메뉴 건너뛰기




Volumn 58, Issue 8, 2014, Pages 4411-4419

LL-37-derived peptides eradicate multidrug-resistant Staphylococcus aureus from thermally wounded human skin equivalents

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; CAP18 LIPOPOLYSACCHARIDE-BINDING PROTEIN; INTERLEUKIN 8; PSEUDOMONIC ACID;

EID: 84905368532     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.02554-14     Document Type: Article
Times cited : (115)

References (50)
  • 1
    • 80052969407 scopus 로고    scopus 로고
    • Epidemiology of burns throughout the world. Part I: Distribution and risk factors
    • Peck MD. 2011. Epidemiology of burns throughout the world. Part I: distribution and risk factors. Burn. 37:1087-1100. http://dx.doi.org/10.1016/j. burns.2011.06.005.
    • (2011) Burn. , vol.37 , pp. 1087-1100
    • Peck, M.D.1
  • 2
    • 38349090456 scopus 로고    scopus 로고
    • Microscopic and physiologic evidence for biofilm-associated wound colonization in vivo
    • Davis SC, Ricotti C, Cazzaniga A, Welsh E, Eaglstein WH, Mertz PM. 2008. Microscopic and physiologic evidence for biofilm-associated wound colonization in vivo. Wound Repair Regen. 16:23-29. http://dx.doi.org/10.1111/j.1524-475X. 2007.00303.x.
    • (2008) Wound Repair Regen. , vol.16 , pp. 23-29
    • Davis, S.C.1    Ricotti, C.2    Cazzaniga, A.3    Welsh, E.4    Eaglstein, W.H.5    Mertz, P.M.6
  • 3
    • 2442447453 scopus 로고    scopus 로고
    • Changes of microbial flora and wound colonization in burned patients
    • Erol S, Altoparlak U, Akcay MN, Celebi F, Parlak M. 2004. Changes of microbial flora and wound colonization in burned patients. Burn. 30:357-361. http://dx.doi.org/10.1016/j.burns.2003.12.013.
    • (2004) Burn. , vol.30 , pp. 357-361
    • Erol, S.1    Altoparlak, U.2    Akcay, M.N.3    Celebi, F.4    Parlak, M.5
  • 4
    • 69949132474 scopus 로고    scopus 로고
    • The role of nasal carriage in Staphylococcus aureus burn wound colonization
    • Kooistra-Smid M, Nieuwenhuis M, van Belkum A, Verbrugh H. 2009. The role of nasal carriage in Staphylococcus aureus burn wound colonization. FEMS Immunol. Med. Microbiol. 57:1-13. http://dx.doi.org/10.1111/j.1574-695X.2009. 00565.x.
    • (2009) FEMS Immunol. Med. Microbiol. , vol.57 , pp. 1-13
    • Kooistra-Smid, M.1    Nieuwenhuis, M.2    Van Belkum, A.3    Verbrugh, H.4
  • 6
    • 0024365435 scopus 로고
    • Efficacy of mupirocin in methicillin-resistant Staphylococcus aureus burn wound infection
    • Rode H, Hanslo D, de Wet PM, Millar AJ, Cywes S. 1989. Efficacy of mupirocin in methicillin-resistant Staphylococcus aureus burn wound infection. Antimicrob. Agents Chemother. 33:1358-1361. http://dx.doi.org/10.1128/AAC.33.8. 1358.
    • (1989) Antimicrob. Agents Chemother. , vol.33 , pp. 1358-1361
    • Rode, H.1    Hanslo, D.2    De Wet, P.M.3    Millar, A.J.4    Cywes, S.5
  • 7
    • 0031417432 scopus 로고    scopus 로고
    • Povidone iodine plus neosporin in superficial burns-a continuing study
    • Sinha R, Agarwal RK, Agarwal M. 1997. Povidone iodine plus neosporin in superficial burns-a continuing study. Burn. 23:626-628. http://dx.doi.org/10. 1016/S0305-4179(97)00069-7.
    • (1997) Burn. , vol.23 , pp. 626-628
    • Sinha, R.1    Agarwal, R.K.2    Agarwal, M.3
  • 8
    • 0031931007 scopus 로고    scopus 로고
    • The emergence of mupirocin resistance: A challenge to infection control and antibiotic prescribing practice
    • Cookson BD. 1998. The emergence of mupirocin resistance: a challenge to infection control and antibiotic prescribing practice. J. Antimicrob. Chemother. 41:11-18.
