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Volumn 28, Issue 8, 2014, Pages 1265-1275

FKBP51 controls cellular adipogenesis through p38 kinase-mediated phosphorylation of GRα and PPARγ

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; CD36 ANTIGEN; FATTY ACID SYNTHASE; FK 506 BINDING PROTEIN; FK 506 BINDING PROTEIN 51; GLUCOCORTICOID RECEPTOR ALPHA; LIPID; MITOGEN ACTIVATED PROTEIN KINASE P38; PERILIPIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHOSPHOTRANSFERASE INHIBITOR; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; GLUCOCORTICOID RECEPTOR; PROTEIN KINASE B; TACROLIMUS BINDING PROTEIN 5;

EID: 84905245970     PISSN: 08888809     EISSN: 19449917     Source Type: Journal    
DOI: 10.1210/me.2014-1022     Document Type: Article
Times cited : (44)

References (32)
  • 1
    • 1942518840 scopus 로고    scopus 로고
    • PPARs and the complex journey to obesity
    • Evans RM, Barish GD, Wang YX. PPARs and the complex journey to obesity. Nat Med. 2004;10:355-361
    • (2004) Nat Med , vol.10 , pp. 355-361
    • Evans, R.M.1    Barish, G.D.2    Wang, Y.X.3
  • 2
    • 28944446431 scopus 로고    scopus 로고
    • The many faces of PPARγ
    • Lehrke M, Lazar MA. The many faces of PPARγ. Cell. 2005;123: 993-999
    • (2005) Cell , vol.123 , pp. 993-999
    • Lehrke, M.1    Lazar, M.A.2
  • 3
    • 34447618831 scopus 로고    scopus 로고
    • PPARs and their metabolic modulation: New mechanisms for transcriptional regulation?
    • Ahmed W, Ziouzenkova O, Brown J, et al. PPARs and their metabolic modulation: new mechanisms for transcriptional regulation? J Intern Med. 2007;262:184-198
    • (2007) J Intern Med , vol.262 , pp. 184-198
    • Ahmed, W.1    Ziouzenkova, O.2    Brown, J.3
  • 4
    • 34547885436 scopus 로고    scopus 로고
    • Glucocorticoids, metabolism and metabolic diseases
    • Vegiopoulos A, Herzig S. Glucocorticoids, metabolism and metabolic diseases. Mol Cell Endocrinol. 2007;275:43-61
    • (2007) Mol Cell Endocrinol , vol.275 , pp. 43-61
    • Vegiopoulos, A.1    Herzig, S.2
  • 5
    • 67749088181 scopus 로고    scopus 로고
    • Direct effect of glucocorticoids on lipolysis in adipocytes
    • Xu C, He J, Jiang H, et al. Direct effect of glucocorticoids on lipolysis in adipocytes. Mol Endocrinol. 2009;23:1161-1170
    • (2009) Mol Endocrinol , vol.23 , pp. 1161-1170
    • Xu, C.1    He, J.2    Jiang, H.3
  • 6
    • 64349124080 scopus 로고    scopus 로고
    • Endurance exercise training increases adipose tissue glucocorticoid exposure: Adaptations that facilitate lipolysis
    • Campbell JE, Fediuc S, Hawke TJ, Riddell MC. Endurance exercise training increases adipose tissue glucocorticoid exposure: adaptations that facilitate lipolysis. Metabolism. 2009;58:651-660
    • (2009) Metabolism , vol.58 , pp. 651-660
    • Campbell, J.E.1    Fediuc, S.2    Hawke, T.J.3    Riddell, M.C.4
  • 7
    • 83355166922 scopus 로고    scopus 로고
    • Protein phosphatase 5 mediates lipid metabolism through reciprocal control of glucocorticoid receptor and peroxisome proliferator-activated receptor-γ (PPARγ)
    • Hinds TD Jr, Stechschulte LA, Cash HA, et al. Protein phosphatase 5 mediates lipid metabolism through reciprocal control of glucocorticoid receptor and peroxisome proliferator-activated receptor-γ (PPARγ). J Biol Chem. 2011;286:42911-42922
    • (2011) J Biol Chem , vol.286 , pp. 42911-42922
    • Hinds Jr., T.D.1    Stechschulte, L.A.2    Cash, H.A.3
  • 8
    • 0038776380 scopus 로고    scopus 로고
    • Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARγ
    • Hu E, Kim JB, Sarraf P, Spiegelman BM. Inhibition of adipogenesis through MAP kinase-mediated phosphorylation of PPARγ. Science. 1996;274:2100-2103
    • (1996) Science , vol.274 , pp. 2100-2103
    • Hu, E.1    Kim, J.B.2    Sarraf, P.3    Spiegelman, B.M.4
  • 9
    • 0031057517 scopus 로고    scopus 로고
    • Transcriptional activation by peroxisome proliferator-activated receptor γ is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site
    • Adams M, Reginato MJ, Shao D, Lazar MA, Chatterjee VK. Transcriptional activation by peroxisome proliferator-activated receptor γ is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site. J Biol Chem. 1997;272:5128-5132
    • (1997) J Biol Chem , vol.272 , pp. 5128-5132
    • Adams, M.1    Reginato, M.J.2    Shao, D.3    Lazar, M.A.4    Chatterjee, V.K.5
  • 10
    • 34547589477 scopus 로고    scopus 로고
    • Modulation of PPAR activity via phosphorylation
    • Burns KA, Vanden Heuvel JP. Modulation of PPAR activity via phosphorylation. Biochim Biophys Acta. 2007;1771:952-960
    • (2007) Biochim Biophys Acta , vol.1771 , pp. 952-960
    • Burns, K.A.1    Vanden Heuvel, J.P.2
  • 12
    • 36549069731 scopus 로고    scopus 로고
    • p38MAP kinase activity is required for human primary adipocyte differentiation
    • Aouadi M, Jager J, Laurent K, et al. p38MAP kinase activity is required for human primary adipocyte differentiation. FEBS Lett. 2007;581:5591-5596
    • (2007) FEBS Lett , vol.581 , pp. 5591-5596
    • Aouadi, M.1    Jager, J.2    Laurent, K.3
  • 14
    • 69249228672 scopus 로고    scopus 로고
    • FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt
    • Pei H, Li L, Fridley BL, et al. FKBP51 affects cancer cell response to chemotherapy by negatively regulating Akt. Cancer Cell. 2009;16: 259-266
    • (2009) Cancer Cell , vol.16 , pp. 259-266
    • Pei, H.1    Li, L.2    Fridley, B.L.3
  • 16
    • 22344458207 scopus 로고    scopus 로고
    • p38 Mitogen-activated protein kinase (MAPK) is a key mediator in glucocorticoid-induced apoptosis of lymphoid cells: Correlation between p38 MAPK activation and site-specific phosphorylation of the human glucocorticoid receptor at serine 211
    • Miller AL, Webb MS, Copik AJ, et al. p38 Mitogen-activated protein kinase (MAPK) is a key mediator in glucocorticoid-induced apoptosis of lymphoid cells: correlation between p38 MAPK activation and site-specific phosphorylation of the human glucocorticoid receptor at serine 211. Mol Endocrinol. 2005;19:1569-1583
    • (2005) Mol Endocrinol , vol.19 , pp. 1569-1583
    • Miller, A.L.1    Webb, M.S.2    Copik, A.J.3
  • 17
    • 0028828951 scopus 로고
    • Identification and characterization of an immunophilin expressed during the clonal expansion phase of adipocyte differentiation
    • Yeh WC, Li TK, Bierer BE, McKnight SL. Identification and characterization of an immunophilin expressed during the clonal expansion phase of adipocyte differentiation. Proc Natl Acad Sci USA. 1995;92:11081-11085
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11081-11085
    • Yeh, W.C.1    Li, T.K.2    Bierer, B.E.3    McKnight, S.L.4
  • 18
    • 0028885873 scopus 로고
    • Rapamycin inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cells
    • Yeh WC, Bierer BE, McKnight SL. Rapamycin inhibits clonal expansion and adipogenic differentiation of 3T3-L1 cells. Proc Natl Acad Sci USA. 1995;92:11086-11090
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11086-11090
