On the horizon: Research priorities in burns for the next decade

Surgical Clinics of North America

Volumn 94, Issue 4, 2014, Pages 917-930

  Wolf, Steven E ^a   Tompkins, Ronald G ^b   Herndon, David N ^c  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Burn care; Inflammation; Pain; Scarring

Indexed keywords

BURN; DEPRESSION; HEALING; HUMAN; HYPERMETABOLISM; INFLAMMATION; INTENSIVE CARE; MENTAL HEALTH; PAIN; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; RESEARCH PRIORITY; REVIEW; SCAR; WOUND HEALING;

BURN CARE; INFLAMMATION; PAIN; SCARRING;

BURNS; CICATRIX; FORECASTING; HUMANS; INFLAMMATION; MENTAL DISORDERS; METABOLIC DISEASES; PAIN; PATIENT OUTCOME ASSESSMENT; RESEARCH; WOUND HEALING;

EID: 84905052367     PISSN: 00396109     EISSN: 15583171     Source Type: Journal    
DOI: 10.1016/j.suc.2014.05.012     Document Type: Review

References (71)

1. Geomelas M., Ghods M., Ring A., et al. "The Maestro": a pioneering plastic surgeon-Sir Archibald McIndoe and his innovating work on patients with burn injury during World War II. J Burn Care Res 2011, 32(3):363-368.
2. Barillo D.J., Wolf S. Planning for burn disasters: lessons learned from one hundred years of history. J Burn Care Res 2006, 27(5):622-634.
3. Pruitt B.A., Wolf S.E. An historical perspective on advances in burn care over the past 100 years. Clin Plast Surg 2009, 36(4):527-545.
4. Janzekovic Z. A new concept in the early excision and immediate grafting of burns. J Trauma 1970, 10(12):1103-1108.
5. Herndon D.N., Parks D.H. Comparison of serial debridement and autografting and early massive excision with cadaver skin overlay in the treatment of large burns in children. J Trauma 1986, 26(2):149-152.
6. Al-Mousawi A.M., Mecott-Rivera G.A., Jeschke M.G., et al. Burn teams and burn centers: the importance of a comprehensive team approach to burn care. Clin Plast Surg 2009, 36(4):547-554.
7. Kraft R., Herndon D.N., Al-Mousawi A.M., et al. Burn size and survival probability in paediatric patients in modern burn care: a prospective observational cohort study. Lancet 2012, 379(9820):1013-1021.
8. Xiao W., Mindrinos M.N., Seok J., et al. A genomic storm in critically injured humans. J Exp Med 2011, 208(13):2581-2590.
9. Pruitt B.A. The universal trauma model. Bull Am Coll Surg 1985, 70:2-13.
10. Finnerty C.C., Ju H., Spratt H., et al. Proteomics improves the prediction of burns mortality: results from regression spline modeling. Clin Transl Sci 2012, 5(3):243-249.
11. Seok J., Warren H.S., Cuenca A.G., et al. Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci U S A 2013, 110(9):3507-3512.
12. Herndon D.N., Hart D.W., Wolf S.E., et al. Reversal of catabolism by beta-blockade after severe burns. N Engl J Med 2001, 345(17):1223-1229.
13. Wolf S.E., Edelman L.S., Kemalyan N., et al. Effects of oxandrolone on outcome measures in the severely burned: a multicenter prospective randomized double-blind trial. J Burn Care Res 2006, 27(2):131-139. [discussion: 140-1].
14. Wolf S.E., Thomas S.J., Dasu M.R., et al. Improved net protein balance, lean mass, and gene expression changes with oxandrolone treatment in the severely burned. Ann Surg 2003, 237(6):801-810. [discussion: 810-1].
15. Thomas S.J., Morimoto K., Herndon D.N., et al. The effect of prolonged euglycemic hyperinsulinemia on lean body mass after severe burn. Surgery 2002, 132(2):341-347.
16. Mann E.A., Wood G.L., Wade C.E. Use of procalcitonin for the detection of sepsis in the critically ill burn patient: a systematic review of the literature. Burns 2011, 37(4):549-558.
17. Yavuz S., Anarat A., Acarturk S., et al. Neutrophil gelatinase associated lipocalin as an indicator of acute kidney injury and inflammation in burned children. Burns 2014, 40(4):648-654.
18. Salinas J., Chung K.K., Mann E.A., et al. Computerized decision support system improves fluid resuscitation following severe burns: an original study. Crit Care Med 2011, 39(9):2031-2038.
19. Mann E.A., Jones J.A., Wolf S.E., et al. Computer decision support software safely improves glycemic control in the burn intensive care unit: a randomized controlled clinical study. J Burn Care Res 2011, 32(2):246-255.
20. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med 2000, 342(18):1301-1308.
21. Schwacha M.G. Opiates and the development of post-injury complications: a review. Int J Clin Exp Med 2008, 1(1):42-49.
22. Alexander M., Daniel T., Chaudry I.H., et al. Opiate analgesics contribute to the development of post-injury immunosuppression. J Surg Res 2005, 129(1):161-168.
