Intra-colonic administration of a polymer-bound NIRF probe for improved colorectal cancer detection during colonoscopy

Journal of Controlled Release

Volumn 192, Issue , 2014, Pages 182-191

  Kogan Zviagin, Inga ^a   Shamay, Yosi ^a   Nissan, Aviram ^b   Sella Tavor, Osnat ^c   Golan, Moran ^a   David, Ayelet ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^c Given Imaging Ltd   (Israel)

Author keywords

Colorectal cancer; HPMA copolymer; Imaging probe; Intracolonic administration; Near infrared fluorescence

Indexed keywords

DIAGNOSIS; FLUORESCENCE; HISTOLOGY; INFRARED DEVICES; MAMMALS; MONOCLONAL ANTIBODIES; NANOPARTICLES; PEPTIDES; PROBES; TUMORS;

COLORECTAL CANCER; COLORECTAL CANCERS (CRC); EPITHELIAL CANCER CELLS; FLUORESCEIN ISOTHIOCYANATE; HPMA COPOLYMERS; IMAGING PROBE; NEAR-INFRARED FLUORESCENCE; PARENTERAL ADMINISTRATION; COLONOSCOPY;

DISEASES;

EPPT1 PROTEIN; FLUORESCENT DYE; MUCIN 1; N (2 HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER; NEAR INFRARED FLUORESCENCE DYE; UNCLASSIFIED DRUG; ACRYLAMIDE DERIVATIVE; N-(2-HYDROXYPROPYL)METHACRYLAMIDE; PEPTIDE; CONTRAST MEDIUM; FLUORESCEIN ISOTHIOCYANATE; N (2 HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER (EPPT1) IR 783;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER DIAGNOSIS; COLON MUCOSA; COLONOSCOPY; COLORECTAL CANCER; COLORECTAL CANCER CELL LINE; CONTROLLED STUDY; DRUG CONJUGATION; EPITHELIAL CANCER CELL LINE; FEMALE; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRACOLONIC DRUG ADMINISTRATION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; COLON; COLORECTAL NEOPLASMS; DIAGNOSTIC USE; DRUG DELIVERY SYSTEM; FLUORESCENCE IMAGING; METABOLISM; MOLECULAR GENETICS; NUDE MOUSE; PATHOLOGY; PROCEDURES; RECTUM; TUMOR CELL LINE; ANIMAL CELL; CANCER CELL; CANCER TISSUE; DRUG MECHANISM; DRUG PROTEIN BINDING; DRUG SELECTIVITY; EPITHELIUM CELL; IN VITRO STUDY; MOLECULAR PROBE; NEAR INFRARED FLUORESCENCE; NEAR INFRARED SPECTROSCOPY;

ACRYLAMIDES; AMINO ACID SEQUENCE; ANIMALS; CELL LINE, TUMOR; COLON; COLONOSCOPY; COLORECTAL NEOPLASMS; DRUG DELIVERY SYSTEMS; FEMALE; FLUORESCENT DYES; HUMANS; MICE; MICE, NUDE; MOLECULAR SEQUENCE DATA; MUCIN-1; OPTICAL IMAGING; PEPTIDES; RECTUM;

EID: 84905374869     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.06.058     Document Type: Article

References (30)

