Afatinib and its encapsulated polymeric micelles inhibits HER2-overexpressed colorectal tumor cell growth in vitro and in vivo

Oncotarget

Volumn 5, Issue 13, 2014, Pages 4868-4880

  Guan, Siao Syun ^a,b   Chang, Jungshan ^c   Cheng, Chun Chia ^b,c   Luo, Tsai Yueh ^b   Ho, Ai Sheng ^d   Wang, Chia Chi ^e   Wu, Cheng Tien ^a   Liu, Shing Hwa ^a,f,g  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b INSTITUTE OF NUCLEAR ENERGY RESEARCH   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d CHENG HSIN GENERAL HOSPITAL   (Taiwan)

^e TZU CHI UNIVERSITY   (Taiwan)

^f CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^g NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Afatinib; Colorectal cancer; HER2; Micelles

Indexed keywords

AFATINIB; EPIDERMAL GROWTH FACTOR RECEPTOR 2; POLYMER; MICELLE; QUINAZOLINE DERIVATIVE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CLINICAL ARTICLE; COLORECTAL CANCER; COLORECTAL CANCER CELL LINE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; ENCAPSULATION; FEMALE; GASTRIC CANCER CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MALE; MICELLE; MOUSE; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; TUMOR XENOGRAFT; AGED; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; BLOOD; CELL PROLIFERATION; CELL SURVIVAL; CHEMISTRY; COLORECTAL NEOPLASMS; DRUG EFFECTS; DRUG FORMULATION; DRUG SCREENING; HEPG2 CELL LINE; IMMUNOBLOTTING; MCF 7 CELL LINE; METABOLISM; MIDDLE AGED; NUDE MOUSE; PATHOLOGY; TUMOR CELL LINE; TUMOR VOLUME;

ADULT; AGED; ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; COLORECTAL NEOPLASMS; DRUG COMPOUNDING; FEMALE; HEP G2 CELLS; HUMANS; IMMUNOBLOTTING; MALE; MCF-7 CELLS; MICE, INBRED BALB C; MICE, NUDE; MICELLES; MIDDLE AGED; POLYMERS; QUINAZOLINES; RECEPTOR, ERBB-2; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84904977776     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2050     Document Type: Article

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