Non-muscle myosin IIB helps mediate TNF cell death signaling independent of actomyosin contractility (AMC)

Journal of Cellular Biochemistry

Volumn 110, Issue 6, 2010, Pages 1365-1375

  Flynn, Patrick G ^a   Helfman, David M ^a,b,c  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MIAMI   (United States)

^c Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Actin cytoskeleton; Actomyosin contractility; Apoptosis; Non muscle myosin II; Regulatory myosin light chain; Tumor necrosis factor

Indexed keywords

BLEBBISTATIN; CASPASE; CASPASE 8; CLATHRIN; CYTOCHALASIN D; DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEIN; FAS ASSOCIATED PROTEIN WITH DEATH DOMAIN; MYOSIN ADENOSINE TRIPHOSPHATASE; MYOSIN IIB; NON MUSCLE MYOSIN IIA; NON MUSCLE MYOSIN IIB; PROTEIN; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR 1; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; ENDOCYTOSIS; HELA CELL; HUMAN; HUMAN CELL; MUSCLE CONTRACTILITY; PRIORITY JOURNAL;

ACTOMYOSIN; APOPTOSIS; BLOTTING, WESTERN; CASPASE 8; CLATHRIN; ENDOCYTOSIS; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HELA CELLS; HUMANS; IMMUNOPRECIPITATION; MICROSCOPY, FLUORESCENCE; NONMUSCLE MYOSIN TYPE IIA; NONMUSCLE MYOSIN TYPE IIB; PROTEIN BINDING; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77955492524     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22653     Document Type: Article

References (42)

