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Volumn 4, Issue , 2014, Pages

Lycium barbarum polysaccharides therapeutically improve hepatic functions in non-alcoholic steatohepatitis rats and cellular steatosis model

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOBESITY AGENT; ARABINOSE; BETA CAROTENE; HERBACEOUS AGENT; LYCIUM BARBARUM POLYSACCHARIDE;

EID: 84904962594     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep05587     Document Type: Article
Times cited : (108)

References (44)
  • 3
    • 84878613524 scopus 로고    scopus 로고
    • Review article: Is non-alcoholic fatty liver disease a spectrum, or are steatosis and non-alcoholic steatohepatitis distinct conditions?
    • Yilmaz, Y. Review article: is non-alcoholic fatty liver disease a spectrum, or are steatosis and non-alcoholic steatohepatitis distinct conditions? Aliment. Pharmacol. Ther. 36, 815-823 (2012).
    • (2012) Aliment. Pharmacol. Ther. , vol.36 , pp. 815-823
    • Yilmaz, Y.1
  • 4
    • 84879273144 scopus 로고    scopus 로고
    • Therapeutic approaches to non-alcoholic fatty liver disease: Past achievements and future challenges
    • Xiao, J., Guo, R., Fung, M. L., Liong, E. C.&Tipoe, G. L. Therapeutic approaches to non-alcoholic fatty liver disease: past achievements and future challenges. Hepatobiliary Pancreat. Dis. Int. 12, 125-135 (2013).
    • (2013) Hepatobiliary Pancreat. Dis. Int. , vol.12 , pp. 125-135
    • Xiao, J.1    Guo, R.2    Fung, M.L.3    Liong, E.C.4    Tipoe, G.L.5
  • 5
    • 78049516031 scopus 로고    scopus 로고
    • Coffee reduces liver damage in a rat model of steatohepatitis: The underlying mechanisms and the role of polyphenols and melanoidins
    • Vitaglione, P. et al. Coffee reduces liver damage in a rat model of steatohepatitis: the underlying mechanisms and the role of polyphenols and melanoidins. Hepatology. 52, 1652-1661 (2010).
    • (2010) Hepatology. , vol.52 , pp. 1652-1661
    • Vitaglione, P.1
  • 6
    • 84872674658 scopus 로고    scopus 로고
    • Garlic-derived S-allylmercaptocysteine is a hepato-protective agent in non-alcoholic fatty liver disease in vivo animal model
    • Xiao, J. et al. Garlic-derived S-allylmercaptocysteine is a hepato-protective agent in non-alcoholic fatty liver disease in vivo animal model. Eur. J. Nutr. 52, 179-191 (2013).
    • (2013) Eur. J. Nutr. , vol.52 , pp. 179-191
    • Xiao, J.1
  • 7
    • 84880175454 scopus 로고    scopus 로고
    • Garlic-Derived S-Allylmercaptocysteine Ameliorates Nonalcoholic Fatty Liver Disease in a Rat Model through Inhibition of Apoptosis and Enhancing Autophagy
    • Xiao, J. et al. Garlic-Derived S-Allylmercaptocysteine Ameliorates Nonalcoholic Fatty Liver Disease in a Rat Model through Inhibition of Apoptosis and Enhancing Autophagy. Evid. Based Complement. Alternat. Med. 2013, 642920 (2013).
    • (2013) Evid. Based Complement. Alternat. Med. , vol.2013 , pp. 642920
    • Xiao, J.1
  • 8
    • 84895076381 scopus 로고    scopus 로고
    • Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways
    • doi:10.1007/s00394-013-0516-8
    • Xiao, J. et al. Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways. Eur. J. Nutr. doi:10.1007/s00394-013-0516-8 (2013).
    • (2013) Eur. J. Nutr.
    • Xiao, J.1
  • 10
    • 84869238321 scopus 로고    scopus 로고
    • Alleviative effects of resveratrol on nonalcoholic fatty liver disease are associated with up regulation of hepatic low density lipoprotein receptor and scavenger receptor class B type i gene expressions in rats
    • Xin, P. et al. Alleviative effects of resveratrol on nonalcoholic fatty liver disease are associated with up regulation of hepatic low density lipoprotein receptor and scavenger receptor class B type I gene expressions in rats. Food Chem. Toxicol. 52, 12-18 (2013).
    • (2013) Food Chem. Toxicol. , vol.52 , pp. 12-18
    • Xin, P.1
  • 11
    • 46149090121 scopus 로고    scopus 로고
    • Use of anti-aging herbal medicine, Lycium barbarum, against aging-associated diseases. What do we know so far?
