-
1
-
-
0036645414
-
Molecular biology of the androgen receptor
-
Gelmann, E. P. (2002) Molecular biology of the androgen receptor. J. Clin. Oncol. 20, 3001-3015
-
(2002)
J. Clin. Oncol.
, vol.20
, pp. 3001-3015
-
-
Gelmann, E.P.1
-
2
-
-
84857360697
-
Post-translational modification of the androgen receptor
-
Gioeli, D., and Paschal, B. M. (2012) Post-translational modification of the androgen receptor. Mol. Cell. Endocrinol. 352, 70-78
-
(2012)
Mol. Cell. Endocrinol.
, vol.352
, pp. 70-78
-
-
Gioeli, D.1
Paschal, B.M.2
-
3
-
-
84858041599
-
Androgen receptor signaling in prostate cancer development and progression
-
Lonergan, P. E., and Tindall, D. J. (2011) Androgen receptor signaling in prostate cancer development and progression. J. Carcinog. 10, 20
-
(2011)
J. Carcinog.
, vol.10
, pp. 20
-
-
Lonergan, P.E.1
Tindall, D.J.2
-
4
-
-
84879127816
-
Targeting alternative sites on the androgen receptor to treat castration-resistant prostate cancer
-
Lallous, N., Dalal, K., Cherkasov, A., and Rennie, P. S. (2013) Targeting alternative sites on the androgen receptor to treat castration-resistant prostate cancer. Int. J. Mol. Sci. 14, 12496-12519
-
(2013)
Int. J. Mol. Sci.
, vol.14
, pp. 12496-12519
-
-
Lallous, N.1
Dalal, K.2
Cherkasov, A.3
Rennie, P.S.4
-
5
-
-
2342558431
-
Androgen receptor in prostate cancer
-
Heinlein, C. A., and Chang, C. (2004) Androgen receptor in prostate cancer. Endocr. Rev. 25, 276-308
-
(2004)
Endocr. Rev.
, vol.25
, pp. 276-308
-
-
Heinlein, C.A.1
Chang, C.2
-
6
-
-
84864622006
-
Evidence for DNAbinding domain-ligand-binding domain communications in the androgen receptor
-
Helsen, C., Dubois, V., Verfaillie, A., Young, J., Trekels, M., Vancraenenbroeck, R., De Maeyer, M., and Claessens, F. (2012) Evidence for DNAbinding domain-ligand-binding domain communications in the androgen receptor. Mol. Cell. Biol. 32, 3033-3043
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 3033-3043
-
-
Helsen, C.1
Dubois, V.2
Verfaillie, A.3
Young, J.4
Trekels, M.5
Vancraenenbroeck, R.6
De Maeyer, M.7
Claessens, F.8
-
7
-
-
0041857786
-
The androgen receptor: Structure, mutations, and antiandrogens
-
Hirawat, S., Budman, D. R., and Kreis, W. (2003) The androgen receptor: structure, mutations, and antiandrogens. Cancer Invest. 21, 400-417
-
(2003)
Cancer Invest.
, vol.21
, pp. 400-417
-
-
Hirawat, S.1
Budman, D.R.2
Kreis, W.3
-
8
-
-
0033178805
-
Differential DNA binding by the androgen and glucocorticoid receptors involves the second Zn-finger and a C-terminal extension of the DNA-binding domains
-
Schoenmakers, E., Alen, P., Verrijdt, G., Peeters, B., Verhoeven, G., Rombauts, W., and Claessens, F. (1999) Differential DNA binding by the androgen and glucocorticoid receptors involves the second Zn-finger and a C-terminal extension of the DNA-binding domains. Biochem. J. 341, 515-521
-
(1999)
Biochem. J.
, vol.341
, pp. 515-521
-
-
Schoenmakers, E.1
Alen, P.2
Verrijdt, G.3
Peeters, B.4
Verhoeven, G.5
Rombauts, W.6
Claessens, F.7
-
9
-
-
84888364915
-
Maintenance of androgen receptor inactivation by S-nitrosylation
-
Qin, Y., Dey, A., Purayil, H. T., and Daaka, Y. (2013) Maintenance of androgen receptor inactivation by S-nitrosylation. Cancer Res. 73, 6690-6699
-
(2013)
Cancer Res.
