-
1
-
-
67349086295
-
Analytical tools for the physicochemical profiling of drug candidates to predict absorption/distribution
-
Y. Henchoz Analytical tools for the physicochemical profiling of drug candidates to predict absorption/distribution Anal. Bioanal. Chem. 394 2009 707 729
-
(2009)
Anal. Bioanal. Chem.
, vol.394
, pp. 707-729
-
-
Henchoz, Y.1
-
2
-
-
0042330313
-
ADME-Tox in drug discovery: Integration of experimental and computational technologies
-
H.S. Yu, and A. Adedoyin ADME-Tox in drug discovery: integration of experimental and computational technologies Drug Discov. Today 8 2003 852 861
-
(2003)
Drug Discov. Today
, vol.8
, pp. 852-861
-
-
Yu, H.S.1
Adedoyin, A.2
-
3
-
-
84866739808
-
Drug discovery in pharmaceutical industry: Productivity challenges and trends
-
I. Khanna Drug discovery in pharmaceutical industry: productivity challenges and trends Drug Discov. Today 17 2012 1088 1102
-
(2012)
Drug Discov. Today
, vol.17
, pp. 1088-1102
-
-
Khanna, I.1
-
4
-
-
34447503927
-
The importance of plasma protein binding in drug discovery
-
G.L. Trainor The importance of plasma protein binding in drug discovery Expert Opin. Drug Discov. 2 2007 51 64
-
(2007)
Expert Opin. Drug Discov.
, vol.2
, pp. 51-64
-
-
Trainor, G.L.1
-
5
-
-
79960495668
-
Plasma protein binding and blood-free concentrations: Which studies are needed to develop a drug?
-
M. Pellegatti Plasma protein binding and blood-free concentrations: which studies are needed to develop a drug? Expert Opin. Drug Metab. Toxicol. 7 2011 1009 1020
-
(2011)
Expert Opin. Drug Metab. Toxicol.
, vol.7
, pp. 1009-1020
-
-
Pellegatti, M.1
-
6
-
-
0036828938
-
Predicting plasma protein binding of drugs: A new approach
-
N.A. Kratochwil Predicting plasma protein binding of drugs: a new approach Biochem. Pharmacol. 64 2002 1355 1374
-
(2002)
Biochem. Pharmacol.
, vol.64
, pp. 1355-1374
-
-
Kratochwil, N.A.1
-
8
-
-
84885829171
-
Protein binding of drugs
-
M. Hu, X. Li, John Wiley & Sons
-
A. Kotsiou, and C. Tesseromatis Protein binding of drugs M. Hu, X. Li, Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications 2011 John Wiley & Sons 145 166
-
(2011)
Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications
, pp. 145-166
-
-
Kotsiou, A.1
Tesseromatis, C.2
-
9
-
-
77955933364
-
Drug-protein binding: A critical review of analytical tools
-
K. Vuignier Drug-protein binding: a critical review of analytical tools Anal. Bioanal. Chem. 398 2010 53 66
-
(2010)
Anal. Bioanal. Chem.
, vol.398
, pp. 53-66
-
-
Vuignier, K.1
-
10
-
-
84866364055
-
Investigating metabolite-protein interactions: An overview of available techniques
-
G.X. Yang Investigating metabolite-protein interactions: an overview of available techniques Methods 57 2012 459 466
-
(2012)
Methods
, vol.57
, pp. 459-466
-
-
Yang, G.X.1
-
11
-
-
60749101939
-
Plasma/serum protein binding determinations
-
M.J. Banker, and T.H. Clark Plasma/serum protein binding determinations Curr. Drug Metab. 9 2008 854 859
-
(2008)
Curr. Drug Metab.
, vol.9
, pp. 854-859
-
-
Banker, M.J.1
Clark, T.H.2
-
13
-
-
0344365022
-
Methods in drug protein binding analysis
-
H. Kuemmerle, Elsevier Science Publishers
-
R. Zini Methods in drug protein binding analysis H. Kuemmerle, Human Pharmacology. The Basis of Clinical Pharmacology 1991 Elsevier Science Publishers 235 282
-
(1991)
Human Pharmacology. The Basis of Clinical Pharmacology
, pp. 235-282
-
-
Zini, R.1
-
14
-
-
80051871865
-
Predicting human plasma protein binding of drugs using plasma protein interaction QSAR analysis (PPI-QSAR)
-
H. Li Predicting human plasma protein binding of drugs using plasma protein interaction QSAR analysis (PPI-QSAR) Biopharm. Drug Dispos. 32 2011 333 342
-
(2011)
Biopharm. Drug Dispos.
