Role of PheE15 Gate in Ligand Entry and Nitric Oxide Detoxification Function of Mycobacterium tuberculosis Truncated Hemoglobin N

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Oliveira, Ana ^a   Singh, Sandeep ^b   Bidon Chanal, Axel ^a   Forti, Flavio ^a   Martí, Marcelo A ^c   Boechi, Leonardo ^c   Estrin, Dario A ^c   Dikshit, Kanak L ^b   Luque, F Javier ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b INSTITUTE OF MICROBIAL TECHNOLOGY   (India)

^c UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; DIOXYGENASE; HEME; ISOLEUCINE; NITRIC OXIDE DIOXYGENASE; OXYGEN; PHENYLALANINE; PHENYLALANINE 15; TRUNCATED HEMOGLOBIN; TRUNCATED HEMOGLOBIN N; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DETOXIFICATION; DOWN REGULATION; ENZYME ACTIVITY; LIGAND BINDING; MOLECULAR DYNAMICS; MUTANT; MUTATIONAL ANALYSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OXIDATION; OXYGEN AFFINITY; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS; WILD TYPE;

BACTERIAL PROTEINS; BINDING SITES; CARBON MONOXIDE; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; LIGANDS; MUTAGENESIS, SITE-DIRECTED; MYCOBACTERIUM TUBERCULOSIS; NITRIC OXIDE; OXYGEN; PHENYLALANINE; PROTEIN STRUCTURE, TERTIARY; TRUNCATED HEMOGLOBINS;

MYCOBACTERIUM TUBERCULOSIS;

EID: 84869068674     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0049291     Document Type: Article

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