Anticancer constituents from the roots of Rubia cordifolia L.

Chemical and Pharmaceutical Bulletin

Volumn 56, Issue 2, 2008, Pages 213-216

  Son, Jong Keun ^a   Jung, Soon Ja ^b   Jung, Ji Hyun ^b   Fang, Zhe ^b   Lee, Chong Soon ^a   Seo, Chang Seob ^a   Moon, Dong Cheul ^c   Min, Byung Sun ^b   Kim, Mi Ryeo ^d   Woo, Mi Hee ^b  

^a Yeungnam University   (South Korea)

^b Catholic University of Daegu   (South Korea)

^c Chungbuk National University   (South Korea)

^d Dongguk University   (South Korea)

Author keywords

Cytotoxicity; Epoxymollugin; Rubia cordifolia L.; Topoisomerase

Indexed keywords

1 ACETOXY 3 METHOXY 9,10 ANTHRAQUINONE; 1 HYDROXY 2 METHOXY 9,10 ANTHRAQUINONE; 1,6 DIHYDROXY 2 METHYL 9,10 ANTHRAQUINONE; 2 CARBOMETHOXY 2,3 EPOXY 3 PRENYL 1,4 NAPHTHOQUINONE; 3,3' BIS(3,4 DIHYDRO 4 HYDROXY 6 METHOXY 2H 1 BENZOPYRAN); ANTINEOPLASTIC AGENT; DICHLOROMETHANE; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); EPOXYMOLLUGIN; FUROMOLLUGIN; MOLLUGIN; OLEANOLIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; ENZYME INHIBITION; HUMAN; HUMAN CELL; MEDICINAL PLANT; PLANT ROOT; RUBIA CORDIFOLIA; SPECTROSCOPY;

ANTHRAQUINONES; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; ENZYME INHIBITORS; HT29 CELLS; HUMANS; KOREA; MAGNETIC RESONANCE SPECTROSCOPY; NAPHTHOLS; PLANT ROOTS; PYRANS; RUBIA; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT; SPECTROPHOTOMETRY, ULTRAVIOLET; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 38849173874     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.56.213     Document Type: Article

References (13)

1. Itokawa H., Mihara K., Takeya K., Chem. Pharm. Bull., 31, 2353-2358 (1983).
2. Chung M. I., Jou S. J., Cheng T. H., Lin C. N., J. Nat. Prod., 57, 313-316 (1994).
3. Han B. H., Park M. K., Park Y. H., Arch. Pharm. Res., 13, 289-291 (1990).
4. Itokawa H., Qiao Y., Mihara K., Takeya K., Phytochemistry, 30, 637-640 (1991).
5. Son J. K., Jung J. H., Lee C. S., Moon D. C., Choi S. W., Min B. S., Woo M. H., Bull. Korean Chem. Soc., 27, 1231-1234 (2006).
6. Saleem R., Faizi S., Deeba F., Siddiqui B. S., Qazi M. H., Planta Med., 63, 454-456 (1997).
7. Berger Y., Castonuay A., Brassard P., Organic Magnetic Resonance, 14, 103-108 (1980).
8. Rao G. V., Rao P. S., J. Ind. Chem. Soc., 60, 585-586 (1983).
9. Banthorpe D. V., White J. J., Phytochemistry, 38, 107-111 (1995).
10. Ali A. M., Ismail N. H., Mackeen M. M., Yazan L. S., Mohamed S. M., Ho A. S. M., Lajis N. H., Pharmaceutical Biology (Lisse, Netherlands), 38, 298-301 (2000).
11. Kang S. S., Kor. J. Pharmacogn., 18, 151-167 (1987).
12. Fukuda M., Nishio K., Kanzawa H., Ogasawa H., Ishida T., Arioka H., Bojamowki K., Oka M., Sajio N., Cancer Res., 56, 789-793 (1996).
13. Rubinstein L. V., Shoemaker R. H., Boyd M. R., J. Natl. Cancer, 82, 1113-1118 (1990).