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Volumn 108, Issue 7, 2014, Pages 1137-1144

Glucose reduces the anticonvulsant effects of the ketogenic diet in EL mice

Author keywords

Calorie restriction; Epilepsy; Ketones; Seizure susceptibility

Indexed keywords

3 HYDROXYBUTYRIC ACID; DRINKING WATER; GLUCOSE; GLUCOSE BLOOD LEVEL; SWEETENING AGENT;

EID: 84904752908     PISSN: 09201211     EISSN: 18726844     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2014.05.010     Document Type: Article
Times cited : (10)

References (87)
  • 1
    • 0024330728 scopus 로고
    • Glycolysis-induced discordance between glucose metabolic rates measured with radiolabeled fluorodeoxyglucose and glucose
    • Ackermann R.F., Lear J.L. Glycolysis-induced discordance between glucose metabolic rates measured with radiolabeled fluorodeoxyglucose and glucose. J. Cereb. Blood Flow Metab. 1989, 9:774-785.
    • (1989) J. Cereb. Blood Flow Metab. , vol.9 , pp. 774-785
    • Ackermann, R.F.1    Lear, J.L.2
  • 3
    • 58649103488 scopus 로고    scopus 로고
    • The ketogenic diet: uses in epilepsy and other neurologic illnesses
    • Baranano K.W., Hartman A.L. The ketogenic diet: uses in epilepsy and other neurologic illnesses. Curr. Treat. Options Neurol. 2008, 10:410-419.
    • (2008) Curr. Treat. Options Neurol. , vol.10 , pp. 410-419
    • Baranano, K.W.1    Hartman, A.L.2
  • 4
    • 0032901064 scopus 로고    scopus 로고
    • A ketogenic diet increases the resistance to pentylenetetrazole-induced seizures in the rat
    • Bough K.J., Eagles D.A. A ketogenic diet increases the resistance to pentylenetetrazole-induced seizures in the rat. Epilepsia 1999, 40:138-143.
    • (1999) Epilepsia , vol.40 , pp. 138-143
    • Bough, K.J.1    Eagles, D.A.2
  • 5
    • 33846250398 scopus 로고    scopus 로고
    • Anticonvulsant mechanisms of the ketogenic diet
    • Bough K.J., Rho J.M. Anticonvulsant mechanisms of the ketogenic diet. Epilepsia 2007, 48:43-58.
    • (2007) Epilepsia , vol.48 , pp. 43-58
    • Bough, K.J.1    Rho, J.M.2
  • 6
    • 0026567335 scopus 로고
    • Biochemical correlates of epilepsy in the El mouse: analysis of glial fibrillary acidic protein and gangliosides
    • Brigande J.V., Wieraszko A., Albert M.D., Balkema G.W., Seyfried T.N. Biochemical correlates of epilepsy in the El mouse: analysis of glial fibrillary acidic protein and gangliosides. J. Neurochem. 1992, 58:752-760.
    • (1992) J. Neurochem. , vol.58 , pp. 752-760
    • Brigande, J.V.1    Wieraszko, A.2    Albert, M.D.3    Balkema, G.W.4    Seyfried, T.N.5
  • 7
    • 0000202516 scopus 로고    scopus 로고
    • Circulation and energy metabolism of the brain
    • Lippincott-Raven, New York, G.J. Siegel, B.W. Agranoff, R.W. Albers, S.K. Fisher, M.D. Uhler (Eds.)
    • Clarke D.D., Sokoloff L. Circulation and energy metabolism of the brain. Basic Neurochemistry: Molecular, Cellular and Medical Aspects 1999, 637-669. Lippincott-Raven, New York. 6th ed. G.J. Siegel, B.W. Agranoff, R.W. Albers, S.K. Fisher, M.D. Uhler (Eds.).
    • (1999) Basic Neurochemistry: Molecular, Cellular and Medical Aspects , pp. 637-669
    • Clarke, D.D.1    Sokoloff, L.2
  • 9
  • 10
    • 77953200616 scopus 로고    scopus 로고
    • Adverse effects of antiepileptic drugs: a brief overview of important issues
    • Cramer J.A., Mintzer S., Wheless J., Mattson R.H. Adverse effects of antiepileptic drugs: a brief overview of important issues. Expert Rev. Neurother. 2010, 10:885-891.
