Predicting both passive intestinal absorption and the dissociation constant toward albumin using the PAMPA technique

European Journal of Pharmaceutical Sciences

Volumn 63, Issue , 2014, Pages 36-44

  Bujard, Alban ^a   Sol, Marine ^a   Carrupt, Pierre Alain ^a   Martel, Sophie ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Constant of dissociation; Human serum albumin; PAMPA; Passive permeability; Permeation coefficient

Indexed keywords

DIMETHYL SULFOXIDE; HEXADECANE; HUMAN SERUM ALBUMIN; ALKANE; ARTIFICIAL MEMBRANE; N-HEXADECANE; SERUM ALBUMIN;

ARTICLE; ARTIFICIAL MEMBRANE; ASSAY; BINDING AFFINITY; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); DISSOCIATION CONSTANT; EQUILIBRIUM DIALYSIS; GOLD STANDARD; HIGH THROUGHPUT SCREENING; INTESTINE ABSORPTION; MEMBRANE PERMEABILITY; MEMBRANE TRANSPORT; PARALLEL ARTIFICIAL MEMBRANE PERMEABILITY ASSAY; PH; PREDICTION; PRIORITY JOURNAL; SIMULATION; CHEMISTRY; HUMAN; KINETICS; METABOLISM; PERMEABILITY;

ALKANES; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INTESTINAL ABSORPTION; KINETICS; MEMBRANES, ARTIFICIAL; PERMEABILITY; SERUM ALBUMIN;

EID: 84904865686     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2014.06.025     Document Type: Article

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