Molecular and virological evidence of viral activation from chromosomally integrated human herpesvirus 6A in a patient with X-linked severe combined immunodeficiency

Clinical Infectious Diseases

Volumn 59, Issue 4, 2014, Pages 545-548

  Endo, Akifumi ^a,b   Watanabe, Ken ^a   Ohye, Tamae ^c   Suzuki, Kyoko ^d   Matsubara, Tomoyo ^d   Shimizu, Norio ^a   Kurahashi, Hiroki ^c   Yoshikawa, Tetsushi ^c   Katano, Harutaka ^e   Inoue, Naoki ^e   Imai, Kohsuke ^a   Takagi, Masatoshi ^a   Morio, Tomohiro ^a   Mizutani, Shuki ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b Komagome Hospital   (Japan)

^c FUJITA HEALTH UNIVERSITY   (Japan)

^d JUNTENDO UNIVERSITY URAYASU HOSPITAL   (Japan)

^e NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

CiHHV 6; Hemophagocytic Syndrome; HHV 6; Thrombotic microangiopathy; X SCID

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; FERRITIN; FOSCARNET; GANCICLOVIR; HEMOGLOBIN; IMMUNOGLOBULIN; INTERLEUKIN 2 RECEPTOR GAMMA; PREDNISOLONE; TACROLIMUS; VIRUS DNA; VIRUS RNA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANTICOAGULANT THERAPY; ANTIVIRAL THERAPY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BONE MARROW BIOPSY; CASE REPORT; CHILD HOSPITALIZATION; CHROMOSOME 22; COUGHING; DIARRHEA; DRUG DOSE REDUCTION; ENGRAFTMENT; FAILURE TO THRIVE; FEVER; FIBROBLAST; FINGER NAIL; FLUORESCENCE IN SITU HYBRIDIZATION; GASTROINTESTINAL HEMORRHAGE; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GENOME; HAIR FOLLICLE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMOGLOBIN BLOOD LEVEL; HEMOPHAGOCYTIC SYNDROME; HERPES VIRUS INFECTION; HETEROZYGOTE; HUMAN; HUMAN HERPESVIRUS 6; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; INFANT; LEUKOCYTE COUNT; MALE; PANCYTOPENIA; PERIPHERAL BLOOD MONONUCLEAR CELL; PHAGOCYTE; PHYLOGENY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; T LYMPHOCYTE; THROMBOCYTE COUNT; THROMBOTIC THROMBOCYTOPENIC PURPURA; UMBILICAL CORD BLOOD; VIRUS ACTIVATION; VIRUS GENE; VIRUS ISOLATION; VIRUS LOAD; VIRUS STRAIN; X LINKED SEVERE COMBINED IMMUNODEFICIENCY; BONE MARROW; COMPLICATION; CYTOCHEMISTRY; GENETICS; ISOLATION AND PURIFICATION; MICROSCOPY; MONONUCLEAR CELL; PATHOLOGY; PHYSIOLOGY; ROSEOLOVIRUS INFECTIONS; VIROLOGY;

BONE MARROW; CHROMOSOMES, HUMAN, PAIR 22; DNA, VIRAL; FIBROBLASTS; HERPESVIRUS 6, HUMAN; HISTOCYTOCHEMISTRY; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; INFANT; LEUKOCYTES, MONONUCLEAR; MALE; MICROSCOPY; ROSEOLOVIRUS INFECTIONS; VIRUS ACTIVATION; X-LINKED COMBINED IMMUNODEFICIENCY DISEASES;

EID: 84905043671     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/ciu323     Document Type: Article

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