Human mesenchymal stem cells express a myofibroblastic phenotype in vitro: Comparison to human cardiac myofibroblasts

Molecular and Cellular Biochemistry

Volumn 392, Issue 1-2, 2014, Pages 187-204

  Ngo, Melanie A ^a   Müller, Alison ^a   Li, Yun ^a   Neumann, Shannon ^a   Tian, Ganghong ^b   Dixon, Ian M C ^a   Arora, Rakesh C ^a,b   Freed, Darren H ^a,b,c  

^a UNIVERSITY OF MANITOBA   (Canada)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^c ST BONIFACE GENERAL HOSPITAL   (Canada)

Author keywords

Blebbistatin; Cardiac fibrosis; Cellular contraction; Myofibroblast contractility; Stem cell differentiation; Wound healing

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BLEBBISTATIN; COLLAGEN GEL; COLLAGEN TYPE 1; FIBRONECTIN; MYOSIN II; MYOSIN IIB; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA1; VIMENTIN; PRIMER DNA;

ARTICLE; BONE MARROW; CARDIAC MYOFIBROBLAST; CELL ISOLATION; CELL STIMULATION; CELL VIABILITY; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; COLLAGEN SYNTHESIS; CONTROLLED STUDY; GENE EXPRESSION PROFILING; GENE SILENCING; HEART MUSCLE CELL; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; HUMAN TISSUE; IN VITRO STUDY; MESENCHYMAL STEM CELL; MUSCLE CONTRACTILITY; MYOFIBROBLAST; OPEN HEART SURGERY; PHENOTYPE; PLURIPOTENCY; PRIMARY CELL CULTURE; STAINING; STEM CELL CULTURE; BIOSYNTHESIS; COMPARATIVE STUDY; CYTOLOGY; HEART MUSCLE; MESENCHYMAL STROMA CELL; METABOLISM; NUCLEOTIDE SEQUENCE; REAL TIME POLYMERASE CHAIN REACTION;

BASE SEQUENCE; COLLAGEN TYPE I; DNA PRIMERS; HUMANS; IN VITRO TECHNIQUES; MESENCHYMAL STROMAL CELLS; MYOCARDIUM; MYOFIBROBLASTS; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84905190546     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-014-2030-6     Document Type: Article

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