, vol.73
, pp. 6690-6699
-
-
Qin, Y.1
Dey, A.2
Purayil, H.T.3
Daaka, Y.4
-
10
-
-
84880729344
-
Posttranslational modification of the androgen receptor in prostate cancer
-
van der Steen, T., Tindall, D. J., and Huang, H. (2013) Posttranslational modification of the androgen receptor in prostate cancer. Int. J. Mol. Sci. 14, 14833-14859
-
(2013)
Int. J. Mol. Sci.
, vol.14
, pp. 14833-14859
-
-
Van Der Steen, T.1
Tindall, D.J.2
Huang, H.3
-
11
-
-
0033323810
-
A C619Y mutation in the human androgen receptor causes inactivation and mislocalization of the receptor with concomitant sequestration of SRC-1 (steroid receptor coactivator 1)
-
Nazareth, L. V., Stenoien, D. L., Bingman, W. E., 3rd, James, A. J., Wu, C., Zhang, Y., Edwards, D. P., Mancini, M., Marcelli, M., Lamb, D. J., and Weigel, N. L. (1999) A C619Y mutation in the human androgen receptor causes inactivation and mislocalization of the receptor with concomitant sequestration of SRC-1 (steroid receptor coactivator 1). Mol. Endocrinol. 13, 2065-2075
-
(1999)
Mol. Endocrinol.
, vol.13
, pp. 2065-2075
-
-
Nazareth, L.V.1
Stenoien, D.L.2
Bingman III, W.E.3
James, A.J.4
Wu, C.5
Zhang, Y.6
Edwards, D.P.7
Mancini, M.8
Marcelli, M.9
Lamb, D.J.10
Weigel, N.L.11
-
13
-
-
67651165192
-
D, L-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells
-
Kim, S. H., and Singh, S. V. (2009) D, L-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells. Mol. Cancer Ther. 8, 1946-1954
-
(2009)
Mol. Cancer Ther.
, vol.8
, pp. 1946-1954
-
-
Kim, S.H.1
Singh, S.V.2
-
15
-
-
79959312178
-
The slow-releasing hydrogen sulfide donor, GYY4137, exhibits novel anti-cancer effects in vitro and in vivo
-
Lee, Z. W., Zhou, J., Chen, C. S., Zhao, Y., Tan, C. H., Li, L., Moore, P. K., and Deng, L. W. (2011) The slow-releasing hydrogen sulfide donor, GYY4137, exhibits novel anti-cancer effects in vitro and in vivo. PLoS One 6, e21077
-
(2011)
PLoS One
, vol.6
-
-
Lee, Z.W.1
Zhou, J.2
Chen, C.S.3
Zhao, Y.4
Tan, C.H.5
Li, L.6
Moore, P.K.7
Deng, L.W.8
-
17
-
-
84863024767
-
Characterization of hydrogen sulfide and its synthases, cystathionine β-synthase and cystathionine γ-lyase, in human prostatic tissue and cells
-
Guo, H., Gai, J. W., Wang, Y., Jin, H. F., Du, J. B., and Jin, J. (2012) Characterization of hydrogen sulfide and its synthases, cystathionine β-synthase and cystathionine γ-lyase, in human prostatic tissue and cells. Urology 79, 483e1-483e5
-
(2012)
Urology
, vol.79
-
-
Guo, H.1
Gai, J.W.2
Wang, Y.3
Jin, H.F.4
Du, J.B.5
Jin, J.6
-
18
-
-
55749095720
-
Human tumor growth in nude mice is associated with decreased plasma cysteine and homocysteine
-
Al-Awadi, F., Yang, M., Tan, Y., Han, Q., Li, S., and Hoffman, R. M. (2008) Human tumor growth in nude mice is associated with decreased plasma cysteine and homocysteine. Anticancer Res. 28, 2541-2544
-
(2008)
Anticancer Res.