    • (2010) Expert Rev. Neurother. , vol.10 , pp. 885-891
    • Cramer, J.A.1    Mintzer, S.2    Wheless, J.3    Mattson, R.H.4
  • 11
    • 0242658620 scopus 로고    scopus 로고
    • Hippocampal neurons and glia in epileptic EL mice
    • Drage M.G., Holmes G.L., Seyfried T.N. Hippocampal neurons and glia in epileptic EL mice. J. Neurocytol. 2002, 31:681-692.
    • (2002) J. Neurocytol. , vol.31 , pp. 681-692
    • Drage, M.G.1    Holmes, G.L.2    Seyfried, T.N.3
  • 12
    • 0038735542 scopus 로고    scopus 로고
    • Calorie restriction of a high-carbohydrate diet elevates the threshold of PTZ-induced seizures to values equal to those seen with a ketogenic diet
    • Eagles D.A., Boyd S.J., Kotak A., Allan F. Calorie restriction of a high-carbohydrate diet elevates the threshold of PTZ-induced seizures to values equal to those seen with a ketogenic diet. Epilepsy Res. 2003, 54:41-52.
    • (2003) Epilepsy Res. , vol.54 , pp. 41-52
    • Eagles, D.A.1    Boyd, S.J.2    Kotak, A.3    Allan, F.4
  • 13
    • 0009759447 scopus 로고    scopus 로고
    • Introduction: what is epilepsy?
    • Lipponcott-Raven, New York, J.J. Englel, T.A. Pedley (Eds.)
    • Engel J.J., Pedley T.A. Introduction: what is epilepsy?. Epilepsy: A Comprehensive Textbook 1997, 1-10. Lipponcott-Raven, New York. J.J. Englel, T.A. Pedley (Eds.).
    • (1997) Epilepsy: A Comprehensive Textbook , pp. 1-10
    • Engel, J.J.1    Pedley, T.A.2
  • 14
    • 0028021849 scopus 로고
    • Enhanced aspartate release related to epilepsy in (EL) mice
    • Flavin H.J., Seyfried T.N. Enhanced aspartate release related to epilepsy in (EL) mice. J. Neurochem. 1994, 63:592-595.
    • (1994) J. Neurochem. , vol.63 , pp. 592-595
    • Flavin, H.J.1    Seyfried, T.N.2
  • 15
    • 39349102730 scopus 로고    scopus 로고
    • Calorie restriction and cardiometabolic health
    • Fontana L. Calorie restriction and cardiometabolic health. Eur. J. Cardiovasc. Prev. Rehabil. 2008, 15:3-9.
    • (2008) Eur. J. Cardiovasc. Prev. Rehabil. , vol.15 , pp. 3-9
    • Fontana, L.1
  • 16
    • 0029443328 scopus 로고
    • Congenic strains reveal effects of the epilepsy quantitative locus, El2, separate from other El loci
    • Frankel W.N., Johnson E.W., Lutz C.M. Congenic strains reveal effects of the epilepsy quantitative locus, El2, separate from other El loci. Mamm. Genome 1995, 6:839-843.
    • (1995) Mamm. Genome , vol.6 , pp. 839-843
    • Frankel, W.N.1    Johnson, E.W.2    Lutz, C.M.3
  • 22
    • 0031975075 scopus 로고    scopus 로고
    • Regional differences in hippocampal excitability manifested by paired-pulse stimulation of genetically epileptic El mice
    • Fueta Y., Kawano H., Ono T., Mita T., Fukata K., Ohno K. Regional differences in hippocampal excitability manifested by paired-pulse stimulation of genetically epileptic El mice. Brain Res. 1998, 779:324-328.
    • (1998) Brain Res. , vol.779 , pp. 324-328
    • Fueta, Y.1    Kawano, H.2    Ono, T.3    Mita, T.4    Fukata, K.5    Ohno, K.6
  • 23
    • 33748298884 scopus 로고    scopus 로고
    • Neuroprotective and disease-modifying effects of the ketogenic diet
    • Gasior M., Rogawski M.A., Hartman A.L. Neuroprotective and disease-modifying effects of the ketogenic diet. Behav. Pharmacol. 2006, 17:431-439.
