메뉴 건너뛰기




Volumn 5 JUN, Issue , 2014, Pages 1-14

Discovering novel neuroactive drugs through high-throughput behavior-based chemical screening in the zebrafish

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; ANXIOLYTIC AGENT; NEUROLEPTIC AGENT; NEW DRUG; PSYCHOTROPIC AGENT;

EID: 84904765812     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2014.00153     Document Type: Article
Times cited : (68)

References (96)
  • 2
    • 79952116174 scopus 로고    scopus 로고
    • Prescription drug use continues to increase: U.S. prescription drug data for 2007-2008
    • Gu, Q., Dillon, C. F. & Burt, V. L. Prescription drug use continues to increase: U.S. prescription drug data for 2007-2008. NCHS Data Brief1-8 (2010).
    • (2010) NCHS Data Brief1-8
    • Gu, Q.1    Dillon, C.F.2    Burt, V.L.3
  • 3
    • 2542436007 scopus 로고    scopus 로고
    • Psychotropic drug utilization in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project
    • Alonso, J. et al. Psychotropic drug utilization in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatr Scand Suppl 109, 55-64 (2004).
    • (2004) Acta Psychiatr Scand Suppl , vol.109 , pp. 55-64
    • Alonso, J.1
  • 4
    • 84896841974 scopus 로고    scopus 로고
    • National trends in long-term use of antidepressant medications: results from the U.S. National Health and Nutrition Examination Survey
    • Mojtabai, R. & Olfson, M. National trends in long-term use of antidepressant medications: results from the U.S. National Health and Nutrition Examination Survey. J Clin Psychiatry 75,169-177 (2014).
    • (2014) J Clin Psychiatry , vol.75 , pp. 169-177
    • Mojtabai, R.1    Olfson, M.2
  • 5
    • 84898751804 scopus 로고    scopus 로고
    • Trends in office-based mental health care provided by psychiatrists and primary care physicians
    • Olfson, M., Kroenke, K., Wang, S. & Blanco, C. Trends in office-based mental health care provided by psychiatrists and primary care physicians. J Clin Psychiatry 75, 247-253 (2014).
    • (2014) J Clin Psychiatry , vol.75 , pp. 247-253
    • Olfson, M.1    Kroenke, K.2    Wang, S.3    Blanco, C.4
  • 6
    • 77649234756 scopus 로고    scopus 로고
    • How to improve R&D productivity: the pharmaceutical industry's grand challenge
    • Paul, S. M. et al. How to improve R&D productivity: the pharmaceutical industry's grand challenge. NatRevDrugDiscov9, 203-214 (2010).
    • (2010) NatRevDrugDiscov9 , pp. 203-214
    • Paul, S.M.1
  • 7
    • 0014424692 scopus 로고
    • Comprehensive observational assessment: Ia. A systematic, quantitative procedure for assessing the behavioral and physiologic state of the mouse
    • Irwin, S. Comprehensive observational assessment: Ia. A systematic, quantitative procedure for assessing the behavioral and physiologic state of the mouse. Psychopharmacology (Berl.) 13, 222-257(1968).
    • (1968) Psychopharmacology (Berl.) , vol.13 , pp. 222-257
    • Irwin, S.1
  • 8
    • 2142827072 scopus 로고    scopus 로고
    • Neurobehavioral assessment in the information age
    • Tecott, L. H. & Nestler, E. J. Neurobehavioral assessment in the information age. Nature Neuroscience 7, 462-466 (2004).
    • (2004) Nature Neuroscience , vol.7 , pp. 462-466
    • Tecott, L.H.1    Nestler, E.J.2
  • 10
    • 58149380087 scopus 로고    scopus 로고
    • Chemobehavioural phenomics and behaviour-based psychiatric drug discovery in the zebrafish
    • Kokel, D. & Peterson, R. T. Chemobehavioural phenomics and behaviour-based psychiatric drug discovery in the zebrafish. Brief Funct Genomic Proteomic 7, 483-490 (2008).
    • (2008) Brief Funct Genomic Proteomic , vol.7 , pp. 483-490
    • Kokel, D.1    Peterson, R.T.2
  • 11
    • 65649116136 scopus 로고    scopus 로고
    • Challenges in the search for drugs to treat central nervous system disorders
    • Enna, S. J. & Williams, M. Challenges in the search for drugs to treat central nervous system disorders. J. Pharmacol. Exp. Ther. 329, 404-411 (2009).