    • (1998) J. Antimicrob. Chemother. , vol.41 , pp. 11-18
    • Cookson, B.D.1
  • 9
    • 84887240742 scopus 로고    scopus 로고
    • Clinical relevance of mupirocin resistance in Staphylococcus aureus
    • Hetem DJ, Bonten MJ. 2013. Clinical relevance of mupirocin resistance in Staphylococcus aureus. J. Hosp. Infect. 85:249-256. http://dx.doi.org/10.1016/j. jhin.2013.09.006.
    • (2013) J. Hosp. Infect. , vol.85 , pp. 249-256
    • Hetem, D.J.1    Bonten, M.J.2
  • 11
    • 0035859467 scopus 로고    scopus 로고
    • Antibiotic resistance of bacteria in biofilms
    • Stewart PS, Costerton JW. 2001. Antibiotic resistance of bacteria in biofilms. Lance. 358:135-138. http://dx.doi.org/10.1016/s0140-6736(01)05321-1.
    • (2001) Lance. , vol.358 , pp. 135-138
    • Stewart, P.S.1    Costerton, J.W.2
  • 12
    • 0033930831 scopus 로고    scopus 로고
    • Role of antibiotic penetration limitation in Klebsiella pneumoniae biofilm resistance to ampicillin and ciprofloxacin
    • Anderl JN, Franklin MJ, Stewart PS. 2000. Role of antibiotic penetration limitation in Klebsiella pneumoniae biofilm resistance to ampicillin and ciprofloxacin. Antimicrob. Agents Chemother. 44:1818-1824. http://dx.doi.org/10. 1128/AAC.44.7.1818-1824.2000.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 1818-1824
    • Anderl, J.N.1    Franklin, M.J.2    Stewart, P.S.3
  • 13
    • 77951031903 scopus 로고    scopus 로고
    • Effect of chlorhexidine whole-body bathing on hospital-acquired infections among trauma patients
    • Evans HL, Dellit TH, Chan J, Nathens AB, Maier RV, Cuschieri J. 2010. Effect of chlorhexidine whole-body bathing on hospital-acquired infections among trauma patients. Arch. Surg. 145:240-246. http://dx.doi.org/10.1001/archsurg. 2010.5.
    • (2010) Arch. Surg. , vol.145 , pp. 240-246
    • Evans, H.L.1    Dellit, T.H.2    Chan, J.3    Nathens, A.B.4    Maier, R.V.5    Cuschieri, J.6
  • 14
    • 84868197457 scopus 로고    scopus 로고
    • Comparison of the antibacterial effect of silver sulfadiazine 1%, mupirocin 2%, Acticoat and octenidine dihydrochloride in a fullthickness rat burn model contaminated with multi drug resistant Acinetobacter baumannii
    • Selcuk CT, Durgun M, Ozalp B, Tekin A, Tekin R, Akçay C, Alabalik U. 2012. Comparison of the antibacterial effect of silver sulfadiazine 1%, mupirocin 2%, Acticoat and octenidine dihydrochloride in a fullthickness rat burn model contaminated with multi drug resistant Acinetobacter baumannii. Burn. 38:1204-1209. http://dx.doi.org/10.1016/j.burns.2012.04.009.
    • (2012) Burn. , vol.38 , pp. 1204-1209
    • Selcuk, C.T.1    Durgun, M.2    Ozalp, B.3    Tekin, A.4    Tekin, R.5    Akçay, C.6    Alabalik, U.7
  • 15
    • 0037335205 scopus 로고    scopus 로고
    • The cathelicidin anti-microbial peptide LL-37 is involved in re-epithelialization of human skin wounds and is lacking in chronic ulcer epithelium
    • Heilborn JD, Nilsson MF, Kratz G, Weber G, Sørensen O, Borregaard N, Ståhle-Bäckdahl M. 2003. The cathelicidin anti-microbial peptide LL-37 is involved in re-epithelialization of human skin wounds and is lacking in chronic ulcer epithelium. J. Invest. Dermatol. 120:379-389. http://dx.doi.org/10.1046/j.1523-1747.2003.12069.x.
    • (2003) J. Invest. Dermatol. , vol.120 , pp. 379-389
    • Heilborn, J.D.1    Nilsson, M.F.2    Kratz, G.3    Weber, G.4    Sørensen, O.5    Borregaard, N.6    Ståhle-Bäckdahl, M.7
  • 18
    • 0037165196 scopus 로고    scopus 로고
    • Antimicrobial peptides of multicellular organisms
    • Zasloff M. 2002. Antimicrobial peptides of multicellular organisms. Natur. 415:389-395. http://dx.doi.org/10.1038/415389a.
