELIX; ARTICLE; BACTERIAL INFECTION; DETOXIFICATION; HYDROGEN BOND; MACROPHAGE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OXIDATIVE STRESS; OXYGEN DIFFUSION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN STRUCTURE; STEREOCHEMISTRY;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HEME; HEMOGLOBINS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; OXYGEN; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY;

EID: 0035423114     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.15.3902     Document Type: Article

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