, vol.28
, pp. 2541-2544
-
-
Al-Awadi, F.1
Yang, M.2
Tan, Y.3
Han, Q.4
Li, S.5
Hoffman, R.M.6
-
19
-
-
77749271091
-
Hydrogen sulfide as a gasotransmitter
-
Gadalla, M. M., and Snyder, S. H. (2010) Hydrogen sulfide as a gasotransmitter. J. Neurochem. 113, 14-26
-
(2010)
J. Neurochem.
, vol.113
, pp. 14-26
-
-
Gadalla, M.M.1
Snyder, S.H.2
-
20
-
-
74949103637
-
2S signals through protein S-sulfhydration
-
2S signals through protein S-sulfhydration. Sci. Signal 2, ra72
-
(2009)
Sci. Signal
, vol.2
-
-
Mustafa, A.K.1
Gadalla, M.M.2
Sen, N.3
Kim, S.4
Mu, W.5
Gazi, S.K.6
Barrow, R.K.7
Yang, G.8
Wang, R.9
Snyder, S.H.10
-
21
-
-
54949084607
-
2S as a physiologic vasorelaxant: Hypertension in mice with deletion of cystathionine γ-lyase
-
2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine γ-lyase. Science 322, 587-590
-
(2008)
Science
, vol.322
, pp. 587-590
-
-
Yang, G.1
Wu, L.2
Jiang, B.3
Yang, W.4
Qi, J.5
Cao, K.6
Meng, Q.7
Mustafa, A.K.8
Mu, W.9
Zhang, S.10
Snyder, S.H.11
Wang, R.12
-
22
-
-
84868507799
-
Increased expression of activated endothelial nitric oxide synthase contributes to antiandrogen resistance in prostate cancer cells by suppressing androgen receptor transactivation
-
Yu, S., Jia, L., Zhang, Y., Wu, D., Xu, Z., Ng, C. F., To, K. K., Huang, Y., and Chan, F. L. (2013) Increased expression of activated endothelial nitric oxide synthase contributes to antiandrogen resistance in prostate cancer cells by suppressing androgen receptor transactivation. Cancer Lett. 328, 83-94
-
(2013)
Cancer Lett.
, vol.328
, pp. 83-94
-
-
Yu, S.1
Jia, L.2
Zhang, Y.3
Wu, D.4
Xu, Z.5
Ng, C.F.6
To, K.K.7
Huang, Y.8
Chan, F.L.9
-
23
-
-
84876135908
-
Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2
-
Yang, G., Zhao, K., Ju, Y., Mani, S., Cao, Q., Puukila, S., Khaper, N., Wu, L., and Wang, R. (2013) Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2. Antioxid. Redox Signal 18, 1906-1919
-
(2013)
Antioxid. Redox Signal
, vol.18
, pp. 1906-1919
-
-
Yang, G.1
Zhao, K.2
Ju, Y.3
Mani, S.4
Cao, Q.5
Puukila, S.6
Khaper, N.7
Wu, L.8
Wang, R.9
-
24
-
-
84888343067
-
Androgen regulation of the TMPRSS2 gene and the effect of a SNP in an androgen response element
-
Clinckemalie, L., Spans, L., Dubois, V., Laurent, M., Helsen, C., Joniau, S., and Claessens, F. (2013) Androgen regulation of the TMPRSS2 gene and the effect of a SNP in an androgen response element. Mol. Endocrinol. 27, 2028-2040
-
(2013)
Mol. Endocrinol.
, vol.27
, pp. 2028-2040
-
-
Clinckemalie, L.1
Spans, L.2
Dubois, V.3
Laurent, M.4
Helsen, C.5
Joniau, S.6
Claessens, F.7
-
25
-
-
79960687138
-
Specificity protein-1 as a critical regulator of human cystathionine γ-lyase expression during smooth muscle cell differentiation
-
Yang, G., Pei, Y., Teng, H., Cao, Q., and Wang, R. (2011) Specificity protein-1 as a critical regulator of human cystathionine γ-lyase expression during smooth muscle cell differentiation. J. Biol. Chem. 286, 26450-26460
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 26450-26460
-
-
Yang, G.1
Pei, Y.2
Teng, H.3
Cao, Q.4
Wang, R.5
-
26
-
-
0042161800
-
Induction of cre recombinase activity using modified androgen receptor ligand binding domains: A sensitive assay for ligand-receptor interactions
-
Kaczmarczyk, S. J., and Green, J. E. (2003) Induction of cre recombinase activity using modified androgen receptor ligand binding domains: a sensitive assay for ligand-receptor interactions. Nucleic Acids Res. 31, e86
-
(2003)
Nucleic Acids Res.