    • Yeh, W.C.1    Bierer, B.E.2    McKnight, S.L.3
  • 19
    • 84890242641 scopus 로고    scopus 로고
    • Dynamic mitochondrialnuclear redistribution of the immunophilin FKBP51 is regulated by the PKA signaling pathway to control gene expression during adipocyte differentiation
    • Toneatto J, Guber S, Charo NL, et al. Dynamic mitochondrialnuclear redistribution of the immunophilin FKBP51 is regulated by the PKA signaling pathway to control gene expression during adipocyte differentiation. J Cell Sci. 2013;126(Pt 23):5357-5368
    • (2013) J Cell Sci , vol.126 , Issue.PART 23 , pp. 5357-5368
    • Toneatto, J.1    Guber, S.2    Charo, N.L.3
  • 20
    • 33947497920 scopus 로고    scopus 로고
    • Essential role for co-chaperone Fkbp52 but not Fkbp51 in androgen receptor-mediated signaling and physiology
    • Yong W, Yang Z, Periyasamy S, et al. Essential role for co-chaperone Fkbp52 but not Fkbp51 in androgen receptor-mediated signaling and physiology. J Biol Chem. 2007;282:5026-5036
    • (2007) J Biol Chem , vol.282 , pp. 5026-5036
    • Yong, W.1    Yang, Z.2    Periyasamy, S.3
  • 21
    • 0031821520 scopus 로고    scopus 로고
    • Understanding adipocyte differentiation
    • Gregoire FM, Smas CM, Sul HS. Understanding adipocyte differentiation. Physiol Rev. 1998;78:783-809
    • (1998) Physiol Rev , vol.78 , pp. 783-809
    • Gregoire, F.M.1    Smas, C.M.2    Sul, H.S.3
  • 22
    • 0030964085 scopus 로고    scopus 로고
    • Regulation of peroxisome proliferator-activated receptor gamma activity by mitogen-activated protein kinase
    • Camp HS, Tafuri SR. Regulation of peroxisome proliferator-activated receptor gamma activity by mitogen-activated protein kinase. J Biol Chem. 1997;272:10811-10816
    • (1997) J Biol Chem , vol.272 , pp. 10811-10816
    • Camp, H.S.1    Tafuri, S.R.2
  • 23
    • 0032894240 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase phosphorylates peroxisome proliferator-activated receptor-γ1 and negatively regulates its transcriptional activity
    • Camp HS, Tafuri SR, Leff T. c-Jun N-terminal kinase phosphorylates peroxisome proliferator-activated receptor-γ1 and negatively regulates its transcriptional activity. Endocrinology. 1999;140: 392-397
    • (1999) Endocrinology , vol.140 , pp. 392-397
    • Camp, H.S.1    Tafuri, S.R.2    Leff, T.3
  • 24
    • 0037135596 scopus 로고    scopus 로고
    • Deciphering the phosphorylation "code" of the glucocorticoid receptor in vivo
    • Wang Z, Frederick J, Garabedian MJ. Deciphering the phosphorylation "code" of the glucocorticoid receptor in vivo. J Biol Chem. 2002;277:26573-26580
    • (2002) J Biol Chem , vol.277 , pp. 26573-26580
    • Wang, Z.1    Frederick, J.2    Garabedian, M.J.3
  • 25
    • 48249157970 scopus 로고    scopus 로고
    • Glucocorticoid receptor phosphorylation differentially affects target gene expression
    • Chen W, Dang T, Blind RD, et al. Glucocorticoid receptor phosphorylation differentially affects target gene expression. Mol Endocrinol. 2008;22:1754-1766
    • (2008) Mol Endocrinol , vol.22 , pp. 1754-1766
    • Chen, W.1    Dang, T.2    Blind, R.D.3
  • 26
    • 37549067731 scopus 로고    scopus 로고
    • Noncatalytic role of the FKBP52 peptidyl-prolyl isomerase domain in the regulation of steroid hormone signaling
    • Riggs DL, Cox MB, Tardif HL, Hessling M, Buchner J, Smith DF. Noncatalytic role of the FKBP52 peptidyl-prolyl isomerase domain in the regulation of steroid hormone signaling. Mol Cell Biol. 2007; 27:8658-8669