    • (2006) Behav. Pharmacol. , vol.17 , pp. 431-439
    • Gasior, M.1    Rogawski, M.A.2    Hartman, A.L.3
  • 24
    • 0041803018 scopus 로고    scopus 로고
    • Perspectives on the metabolic management of epilepsy through dietary reduction of glucose and elevation of ketone bodies
    • Greene A.E., Todorova M.M., Seyfried T.N. Perspectives on the metabolic management of epilepsy through dietary reduction of glucose and elevation of ketone bodies. J. Neurochem. 2003, 86:529-537.
    • (2003) J. Neurochem. , vol.86 , pp. 529-537
    • Greene, A.E.1    Todorova, M.M.2    Seyfried, T.N.3
  • 25
    • 0035213616 scopus 로고    scopus 로고
    • Caloric restriction inhibits seizure susceptibility in epileptic EL mice by reducing blood glucose
    • Greene A.E., Todorova M.T., McGowan R., Seyfried T.N. Caloric restriction inhibits seizure susceptibility in epileptic EL mice by reducing blood glucose. Epilepsia 2001, 42:1371-1378.
    • (2001) Epilepsia , vol.42 , pp. 1371-1378
    • Greene, A.E.1    Todorova, M.T.2    McGowan, R.3    Seyfried, T.N.4
  • 26
    • 33947264635 scopus 로고    scopus 로고
    • Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease
    • Halagappa V.K., Guo Z., Pearson M., Matsuoka Y., Cutler R.G., Laferla F.M., Mattson M.P. Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease. Neurobiol. Dis. 2007, 26:212-220.
    • (2007) Neurobiol. Dis. , vol.26 , pp. 212-220
    • Halagappa, V.K.1    Guo, Z.2    Pearson, M.3    Matsuoka, Y.4    Cutler, R.G.5    Laferla, F.M.6    Mattson, M.P.7
  • 28
    • 84876983403 scopus 로고    scopus 로고
    • Intermittent fasting: a new historical strategy for controlling seizures?
    • Hartman A.L., Rubenstein J.E., Kossoff E.H. Intermittent fasting: a new historical strategy for controlling seizures?. Epilepsy Res. 2013, 104:275-279.
    • (2013) Epilepsy Res. , vol.104 , pp. 275-279
    • Hartman, A.L.1    Rubenstein, J.E.2    Kossoff, E.H.3
  • 29
    • 0001490624 scopus 로고
    • Eight years' experience with the ketogenic diet in the treatment of epilepsy
    • Helmholz H.F., Keith H.M. Eight years' experience with the ketogenic diet in the treatment of epilepsy. JAMA 1930, 95:707-709.
    • (1930) JAMA , vol.95 , pp. 707-709
    • Helmholz, H.F.1    Keith, H.M.2
  • 30
    • 0034794648 scopus 로고    scopus 로고
    • The ketogenic diet: a 3- to 6-year follow-up of 150 children enrolled prospectively
    • Hemingway C., Freeman J.M., Pillas D.J., Pyzik P.L. The ketogenic diet: a 3- to 6-year follow-up of 150 children enrolled prospectively. Pediatrics 2001, 108:898-905.
    • (2001) Pediatrics , vol.108 , pp. 898-905
    • Hemingway, C.1    Freeman, J.M.2    Pillas, D.J.3    Pyzik, P.L.4
  • 31
    • 0017143254 scopus 로고
    • Ketonemia and seizures: metabolic and anticonvulsant effects of two ketogenic diets in childhood epilepsy
    • Huttenlocher P.R. Ketonemia and seizures: metabolic and anticonvulsant effects of two ketogenic diets in childhood epilepsy. Pediatr. Res. 1976, 10:536-540.
    • (1976) Pediatr. Res. , vol.10 , pp. 536-540
    • Huttenlocher, P.R.1
  • 32
    • 0037458584 scopus 로고    scopus 로고
    • Glycolysis and glutamate accumulation into synaptic vesicles. Role of glyceraldehyde phosphate dehydrogenase and 3-phosphoglycerate kinase
    • Ikemoto A., Bole D.G., Ueda T. Glycolysis and glutamate accumulation into synaptic vesicles. Role of glyceraldehyde phosphate dehydrogenase and 3-phosphoglycerate kinase. J. Biol. Chem. 2003, 278:5929-5940.