    • DOI 10.1007/s10571-007-9181-x
    • Chang, R. C. & So, K. F. Use of anti-aging herbal medicine, Lycium barbarum, against aging-associated diseases. What do we know so far? Cell. Mol. Neurobiol. 28, 643-652 (2008). (Pubitemid 351905068)
    • (2008) Cellular and Molecular Neurobiology , vol.28 , Issue.5 , pp. 643-652
    • Chang, R.C.-C.1    So, K.-F.2
  • 12
    • 13844299309 scopus 로고    scopus 로고
    • Effect of lycium barbarum polysaccharide on human hepatoma QGY7703 cells: Inhibition of proliferation and induction of apoptosis
    • DOI 10.1016/j.lfs.2004.11.009
    • Zhang, M. et al. Effect of lycium barbarum polysaccharide on human hepatoma QGY7703 cells: inhibition of proliferation and induction of apoptosis. Life Sci. 76, 2115-2124 (2005). (Pubitemid 40249369)
    • (2005) Life Sciences , vol.76 , Issue.18 , pp. 2115-2124
    • Zhang, M.1    Chen, H.2    Huang, J.3    Li, Z.4    Zhu, C.5    Zhang, S.6
  • 13
    • 79551517589 scopus 로고    scopus 로고
    • Lycium barbarum polysaccharides reduce neuronal damage, bloodretinal barrier disruption and oxidative stress in retinal ischemia/reperfusion injury
    • Li, S. Y. et al. Lycium barbarum polysaccharides reduce neuronal damage, bloodretinal barrier disruption and oxidative stress in retinal ischemia/reperfusion injury. PloS one 6 (2011).
    • (2011) PloS One , vol.6
    • Li, S.Y.1
  • 14
    • 84856016199 scopus 로고    scopus 로고
    • Lycium barbarum polysaccharides protect mice liver from carbon tetrachloride-induced oxidative stress and necroinflammation
    • Xiao, J. et al. Lycium barbarum polysaccharides protect mice liver from carbon tetrachloride-induced oxidative stress and necroinflammation. J. Ethnopharmacol. 139, 462-470 (2012).
    • (2012) J. Ethnopharmacol. , vol.139 , pp. 462-470
    • Xiao, J.1
  • 15
    • 84883037365 scopus 로고    scopus 로고
    • Lycium barbarum polysaccharides protect rat liver from nonalcoholic steatohepatitis-induced injury
    • Xiao, J. et al. Lycium barbarum polysaccharides protect rat liver from nonalcoholic steatohepatitis-induced injury. Nutr. Diabetes. 3, e81 (2013).
    • (2013) Nutr. Diabetes. , vol.3
    • Xiao, J.1
  • 16
    • 70349779693 scopus 로고    scopus 로고
    • Voluntary oral feeding of rats not requiring a very high fat diet is a clinically relevant animal model of non-alcoholic fatty liver disease (NAFLD)
    • Tipoe, G. L. et al. Voluntary oral feeding of rats not requiring a very high fat diet is a clinically relevant animal model of non-alcoholic fatty liver disease (NAFLD). Histol. Histopathol. 24, 1161-1169 (2009).
    • (2009) Histol. Histopathol. , vol.24 , pp. 1161-1169
    • Tipoe, G.L.1
  • 18
    • 65449161015 scopus 로고    scopus 로고
    • APPL1 potentiates insulin-mediated inhibition of hepatic glucose production and alleviates diabetes via Akt activation in mice
    • Cheng, K. K. et al. APPL1 potentiates insulin-mediated inhibition of hepatic glucose production and alleviates diabetes via Akt activation in mice. Cell Metab. 9, 417-427 (2009).
    • (2009) Cell Metab. , vol.9 , pp. 417-427
    • Cheng, K.K.1
  • 19
    • 70349624987 scopus 로고    scopus 로고
    • NIH experiment in centralized mouse phenotyping: The Vanderbilt experience and recommendations for evaluating glucose homeostasis in the mouse
    • McGuinness, O. P., Ayala, J. E., Laughlin, M. R. & Wasserman, D. H. NIH experiment in centralized mouse phenotyping: the Vanderbilt experience and recommendations for evaluating glucose homeostasis in the mouse. Am. J. Physiol. Endocrinol. Metab. 297, E849-E855 (2009).