    • (2009) J. Pharmacol. Exp. Ther. , vol.329 , pp. 404-411
    • Enna, S.J.1    Williams, M.2
  • 13
    • 80053215800 scopus 로고    scopus 로고
    • Efficacy and comparative effectiveness of atypical antipsychotic medications for off-label uses in adults: a systematic review and meta-analysis
    • Maher, A. R. et al. Efficacy and comparative effectiveness of atypical antipsychotic medications for off-label uses in adults: a systematic review and meta-analysis. JAMA 306,1359-1369 (2011).
    • (2011) JAMA , vol.306 , pp. 1359-1369
    • Maher, A.R.1
  • 15
    • 33745432015 scopus 로고    scopus 로고
    • The search for new off-label indications for antidepressant, antianxiety, antipsychotic and anticonvulsant drugs
    • Chouinard, G. The search for new off-label indications for antidepressant, antianxiety, antipsychotic and anticonvulsant drugs. J Psychiatry Neurosci 31,168-176 (2006).
    • (2006) J Psychiatry Neurosci , vol.31 , pp. 168-176
    • Chouinard, G.1
  • 16
    • 84904728097 scopus 로고    scopus 로고
    • FDALabel. at
    • FDALabel. at
  • 17
    • 79959975084 scopus 로고    scopus 로고
    • ChemMine tools: an online service for analyzing and clustering small molecules
    • Backman, T. W. H., Cao, Y. & Girke, T. ChemMine tools: an online service for analyzing and clustering small molecules. Nucleic Acids Res. 39, W486-91 (2011).
    • (2011) Nucleic Acids Res , vol.39
    • Backman, T.W.H.1    Cao, Y.2    Girke, T.3
  • 20
    • 33845728490 scopus 로고    scopus 로고
    • Hypocretin/Orexin Overexpression Induces An Insomnia-Like Phenotype in Zebrafish
    • Prober, D. A., Rihel, J., Onah, A. A., Sung, R. J. & Schier, A. F. Hypocretin/Orexin Overexpression Induces An Insomnia-Like Phenotype in Zebrafish. J. Neurosci. 26,13400-13410 (2006).
    • (2006) J. Neurosci. , vol.26 , pp. 13400-13410
    • Prober, D.A.1    Rihel, J.2    Onah, A.A.3    Sung, R.J.4    Schier, A.F.5
  • 21
    • 74549126594 scopus 로고    scopus 로고
    • Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation
    • Rihel, J. et al. Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation. Science 327, 348-351 (2010).
    • (2010) Science , vol.327 , pp. 348-351
    • Rihel, J.1
  • 22
    • 35648976615 scopus 로고    scopus 로고
    • Characterization of sleep in zebrafish and insomnia in hypocretin receptor mutants
    • Yokogawa, T. et al. Characterization of sleep in zebrafish and insomnia in hypocretin receptor mutants. PLoSBiol. 5, e277 (2007).
    • (2007) PLoSBiol , vol.5
    • Yokogawa, T.1
  • 23
    • 33745579027 scopus 로고    scopus 로고
    • Sleep in zebrafish
    • Zhdanova, I. V. Sleep in zebrafish. Zebrafish 3, 215-226 (2006).
    • (2006) Zebrafish , vol.3 , pp. 215-226
    • Zhdanova, I.V.1
  • 24
    • 54049132922 scopus 로고    scopus 로고
    • Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function
    • Prober, D. A. et al. Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function. J. Neurosci. 28,10102-10110 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 10102-10110
    • Prober, D.A.1
  • 25
    • 78049318443 scopus 로고    scopus 로고
    • The habenula is crucial for experience-dependent modification of fear responses in zebrafish
    • Agetsuma, M. et al. The habenula is crucial for experience-dependent modification of fear responses in zebrafish. Nature Neuroscience 13,1354-1356 (2010).
    • (2010) Nature Neuroscience , vol.13 , pp. 1354-1356
    • Agetsuma, M.1
  • 26
    • 84858665565 scopus 로고    scopus 로고
    • Chondroitin fragments are odorants that trigger fear behavior in fish
    • Mathuru, A. S. et al. Chondroitin fragments are odorants that trigger fear behavior in fish. Curr. Biol. 22,538-544(2012).
    • (2012) Curr. Biol. , vol.22 , pp. 538-544
    • Mathuru, A.S.1
  • 27
    • 38749106264 scopus 로고    scopus 로고
    • Alarm substance induced behavioral responses in zebrafish (Danio rerio). Behav
    • Speedie, N. & Gerlai, R. Alarm substance induced behavioral responses in zebrafish (Danio rerio). Behav. Brain Res. 188,168-177 (2008).