, vol.31
-
-
Kaczmarczyk, S.J.1
Green, J.E.2
-
27
-
-
0032945938
-
Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone
-
Stenoien, D. L., Cummings, C. J., Adams, H. P., Mancini, M. G., Patel, K., DeMartino, G. N., Marcelli, M., Weigel, N. L., and Mancini, M. A. (1999) Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone. Hum. Mol. Genet. 8, 731-741
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 731-741
-
-
Stenoien, D.L.1
Cummings, C.J.2
Adams, H.P.3
Mancini, M.G.4
Patel, K.5
DeMartino, G.N.6
Marcelli, M.7
Weigel, N.L.8
Mancini, M.A.9
-
28
-
-
0029125762
-
Structural analysis of porcine brain nitric oxide synthase reveals a role for tetrahydrobiopterin and L-arginine in the formation of an SDSresistant dimer
-
Klatt, P., Schmidt, K., Lehner, D., Glatter, O., Bächinger, H. P., and Mayer, B. (1995) Structural analysis of porcine brain nitric oxide synthase reveals a role for tetrahydrobiopterin and L-arginine in the formation of an SDSresistant dimer. EMBO J. 14, 3687-3695
-
(1995)
EMBO J.
, vol.14
, pp. 3687-3695
-
-
Klatt, P.1
Schmidt, K.2
Lehner, D.3
Glatter, O.4
Bächinger, H.P.5
Mayer, B.6
-
29
-
-
33645836479
-
2S on human aorta smooth muscle cells
-
2S on human aorta smooth muscle cells. FASEB J. 20, 553-555
-
(2006)
FASEB J.
, vol.20
, pp. 553-555
-
-
Yang, G.1
Wu, L.2
Wang, R.3
-
30
-
-
80052435577
-
Pathogenic role of cystathionine γ-lyase and hydrogen sulfide in type 1 diabetes mellitus
-
Yang, G., Tang, G., Zhang, L., Wu, L., and Wang, R. (2011) Pathogenic role of cystathionine γ-lyase and hydrogen sulfide in type 1 diabetes mellitus. Am. J. Pathol. 179, 869-879
-
(2011)
Am. J. Pathol.
, vol.179
, pp. 869-879
-
-
Yang, G.1
Tang, G.2
Zhang, L.3
Wu, L.4
Wang, R.5
-
31
-
-
84863528233
-
2S generation by CBS, CSE, and 3MST gene therapy improves ex vivo renovascular relaxation in hyperhomocysteinemia
-
2S generation by CBS, CSE, and 3MST gene therapy improves ex vivo renovascular relaxation in hyperhomocysteinemia. Am. J. Physiol. Cell Physiol. 303, C41-C51
-
(2012)
Am. J. Physiol. Cell Physiol.
, vol.303
-
-
Sen, U.1
Sathnur, P.B.2
Kundu, S.3
Givvimani, S.4
Coley, D.M.5
Mishra, P.K.6
Qipshidze, N.7
Tyagi, N.8
Metreveli, N.9
Tyagi, S.C.10
-
32
-
-
84899484919
-
Annual Report to the Nation on the status of cancer, 1975-2010, featuring prevalence of comorbidity and impact on survival among persons with lung, colorectal, breast, or prostate cancer
-
Edwards, B. K., Noone, A. M., Mariotto, A. B., Simard, E. P., Boscoe, F. P., Henley, S. J., Jemal, A., Cho, H., Anderson, R. N., Kohler, B. A., Eheman, C. R., and Ward, E. M. (2014) Annual Report to the Nation on the status of cancer, 1975-2010, featuring prevalence of comorbidity and impact on survival among persons with lung, colorectal, breast, or prostate cancer. Cancer 120, 1290-1314
-
(2014)
Cancer
, vol.120
, pp. 1290-1314
-
-
Edwards, B.K.1
Noone, A.M.2
Mariotto, A.B.3
Simard, E.P.4
Boscoe, F.P.5
Henley, S.J.6
Jemal, A.7
Cho, H.8
Anderson, R.N.9
Kohler, B.A.10
Eheman, C.R.11
Ward, E.M.12
-
33
-
-
33847392500
-
Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression
-
Wissmann, M., Yin, N., Müller, J. M., Greschik, H., Fodor, B. D., Jenuwein, T., Vogler, C., Schneider, R., Günther, T., Buettner, R., Metzger, E., and Schüle, R. (2007) Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression. Nat. Cell Biol. 9, 347-353
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 347-353
-
-
Wissmann, M.1
Yin, N.2
Müller, J.M.3
Greschik, H.4
Fodor, B.D.5
Jenuwein, T.6
Vogler, C.7
Schneider, R.8
Günther, T.9
Buettner, R.10
Metzger, E.11
Schüle, R.12
-
35
-
-
33645690200
-
Mechanisms underlying the development of androgen-independent prostate cancer
-
Pienta, K. J., and Bradley, D. (2006) Mechanisms underlying the development of androgen-independent prostate cancer. Clin. Cancer Res. 12, 1665-1671
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 1665-1671
-
-
Pienta, K.J.1
Bradley, D.2
-
36
-
-
84860117196
-
Physiological implications of hydrogen sulfide: A whiff exploration that blossomed
-
Wang, R. (2012) Physiological implications of hydrogen sulfide: a whiff exploration that blossomed. Physiol. Rev. 92, 791-896
-
(2012)
Physiol. Rev.