    • (2009) Am. J. Physiol. Endocrinol. Metab. , vol.297
    • McGuinness, O.P.1    Ayala, J.E.2    Laughlin, M.R.3    Wasserman, D.H.4
  • 20
    • 79960856005 scopus 로고    scopus 로고
    • The effects of L-arabinose on intestinal sucrase activity: Dose-response studies in vitro and in humans
    • Krog-Mikkelsen, I. et al. The effects of L-arabinose on intestinal sucrase activity: dose-response studies in vitro and in humans. Am. J. Clin. Nutr. 94, 472-478 (2011).
    • (2011) Am. J. Clin. Nutr. , vol.94 , pp. 472-478
    • Krog-Mikkelsen, I.1
  • 21
    • 0029787986 scopus 로고    scopus 로고
    • Carotene and lutein protect HepG2 human liver cells against oxidant- induced damage
    • Martin, K. R., Failla, M. L. & Smith, J. C., Jr. Beta-carotene and lutein protect HepG2 human liver cells against oxidant-induced damage. J. Nutr. 126, 2098-2106 (1996). (Pubitemid 26313586)
    • (1996) Journal of Nutrition , vol.126 , Issue.9 , pp. 2098-2106
    • Martin, K.R.1    Failla, M.L.2    Smith Jr., J.C.3
  • 22
    • 34248597376 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha gene from mandarin fish, Siniperca chuatsi: Molecular cloning, cytotoxicity analysis and expression profile
    • DOI 10.1016/j.molimm.2007.03.016, PII S0161589007001253
    • Xiao, J. et al. Tumor necrosis factor-alpha gene from mandarin fish, Siniperca chuatsi: molecular cloning, cytotoxicity analysis and expression profile. Mol. Immunol. 44, 3615-3622 (2007). (Pubitemid 46754443)
    • (2007) Molecular Immunology , vol.44 , Issue.14 , pp. 3615-3622
    • Xiao, J.1    Zhou, Z.-C.2    Chen, C.3    Huo, W.-L.4    Yin, Z.-X.5    Weng, S.-P.6    Chan, S.-M.7    Yu, X.-Q.8    He, J.-G.9
  • 23
    • 64149097786 scopus 로고    scopus 로고
    • The MIQE guidelines: Minimum information for publication of quantitative real-time PCR experiments
    • Bustin, S. A. et al. The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin. Chem. 55, 611-622 (2009).
    • (2009) Clin. Chem. , vol.55 , pp. 611-622
    • Bustin, S.A.1
  • 24
    • 0032763059 scopus 로고    scopus 로고
    • Synaptophysin: A novel marker for human and rat hepatic stellate cells
    • Cassiman, D. et al. Synaptophysin: A novel marker for human and rat hepatic stellate cells. Am. J. Pathol. 155, 1831-1839 (1999).
    • (1999) Am. J. Pathol. , vol.155 , pp. 1831-1839
    • Cassiman, D.1
  • 26
    • 84884250892 scopus 로고    scopus 로고
    • Silibinin ameliorates steatosis and insulin resistance during nonalcoholic fatty liver disease development partly through targeting IRS-1/PI3K/Akt pathway
    • Zhang, Y. et al. Silibinin ameliorates steatosis and insulin resistance during nonalcoholic fatty liver disease development partly through targeting IRS-1/PI3K/Akt pathway. Int. Immunopharmacol. 17, 714-720 (2013).
    • (2013) Int. Immunopharmacol. , vol.17 , pp. 714-720
    • Zhang, Y.1
  • 27
    • 84864110034 scopus 로고    scopus 로고
    • Management of nonalcoholic steatohepatitis: An evidence-based approach
    • Mahady, S. E. & George, J. Management of nonalcoholic steatohepatitis: an evidence-based approach. Clin. Liver Dis. 16, 631-645 (2012).
    • (2012) Clin. Liver Dis. , vol.16 , pp. 631-645
    • Mahady, S.E.1    George, J.2
  • 28
    • 61349140201 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: The pathogenetic roles of insulin resistance and adipocytokines
    • Polyzos, S. A., Kountouras, J. & Zavos, C. Nonalcoholic fatty liver disease: the pathogenetic roles of insulin resistance and adipocytokines. Curr. Mol. Med. 9, 299-314 (2009).