    • (2008) Brain Res , vol.188 , pp. 168-177
    • Speedie, N.1    Gerlai, R.2
  • 28
    • 78650510273 scopus 로고    scopus 로고
    • The habenula prevents helpless behavior in larval zebrafish
    • Lee, A. et al. The habenula prevents helpless behavior in larval zebrafish. Curr. Biol. 20, 2211-2216 (2010).
    • (2010) Curr. Biol. , vol.20 , pp. 2211-2216
    • Lee, A.1
  • 29
    • 27144512133 scopus 로고    scopus 로고
    • Visual prey capture in larval zebrafish is controlled by identified reticulospinal neurons downstream of the tectum
    • Gahtan, E., Tanger, P. & Baier, H. Visual prey capture in larval zebrafish is controlled by identified reticulospinal neurons downstream of the tectum. J. Neurosci. 25, 9294-9303 (2005).
    • (2005) J. Neurosci. , vol.25 , pp. 9294-9303
    • Gahtan, E.1    Tanger, P.2    Baier, H.3
  • 30
    • 84856185910 scopus 로고    scopus 로고
    • Prey capture behavior evoked by simple visual stimuli in larval zebrafish
    • Bianco, I. H., Kampff, A. R. & Engert, F. Prey capture behavior evoked by simple visual stimuli in larval zebrafish. FrontSyst Neurosci 5,101 (2011).
    • (2011) FrontSyst Neurosci , vol.5 , pp. 101
    • Bianco, I.H.1    Kampff, A.R.2    Engert, F.3
  • 31
    • 77957367474 scopus 로고    scopus 로고
    • Filtering of visual information in the tectum by an identified neural circuit
    • Del Bene, F. et al. Filtering of visual information in the tectum by an identified neural circuit. Science 330, 669-673 (2010).
    • (2010) Science , vol.330 , pp. 669-673
    • Del Bene, F.1
  • 32
    • 33746020597 scopus 로고    scopus 로고
    • Characterization and development of courtship in zebrafish
    • Darrow, K. O. & Harris, W. A. Characterization and development of courtship in zebrafish, Danio rerio. Zebrafish 1, 40-45 (2004).
    • (2004) Danio rerio. Zebrafish , vol.1 , pp. 40-45
    • Darrow, K.O.1    Harris, W.A.2
  • 33
    • 84859851428 scopus 로고    scopus 로고
    • Ontogeny of classical and operant learning behaviors in zebrafish
    • Valente, A., Huang, K. H., Portugues, R. & Engert, F. Ontogeny of classical and operant learning behaviors in zebrafish. Learn. Mem. 19,170-177 (2012).
    • (2012) Learn. Mem. , vol.19 , pp. 170-177
    • Valente, A.1    Huang, K.H.2    Portugues, R.3    Engert, F.4
  • 34
    • 37649017562 scopus 로고    scopus 로고
    • OFF ganglion cells cannot drive the optokinetic reflex in zebrafish
    • Emran, F. et al. OFF ganglion cells cannot drive the optokinetic reflex in zebrafish. Proc. Natl. Acad. Sci. U.S.A. 104, 19126-19131 (2007).
    • (2007) Proc. Natl. Acad. Sci. U. S. A. , vol.104 , pp. 19126-19131
    • Emran, F.1
  • 35
    • 75849125874 scopus 로고    scopus 로고
    • The transmembrane inner ear (Tmie) protein is essential for normal hearing and balance in the zebrafish
    • Gleason, M. R. et al. The transmembrane inner ear (Tmie) protein is essential for normal hearing and balance in the zebrafish. Proc. Natl. Acad. Sci. U.S.A. 106, 21347-21352 (2009).
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 21347-21352
    • Gleason, M.R.1
  • 36
    • 84863308047 scopus 로고    scopus 로고
    • Touch responsiveness in zebrafish requires voltage-gated calcium channel 2.1b
    • Low, S. E. et al. Touch responsiveness in zebrafish requires voltage-gated calcium channel 2.1b. J. Neurophysiol. 108,148-159 (2012).
    • (2012) J. Neurophysiol. , vol.108 , pp. 148-159
    • Low, S.E.1
  • 37
    • 77954749589 scopus 로고    scopus 로고
    • touché Is required for touch-evoked generator potentials within vertebrate sensory neurons
    • Low, S. E. et al. touché Is required for touch-evoked generator potentials within vertebrate sensory neurons. J. Neurosci. 30, 9359-9367 (2010).
    • (2010) J. Neurosci , vol.30 , pp. 9359-9367
    • Low, S.E.1
  • 38
    • 80051570561 scopus 로고    scopus 로고
    • TRPM7 is required within zebrafish sensory neurons for the activation of touchevoked escape behaviors
    • Low, S. E. et al. TRPM7 is required within zebrafish sensory neurons for the activation of touchevoked escape behaviors. J. Neurosci. 31,11633-11644 (2011).
