IGF-1 induces iNOS expression via the p38 MAPK signal pathway in the anti-apoptotic process in pulmonary artery smooth muscle cells during PAH

Journal of Receptors and Signal Transduction

Volumn 34, Issue 4, 2014, Pages 325-331

  Jin, Chengtao ^a   Qiu, Xiaoming ^b   Ma, Ke ^a   Xiang, Mufen ^a   Zhu, Xiaobin ^a   Guo, Jige ^a  

^a Department of Pharmacy ^*  (United States)

^b ZHEJIANG UNIVERSITY   (China)

Author keywords

Apoptosis; IGF 1; INOS; P38 MAPK; PASMC

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE P38; SOMATOMEDIN C;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; NONHUMAN; PROTEIN EXPRESSION; PULMONARY ARTERY; PULMONARY HYPERTENSION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; HYPERTENSION; METABOLISM; PATHOLOGY;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HUMANS; HYPERTENSION; INSULIN-LIKE GROWTH FACTOR I; MYOCYTES, SMOOTH MUSCLE; NITRIC OXIDE SYNTHASE TYPE II; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PULMONARY ARTERY; RATS; SIGNAL TRANSDUCTION;

EID: 84905168844     PISSN: 10799893     EISSN: 15324281     Source Type: Journal    
DOI: 10.3109/10799893.2014.903417     Document Type: Article

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