1. R. Siegel, C. Desantis, and A. Jemal Colorectal cancer statistics, 2014 CA Cancer J. Clin. 64 2014 104 117
2. J.C. van Rijn, J.B. Reitsma, J. Stoker, P.M. Bossuyt, S.J. van Deventer, and E. Dekker Polyp miss rate determined by tandem colonoscopy: a systematic review Am. J. Gastroenterol. 101 2006 343 350 (Pubitemid 43381678)
3. W.H. Kim, J.H. Suh, T.I. Kim, S.K. Shin, Y.H. Paik, H.W. Chung, D.Y. Kim, J.H. Jeong, J.K. Kang, H. Kim, and N.K. Kim Colorectal flat neoplasia Dig. Liver Dis. 35 2003 165 171 (Pubitemid 40668460)
4. J.V. Frangioni In vivo near-infrared fluorescence imaging Curr. Opin. Chem. Biol. 7 2003 626 634 (Pubitemid 37315800)
5. A.M. Smith, M.C. Mancini, and S. Nie Bioimaging: second window for in vivo imaging Nat. Nanotechnol. 4 2009 710 711
6. K. Welsher, Z. Liu, S.P. Sherlock, J.T. Robinson, Z. Chen, D. Daranciang, and H. Dai A route to brightly fluorescent carbon nanotubes for near-infrared imaging in mice Nat. Nanotechnol. 4 2009 773 780
7. K. Welsher, S.P. Sherlock, and H. Dai Deep-tissue anatomical imaging of mice using carbon nanotube fluorophores in the second near-infrared window Proc. Natl. Acad. Sci. U. S. A. 108 2011 8943 8948
8. D.J. Hawrysz, and E.M. Sevick-Muraca Developments toward diagnostic breast cancer imaging using near-infrared optical measurements and fluorescent contrast agents Neoplasia 2 2000 388 417 (Pubitemid 32044786)
9. V. Ntziachristos, C. Bremer, and R. Weissleder Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging Eur. Radiol. 13 2003 195 208 (Pubitemid 36790510)
10. M.R. Lisy, A. Hartung, C. Lang, D. Schuler, W. Richter, J.R. Reichenbach, W.A. Kaiser, and I. Hilger Fluorescent bacterial magnetic nanoparticles as bimodal contrast agents Invest. Radiol. 42 2007 235 241 (Pubitemid 46398862)
11. Z. Yang, S. Zheng, W.J. Harrison, J. Harder, X. Wen, J.G. Gelovani, A. Qiao, and C. Li Long-circulating near-infrared fluorescence core-cross-linked polymeric micelles: synthesis, characterization, and dual nuclear/optical imaging Biomacromolecules 8 2007 3422 3428 (Pubitemid 350193742)
12. H. Maeda, J. Wu, T. Sawa, Y. Matsumura, and K. Hori Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review J. Control. Release 65 2000 271 284 (Pubitemid 30122932)
13. Y. Matsumura, and H. Maeda A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs Cancer Res. 46 1986 6387 6392 (Pubitemid 17221789)
14. Z. Yang, J. Leon, M. Martin, J.W. Harder, R. Zhang, D. Liang, W. Lu, M. Tian, J.G. Gelovani, A. Qiao, and C. Li Pharmacokinetics and biodistribution of near-infrared fluorescence polymeric nanoparticles Nanotechnology 20 2009 165101
15. S. Kunjachan, F. Gremse, B. Theek, P. Koczera, R. Pola, M. Pechar, T. Etrych, K. Ulbrich, G. Storm, F. Kiessling, and T. Lammers Noninvasive optical imaging of nanomedicine biodistribution ACS Nano 7 2012 252 262
16. J. Burchell, and J. Taylor-Papadimitriou Effect of modification of carbohydrate side chains on the reactivity of antibodies with core-protein epitopes of the MUC1 gene product Epithelial Cell Biol. 2 1993 155 162 (Pubitemid 23295601)
17. A. Moore, Z. Medarova, A. Potthast, and G. Dai In vivo targeting of underglycosylated MUC-1 tumor antigen using a multimodal imaging probe Cancer Res. 64 2004 1821 1827 (Pubitemid 38428707)
18. W. Wang, S. Ke, S. Kwon, S. Yallampalli, A.G. Cameron, K.E. Adams, M.E. Mawad, and E.M. Sevick-Muraca A new optical and nuclear dual-labeled imaging agent targeting interleukin 11 receptor alpha-chain Bioconjug. Chem. 18 2007 397 402 (Pubitemid 46493510)
19. J. Drobník, J. Kopeček, J. Labský, P. Rejmanová, J. Exner, V. Saudek, and J. Kálal Enzymatic cleavage of side chains of synthetic water-soluble polymers Makromol. Chem. 177 1976 2833 2848
20. V. Omelyanenko, P. Kopeckova, C. Gentry, and J. Kopecek Targetable HPMA copolymer-adriamycin conjugates. Recognition, internalization, and subcellular fate J. Control. Release 53 1998 25 37 (Pubitemid 28218687)
21. Y. Shamay, D. Paulin, G. Ashkenasy, and A. David E-selectin binding peptide-polymer-drug conjugates and their selective cytotoxicity against vascular endothelial cells Biomaterials 30 2009 6460 6468
22. M.V. Cespedes, C. Espina, M.A. Garcia-Cabezas, M. Trias, A. Boluda, M.T. Gomez del Pulgar, F.J. Sancho, M. Nistal, J.C. Lacal, and R. Mangues Orthotopic microinjection of human colon cancer cells in nude mice induces tumor foci in all clinically relevant metastatic sites Am. J. Pathol. 170 2007 1077 1085 (Pubitemid 47339374)
23. P. Diagaradjane, J.M. Orenstein-Cardona, N.E. Colon-Casasnovas, A. Deorukhkar, S. Shentu, N. Kuno, D.L. Schwartz, J.G. Gelovani, and S. Krishnan Imaging epidermal growth factor receptor expression in vivo: pharmacokinetic and biodistribution characterization of a bioconjugated quantum dot nanoprobe Clin. Cancer Res. 14 2008 731 741 (Pubitemid 351231154)
24. S. Cohen, and S. Margel Engineering of near IR fluorescent albumin nanoparticles for in vivo detection of colon cancer J. Nanobiotechnol. 10 2012 36
25. M. Bloch, Y. Kam, E. Yavin, D. Moradov, A. Nissan, I. Ariel, and A. Rubinstein The relative roles of charge and a recognition peptide in luminal targeting of colorectal cancer by fluorescent polyacrylamide Eur. J. Pharm. Sci. 47 2012 904 913
26. M.P. Melancon, W. Wang, Y. Wang, R. Shao, X. Ji, J.G. Gelovani, and C. Li A novel method for imaging in vivo degradation of poly(L-glutamic acid), a biodegradable drug carrier Pharm. Res. 24 2007 1217 1224 (Pubitemid 46798898)
27. R. Aoki, S. Tanaka, K. Haruma, M. Yoshihara, K. Sumii, G. Kajiyama, F. Shimamoto, and N. Kohno MUC-1 expression as a predictor of the curative endoscopic treatment of submucosally invasive colorectal carcinoma Dis. Colon Rectum 41 1998 1262 1272 (Pubitemid 28477976)
28. C. Hanski, K. Drechsler, F.G. Hanisch, J. Sheehan, M. Manske, D. Ogorek, E. Klussmann, M.L. Hanski, M. Blank, and P.X. Xing et al. Altered glycosylation of the MUC-1 protein core contributes to the colon carcinoma-associated increase of mucin-bound sialyl-Lewis(x) expression Cancer Res. 53 1993 4082 4088 (Pubitemid 23267715)
29. X. Yang, C. Shi, R. Tong, W. Qian, H.E. Zhau, R. Wang, G. Zhu, J. Cheng, V.W. Yang, T. Cheng, M. Henary, L. Strekowski, and L.W. Chung Near IR heptamethine cyanine dye-mediated cancer imaging Clin. Cancer Res. 16 2010 2833 2844
30. B. Hagenbuch, and P.J. Meier Organic anion transporting polypeptides of the OATP/SLC21 family: phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties Pflugers Arch. 447 2004 653 665 (Pubitemid 38241451)