    • (2003) J. Biol. Chem. , vol.278 , pp. 5929-5940
    • Ikemoto, A.1    Bole, D.G.2    Ueda, T.3
  • 33
    • 0027477694 scopus 로고
    • Epileptic seizure of El mouse initiates at the parietal cortex: depth EEG observation in freely moving condition using buffer amplifier
    • Ishida N., Kasamo K., Nakamoto Y., Suzuki J. Epileptic seizure of El mouse initiates at the parietal cortex: depth EEG observation in freely moving condition using buffer amplifier. Brain Res. 1993, 608:52-57.
    • (1993) Brain Res. , vol.608 , pp. 52-57
    • Ishida, N.1    Kasamo, K.2    Nakamoto, Y.3    Suzuki, J.4
  • 34
    • 84891982870 scopus 로고    scopus 로고
    • Epilepsy: a general overview
    • Springer-Verlag, New York, LLC, V.P. Prasher, M.P. Kerr (Eds.)
    • Johnston A., Smith P. Epilepsy: a general overview. Epilepsy and Intellectual Disabilities 2008, 7-29. Springer-Verlag, New York, LLC. V.P. Prasher, M.P. Kerr (Eds.).
    • (2008) Epilepsy and Intellectual Disabilities , pp. 7-29
    • Johnston, A.1    Smith, P.2
  • 35
    • 4544238051 scopus 로고    scopus 로고
    • Early- and late-onset complications of the ketogenic diet for intractable epilepsy
    • Kang H.C., Chung da E., Kim D.W., Kim H.D. Early- and late-onset complications of the ketogenic diet for intractable epilepsy. Epilepsia 2004, 45:1116-1123.
    • (2004) Epilepsia , vol.45 , pp. 1116-1123
    • Kang, H.C.1    Chung da, E.2    Kim, D.W.3    Kim, H.D.4
  • 37
    • 62949137030 scopus 로고    scopus 로고
    • Ketogenic diets: evidence for short- and long-term efficacy
    • Kossoff E.H., Rho J.M. Ketogenic diets: evidence for short- and long-term efficacy. Neurotherapeutics 2009, 6:406-414.
    • (2009) Neurotherapeutics , vol.6 , pp. 406-414
    • Kossoff, E.H.1    Rho, J.M.2
  • 39
    • 0030557803 scopus 로고    scopus 로고
    • Analysis of the kinetics of synaptic inhibition points to a reduction in GABA release in area CA1 of the genetically epileptic mouse, El
    • Lambert J.D., Fueta Y., Roepstorff A., Andreasen M. Analysis of the kinetics of synaptic inhibition points to a reduction in GABA release in area CA1 of the genetically epileptic mouse, El. Epilepsy Res. 1996, 26:15-23.
    • (1996) Epilepsy Res. , vol.26 , pp. 15-23
    • Lambert, J.D.1    Fueta, Y.2    Roepstorff, A.3    Andreasen, M.4
  • 41
    • 84873686589 scopus 로고    scopus 로고
    • Metabolic and neuropsychiatric effects of calorie restriction and sirtuins
    • Libert S., Guarente L. Metabolic and neuropsychiatric effects of calorie restriction and sirtuins. Annu. Rev. Physiol. 2013, 75:669-684.
    • (2013) Annu. Rev. Physiol. , vol.75 , pp. 669-684
    • Libert, S.1    Guarente, L.2
  • 44
    • 84871718480 scopus 로고    scopus 로고
    • The ketogenic diet: metabolic influences on brain excitability and epilepsy
    • Lutas A., Yellen G. The ketogenic diet: metabolic influences on brain excitability and epilepsy. Trends Neurosci. 2013, 36:32-40.
    • (2013) Trends Neurosci. , vol.36 , pp. 32-40
    • Lutas, A.1    Yellen, G.2
  • 45
    • 15444371484 scopus 로고    scopus 로고
    • Management of multifactorial idiopathic epilepsy in EL mice with caloric restriction and the ketogenic diet: role of glucose and ketone bodies
    • Mantis J.G., Centeno N.A., Todorova M.T., McGowan R., Seyfried T.N. Management of multifactorial idiopathic epilepsy in EL mice with caloric restriction and the ketogenic diet: role of glucose and ketone bodies. Nutr. Metab. 2004, 1:11.
