Structural basis for polyspecificity in the POT family of proton-coupled oligopeptide transporters

EMBO Reports

Volumn 15, Issue 8, 2014, Pages 886-893

  Lyons, Joseph A ^a,c   Parker, Joanne L ^b,c   Solcan, Nicolae ^b   Brinth, Alette ^a   Li, Dianfan ^a   Shah, Syed Ta ^a   Caffrey, Martin ^a   Newstead, Simon ^b  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c AARHUS UNIVERSITY   (Denmark)

Author keywords

crystallography; major facilitator superfamily; membrane protein; peptide binding site; POT PTR family

Indexed keywords

ALAFOSFALIN; CARRIER PROTEIN; COTRANSPORTER; DIPEPTIDE; PEPTIDE TRANSPORTER 1; PROTON COUPLED PEPTIDE TRANSPORTER; TRIPEPTIDE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; OLIGOPEPTIDE;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME SPECIFICITY; HINGE REGION; HYDROGEN BOND; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; PROTEIN TRANSPORT; STATIC ELECTRICITY; CHEMICAL PHENOMENA; CHEMICAL STRUCTURE; CHEMISTRY; PROTEIN SECONDARY STRUCTURE; STREPTOCOCCUS THERMOPHILUS; X RAY CRYSTALLOGRAPHY;

BACTERIAL PROTEINS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DIPEPTIDES; HYDROGEN BONDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MODELS, MOLECULAR; OLIGOPEPTIDES; PROTEIN STRUCTURE, SECONDARY; STREPTOCOCCUS THERMOPHILUS; SUBSTRATE SPECIFICITY; SYMPORTERS;

EID: 84905394556     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201338403     Document Type: Article

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