    • (2011) J. Neurosci. , vol.31 , pp. 11633-11644
    • Low, S.E.1
  • 39
    • 84875834157 scopus 로고    scopus 로고
    • Maturation of shoaling in two zebrafish strains: a behavioral and neurochemical analysis. Behav
    • Mahabir, S., Chatterjee, D., Buske, C. & Gerlai, R. Maturation of shoaling in two zebrafish strains: a behavioral and neurochemical analysis. Behav. Brain Res. 247,1-8 (2013).
    • (2013) Brain Res , vol.247 , pp. 1-8
    • Mahabir, S.1    Chatterjee, D.2    Buske, C.3    Gerlai, R.4
  • 40
    • 84901381666 scopus 로고    scopus 로고
    • Induction of Social Behavior in Zebrafish: Live Versus Computer Animated Fish as Stimuli
    • doi:10.1089/zeb.2013.0969, 140227075646004
    • Qin, M., Wong, A., Seguin, D. & Gerlai, R. Induction of Social Behavior in Zebrafish: Live Versus Computer Animated Fish as Stimuli. Zebrafish 140227075646004 (2014). doi:10.1089/zeb.2013.0969
    • (2014) Zebrafish
    • Qin, M.1    Wong, A.2    Seguin, D.3    Gerlai, R.4
  • 41
    • 84859245496 scopus 로고    scopus 로고
    • Collective animal behavior from Bayesian estimation and probability matching
    • Pérez-Escudero, A. & de Polavieja, G. G. Collective animal behavior from Bayesian estimation and probability matching. PLoS Comput. Biol. 7, e1002282 (2011).
    • (2011) PLoS Comput. Biol. , vol.7
    • Pérez-Escudero, A.1    de Polavieja, G.G.2
  • 42
    • 80054094464 scopus 로고    scopus 로고
    • Modeling anxiety using adult zebrafish: a conceptual review
    • Stewart, A. et al. Modeling anxiety using adult zebrafish: a conceptual review. Neuropharmacology 62,135-143(2012).
    • (2012) Neuropharmacology , vol.62 , pp. 135-143
    • Stewart, A.1
  • 44
    • 84891745958 scopus 로고    scopus 로고
    • The behavioral effects of acute Δ -tetrahydrocannabinol and heroin (diacetylmorphine) exposure in adult zebrafish
    • Stewart, A. M. & Kalueff, A. V. The behavioral effects of acute Δ -tetrahydrocannabinol and heroin (diacetylmorphine) exposure in adult zebrafish. Brain Res. 1543,109-119 (2014).
    • (2014) Brain Res , vol.1543 , pp. 109-119
    • Stewart, A.M.1    Kalueff, A.V.2
  • 45
    • 81855175313 scopus 로고    scopus 로고
    • Behavioral and physiological effects of RDX on adult zebrafish
    • Williams, L. R. et al. Behavioral and physiological effects of RDX on adult zebrafish. Comp. Biochem. Physiol. C Toxicol. Pharmacol. 155, 33-38 (2012).
    • (2012) Comp. Biochem. Physiol. C Toxicol. Pharmacol. , vol.155 , pp. 33-38
    • Williams, L.R.1
  • 46
    • 84881177825 scopus 로고    scopus 로고
    • Behavioral effects of bidirectional modulators of brain monoamines reserpine and damphetamine in zebrafish
    • Kyzar, E. etal. Behavioral effects of bidirectional modulators of brain monoamines reserpine and damphetamine in zebrafish. Brain Res. 1527,108-116 (2013).
    • (2013) Brain Res , vol.1527 , pp. 108-116
    • Kyzar, E.1
  • 47
    • 79955472632 scopus 로고    scopus 로고
    • Behavioral effects of MDMA (ecstasy) on adult zebrafish
    • Stewart, A. et al. Behavioral effects of MDMA (ecstasy) on adult zebrafish. Behav Pharmacol 22, 275-280(2011).
    • (2011) Behav Pharmacol , vol.22 , pp. 275-280
    • Stewart, A.1
  • 48
    • 84857791354 scopus 로고    scopus 로고
    • Effects of hallucinogenic agents mescaline and phencyclidine on zebrafish behavior and physiology
    • Kyzar, E. J. et al. Effects of hallucinogenic agents mescaline and phencyclidine on zebrafish behavior and physiology. Progress in Neuro-Psychopharmacology and Biological Psychiatry 37,194-202 (2012).