    • (2004) Nutr. Metab. , vol.1 , pp. 11
    • Mantis, J.G.1    Centeno, N.A.2    Todorova, M.T.3    McGowan, R.4    Seyfried, T.N.5
  • 46
    • 67349261223 scopus 로고    scopus 로고
    • Improvement in motor and exploratory behavior in Rett syndrome mice with restricted ketogenic and standard diets
    • Mantis J.G., Fritz C.L., Marsh J., Heinrichs S.C., Seyfried T.N. Improvement in motor and exploratory behavior in Rett syndrome mice with restricted ketogenic and standard diets. Epilepsy Behav. 2009, 15:133-141.
    • (2009) Epilepsy Behav. , vol.15 , pp. 133-141
    • Mantis, J.G.1    Fritz, C.L.2    Marsh, J.3    Heinrichs, S.C.4    Seyfried, T.N.5
  • 48
    • 33645297386 scopus 로고    scopus 로고
    • The outcome of children with intractable seizures: a 3- to 6-year follow-up of 67 children who remained on the ketogenic diet less than one year
    • Marsh E.B., Freeman J.M., Kossoff E.H., Vining E.P., Rubenstein J.E., Pyzik P.L., Hemingway C. The outcome of children with intractable seizures: a 3- to 6-year follow-up of 67 children who remained on the ketogenic diet less than one year. Epilepsia 2006, 47:425-430.
    • (2006) Epilepsia , vol.47 , pp. 425-430
    • Marsh, E.B.1    Freeman, J.M.2    Kossoff, E.H.3    Vining, E.P.4    Rubenstein, J.E.5    Pyzik, P.L.6    Hemingway, C.7
  • 49
    • 58149175598 scopus 로고    scopus 로고
    • Akt-dependent proapoptotic effects of dietary restriction on late-stage management of a phosphatase and tensin homologue/tuberous sclerosis complex 2-deficient mouse astrocytoma
    • Marsh J., Mukherjee P., Seyfried T.N. Akt-dependent proapoptotic effects of dietary restriction on late-stage management of a phosphatase and tensin homologue/tuberous sclerosis complex 2-deficient mouse astrocytoma. Clin. Cancer Res. 2008, 14:7751-7762.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 7751-7762
    • Marsh, J.1    Mukherjee, P.2    Seyfried, T.N.3
  • 51
    • 79951593809 scopus 로고    scopus 로고
    • The EL mouse: a natural model of autism and epilepsy
    • Meidenbauer J.J., Mantis J.G., Seyfried T.N. The EL mouse: a natural model of autism and epilepsy. Epilepsia 2011, 52:347-357.
    • (2011) Epilepsia , vol.52 , pp. 347-357
    • Meidenbauer, J.J.1    Mantis, J.G.2    Seyfried, T.N.3
  • 52
    • 0006849524 scopus 로고    scopus 로고
    • Epileptic seizures and epilepsy
    • Lippincott-Raven, New York, G.J. Siegel, B.W. Agranoff, R.W. Albers, S.K. Fisher, M.D. Uhler (Eds.)
    • Meldrum B., Chapman A. Epileptic seizures and epilepsy. Basic Neurochemistry: Molecular, Cellular and Medical Aspects 1999, 755-768. Lippincott-Raven, New York. 6th ed. G.J. Siegel, B.W. Agranoff, R.W. Albers, S.K. Fisher, M.D. Uhler (Eds.).
    • (1999) Basic Neurochemistry: Molecular, Cellular and Medical Aspects , pp. 755-768
    • Meldrum, B.1    Chapman, A.2
  • 53
    • 21844434180 scopus 로고    scopus 로고
    • Developmental program of epileptogenesis in the brain of EL mice
    • Murashima Y.L., Suzuki J., Yoshii M. Developmental program of epileptogenesis in the brain of EL mice. Epilepsia 2005, 46(Suppl. 5):10-16.
    • (2005) Epilepsia , vol.46 , Issue.SUPPL. 5 , pp. 10-16
    • Murashima, Y.L.1    Suzuki, J.2    Yoshii, M.3
  • 54
    • 0027981636 scopus 로고
    • Chronic implantation technique for monopolar EEG monitoring of epileptic seizures in mice
    • Nakano H., Saito K., Suzuki K. Chronic implantation technique for monopolar EEG monitoring of epileptic seizures in mice. Brain Res. Bull. 1994, 35:261-268.