    • (2002) Natur. , vol.415 , pp. 389-395
    • Zasloff, M.1
  • 20
    • 79956219045 scopus 로고    scopus 로고
    • Natural and synthetic cathelicidin peptides with anti-microbial and anti-biofilm activity against Staphylococcus aureus
    • Dean SN, Bishop BM, van Hoek ML. 2011. Natural and synthetic cathelicidin peptides with anti-microbial and anti-biofilm activity against Staphylococcus aureus. BMC Microbiol. 11:114. http://dx.doi.org/10.1186/1471-2180-11-114.
    • (2011) BMC Microbiol. , vol.11 , pp. 114
    • Dean, S.N.1    Bishop, B.M.2    Van Hoek, M.L.3
  • 21
    • 0037960231 scopus 로고    scopus 로고
    • Antimicrobial and protease inhibitory functions of the human cathelicidin (hCAP18/LL-37) prosequence
    • Zaiou M, Nizet V, Gallo RL. 2003. Antimicrobial and protease inhibitory functions of the human cathelicidin (hCAP18/LL-37) prosequence. J. Invest. Dermatol. 120:810-816. http://dx.doi.org/10.1046/j.1523-1747.2003.12132.x.
    • (2003) J. Invest. Dermatol. , vol.120 , pp. 810-816
    • Zaiou, M.1    Nizet, V.2    Gallo, R.L.3
  • 22
    • 51949104801 scopus 로고    scopus 로고
    • Human host defense peptide LL-37 prevents bacterial biofilm formation
    • Overhage J, Campisano A, Bains M, Torfs EC, Rehm BH, Hancock RE. 2008. Human host defense peptide LL-37 prevents bacterial biofilm formation. Infect. Immun. 76:4176-4182. http://dx.doi.org/10.1128/IAI.00318-08.
    • (2008) Infect. Immun. , vol.76 , pp. 4176-4182
    • Overhage, J.1    Campisano, A.2    Bains, M.3    Torfs, E.C.4    Rehm, B.H.5    Hancock, R.E.6
  • 26
    • 33645420007 scopus 로고    scopus 로고
    • Development of novel LL-37 derived antimicrobial peptides with LPS and LTA neutralizing and antimicrobial activities for therapeutic application
    • Nell MJ, Tjabringa GS, Wafelman AR, Verrijk R, Hiemstra PS, Drijfhout JW, Grote JJ. 2006. Development of novel LL-37 derived antimicrobial peptides with LPS and LTA neutralizing and antimicrobial activities for therapeutic application. Peptide. 27:649-660. http://dx.doi.org/10.1016/j.peptides.2005.09. 016.
    • (2006) Peptide. , vol.27 , pp. 649-660
    • Nell, M.J.1    Tjabringa, G.S.2    Wafelman, A.R.3    Verrijk, R.4    Hiemstra, P.S.5    Drijfhout, J.W.6    Grote, J.J.7
  • 28
    • 84877318780 scopus 로고    scopus 로고
    • Antimicrobial peptides stage a comeback
    • Fox JL. 2013. Antimicrobial peptides stage a comeback. Nat. Biotechnol. 31:379-382. http://dx.doi.org/10.1038/nbt.2572.
    • (2013) Nat. Biotechnol. , vol.31 , pp. 379-382
    • Fox, J.L.1
  • 29
    • 84883688534 scopus 로고    scopus 로고
    • The human cathelicidin antimicrobial peptide LL-37 as a potential treatment for polymicrobial infected wounds
    • Duplantier AJ, van Hoek ML. 2013. The human cathelicidin antimicrobial peptide LL-37 as a potential treatment for polymicrobial infected wounds. Front. Immunol. 4:143. http://dx.doi.org/10.3389/fimmu.2013.00143.
    • (2013) Front. Immunol. , vol.4 , pp. 143
    • Duplantier, A.J.1    Van Hoek, M.L.2
  • 30
    • 84892408700 scopus 로고    scopus 로고
    • Inflammatory and antimicrobial responses to methicillin-resistant Staphylococcus aureus in an in vitro wound infection model
    • Haisma EM, Rietveld M, de Breij A, van Dissel JT, El Ghalbzouri A, Nibbering PH. 2013. Inflammatory and antimicrobial responses to methicillin-resistant Staphylococcus aureus in an in vitro wound infection model. PLoS On. 8:e82800. http://dx.doi.org/10.1371/journal.pone.0082800.