    • (2012) Progress in Neuro-Psychopharmacology and Biological Psychiatry , vol.37 , pp. 194-202
    • Kyzar, E.J.1
  • 49
    • 79954629310 scopus 로고    scopus 로고
    • Effects of piracetam on behavior and memory in adult zebrafish
    • Grossman, L. et al. Effects of piracetam on behavior and memory in adult zebrafish. Brain Res. Bull. 85,58-63(2011).
    • (2011) Brain Res. Bull , vol.85 , pp. 58-63
    • Grossman, L.1
  • 50
    • 84877638473 scopus 로고    scopus 로고
    • Psychopharmacological effects of acute exposure to kynurenic acid (KYNA) in zebrafish
    • Robinson, K. S. L. et al. Psychopharmacological effects of acute exposure to kynurenic acid (KYNA) in zebrafish. Pharmacology Biochemistry and Behavior 108, 54-60 (2013).
    • (2013) Pharmacology Biochemistry and Behavior , vol.108 , pp. 54-60
    • Robinson, K.S.L.1
  • 52
    • 70349295632 scopus 로고    scopus 로고
    • Optogenetic dissection of a behavioural module in the vertebrate spinal cord
    • Wyart, C. et al. Optogenetic dissection of a behavioural module in the vertebrate spinal cord. Nature 461, 407-410 (2009).
    • (2009) Nature , vol.461 , pp. 407-410
    • Wyart, C.1
  • 53
    • 84874616928 scopus 로고    scopus 로고
    • Identification of Nonvisual Photomotor Response Cells in the Vertebrate Hindbrain
    • Kokel, D. et al. Identification of Nonvisual Photomotor Response Cells in the Vertebrate Hindbrain. J. Neurosci. 33, 3834-3843 (2013).
    • (2013) J. Neurosci. , vol.33 , pp. 3834-3843
    • Kokel, D.1
  • 54
    • 77249135113 scopus 로고    scopus 로고
    • Rapid behavior-based identification of neuroactive small molecules in the zebrafish
    • Kokel, D. et al. Rapid behavior-based identification of neuroactive small molecules in the zebrafish. Nature Publishing Group 6, 231-237 (2010).
    • (2010) Nature Publishing Group , vol.6 , pp. 231-237
    • Kokel, D.1
  • 55
    • 77958082168 scopus 로고    scopus 로고
    • Drug discovery in a multidimensional world: systems, patterns, and networks
    • Dudley, J. T., Schadt, E., Sirota, M., Butte, A. J. & Ashley, E. Drug discovery in a multidimensional world: systems, patterns, and networks. J Cardiovasc TranslRes 3, 438-447 (2010).
    • (2010) J Cardiovasc TranslRes , vol.3 , pp. 438-447
    • Dudley, J.T.1    Schadt, E.2    Sirota, M.3    Butte, A.J.4    Ashley, E.5
  • 57
    • 34547766473 scopus 로고    scopus 로고
    • Modulation of locomotor activity in larval zebrafish during light adaptation
    • Burgess, H. A. & Granato, M. Modulation of locomotor activity in larval zebrafish during light adaptation. Journal of Experimental Biology 210, 2526-2539 (2007).
    • (2007) Journal of Experimental Biology , vol.210 , pp. 2526-2539
    • Burgess, H.A.1    Granato, M.2
  • 58
    • 84874611717 scopus 로고    scopus 로고
    • High-throughput hyperdimensional vertebrate phenotyping
    • Pardo-Martin, C. et al. High-throughput hyperdimensional vertebrate phenotyping. Nat Comms 4, 1467 (2013).
    • (2013) Nat Comms , vol.4 , pp. 1467
    • Pardo-Martin, C.1
  • 59
    • 77955169046 scopus 로고    scopus 로고
    • High-throughput in vivo vertebrate screening
    • Pardo-Martin, C. et al. High-throughput in vivo vertebrate screening. Nature Publishing Group 7, 634-636(2010).
    • (2010) Nature Publishing Group , vol.7 , pp. 634-636
    • Pardo-Martin, C.1
  • 60
    • 84872063885 scopus 로고    scopus 로고
    • Fish in the matrix: motor learning in a virtual world
    • Engert, F. Fish in the matrix: motor learning in a virtual world. Front Neural Circuits 6,125 (2012).
    • (2012) Front Neural Circuits , vol.6 , pp. 125
    • Engert, F.1
  • 62
    • 84867609315 scopus 로고    scopus 로고
    • Facilitating drug discovery: an automated high-content inflammation assay in zebrafish
    • doi:10.3791/4203
    • Wittmann, C. et al. Facilitating drug discovery: an automated high-content inflammation assay in zebrafish. J Vis Exp e4203-e4203 (2012). doi:10.3791/4203
    • (2012) J Vis Exp
    • Wittmann, C.1
  • 63
    • 76749091914 scopus 로고    scopus 로고
    • Distinct retinal pathways drive spatial orientation behaviors in zebrafish navigation
    • Burgess, H. A., Schoch, H. & Granato, M. Distinct retinal pathways drive spatial orientation behaviors in zebrafish navigation. Curr. Biol. 20, 381-386 (2010).