    • (2009) Curr. Mol. Med. , vol.9 , pp. 299-314
    • Polyzos, S.A.1    Kountouras, J.2    Zavos, C.3
  • 29
    • 33845490856 scopus 로고    scopus 로고
    • Review: The role of insulin resistance in nonalcoholic fatty liver disease
    • DOI 10.1210/jc.2006-0587
    • Utzschneider, K. M. & Kahn, S. E. Review: The role of insulin resistance in nonalcoholic fatty liver disease. J. Clin. Endocrinol.Metab. 91, 4753-4761 (2006). (Pubitemid 44917301)
    • (2006) Journal of Clinical Endocrinology and Metabolism , vol.91 , Issue.12 , pp. 4753-4761
    • Utzschneider, K.M.1    Kahn, S.E.2
  • 30
    • 33749342069 scopus 로고    scopus 로고
    • Molecular mechanisms of insulin resistance: Serine phosphorylation of insulin receptor substrate-1 and increased expression of p85 α: The two sides of a coin
    • DOI 10.2337/db06-0391
    • Draznin, B. Molecular mechanisms of insulin resistance: serine phosphorylation of insulin receptor substrate-1 and increased expression of p85alpha: the two sides of a coin. Diabetes 55, 2392-2397 (2006). (Pubitemid 44743640)
    • (2006) Diabetes , vol.55 , Issue.8 , pp. 2392-2397
    • Draznin, B.1
  • 31
    • 34548098643 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3α in insulin action in cultured human skeletal muscle cells
    • DOI 10.1210/en.2006-0932
    • Ciaraldi, T. P., Nikoulina, S. E., Bandukwala, R. A., Carter, L. & Henry, R. R. Role of glycogen synthase kinase-3 alpha in insulin action in cultured human skeletal muscle cells. Endocrinology 148, 4393-4399 (2007). (Pubitemid 47295685)
    • (2007) Endocrinology , vol.148 , Issue.9 , pp. 4393-4399
    • Ciaraldi, T.P.1    Nikoulina, S.E.2    Bandukwala, R.A.3    Carter, L.4    Henry, R.R.5
  • 32
    • 79953107888 scopus 로고    scopus 로고
    • The effect of Lycium barbarum polysaccharide on alcoholinduced oxidative stress in rats
    • Cheng, D. & Kong, H. The effect of Lycium barbarum polysaccharide on alcoholinduced oxidative stress in rats. Molecules. 16, 2542-2550 (2011).
    • (2011) Molecules. , vol.16 , pp. 2542-2550
    • Cheng, D.1    Kong, H.2
  • 33
    • 55949096237 scopus 로고    scopus 로고
    • Effect of the Lycium barbarum polysaccharides administration on blood lipid metabolism and oxidative stress of mice fed high-fat diet in vivo
    • Ming, M., Guanhua, L., Zhanhai, Y., Guang, C. & Xuan, Z. Effect of the Lycium barbarum polysaccharides administration on blood lipid metabolism and oxidative stress of mice fed high-fat diet in vivo. Food Chem. 113, 872-877 (2009).
    • (2009) Food Chem. , vol.113 , pp. 872-877
    • Ming, M.1    Guanhua, L.2    Zhanhai, Y.3    Guang, C.4    Xuan, Z.5
  • 35
    • 34247198341 scopus 로고    scopus 로고
    • The forkhead transcription factor foxo1 regulates proliferation and transdifferentiation of hepatic stellate cells
    • DOI 10.1053/j.gastro.2007.01.033, PII S0016508507001680
    • Adachi, M. et al. The forkhead transcription factor FoxO1 regulates proliferation and transdifferentiation of hepatic stellate cells. Gastroenterology. 132, 1434-1446 (2007). (Pubitemid 46627569)
    • (2007) Gastroenterology , vol.132 , Issue.4 , pp. 1434-1446
    • Adachi, M.1    Osawa, Y.2    Uchinami, H.3    Kitamura, T.4    Accili, D.5    Brenner, D.A.6
  • 36
    • 0034803876 scopus 로고    scopus 로고
    • Transcription factor NF-kappaB as a potential biomarker for oxidative stress
    • van den Berg, R., Haenen, G. R., van den Berg, H. & Bast, A. Transcription factor NF-kappaB as a potential biomarker for oxidative stress. Br. J. Nutr. 86 Suppl 1, S121-127 (2001).
    • (2001) Br. J. Nutr. , vol.86 , Issue.SUPPL. 1
    • Van Den Berg, R.1    Haenen, G.R.2    Van Den Berg, H.3    Bast, A.4
  • 37
    • 79954428532 scopus 로고    scopus 로고
    • Effect of NF-kappaB signaling on apoptosis in chronic inflammation-associated carcinogenesis
    • Wang, H. & Cho, C. H. Effect of NF-kappaB signaling on apoptosis in chronic inflammation-associated carcinogenesis. Curr. Cancer Drug Targets. 10, 593-599 (2010).
