Testosterone rapidly increases neural reactivity to threat in healthy men: A novel two-step pharmacological challenge paradigm

Biological Psychiatry

Volumn 76, Issue 4, 2014, Pages 324-331

  Goetz, Stefan M M ^a   Tang, Lingfei ^a   Thomason, Moriah E ^a,b   Diamond, Michael P ^c   Hariri, Ahmad R ^a,d   Carré, Justin M ^a,e  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

^d DUKE UNIVERSITY   (United States)

^e NIPISSING UNIVERSITY   (Canada)

Author keywords

Aggression; amygdala; androgens; anger; emotion; fMRI; testosterone

Indexed keywords

GONADORELIN; GONADORELIN ANTAGONIST; TESTOSTERONE; HORMONE ANTAGONIST; OXYGEN;

ADULT; AGGRESSION; AMYGDALOID NUCLEUS; ANGER; ARTICLE; BASOLATERAL AMYGDALA; BOLD SIGNAL; BRAIN FUNCTION; CONTROLLED STUDY; EMOTION; FACIAL EXPRESSION; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; HORMONE RESPONSE; HUMAN; HUMAN EXPERIMENT; HYPOTHALAMUS; MALE; NERVE POTENTIAL; NORMAL HUMAN; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; RESPONSE TIME; TESTOSTERONE BLOOD LEVEL; THREAT; ADOLESCENT; ANTAGONISTS AND INHIBITORS; BLOOD; BLOOD ANALYSIS; BRAIN; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFECTS; METABOLISM; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; PHOTOSTIMULATION; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; SIGNAL PROCESSING; VISION; YOUNG ADULT;

ADOLESCENT; ADULT; AGGRESSION; BLOOD CHEMICAL ANALYSIS; BRAIN; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FACIAL EXPRESSION; GONADOTROPIN-RELEASING HORMONE; HORMONE ANTAGONISTS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NEUROPSYCHOLOGICAL TESTS; OXYGEN; PHOTIC STIMULATION; SIGNAL PROCESSING, COMPUTER-ASSISTED; TESTOSTERONE; VISUAL PERCEPTION; YOUNG ADULT;

EID: 84905038164     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2014.01.016     Document Type: Article

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