A heterocyclic molecule kartogenin induces collagen synthesis of human dermal fibroblasts by activating the smad4/smad5 pathway

Biochemical and Biophysical Research Communications

Volumn 450, Issue 1, 2014, Pages 568-574

  Wang, Jing ^a   Zhou, Jia ^a   Zhang, Ning ^b   Zhang, Xiaoling ^a,b   Li, Qingfeng ^a  

^a SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Collagen I; Fibroblasts; Kartogenin; Smad5; Small molecule

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN; COLLAGEN TYPE 1; GELATINASE B; HETEROCYCLIC COMPOUND; INTERSTITIAL COLLAGENASE; KARTOGENIN; MESSENGER RNA; SMAD4 PROTEIN; SMAD5 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL VIABILITY; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DERMIS; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; WESTERN BLOTTING;

MUS;

COLLAGEN I; FIBROBLASTS; KARTOGENIN; SMAD5; SMALL MOLECULE;

ANILIDES; ANIMALS; CELL SURVIVAL; CELLS, CULTURED; COLLAGEN TYPE I; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; HETEROCYCLIC COMPOUNDS; HUMANS; MICE; MICE, INBRED BALB C; PHTHALIC ACIDS; SIGNAL TRANSDUCTION; SKIN; SMAD4 PROTEIN; SMAD5 PROTEIN;

EID: 84904762609     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.06.016     Document Type: Article

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