    • (2010) Curr. Cancer Drug Targets. , vol.10 , pp. 593-599
    • Wang, H.1    Cho, C.H.2
  • 38
    • 84885945197 scopus 로고    scopus 로고
    • Involvement of free radicals and oxidative stress in NAFLD/NASH
    • Sumida, Y., Niki, E., Naito, Y. & Yoshikawa, T. Involvement of free radicals and oxidative stress in NAFLD/NASH. Free Radic. Res. 47, 869-880 (2013).
    • (2013) Free Radic. Res. , vol.47 , pp. 869-880
    • Sumida, Y.1    Niki, E.2    Naito, Y.3    Yoshikawa, T.4
  • 39
    • 84888800151 scopus 로고    scopus 로고
    • Resveratrol modulates autophagy and NF-kappaB activity in a murine model for treating non-alcoholic fatty liver disease
    • Li, L. et al. Resveratrol modulates autophagy and NF-kappaB activity in a murine model for treating non-alcoholic fatty liver disease. Food Chem. Toxicol. 63, 166-173 (2014).
    • (2014) Food Chem. Toxicol. , vol.63 , pp. 166-173
    • Li, L.1
  • 40
    • 66449114033 scopus 로고    scopus 로고
    • P62 at the crossroads of autophagy, apoptosis, and cancer
    • Moscat, J. & Diaz-Meco, M. T. p62 at the crossroads of autophagy, apoptosis, and cancer. Cell. 137, 1001-1004 (2009).
    • (2009) Cell. , vol.137 , pp. 1001-1004
    • Moscat, J.1    Diaz-Meco, M.T.2
  • 41
    • 33947697236 scopus 로고    scopus 로고
    • Inhibition of Lycium barbarum polysaccharides and Ganoderma lucidum polysaccharides against oxidative injury induced by γ-irradiation in rat liver mitochondria
    • DOI 10.1016/j.carbpol.2006.09.021, PII S014486170600467X
    • Li, X. L., Zhou, A. G. & Li, X. M. Inhibition of Lycium barbarum polysaccharides and Ganoderma lucidum polysaccharides against oxidative injury induced by c-irradiation in rat liver mitochondria. Carb. Pol. 69, 172-178 (2007). (Pubitemid 46497425)
    • (2007) Carbohydrate Polymers , vol.69 , Issue.1 , pp. 172-178
    • Li, X.L.1    Zhou, A.G.2    Li, X.M.3
  • 42
    • 67349180223 scopus 로고    scopus 로고
    • Chromatographic determination of polysaccharides in Lycium barbarumLinnaeus
    • Wang, C. C., Chang, S. C. & Chen, B. H. Chromatographic determination of polysaccharides in Lycium barbarumLinnaeus. Food Chem. 116, 595-603 (2009).
    • (2009) Food Chem. , vol.116 , pp. 595-603
    • Wang, C.C.1    Chang, S.C.2    Chen, B.H.3
  • 43
    • 44749092972 scopus 로고    scopus 로고
    • Determination of carotenoids and their esters in fruits of Lycium barbarum Linnaeus by HPLC-DAD-APCI-MS
    • Inbaraj, B. S. et al. Determination of carotenoids and their esters in fruits of Lycium barbarum Linnaeus by HPLC-DAD-APCI-MS. J. Pharm. Biomed. Anal. 47, 812-818 (2008).
    • (2008) J. Pharm. Biomed. Anal. , vol.47 , pp. 812-818
    • Inbaraj, B.S.1
  • 44
    • 30144443594 scopus 로고    scopus 로고
    • Quantification of zeaxanthin dipalmitate and total carotenoids in Lycium fruits (Fructus Lycii)
    • DOI 10.1007/s11130-005-9550-5
    • Peng, Y. et al. Quantification of zeaxanthin dipalmitate and total carotenoids in Lycium fruits (Fructus Lycii). Plant Foods Hum. Nutr. 60, 161-164 (2005). (Pubitemid 43052210)
    • (2005) Plant Foods for Human Nutrition , vol.60 , Issue.4 , pp. 161-164
    • Peng, Y.1    Ma, C.2    Li, Y.3    Leung, K.S.-Y.4    Jiang, Z.-H.5    Zhao, Z.6


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