    • (2013) PLoS On. , vol.8
    • Haisma, E.M.1    Rietveld, M.2    De Breij, A.3    Van Dissel, J.T.4    El Ghalbzouri, A.5    Nibbering, P.H.6
  • 32
    • 57449114952 scopus 로고    scopus 로고
    • Differential innate immune responses of a living skin equivalent model colonized by Staphylococcus epidermidis or Staphylococcus aureus
    • Holland DB, Bojar RA, Farrar MD, Holland KT. 2009. Differential innate immune responses of a living skin equivalent model colonized by Staphylococcus epidermidis or Staphylococcus aureus. FEMS Microbiol. Lett. 290:149-155. http://dx.doi.org/10.1111/j.1574-6968.2008.01402.x.
    • (2009) FEMS Microbiol. Lett. , vol.290 , pp. 149-155
    • Holland, D.B.1    Bojar, R.A.2    Farrar, M.D.3    Holland, K.T.4
  • 33
    • 37349100988 scopus 로고    scopus 로고
    • Microbial colonization of an in vitro model of a tissue engineered human skin equivalent-a novel approach
    • Holland DB, Bojar RA, Jeremy AH, Ingham E, Holland KT. 2008. Microbial colonization of an in vitro model of a tissue engineered human skin equivalent-a novel approach. FEMS Microbiol. Lett. 279:110-115. http://dx.doi.org/10.1111/j. 1574-6968.2007.01021.x.
    • (2008) FEMS Microbiol. Lett. , vol.279 , pp. 110-115
    • Holland, D.B.1    Bojar, R.A.2    Jeremy, A.H.3    Ingham, E.4    Holland, K.T.5
  • 34
    • 72849106527 scopus 로고    scopus 로고
    • Staphylococcus aureus biofilm formation at the physiologic glucose concentration depends on the S. Aureus lineage
    • Croes S, Deurenberg RH, Boumans ML, Beisser PS, Neef C, Stobberingh EE. 2009. Staphylococcus aureus biofilm formation at the physiologic glucose concentration depends on the S. aureus lineage. BMC Microbiol. 9:229. http://dx.doi.org/10.1186/1471-2180-9-229.
    • (2009) BMC Microbiol. , vol.9 , pp. 229
    • Croes, S.1    Deurenberg, R.H.2    Boumans, M.L.3    Beisser, P.S.4    Neef, C.5    Stobberingh, E.E.6
  • 35
    • 0034005677 scopus 로고    scopus 로고
    • Multilocus sequence typing for characterization of methicillin-resistant and methicillin-susceptible clones of Staphylococcus aureus
    • Enright MC, Day NP, Davies CE, Peacock SJ, Spratt BG. 2000. Multilocus sequence typing for characterization of methicillin-resistant and methicillin-susceptible clones of Staphylococcus aureus. J. Clin. Microbiol. 38:1008-1015.
    • (2000) J. Clin. Microbiol. , vol.38 , pp. 1008-1015
    • Enright, M.C.1    Day, N.P.2    Davies, C.E.3    Peacock, S.J.4    Spratt, B.G.5
  • 38
    • 0030867922 scopus 로고    scopus 로고
    • The formation of competent barrier lipids in reconstructed human epidermis requires the presence of vitamin C
    • Ponec M, Weerheim A, Kempenaar J, Mulder A, Gooris GS, Bouwstra J, Mommaas AM. 1997. The formation of competent barrier lipids in reconstructed human epidermis requires the presence of vitamin C. J. Invest. Dermatol. 109:348-355. http://dx.doi.org/10.1111/1523-1747.ep12336024.
    • (1997) J. Invest. Dermatol. , vol.109 , pp. 348-355
    • Ponec, M.1    Weerheim, A.2    Kempenaar, J.3    Mulder, A.4    Gooris, G.S.5    Bouwstra, J.6    Mommaas, A.M.7
  • 39
    • 44749093939 scopus 로고    scopus 로고
    • Leiden reconstructed human epidermal model as a tool for the evaluation of the skin corrosion and irritation potential according to the ECVAM guidelines
    • El Ghalbzouri A, Siamari R, Willemze R, Ponec M. 2008. Leiden reconstructed human epidermal model as a tool for the evaluation of the skin corrosion and irritation potential according to the ECVAM guidelines. Toxicol. In Vitr. 22:1311-1320. http://dx.doi.org/10.1016/j.tiv.2008.03.012.