, vol.32
, pp. 333-342
-
-
Li, H.1
-
15
-
-
0037404491
-
In silico prediction of drug-binding strengths to human serum albumin
-
G. Colmenarejo In silico prediction of drug-binding strengths to human serum albumin Med. Res. Rev. 23 2003 275 301
-
(2003)
Med. Res. Rev.
, vol.23
, pp. 275-301
-
-
Colmenarejo, G.1
-
16
-
-
25144505772
-
Structural basis of the drug-binding specificity of human serum albumin
-
J. Ghuman Structural basis of the drug-binding specificity of human serum albumin J. Mol. Biol. 353 2005 38 52
-
(2005)
J. Mol. Biol.
, vol.353
, pp. 38-52
-
-
Ghuman, J.1
-
17
-
-
0034684197
-
Alpha-1-acid glycoprotein
-
T. Fournier Alpha-1-acid glycoprotein Biochim. Biophys. Acta 1482 2000 157 171
-
(2000)
Biochim. Biophys. Acta
, vol.1482
, pp. 157-171
-
-
Fournier, T.1
-
18
-
-
84871773262
-
High performance affinity chromatography (HPAC) as a high-throughput screening tool in drug discovery to study drug plasma protein interactions
-
K. Vuignier High performance affinity chromatography (HPAC) as a high-throughput screening tool in drug discovery to study drug plasma protein interactions J. Pharm. Biomed. Anal. 74 2013 205 212
-
(2013)
J. Pharm. Biomed. Anal.
, vol.74
, pp. 205-212
-
-
Vuignier, K.1
-
19
-
-
84865075245
-
Pharmaceutical and biomedical applications of affinity chromatography: Recent trends and developments
-
D.S. Hage Pharmaceutical and biomedical applications of affinity chromatography: recent trends and developments J. Pharm. Biomed. Anal. 69 2012 93 105
-
(2012)
J. Pharm. Biomed. Anal.
, vol.69
, pp. 93-105
-
-
Hage, D.S.1
-
20
-
-
0242290408
-
Fast gradient HPLC method to determine compounds binding to human serum albumin. Relationships with octanol/water and immobilized artificial membrane lipophilicity
-
R.K. Valko Fast gradient HPLC method to determine compounds binding to human serum albumin. Relationships with octanol/water and immobilized artificial membrane lipophilicity J. Pharm. Sci. 92 2003 2236 2248
-
(2003)
J. Pharm. Sci.
, vol.92
, pp. 2236-2248
-
-
Valko, R.K.1
-
21
-
-
84869784897
-
Characterization of drug-protein interactions by capillary electrophoresis hyphenated to mass spectrometry
-
K. Vuignier Characterization of drug-protein interactions by capillary electrophoresis hyphenated to mass spectrometry Electrophoresis 33 2012 3306 3315
-
(2012)
Electrophoresis
, vol.33
, pp. 3306-3315
-
-
Vuignier, K.1
-
22
-
-
0035884143
-
High-resolution and high-throughput protocols for measuring drug/human serum albumin interactions using BIACORE
-
R.L. Rich High-resolution and high-throughput protocols for measuring drug/human serum albumin interactions using BIACORE Anal. Biochem. 296 2001 197 207
-
(2001)
Anal. Biochem.
, vol.296
, pp. 197-207
-
-
Rich, R.L.1
-
23
-
-
0346504117
-
Capillary electrophoresis frontal analysis: Principles and applications for the study of drug-plasma protein binding
-
J. Ostergaard, and N.H.H. Heegaard Capillary electrophoresis frontal analysis: principles and applications for the study of drug-plasma protein binding Electrophoresis 24 2003 2903 2913
-
(2003)
Electrophoresis
, vol.24
, pp. 2903-2913
-
-
Ostergaard, J.1
Heegaard, N.H.H.2
-
24
-
-
13344250393
-
Why you should be using more SPR biosensor technology
-
R.L. Rich, and D.G. Myszka Why you should be using more SPR biosensor technology Drug Discov. Today: Technol. 1 2004 301 308
-
(2004)
Drug Discov. Today: Technol.
, vol.1
, pp. 301-308
-
-
Rich, R.L.1
Myszka, D.G.2
-
25
-
-
33750565735
-
Biomolecular interaction analysis in drug discovery using surface plasmon resonance technology
-
W. Huber, and F. Mueller Biomolecular interaction analysis in drug discovery using surface plasmon resonance technology Curr. Pharm. Des. 12 2006 3999 4021
-
(2006)
Curr. Pharm. Des.
, vol.12
, pp. 3999-4021
-
-
Huber, W.1
Mueller, F.2
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