Genome-wide pathway analysis in attention-deficit/hyperactivity disorder

Neurological Sciences

Volumn 35, Issue 8, 2014, Pages 1189-1196

  Lee, Young Ho ^a   Song, Gwan Gyu ^a  

^a Korea University College of Medicine   (South Korea)

Author keywords

Attention deficit hyperactivity disorder; Genome wide association study; Pathway based analysis

Indexed keywords

ADENOSINE TRIPHOSPHATE CITRATE LYASE; ATM PROTEIN; CASPASE 9; CD12ORF65 PROTEIN; CD27 ANTIGEN; OXOEICOSANOID RECEPTOR 1; PROTEIN; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATE CITRATE SYNTHASE; ATM PROTEIN, HUMAN; C12ORF65 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; MITOCHONDRIAL PROTEIN; OXER1 PROTEIN, HUMAN; RECEPTOR; TRANSLATION TERMINATION FACTOR;

ADOLESCENT; ARTICLE; ATTENTION DEFICIT DISORDER; CHILD; DISEASE PREDISPOSITION; GENE EXPRESSION; GENE IDENTIFICATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC REGULATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; META ANALYSIS (TOPIC); MITOCHONDRIAL GENE; NUCLEOCYTOPLASMIC TRANSPORT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; BIOLOGICAL MODEL; EPIDEMIOLOGY; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC PREDISPOSITION; GENETICS; MALE; METABOLISM; PHYSIOLOGY;

ADOLESCENT; ANTIGENS, CD27; ATAXIA TELANGIECTASIA MUTATED PROTEINS; ATP CITRATE (PRO-S)-LYASE; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CASPASE 9; CAUSALITY; CHILD; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; METABOLIC NETWORKS AND PATHWAYS; MITOCHONDRIAL PROTEINS; MODELS, GENETIC; PEPTIDE TERMINATION FACTORS; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, EICOSANOID;

EID: 84905091266     PISSN: 15901874     EISSN: 15903478     Source Type: Journal    
DOI: 10.1007/s10072-014-1671-2     Document Type: Article

References (19)

1. Franke B, Faraone SV, Asherson P, Buitelaar J, Bau CH, Ramos-Quiroga JA, Mick E, Grevet EH, Johansson S, Haavik J, Lesch KP, Cormand B, Reif A, International Multicentre Persistent ADHD Collaboration (2012) The genetics of attention deficit/hyperactivity disorder in adults, a review. Mol Psychiatry 17:960-987
2. Manolio TA (2010) Genomewide association studies and assessment of the risk of disease. N Engl J Med 363:166-176
3. Choi SJ, Rho YH, Ji JD, Song GG, Lee YH (2006) Genome scan meta-analysis of rheumatoid arthritis. Rheumatology (Oxford) 45:166-170 (Pubitemid 43160077)
4. Lee YH, Nath SK (2005) Systemic lupus erythematosus susceptibility loci defined by genome scan meta-analysis. Hum Genet 118:434-443 (Pubitemid 43091214)
5. Johnson AD, O'Donnell CJ (2009) An open access database of genome-wide association results. BMC Med Genet 10:6
6. Boomsma DI, Willemsen G, Sullivan PF, Heutink P, Meijer P, Sondervan D, Kluft C, Smit G, Nolen WA, Zitman FG, Smit JH, Hoogendijk WJ, van Dyck R, de Geus EJ, Penninx BW (2008) Genome-wide association of major depression: description of samples for the GAIN Major Depressive Disorder Study: NTR and NESDA biobank projects. Eur J Hum Genet 16:335-342 (Pubitemid 351292233)
7. Wang K, Li M, Hakonarson H (2010) Analysing biological pathways in genome-wide association studies. Nat Rev Genet 11:843-854
8. Lee YH, Song GG (2012) Pathway analysis of genome-wide association studies on uric acid concentrations. Hum Immunol 73:805-810
9. Zhang K, Chang S, Cui S, Guo L, Zhang L, Wang J (2011) ICSNPathway: identify candidate causal SNPs and pathways from genome-wide association study by one analytical framework. Nucleic Acids Res 39:W437-W443
10. Kuntsi J, Neale BM, Chen W, Faraone SV, Asherson P (2006) The IMAGE project: methodological issues for the molecular genetic analysis of ADHD. Behav Brain Funct 2:27
11. Coghill D, Banaschewski T (2009) The genetics of attentiondeficit/ hyperactivity disorder. Expert Rev Neurother 9:1547-1565
12. Croft M (2009) The role of TNF superfamily members in T-cell function and diseases. Nat Rev Immunol 9:271-285
13. Wurstle ML, Laussmann MA, Rehm M (2012) The central role of initiator caspase-9 in apoptosis signal transduction and the regulation of its activation and activity on the apoptosome. Exp Cell Res 318:1213-1220
14. Carlessi L, Fusar Poli E, De Filippis L, Delia D (2013) ATM-deficient human neural stem cells as an in vitro model system to study neurodegeneration. DNA Repair (Amst) 12(8): 605-611
15. Duarte I, Nabuurs SB, Magno R, Huynen M (2012) Evolution and diversification of the organellar release factor family. Mol Biol Evol 29:3497-3512
16. Dantzer R, O'Connor JC, Freund GG, Johnson RW, Kelley KW (2008) From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci 9:46-56 (Pubitemid 350295688)
17. Pardo CA, Vargas DL, Zimmerman AW (2005) Immunity, neuroglia and neuroinflammation in autism. Int Rev Psychiatry 17:485-495 (Pubitemid 43086675)
18. Balestrieri E, Pitzianti M, Matteucci C, D'Agati E, Sorrentino R, Baratta A, Caterina R, Zenobi R, Curatolo P, Garaci E, Sinibaldi-Vallebona P, Pasini A (2013) Human endogenous retroviruses and ADHD. World J Biol Psychiatry. doi:10.3109/15622975.2013.862345
19. Mann JR, McDermott S (2011) Are maternal genitourinary infection and pre-eclampsia associated with ADHD in school-aged children? J Atten Disord 15:667-673