    • (2010) Curr. Biol. , vol.20 , pp. 381-386
    • Burgess, H.A.1    Schoch, H.2    Granato, M.3
  • 64
    • 34247857650 scopus 로고    scopus 로고
    • Sensorimotor gating in larval zebrafish
    • Burgess, H. A. & Granato, M. Sensorimotor gating in larval zebrafish. J. Neurosci. 27, 4984-4994 (2007).
    • (2007) J. Neurosci. , vol.27 , pp. 4984-4994
    • Burgess, H.A.1    Granato, M.2
  • 65
    • 67650486967 scopus 로고    scopus 로고
    • Unidirectional startle responses and disrupted left-right co-ordination of motor behaviors in robo3 mutant zebrafish
    • Burgess, H. A., Johnson, S. L. & Granato, M. Unidirectional startle responses and disrupted left-right co-ordination of motor behaviors in robo3 mutant zebrafish. Genes Brain Behav. 8, 500-511 (2009).
    • (2009) Genes Brain Behav , vol.8 , pp. 500-511
    • Burgess, H.A.1    Johnson, S.L.2    Granato, M.3
  • 67
    • 84868533402 scopus 로고    scopus 로고
    • Repor tDeep Brain Photoreceptors Control Light-Seeking Behavior in Zebrafish Larvae
    • Fernandes, A. M. et al. Repor tDeep Brain Photoreceptors Control Light-Seeking Behavior in Zebrafish Larvae. Current Biology 22, 2042-2047 (2012).
    • (2012) Current Biology , vol.22 , pp. 2042-2047
    • Fernandes, A.M.1
  • 69
    • 84877585171 scopus 로고    scopus 로고
    • Whole-brain functional imaging at cellular resolution using light-sheet microscopy
    • Ahrens, M. B., Orger, M. B., Robson, D. N., Li, J. M. & Keller, P. J. Whole-brain functional imaging at cellular resolution using light-sheet microscopy. Nature Publishing Group 10, 413-420 (2013).
    • (2013) Nature Publishing Group , vol.10 , pp. 413-420
    • Ahrens, M.B.1    Orger, M.B.2    Robson, D.N.3    Li, J.M.4    Keller, P.J.5
  • 70
    • 84874662333 scopus 로고    scopus 로고
    • Real-time visualization of neuronal activity during perception
    • Muto, A., Ohkura, M., Abe, G., Nakai, J. & Kawakami, K. Real-time visualization of neuronal activity during perception. Curr. Biol. 23, 307-311 (2013).
    • (2013) Curr. Biol. , vol.23 , pp. 307-311
    • Muto, A.1    Ohkura, M.2    Abe, G.3    Nakai, J.4    Kawakami, K.5
  • 71
    • 84883216511 scopus 로고    scopus 로고
    • Transgenic tools to characterize neuronal properties of discrete populations of zebrafish neurons
    • Satou, C. et al. Transgenic tools to characterize neuronal properties of discrete populations of zebrafish neurons. Development 140, 3927-3931 (2013).
    • (2013) Development , vol.140 , pp. 3927-3931
    • Satou, C.1
  • 72
    • 84896282038 scopus 로고    scopus 로고
    • Whole-Brain Activity Maps Reveal Stereotyped, Distributed Networks for Visuomotor Behavior
    • Portugues, R., Feierstein, C. E., Engert, F. & Orger, M. B. Whole-Brain Activity Maps Reveal Stereotyped, Distributed Networks for Visuomotor Behavior. Neuron 81,1328-1343 (2014).
    • (2014) Neuron , vol.81 , pp. 1328-1343
    • Portugues, R.1    Feierstein, C.E.2    Engert, F.3    Orger, M.B.4
  • 73
    • 84856194886 scopus 로고    scopus 로고
    • Fully automated cellularresolution vertebrate screening platform with parallel animal processing
    • Chang, T.-Y., Pardo-Martin, C., Allalou, A., Wählby, C. & Yanik, M. F. Fully automated cellularresolution vertebrate screening platform with parallel animal processing. Lab Chip 12, 711-716 (2012).
