Characterization of full-length recombinant human Proteoglycan 4 as an ocular surface boundary lubricant

Experimental Eye Research

Volumn 127, Issue , 2014, Pages 14-19

  Samsom, Michael L ^a   Morrison, Sheila ^a   Masala, Nemanja ^a   Sullivan, Benjamin D ^b   Sullivan, David A ^c,d   Sheardown, Heather ^e   Schmidt, Tannin A ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b TearLab Inc   (United States)

^c SCHEPENS EYE RESEARCH INSTITUTE   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e MCMASTER UNIVERSITY   (Canada)

Author keywords

Lubrication; Lubricin; Ocular surface; RhPRG4

Indexed keywords

ARTIFICIAL TEAR; DIMETICONE; GLYCOPROTEIN; OCULAR SURFACE BOUNDARY LUBRICANT; RECOMBINANT HUMAN PROTEOGLYCAN 4; UNCLASSIFIED DRUG; AGENTS ACTING ON THE EYE; LUBRICATING AGENT; PROTEOGLYCAN 4;

ANIMAL CELL; ARTICLE; CHO CELL LINE; CONTACT LENS; CORNEA; DRY EYE; EYELID; GLYCOSYLATION; HUMAN; IMMUNOREACTIVITY; LUBRICATION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; TANDEM MASS SPECTROMETRY; TOPICAL TREATMENT; WESTERN BLOTTING; AGED; CLINICAL ARTICLE; CULTURE MEDIUM; GENE EXPRESSION; HUMAN TISSUE; MOLECULAR WEIGHT; VELOCITY;

LUBRICATION; LUBRICIN; OCULAR SURFACE; RHPRG4;

AGED; ANIMALS; BLOTTING, WESTERN; CHO CELLS; CORNEA; CRICETULUS; DIMETHYLPOLYSILOXANES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EYELIDS; FRICTION; GLYCOSYLATION; HUMANS; LUBRICATION; MOLECULAR WEIGHT; OPHTHALMIC SOLUTIONS; PROTEOGLYCANS; RECOMBINANT PROTEINS; STRESS, PHYSIOLOGICAL; SURFACE PROPERTIES; TANDEM MASS SPECTROMETRY;

EID: 84904878301     PISSN: 00144835     EISSN: 10960007     Source Type: Journal    
DOI: 10.1016/j.exer.2014.06.015     Document Type: Article

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