23. Barajas-Nava L.A., Lopez-Alcalde J., Roque i Figuls M., et al. Antibiotic prophylaxis for preventing burn wound infection. Cochrane Database Syst Rev 2013, (6). CD008738.
24. Sheridan R.L., Tompkins R.G., Burke J.F. Management of burn wounds with prompt excision and immediate closure. J Intensive Care Med 1994, 9(1):6-17.
25. Xiao-Wu W., Herndon D.N., Spies M., et al. Effects of delayed wound excision and grafting in severely burned children. Arch Surg 2002, 137(9):1049-1054.
26. Herndon D.N., Hawkins H.K., Nguyen T.T., et al. Characterization of growth hormone enhanced donor site healing in patients with large cutaneous burns. Ann Surg 1995, 221(6):649-656. [discussion: 656-9].
27. Ramirez R.J., Wolf S.E., Herndon D.N. Is there a role for growth hormone in the clinical management of burn injuries?. Growth Horm IGF Res 1998, 8(Suppl B):99-105.
28. Wood F., Martin L., Lewis D., et al. A prospective randomised clinical pilot study to compare the effectiveness of Biobrane(R) synthetic wound dressing, with or without autologous cell suspension, to the local standard treatment regimen in paediatric scald injuries. Burns 2012, 38(6):830-839.
29. Wood F.M., Giles N., Stevenson A., et al. Characterisation of the cell suspension harvested from the dermal epidermal junction using a ReCell(R) kit. Burns 2012, 38(1):44-51.
30. Wood F.M., Stoner M.L., Fowler B.V., et al. The use of a non-cultured autologous cell suspension and Integra dermal regeneration template to repair full-thickness skin wounds in a porcine model: a one-step process. Burns 2007, 33(6):693-700.
31. Gravante G., Di Fede M.C., Araco A., et al. A randomized trial comparing ReCell system of epidermal cells delivery versus classic skin grafts for the treatment of deep partial thickness burns. Burns 2007, 33(8):966-972.
32. Burke J.F., Yannas I.V., Quinby W.C., et al. Successful use of a physiologically acceptable artificial skin in the treatment of extensive burn injury. Ann Surg 1981, 194(4):413-428.
33. Heimbach D.M., Warden G.D., Luterman A., et al. Multicenter postapproval clinical trial of Integra dermal regeneration template for burn treatment. J Burn Care Rehabil 2003, 24(1):42-48.
34. Heimbach D., Luterman A., Burke J., et al. Artificial dermis for major burns. A multi-center randomized clinical trial. Ann Surg 1988, 208(3):313-320.
35. Ryan C.M., Schoenfeld D.A., Malloy M., et al. Use of Integra artificial skin is associated with decreased length of stay for severely injured adult burn survivors. J Burn Care Rehabil 2002, 23(5):311-317.
36. Covington D.S., Wainwright D.J., Parks D.H. Prognostic indicators in the elderly patient with burns. J Burn Care Rehabil 1996, 17(3):222-230.
37. Branski L.K., Herndon D.N., Pereira C., et al. Longitudinal assessment of Integra in primary burn management: a randomized pediatric clinical trial. Crit Care Med 2007, 35(11):2615-2623.
38. Engrav L.H., Heimbach D.M., Rivara F.P., et al. 12-Year within-wound study of the effectiveness of custom pressure garment therapy. Burns 2010, 36(7):975-983.
39. Ahn S.T., Monafo W.W., Mustoe T.A. Topical silicone gel: a new treatment for hypertrophic scars. Surgery 1989, 106(4):781-786. [discussion: 786-7].
40. Anzarut A., Olson J., Singh P., et al. The effectiveness of pressure garment therapy for the prevention of abnormal scarring after burn injury: a meta-analysis. J Plast Reconstr Aesthet Surg 2009, 62(1):77-84.
41. Taheri A., Mansoori P., Al-Dabagh A., et al. Are corticosteroids effective for prevention of scar formation after second-degree skin burn?. J Dermatolog Treat 2014, 25(4):360-362.
42. Ahuja R.B., Chatterjee P. Comparative efficacy of intralesional verapamil hydrochloride and triamcinolone acetonide in hypertrophic scars and keloids. Burns 2014, 40(4):583-588.
43. Wang X.Q., Liu Y.K., Qing C., et al. A review of the effectiveness of antimitotic drug injections for hypertrophic scars and keloids. Ann Plast Surg 2009, 63(6):688-692.
44. Waibel J., Beer K. Ablative fractional laser resurfacing for the treatment of a third-degree burn. J Drugs Dermatol 2009, 8(3):294-297.
45. Qu L., Liu A., Zhou L., et al. Clinical and molecular effects on mature burn scars after treatment with a fractional CO(2) laser. Lasers Surg Med 2012, 44(7):517-524.
46. Arno A.I., Gauglitz G.G., Barret J.P., et al. New molecular medicine-based scar management strategies. Burns 2014, 40(4):539-551.