    • (2012) Lab Chip , vol.12 , pp. 711-716
    • Chang, T.-Y.1    Pardo-Martin, C.2    Allalou, A.3    Wählby, C.4    Yanik, M.F.5
  • 74
    • 77955169046 scopus 로고    scopus 로고
    • High-throughput in vivo vertebrate screening
    • Pardo-Martin, C. et al. High-throughput in vivo vertebrate screening. Nature Publishing Group 7, 634-636(2010).
    • (2010) Nature Publishing Group , vol.7 , pp. 634-636
    • Pardo-Martin, C.1
  • 75
    • 84858688206 scopus 로고    scopus 로고
    • The SpikerBox: a low cost, open-source bioamplifier for increasing public participation in neuroscience inquiry
    • Marzullo, T. C. & Gage, G. J. The SpikerBox: a low cost, open-source bioamplifier for increasing public participation in neuroscience inquiry. PLoS ONE 7, e30837 (2012).
    • (2012) PLoS ONE , vol.7
    • Marzullo, T.C.1    Gage, G.J.2
  • 76
    • 71849088986 scopus 로고    scopus 로고
    • Biotech in the basement
    • Alper, J. Biotech in the basement. Nat. Biotechnol. 27,1077-1078 (2009).
    • (2009) Nat. Biotechnol. , vol.27 , pp. 1077-1078
    • Alper, J.1
  • 77
    • 84876267888 scopus 로고    scopus 로고
    • Towards a comprehensive catalog of zebrafish behavior 1
    • Kalueff, A. V. et al. Towards a comprehensive catalog of zebrafish behavior 1.0 and beyond. Zebrafish 10, 70-86 (2013).
    • (2013) 0 and beyond. Zebrafish , vol.10 , pp. 70-86
    • Kalueff, A.V.1
  • 78
    • 84865404610 scopus 로고    scopus 로고
    • Automated high-throughput neurophenotyping of zebrafish social behavior
    • Green, J. et al. Automated high-throughput neurophenotyping of zebrafish social behavior. J. Neurosci. Methods 210, 266-271 (2012).
    • (2012) J. Neurosci. Methods , vol.210 , pp. 266-271
    • Green, J.1
  • 79
    • 84859025663 scopus 로고    scopus 로고
    • The Zebrafish Neurophenome Database (ZND): a dynamic open-access resource for zebrafish neurophenotypic data
    • Kyzar, E. et al. The Zebrafish Neurophenome Database (ZND): a dynamic open-access resource for zebrafish neurophenotypic data. Zebrafish 9, 8-14 (2012).
    • (2012) Zebrafish , vol.9 , pp. 8-14
    • Kyzar, E.1
  • 81
    • 33845876254 scopus 로고    scopus 로고
    • The Connectivity Map: a new tool for biomedical research
    • Lamb, J. The Connectivity Map: a new tool for biomedical research. Nat. Rev. Cancer 7, 54-60 (2007).
    • (2007) Nat. Rev. Cancer , vol.7 , pp. 54-60
    • Lamb, J.1
  • 82
    • 33749335282 scopus 로고    scopus 로고
    • The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease
    • Lamb, J. et al. The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science 313,1929-1935 (2006).
    • (2006) Science , vol.313 , pp. 1929-1935
    • Lamb, J.1
  • 83
    • 84875457497 scopus 로고    scopus 로고
    • Photochemical activation of TRPA1 channels in neurons and animals
    • Kokel, D. et al. Photochemical activation of TRPA1 channels in neurons and animals. Nat. Chem. Biol. 9, 257-263 (2013).
    • (2013) Nat. Chem. Biol. , vol.9 , pp. 257-263
    • Kokel, D.1
  • 84
    • 84875652264 scopus 로고    scopus 로고
    • Optical control of metabotropic glutamate receptors
    • Levitz, J. et al. Optical control of metabotropic glutamate receptors. Nature Neuroscience 16, 507-516(2013).
    • (2013) Nature Neuroscience , vol.16 , pp. 507-516
    • Levitz, J.1
  • 85
    • 77955052419 scopus 로고    scopus 로고
    • A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing
    • Janovjak, H., Szobota, S., Wyart, C., Trauner, D. & Isacoff, E. Y. A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing. Nature Neuroscience 13,1027-1032 (2010).
    • (2010) Nature Neuroscience , vol.13 , pp. 1027-1032
    • Janovjak, H.1    Szobota, S.2    Wyart, C.3    Trauner, D.4    Isacoff, E.Y.5
  • 86
    • 34248548818 scopus 로고    scopus 로고
    • Remote control of neuronal activity with a light-gated glutamate receptor
    • Szobota, S. et al. Remote control of neuronal activity with a light-gated glutamate receptor. Neuron 54, 535-545 (2007).