, vol.92
, pp. 791-896
-
-
Wang, R.1
-
37
-
-
0346690367
-
Myc confers androgen-independent prostate cancer cell growth
-
Bernard, D., Pourtier-Manzanedo, A., Gil, J., Beach, D. H. (2003) Myc confers androgen-independent prostate cancer cell growth. J. Clin. Invest. 112, 1724-1731
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1724-1731
-
-
Bernard, D.1
Pourtier-Manzanedo, A.2
Gil, J.3
Beach, D.H.4
-
38
-
-
84863938860
-
Elevation of c-FLIP in castrate-resistant prostate cancer antagonizes therapeutic response to androgen receptor-targeted therapy
-
McCourt, C., Maxwell, P., Mazzucchelli, R., Montironi, R., Scarpelli, M., Salto-Tellez, M., O'Sullivan, J. M., Longley, D. B., and Waugh, D. J. (2012) Elevation of c-FLIP in castrate-resistant prostate cancer antagonizes therapeutic response to androgen receptor-targeted therapy. Clin. Cancer Res. 18, 3822-3833
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 3822-3833
-
-
McCourt, C.1
Maxwell, P.2
Mazzucchelli, R.3
Montironi, R.4
Scarpelli, M.5
Salto-Tellez, M.6
O'Sullivan, J.M.7
Longley, D.B.8
Waugh, D.J.9
-
39
-
-
1842637389
-
Structural basis of androgen receptor binding to selective androgen response elements
-
Shaffer, P. L., Jivan, A., Dollins, D. E., Claessens, F., and Gewirth, D. T. (2004) Structural basis of androgen receptor binding to selective androgen response elements. Proc. Natl. Acad. Sci. U. S. A. 101, 4758-4763
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 4758-4763
-
-
Shaffer, P.L.1
Jivan, A.2
Dollins, D.E.3
Claessens, F.4
Gewirth, D.T.5
-
40
-
-
55049086227
-
The contribution of different androgen receptor domains to receptor dimerization and signaling
-
Centenera, M. M., Harris, J. M., Tilley, W. D., and Butler, L. M. (2008) The contribution of different androgen receptor domains to receptor dimerization and signaling. Mol. Endocrinol. 22, 2373-2382
-
(2008)
Mol. Endocrinol.
, vol.22
, pp. 2373-2382
-
-
Centenera, M.M.1
Harris, J.M.2
Tilley, W.D.3
Butler, L.M.4
-
41
-
-
84863111874
-
Stepwise androgen receptor dimerization
-
van Royen, M. E., van Cappellen, W. A., de Vos, C., Houtsmuller, A. B., and Trapman, J. (2012) Stepwise androgen receptor dimerization. J. Cell Sci. 125, 1970-1979
-
(2012)
J. Cell Sci.
, vol.125
, pp. 1970-1979
-
-
Van Royen, M.E.1
Van Cappellen, W.A.2
De Vos, C.3
Houtsmuller, A.B.4
Trapman, J.5
|