47. Hoffman H.G., Chambers G.T., Meyer W.J., et al. Virtual reality as an adjunctive non-pharmacologic analgesic for acute burn pain during medical procedures. Ann Behav Med 2011, 41(2):183-191.
48. Miller K., Rodger S., Kipping B., et al. A novel technology approach to pain management in children with burns: a prospective randomized controlled trial. Burns 2011, 37(3):395-405.
49. Green D.P., Ruparel S., Roman L., et al. Role of endogenous TRPV1 agonists in a postburn pain model of partial-thickness injury. Pain 2013, 154(11):2512-2520.
50. Malenfant A., Forget R., Papillon J., et al. Prevalence and characteristics of chronic sensory problems in burn patients. Pain 1996, 67(2-3):493-500.
51. Schneider J.C., Harris N.L., El Shami A., et al. A descriptive review of neuropathic-like pain after burn injury. J Burn Care Res 2006, 27(4):524-528.
52. Gray P., Kirby J., Smith M.T., et al. Pregabalin in severe burn injury pain: a double-blind, randomised placebo-controlled trial. Pain 2011, 152(6):1279-1288.
53. Gray P., Williams B., Cramond T. Successful use of gabapentin in acute pain management following burn injury: a case series. Pain Med 2008, 9(3):371-376.
54. Altier N., Dion D., Boulanger A., et al. Successful use of methadone in the treatment of chronic neuropathic pain arising from burn injuries: a case-study. Burns 2001, 27(7):771-775.
55. Correa-Illanes G., Calderon W., Roa R., et al. Treatment of localized post-traumatic neuropathic pain in scars with 5% lidocaine medicated plaster. Local Reg Anesth 2010, 3:77-83.
56. Thompson C.D., Uhelski M.L., Wilson J.R., et al. Hyperbaric oxygen treatment decreases pain in two nerve injury models. Neurosci Res 2010, 66(3):279-283.
57. Goutos I. Neuropathic mechanisms in the pathophysiology of burns pruritus: redefining directions for therapy and research. J Burn Care Res 2013, 34(1):82-93.
58. Okhovatian F., Zoubine N. A comparison between two burn rehabilitation protocols. Burns 2007, 33(4):429-434.
59. Tompkins R.G., Liang M.H., Lee A.F., Multi-Center Benchmarking Study Working Group, et al. The American Burn Association/Shriners Hospitals for Children Burn Outcomes Program: a progress report at 15 years. J Trauma Acute Care Surg 2012, 73(3 Suppl 2):S173-S178.
60. Esselman P.C., Thombs B.D., Magyar-Russell G., et al. Burn rehabilitation: state of the science. Am J Phys Med Rehabil 2006, 85(4):383-413.
61. Sveen J., Ekselius L., Gerdin B., et al. A prospective longitudinal study of posttraumatic stress disorder symptom trajectories after burn injury. J Trauma 2011, 71(6):1808-1815.
62. Van Loey N.E., van de Schoot R., Faber A.W. Posttraumatic stress symptoms after exposure to two fire disasters: comparative study. PLoS One 2012, 7(7):e41532.
63. Farroha A., McGregor J., Paget T., et al. Using anonymized, routinely collected health data in Wales to estimate the incidence of depression after burn injury. J Burn Care Res 2013, 34(6):644-648.
64. Hoogewerf C.J., van Baar M.E., Middelkoop E., et al. Impact of facial burns: relationship between depressive symptoms, self-esteem and scar severity. Gen Hosp Psychiatry 2014, 36(3):271-276.
65. Ter Smitten M.H., de Graaf R., Van Loey N.E. Prevalence and co-morbidity of psychiatric disorders 1-4 years after burn. Burns 2011, 37(5):753-761.
66. Morris L.D., Louw Q.A., Crous L.C. Feasibility and potential effect of a low-cost virtual reality system on reducing pain and anxiety in adult burn injury patients during physiotherapy in a developing country. Burns 2010, 36(5):659-664.
67. Morris L.D., Louw Q.A., Grimmer-Somers K. The effectiveness of virtual reality on reducing pain and anxiety in burn injury patients: a systematic review. Clin J Pain 2009, 25(9):815-826.
68. Palmu R., Suominen K., Vuola J., et al. Psychiatric consultation and care after acute burn injury: a 6-month naturalistic prospective study. Gen Hosp Psychiatry 2011, 33(1):16-22.
69. Van Loey N.E., Van de Schoot R., Gerdin B., et al. The Burn Specific Health Scale-Brief: measurement invariant across European countries. J Trauma Acute Care Surg 2013, 74(5):1321-1326.
70. Dyster-Aas J., Willebrand M., Wikehult B., et al. Major depression and posttraumatic stress disorder symptoms following severe burn injury in relation to lifetime psychiatric morbidity. J Trauma 2008, 64(5):1349-1356.
71. Stoddard Jr. F.J., Luthra R., Sorrentino E.A., et al. A randomized controlled trial of sertraline to prevent posttraumatic stress disorder in burned children. J Child Adolesc Psychopharmacol 2011, 21(5):469-477.