    • (2007) Mol Cell Biol , vol.27 , pp. 8658-8669
    • Riggs, D.L.1    Cox, M.B.2    Tardif, H.L.3    Hessling, M.4    Buchner, J.5    Smith, D.F.6
  • 27
    • 0029751136 scopus 로고    scopus 로고
    • The tetratricopeptide repeat domain of protein phosphatase 5 mediates binding to glucocorticoid receptor heterocomplexes and acts as a dominant negative mutant
    • Chen MS, Silverstein AM, Pratt WB, Chinkers M. The tetratricopeptide repeat domain of protein phosphatase 5 mediates binding to glucocorticoid receptor heterocomplexes and acts as a dominant negative mutant. J Biol Chem. 1996;271:32315-32320
    • (1996) J Biol Chem , vol.271 , pp. 32315-32320
    • Chen, M.S.1    Silverstein, A.M.2    Pratt, W.B.3    Chinkers, M.4
  • 28
    • 0035807022 scopus 로고    scopus 로고
    • Identification of amino acids in the tetratricopeptide repeat and C-terminal domains of protein phosphatase 5 involved in autoinhibition and lipid activation
    • Kang H, Sayner SL, Gross KL, Russell LC, Chinkers M. Identification of amino acids in the tetratricopeptide repeat and C-terminal domains of protein phosphatase 5 involved in autoinhibition and lipid activation. Biochemistry. 2001;40:10485-10490
    • (2001) Biochemistry , vol.40 , pp. 10485-10490
    • Kang, H.1    Sayner, S.L.2    Gross, K.L.3    Russell, L.C.4    Chinkers, M.5
  • 29
    • 0037197702 scopus 로고    scopus 로고
    • Identification of potential physiological activators of protein phosphatase 5
    • Ramsey AJ, Chinkers M. Identification of potential physiological activators of protein phosphatase 5. Biochemistry. 2002;41:5625-5632
    • (2002) Biochemistry , vol.41 , pp. 5625-5632
    • Ramsey, A.J.1    Chinkers, M.2
  • 30
    • 0037244704 scopus 로고    scopus 로고
    • Glucocorticoid-induced increase in lymphocytic FKBP51 messenger ribonucleic acid expression: A potential marker for glucocorticoid sensitivity, potency, and bioavailability
    • Vermeer H, Hendriks-Stegeman BI, van der Burg B, van Buul- Offers SC, Jansen M. Glucocorticoid-induced increase in lymphocytic FKBP51 messenger ribonucleic acid expression: a potential marker for glucocorticoid sensitivity, potency, and bioavailability. J Clin Endocrinol Metab. 2003;88:277-284
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 277-284
    • Vermeer, H.1    Hendriks-Stegeman, B.I.2    van der Burg, B.3    van Buul- Offers, S.C.4    Jansen, M.5
  • 31
    • 7644219666 scopus 로고    scopus 로고
    • Intronic hormone response elements mediate regulation of FKBP5 by progestins and glucocorticoids
    • Hubler TR, Scammell JG. Intronic hormone response elements mediate regulation of FKBP5 by progestins and glucocorticoids. Cell Stress Chaperones. 2004;9:243-252
    • (2004) Cell Stress Chaperones , vol.9 , pp. 243-252
    • Hubler, T.R.1    Scammell, J.G.2
  • 32
    • 34748915685 scopus 로고    scopus 로고
    • The immunophilin ligands cyclosporin a and FK506 suppress prostate cancer cell growth by androgen receptor-dependent and -independent mechanisms
    • Periyasamy S, Warrier M, Tillekeratne MP, Shou W, Sanchez ER. The immunophilin ligands cyclosporin a and FK506 suppress prostate cancer cell growth by androgen receptor-dependent and -independent mechanisms. Endocrinology. 2007;148:4716-4726.
    • (2007) Endocrinology , vol.148 , pp. 4716-4726
    • Periyasamy, S.1    Warrier, M.2    Tillekeratne, M.P.3    Shou, W.4    Sanchez, E.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.