    • (2007) Neuron , vol.54 , pp. 535-545
    • Szobota, S.1
  • 87
    • 84884165152 scopus 로고    scopus 로고
    • Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment
    • Baraban, S. C., Dinday, M. T. & Hortopan, G. A. Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment. Nat Comms 4, 2410 (2013).
    • (2013) Nat Comms , vol.4 , pp. 2410
    • Baraban, S.C.1    Dinday, M.T.2    Hortopan, G.A.3
  • 88
    • 84874617789 scopus 로고    scopus 로고
    • Efficient genome editing in zebrafish using a CRISPR-Cas system
    • Hwang, W. Y. et al. Efficient genome editing in zebrafish using a CRISPR-Cas system. Nat. Biotechnol. 31, 227-229 (2013).
    • (2013) Nat. Biotechnol. , vol.31 , pp. 227-229
    • Hwang, W.Y.1
  • 89
    • 84879949311 scopus 로고    scopus 로고
    • Heritable and precise zebrafish genome editing using a CRISPR-Cas system
    • Hwang, W. Y. et al. Heritable and precise zebrafish genome editing using a CRISPR-Cas system. PLoS ONE8, e68708(2013).
    • (2013) PLoS ONE8
    • Hwang, W.Y.1
  • 90
    • 84891722219 scopus 로고    scopus 로고
    • Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair
    • Auer, T. O., Duroure, K., De Cian, A., Concordet, J.-P. & Del Bene, F. Highly efficient CRISPR/Cas9-mediated knock-in in zebrafish by homology-independent DNA repair. Genome Res. 24,142-153 (2014).
    • (2014) Genome Res , vol.24 , pp. 142-153
    • Auer, T.O.1    Duroure, K.2    De Cian, A.3    Concordet, J.-P.4    Del Bene, F.5
  • 91
    • 36148960495 scopus 로고    scopus 로고
    • Generation of a transgenic zebrafish model of Tauopathy using a novel promoter element derived from the zebrafish eno2 gene
    • Bai, Q., Garver, J. A., Hukriede, N. A. & Burton, E. A. Generation of a transgenic zebrafish model of Tauopathy using a novel promoter element derived from the zebrafish eno2 gene. Nucleic Acids Res. 35, 6501-6516 (2007).
    • (2007) Nucleic Acids Res , vol.35 , pp. 6501-6516
    • Bai, Q.1    Garver, J.A.2    Hukriede, N.A.3    Burton, E.A.4
  • 92
    • 77953504727 scopus 로고    scopus 로고
    • Analysis of a zebrafish behavioral mutant reveals a dominant mutation in atp2a1/SERCA1
    • Olson, B. D., Sgourdou, P. & Downes, G. B. Analysis of a zebrafish behavioral mutant reveals a dominant mutation in atp2a1/SERCA1. Genesis 48, 354-361 (2010).
    • (2010) Genesis , vol.48 , pp. 354-361
    • Olson, B.D.1    Sgourdou, P.2    Downes, G.B.3
  • 93
    • 13844314605 scopus 로고    scopus 로고
    • Pentylenetetrazol induced changes in zebrafish behavior, neural activity and c-fos expression
    • Baraban, S. C., Taylor, M. R., Castro, P. A. & Baier, H. Pentylenetetrazol induced changes in zebrafish behavior, neural activity and c-fos expression. Neuroscience 131, 759-768 (2005).
    • (2005) Neuroscience , vol.131 , pp. 759-768
    • Baraban, S.C.1    Taylor, M.R.2    Castro, P.A.3    Baier, H.4
  • 94
    • 40749095640 scopus 로고    scopus 로고
    • Functional and developmental analysis of the blood-brain barrier in zebrafish
    • Jeong, J.-Y. et al. Functional and developmental analysis of the blood-brain barrier in zebrafish. Brain Res. Bull. 75, 619-628 (2008).
    • (2008) Brain Res. Bull , vol.75 , pp. 619-628
    • Jeong, J.-Y.1
  • 95
    • 84867302438 scopus 로고    scopus 로고
    • A call for transparent reporting to optimize the predictive value of preclinical research
    • Landis, S. C. et al. A call for transparent reporting to optimize the predictive value of preclinical research. Nature 490,187-191 (2012).
    • (2012) Nature , vol.490 , pp. 187-191
    • Landis, S.C.1
  • 96
    • 84876798186 scopus 로고    scopus 로고
    • The zebrafish reference genome sequence and its relationship to the human genome
    • Howe, K. et al. The zebrafish reference genome sequence and its relationship to the human genome. Nature 496, 498-503 (2013).
    • (2013) Nature , vol.496 , pp. 498-503
    • Howe, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.