Studying tumorigenesis through network evolution and somatic mutational perturbations in the cancer interactome

Molecular Biology and Evolution

Volumn 31, Issue 8, 2014, Pages 2156-2169

  Cheng, Feixiong ^a   Jia, Peilin ^a   Wang, Quan ^a   Lin, Chen Ching ^a   Li, Wen Hsiung ^b,c   Zhao, Zhongming ^a,d  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c BIODIVERSITY RESEARCH CENTER   (Taiwan)

^d VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

network evolution; network attacking perturbation; somatic mutation; TCGA; tumorigenesis

Indexed keywords

TUMOR PROTEIN;

ARTICLE; CARCINOGENESIS; CELL DIFFERENTIATION; CORRELATION ANALYSIS; EVOLUTIONARY RATE; GENE; GENE LOCATION; GENE MUTATION; GENETIC DATABASE; GENETIC SELECTION; GERMLINE MUTATION; HUMAN; MALIGNANT TRANSFORMATION; MENDELIAN DISEASE GENE; MOLECULAR EVOLUTION; MOLECULAR PHYLOGENY; ORPHAN DISEASE CAUSING MUTANT GENE; PROTEIN PROTEIN INTERACTION; SOMATIC MUTATION; TUMOR GENE; BIOLOGICAL MODEL; BIOLOGY; ESSENTIAL GENE; GENE REGULATORY NETWORK; GENETICS; MUTATION; PROCEDURES; PROTEIN ANALYSIS;

CARCINOGENESIS; COMPUTATIONAL BIOLOGY; DATABASES, GENETIC; GENE REGULATORY NETWORKS; GENES, ESSENTIAL; HUMANS; MODELS, GENETIC; MUTATION; PROTEIN INTERACTION MAPPING; SELECTION, GENETIC;

EID: 84905039882     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msu167     Document Type: Article

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