Keratan sulfate expression is associated with activation of a subpopulation of microglia/macrophages in Wallerian degeneration

Neuroscience Letters

Volumn 579, Issue , 2014, Pages 80-85

  Shinjo, Ryuichi ^a   Imagama, Shiro ^a   Ito, Zenya ^a   Ando, Kei ^a   Nishida, Yoshihiro ^a   Ishiguro, Naoki ^a   Kadomatsu, Kenji ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Keratan sulfate; Macrophage; Microglia; Spinal cord injury; Spinal cord lateral hemisection; WALLERIAN degeneration

Indexed keywords

ANTIGEN; ARGINASE 1; CD206 ANTIGEN; CD68 ANTIGEN; CD86 ANTIGEN; KERATAN SULFATE; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; AIF1 PROTEIN, MOUSE; CALCIUM BINDING PROTEIN; CD68 ANTIGEN, HUMAN; DIFFERENTIATION ANTIGEN; INTERLEUKIN 1BETA; LEUKOCYTE ANTIGEN;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL ACTIVATION; CELL SUBPOPULATION; DISEASE ASSOCIATION; FEMALE; LUMBAR SPINE; MACROPHAGE; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPINAL CORD INJURY; WALLERIAN DEGENERATION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; MACROPHAGE ACTIVATION; METABOLISM; PATHOLOGY;

ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; CALCIUM-BINDING PROTEINS; FEMALE; INTERLEUKIN-1BETA; KERATAN SULFATE; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED C57BL; MICROFILAMENT PROTEINS; MICROGLIA; SPINAL CORD INJURIES; WALLERIAN DEGENERATION;

EID: 84905253467     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2014.07.018     Document Type: Article

References (18)

1. Buss A., Schwab M.E. Sequential loss of myelin proteins during Wallerian degeneration in the rat spinal cord. Glia 2003, 42:424-432.
2. Carlton S.M., Du J., Tan H.Y., Nesic O., Hargett G.L., Bopp A.C., Yamani A., Lin Q., Willis W.D., Hulsebosch C.E. Peripheral and central sensitization in remote spinal cord regions contribute to central neuropathic pain after spinal cord injury. Pain 2009, 147:265-276.
3. David S., Kroner A. Repertoire of microglial and macrophage responses after spinal cord injury. Nat. Rev. Neurosci. 2011, 12:388-399.
4. George R.G.J. Delayed macrophage responses and myelin clearance during Wallerian degeneration in the central nervous system. The dorsal radiculotomy model. Exp. Neurol. 1994, 129:225-236.
5. Hirano K., Ohgomori T., Kobayashi K., Tanaka F., Matsumoto T., Natori T., Matsuyama Y., Uchimura K., Sakamoto K., Takeuchi H., Hirakawa A., Suzumura A., Sobue G., Ishiguro N., Imagama S., Kadomatsu K. Ablation of keratan sulfate accelerates early phase pathogenesis of ALS. PLOS ONE 2013, 8:e66969.
6. Imagama S., Sakamoto K., Tauchi R., Shinjo R., Ohgomori T., Ito Z., Zhang H., Nishida Y., Asami N., Takeshita S., Sugiura N., Watanabe H., Yamashita T., Ishiguro N., Matsuyama Y., Kadomatsu K. Keratan sulfate restricts neural plasticity after spinal cord injury. J. Neurosci.: Off. J. Soc. Neurosci. 2011, 31:17091-17102.
7. Ito Z., Sakamoto K., Imagama S., Matsuyama Y., Zhang H., Hirano K., Ando K., Yamashita T., Ishiguro N., Kadomatsu K. N-acetylglucosamine 6-O-sulfotransferase-1-deficient mice show better functional recovery after spinal cord injury. J. Neurosci.: Off. J. Soc. Neurosci. 2010, 30:5937-5947.
8. Jones L.L.T.M. Spinal cord injury elicits expression of keratan sulfate proteoglycans by macrophages, reactive microglia, and oligodendrocyte progenitors. J. Neurosci. 2002, 22:4611-4624.
9. Kigerl K.A., Gensel J.C., Ankeny D.P., Alexander J.K., Donnelly D.J., Popovich P.G. Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord. J. Neurosci.: Off. J. Soc. Neurosci. 2009, 29:13435-13444.
10. Koshinaga M., Whittemore S.R. The temporal and spatial activation of microglia in fiber tracts undergoing anterograde and retrograde degeneration following spinal cord lesion. J. Neurotrauma 1995, 12:209-222.
11. Parkhurst C.N., Yang G., Ninan I., Savas J.N., Yates J.R., Lafaille J.J., Hempstead B.L., Littman D.R., Gan W.B. Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor. Cell 2013, 155:1596-1609.
12. Ueno M., Fujita Y., Tanaka T., Nakamura Y., Kikuta J., Ishii M., Yamashita T., Layer V cortical neurons require microglial support for survival during postnatal development. Nat. Neurosci. 2013, 16:543-551.
13. Wake H., Moorhouse A.J., Jinno S., Kohsaka S., Nabekura J. Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals. J. Neurosci.: Off. J. Soc. Neurosci. 2009, 29:3974-3980.
14. Waller A. Experiments on the section of the glossopharyngeal and hypoglossal nerves of the frog, and observations of the alterations produced thereby in the structure of their primitive fibres. Philos. Trans. R. Soc. Lond. 1850, 140:423-429.
15. Wang J.T., Medress Z.A., Barres B.A. Axon degeneration: molecular mechanisms of a self-destruction pathway. J. Cell Biol. 2012, 196:7-18.
16. Wang L., Hu B., Wong W.M., Lu P., Wu W., Xu X.M. Glial and axonal responses in areas of Wallerian degeneration of the corticospinal and dorsal ascending tracts after spinal cord dorsal funiculotomy. Neuropathol.: Off. J. Jpn. Soc. Neuropathol. 2009, 29:230-241.
17. Watanabe T., Yamamoto T., Abe Y., Saito N., Kumagai T., Kayama H. Differential activation of microglia after experimental spinal cord injury. J. Neurotrauma 1999, 16:255-265.
18. Zhang H., Uchimura K., Kadomatsu K. Brain keratan sulfate and glial scar formation. Ann. N. Y. Acad. Sci. 2006, 1086:81-90.