    • (2008) Toxicol. In Vitr. , vol.22 , pp. 1311-1320
    • El Ghalbzouri, A.1    Siamari, R.2    Willemze, R.3    Ponec, M.4
  • 40
    • 55049123443 scopus 로고    scopus 로고
    • Mupirocin ointment for preventing Staphylococcus aureus infections in nasal carriers
    • van Rijen M, Bonten M, Wenzel R, Kluytmans J. 2008. Mupirocin ointment for preventing Staphylococcus aureus infections in nasal carriers. Cochrane Database Syst. Rev. (4): CD006216. http://dx.doi.org/10.1002/14651858.CD006216. pub2.
    • (2008) Cochrane Database Syst. Rev. , Issue.4
    • Van Rijen, M.1    Bonten, M.2    Wenzel, R.3    Kluytmans, J.4
  • 41
    • 84887412947 scopus 로고    scopus 로고
    • Little peptide, big effects: The role of LL-37 in inflammation and autoimmune disease
    • Kahlenberg JM, Kaplan MJ. 2013. Little peptide, big effects: the role of LL-37 in inflammation and autoimmune disease. J. Immunol. 191:4895-4901. http://dx.doi.org/10.4049/jimmunol.1302005.
    • (2013) J. Immunol. , vol.191 , pp. 4895-4901
    • Kahlenberg, J.M.1    Kaplan, M.J.2
  • 42
    • 0028844134 scopus 로고
    • Cathelicidins: A novel protein family with a common proregion and a variable C-terminal antimicrobial domain
    • Zanetti M, Gennaro R, Romeo D. 1995. Cathelicidins: a novel protein family with a common proregion and a variable C-terminal antimicrobial domain. FEBS Lett. 374:1-5.
    • (1995) FEBS Lett. , vol.374 , pp. 1-5
    • Zanetti, M.1    Gennaro, R.2    Romeo, D.3
  • 45
    • 84892408700 scopus 로고    scopus 로고
    • Inflammatory and antimicrobial responses to methicillinresistant Staphylococcus aureus in an in vitro wound infection model
    • Haisma EM, Rietveld MH, de Breij A, van Dissel JT, El Ghalbzouri A, Nibbering PH. 2013. Inflammatory and antimicrobial responses to methicillinresistant Staphylococcus aureus in an in vitro wound infection model. PLoS On. 8:e82800. http://dx.doi.org/10.1371/journal.pone.0082800.
    • (2013) PLoS On. , vol.8
    • Haisma, E.M.1    Rietveld, M.H.2    De Breij, A.3    Van Dissel, J.T.4    El Ghalbzouri, A.5    Nibbering, P.H.6
  • 46
    • 34447544341 scopus 로고    scopus 로고
    • Albumin binding of short cationic antimicrobial micropeptides and its influence on the in vitro bactericidal effect
    • Svenson J, Brandsdal BO, Stensen W, Svendsen JS. 2007. Albumin binding of short cationic antimicrobial micropeptides and its influence on the in vitro bactericidal effect. J. Med. Chem. 50:3334-3339. http://dx.doi.org/10.1021/ jm0703542.
    • (2007) J. Med. Chem. , vol.50 , pp. 3334-3339
    • Svenson, J.1    Brandsdal, B.O.2    Stensen, W.3    Svendsen, J.S.4
  • 49
    • 84884959307 scopus 로고    scopus 로고
    • Human cathelicidin LL-37-derived peptide IG-19 confers protection in a murine model of collagen-induced arthritis
    • Chow LN, Choi KY, Piyadasa H, Bossert M, Uzonna J, Klonisch T, Mookherjee N. 2014. Human cathelicidin LL-37-derived peptide IG-19 confers protection in a murine model of collagen-induced arthritis. Mol. Immunol. 57:86-92. http://dx.doi.org/10.1016/j.molimm.2013.08.011.
    • (2014) Mol. Immunol. , vol.57 , pp. 86-92
    • Chow, L.N.1    Choi, K.Y.2    Piyadasa, H.3    Bossert, M.4    Uzonna, J.5    Klonisch, T.6    Mookherjee, N.7
  • 50
    • 84869211892 scopus 로고    scopus 로고
    • In vitro activities of antibiotics and antimicrobial cationic peptides alone and in combination against methicillinresistant Staphylococcus aureus biofilms
    • Mataraci E, Dosler S. 2012. In vitro activities of antibiotics and antimicrobial cationic peptides alone and in combination against methicillinresistant Staphylococcus aureus biofilms. Antimicrob. Agents Chemother. 56:6366-6371. http://dx.doi.org/10.1128/AAC.01180-12.
    • (2012) Antimicrob. Agents Chemother. , vol.56 , pp. 6366-6371
    • Mataraci, E.1    Dosler, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.