Identification and mutagenesis of the TACE and γ-secretase cleavage sites in the colony-stimulating factor 1 receptor

Biochemical and Biophysical Research Communications

Volumn 450, Issue 1, 2014, Pages 782-787

  Vahidi, Arrash ^a   Glenn, Gary ^a   Van Der Geer, Peter ^a  

^a SAN DIEGO STATE UNIVERSITY   (United States)

Author keywords

Cleavage site selection; Ectodomain shedding; Intramembrane proteolysis; Protein tyrosine kinase; Signal transduction

Indexed keywords

COLONY STIMULATING FACTOR 1 RECEPTOR; COLONY STIMULATING FACTOR RECEPTOR; GAMMA SECRETASE; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME SUBSTRATE COMPLEX; HUMAN; HUMAN CELL; MACROPHAGE ACTIVATION; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION;

BACTERIA (MICROORGANISMS);

CLEAVAGE SITE SELECTION; ECTODOMAIN SHEDDING; INTRAMEMBRANE PROTEOLYSIS; PROTEIN-TYROSINE KINASE; SIGNAL TRANSDUCTION;

ADAM PROTEINS; AMYLOID PRECURSOR PROTEIN SECRETASES; BINDING SITES; ENZYME ACTIVATION; HEK293 CELLS; HUMANS; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR;

EID: 84904765851     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.06.061     Document Type: Article

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