1. Allingham JS, Smith R, Rayment I. 2005. The structural basis of blebbistatin inhibition and specificity for myosin II. Nat Struct Mol Biol 12:378-379. (Pubitemid 43093094)
2. Arora PD, Conti MA, Ravid S, Sacks DB, Kapus A, Adelstein RS, Bresnick AR, McCulloch CA. 2008. Rap1 activation in collagen phagocytosis is dependent on nonmuscle myosin II-A. Mol Biol Cell 19:5032-5046.
3. Bai S, Liu H, Chen KH, Eksarko P, Perlman H, Moore TL, Pope RM. 2004. NF-kappaB-regulated expression of cellular FLIP protects rheumatoid arthritis synovial fibroblasts from tumor necrosis factor alpha-mediated apoptosis. Arthritis Rheum 50:3844-3855. (Pubitemid 39643931)
4. Ben-Ya'acov A, Ravid S. 2003. Epidermal growth factor-mediated transient phosphorylation and membrane localization of myosin II-B are required for efficient chemotaxis. J Biol Chem 278:40032-40040.
5. Bresnick AR. 1999. Molecular mechanisms of nonmuscle myosin-II regulation. Curr Opin Cell Biol 11:26-33. (Pubitemid 29084129)
6. Cohen O, Inbal B, Kissil JL, Raveh T, Berissi H, Spivak-Kroizaman T, Feinstein E, Kimchi A. 1999. DAP-kinase participates in TNF-alpha- and Fas-induced apoptosis and its function requires the death domain. J Cell Biol 146:141-148. (Pubitemid 29349970)
7. Coleman ML, Sahai EA, Yeo M, Bosch M, Dewar A, Olson MF. 2001. Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I. Nat Cell Biol 3:339-345. (Pubitemid 32288440)
8. Conti MA, Adelstein RS. 2008. Nonmuscle myosin II moves in new directions. J Cell Sci 121:11-18.
9. Cotter TG, Lennon SV, Glynn JM, Green DR. 1992. Microfilament-disrupting agents prevent the formation of apoptotic bodies in tumor cells undergoing apoptosis. Cancer Res 52:997-1005.
10. Croft DR, Coleman ML, Li S, Robertson D, Sullivan T, Stewart CL, Olson MF. 2005. Actin-myosin-based contraction is responsible for apoptotic nuclear disintegration. J Cell Biol 168:245-255. (Pubitemid 40248222)
11. Jin Y, Atkinson SJ, Marrs JA, Gallagher PJ. 2001. Myosin II light chain phosphorylation regulates membrane localization and apoptotic signaling of tumor necrosis factor receptor-1. J Biol Chem 276:30342-30349. (Pubitemid 37385118)
12. Kim BC, Kim HT, Mamura M, Ambudkar IS, Choi KS, Kim SJ. 2002. Tumor necrosis factor induces apoptosis in hepatoma cells by increasing Ca(2+) release from the endoplasmic reticulum and suppressing Bcl-2 expression. J Biol Chem 277:31381-31389.
13. Kivinen K, Kallajoki M, Taimen P. 2005. Caspase-3 is required in the apoptotic disintegration of the nuclear matrix. Exp Cell Res 311:62-73.
14. Kovacs M, Toth J, Hetenyi C, Malnasi-Csizmadia A, Sellers JR. 2004. Mechanism of blebbistatin inhibition of myosin II. J Biol Chem 279: 35557-35563.
15. Kuo JC, Lin JR, Staddon JM, Hosoya H, Chen RH. 2003. Uncoordinated regulation of stress fibers and focal adhesions by DAP kinase. J Cell Sci 116:4777-4790.
16. Legler DF, Micheau O, Doucey MA, Tschopp J, Bron C. 2003. Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation. Immunity 18:655-664.
17. Limouze J, Straight AF, Mitchison T, Sellers JR. 2004. Specificity of blebbistatin, an inhibitor of myosin II. J Muscle Res Cell Motil 25:337-341.
18. Ma X, Bao J, Adelstein RS. 2007. Loss of cell adhesion causes hydrocephalus in nonmuscle myosin II-B-ablated and mutated mice. Mol Biol Cell 18:2305-2312.
19. McKenzie JA, Ridley AJ. 2007. Roles of Rho/ROCK and MLCK in TNF-alpha-induced changes in endothelial morphology and permeability. J Cell Physiol 213:221-228.
20. Micheau O, Tschopp J. 2003. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114:181-190.
21. Mosselmans R, Hepburn A, Dumont JE, Fiers W, Galand P. 1988. Endocytic pathway of recombinant murine tumor necrosis factor in L-929 cells. J Immunol 141:3096-3100.
22. Petrache I, Verin AD, Crow MT, Birukova A, Liu F, Garcia JG. 2001. Differential effect of MLC kinase in TNF-alpha-induced endothelial cell apoptosis and barrier dysfunction. Am J Physiol Lung Cell Mol Physiol 280:L1168-L1178.
23. Petrache I, Birukov K, Zaiman AL, Crow MT, Deng H, Wadgaonkar R, Romer LH, Garcia JG. 2003a. Caspase-dependent cleavage of myosin light chain kinase (MLCK) is involved in TNF-alpha-mediated bovine pulmonary endothelial cell apoptosis. FASEB J 17:407-416.
24. Petrache I, Crow MT, Neuss M, Garcia JG. 2003b. Central involvement of Rho family GTPases in TNF-alpha-mediated bovine pulmonary endothelial cell apoptosis. Biochem Biophys Res Commun 306:244-249.
25. Ponsaerts R, D'Hondt C, Bultynck G, Srinivas SP, Vereecke J, Himpens B. 2008. The myosin II ATPase inhibitor blebbistatin prevents thrombin-induced inhibition of intercellular calcium wave propagation in corneal endothelial cells. Invest Ophthalmol Vis Sci 49:4816-4827.
26. Rey M, Valenzuela-Fernandez A, Urzainqui A, Yanez-Mo M, Perez-Martinez M, Penela P, Mayor F, Jr., Sanchez-Madrid F. 2007. Myosin IIA is involved in the endocytosis of CXCR4 induced by SDF-1alpha. J Cell Sci 120:1126-1133.
27. Rodier F, Bertrand R, Bossolasco M, Mes-Masson AM. 2000. Polyomavirus large T-antigen protects mouse cells from Fas-, TNF-alpha- and taxol-induced apoptosis. Oncogene 19:6261-6270.
28. Samaniego R, Sanchez-Martin L, Estecha A, Sanchez-Mateos P. 2007. Rho/ ROCK and myosin II control the polarized distribution of endocytic clathrin structures at the uropod of moving T lymphocytes. J Cell Sci 120:3534-3543.
29. Sandquist JC, Swenson KI, Demali KA, Burridge K, Means AR. 2006. Rho kinase differentially regulates phosphorylation of nonmuscle myosin II isoforms A and B during cell rounding and migration. J Biol Chem 281: 35873-35883.
30. Schliwa M. 1982. Action of cytochalasin D on cytoskeletal networks. J Cell Biol 92:79-91.
31. Schneider-Brachert W, Tchikov V, Neumeyer J, Jakob M, Winoto-Morbach S, Held-Feindt J, Heinrich M, Merkel O, Ehrenschwender M, Adam D, Mentlein R, Kabelitz D, Schutze S. 2004. Compartmentalization of TNF receptor 1 signaling: Internalized TNF receptosomes as death signaling vesicles. Immunity 21:415-428.
32. Schneider-Brachert W, Tchikov V, Merkel O, Jakob M, Hallas C, Kruse ML, Groitl P, Lehn A, Hildt E, Held-Feindt J, Dobner T, Kabelitz D, Kronke M, Schutze S. 2006. Inhibition of TNF receptor 1 internalization by adenovirus 14.7K as a novel immune escape mechanism. J Clin Invest 116:2901-2913.
33. Schutze S, Machleidt T, Adam D, Schwandner R, Wiegmann K, Kruse ML, Heinrich M, Wickel M, Kronke M. 1999. Inhibition of receptor internalization by monodansylcadaverine selectively blocks p55 tumor necrosis factor receptor death domain signaling. J Biol Chem 274:10203-10212.
34. Sellers JR, Knight PJ. 2007. Folding and regulation in myosins II and V. J Muscle Res Cell Motil 28:363-370.
35. Tartaglia LA, Ayres TM, Wong GH, Goeddel DV. 1993. A novel domain within the 55 kd TNF receptor signals cell death. Cell 74:845-853.
36. Tracey D, Klareskog L, Sasso EH, Salfeld JG, Tak PP. 2008. Tumor necrosis factor antagonist mechanisms of action: A comprehensive review. Pharmacol Ther 117:244-279.
37. Tyska MJ, Warshaw DM. 2002. The myosin power stroke. Cell Motil Cytoskeleton 51:1-15.
38. Ungewickell EJ, Hinrichsen L. 2007. Endocytosis: Clathrin-mediated membrane budding. Curr Opin Cell Biol 19:417-425.
39. Vicente-Manzanares M, Koach MA, Whitmore L, Lamers ML, Horwitz AF. 2008. Segregation and activation of myosin IIB creates a rear in migrating cells. J Cell Biol 183:543-554.
40. Vicente-Manzanares M, Ma X, Adelstein RS, Horwitz AR. 2009. Non-muscle myosin II takes centre stage in cell adhesion and migration. Nat Rev Mol Cell Biol 10:778-790.
41. Wadgaonkar R, Linz-McGillem L, Zaiman AL, Garcia JG. 2005. Endothelial cell myosin light chain kinase (MLCK) regulates TNFalpha-induced NFkappaB activity. J Cell Biochem 94:351-364.
42. Zang JH, Spudich JA. 1998. Myosin II localization during cytokinesis occurs by a mechanism that does not require its motor domain. Proc Natl Acad Sci USA 95:13652-13657.