    • (1994) Brain Res. Bull. , vol.35 , pp. 261-268
    • Nakano, H.1    Saito, K.2    Suzuki, K.3
  • 55
    • 0001929595 scopus 로고
    • The beginnings of studies on EL mice
    • Naruse H., Kurokawa M. The beginnings of studies on EL mice. Neurosciences 1992, 18(Suppl. 2):1-3.
    • (1992) Neurosciences , vol.18 , Issue.SUPPL. 2 , pp. 1-3
    • Naruse, H.1    Kurokawa, M.2
  • 57
    • 0027294367 scopus 로고
    • Glucose and ketone body utilization by the brain of neonatal rats
    • Nehlig A., Pereira de Vasconcelos A. Glucose and ketone body utilization by the brain of neonatal rats. Prog. Neurobiol. 1993, 40:163-221.
    • (1993) Prog. Neurobiol. , vol.40 , pp. 163-221
    • Nehlig, A.1    Pereira de Vasconcelos, A.2
  • 61
    • 38649105197 scopus 로고    scopus 로고
    • Calorie-restricted ketogenic diet increases thresholds to all patterns of pentylenetetrazol-induced seizures: critical importance of electroclinical assessment
    • Raffo E., Francois J., Ferrandon A., Koning E., Nehlig A. Calorie-restricted ketogenic diet increases thresholds to all patterns of pentylenetetrazol-induced seizures: critical importance of electroclinical assessment. Epilepsia 2008, 49:320-328.
    • (2008) Epilepsia , vol.49 , pp. 320-328
    • Raffo, E.1    Francois, J.2    Ferrandon, A.3    Koning, E.4    Nehlig, A.5
  • 62
    • 0036214170 scopus 로고    scopus 로고
    • Acetoacetate, acetone, and dibenzylamine (a contaminant in l-(+)-beta-hydroxybutyrate) exhibit direct anticonvulsant actions in vivo
    • Rho J.M., Anderson G.D., Donevan S.D., White H.S. Acetoacetate, acetone, and dibenzylamine (a contaminant in l-(+)-beta-hydroxybutyrate) exhibit direct anticonvulsant actions in vivo. Epilepsia 2002, 43:358-361.
    • (2002) Epilepsia , vol.43 , pp. 358-361
    • Rho, J.M.1    Anderson, G.D.2    Donevan, S.D.3    White, H.S.4
  • 64
    • 0001699915 scopus 로고    scopus 로고
    • Overview of the current animal models for human seizure and epileptic disorders
    • Sarkisian M.R. Overview of the current animal models for human seizure and epileptic disorders. Epilepsy Behav. 2001, 2:201-216.
    • (2001) Epilepsy Behav. , vol.2 , pp. 201-216
    • Sarkisian, M.R.1
  • 65
    • 0022333456 scopus 로고
    • The development of EEG background activities in El mouse
    • Sato H. The development of EEG background activities in El mouse. Folia Psychiatr. Neurol. Jpn. 1985, 39:581-587.
    • (1985) Folia Psychiatr. Neurol. Jpn. , vol.39 , pp. 581-587
    • Sato, H.1
  • 66
    • 0037231770 scopus 로고    scopus 로고
    • Correlation between extracellular glucose and seizure susceptibility in adult rats
    • Schwechter E.M., Veliskova J., Velisek L. Correlation between extracellular glucose and seizure susceptibility in adult rats. Ann. Neurol. 2003, 53:91-101.
    • (2003) Ann. Neurol. , vol.53 , pp. 91-101
    • Schwechter, E.M.1    Veliskova, J.2    Velisek, L.3
  • 68
    • 0006973716 scopus 로고    scopus 로고
    • Genetics of the EL mouse: a multifactorial epilepsy model
    • J. Libby, London, P. Genton, S.F. Berkovic, E. Hirsch, C. Marescaux (Eds.)
    • Seyfried T.N., Poderycki M.J., Todorova M.T. Genetics of the EL mouse: a multifactorial epilepsy model. Genetics of Focal Epilepsies 1999, 229-238. J. Libby, London. P. Genton, S.F. Berkovic, E. Hirsch, C. Marescaux (Eds.).
    • (1999) Genetics of Focal Epilepsies , pp. 229-238
    • Seyfried, T.N.1    Poderycki, M.J.2    Todorova, M.T.3
  • 69
    • 62749131214 scopus 로고    scopus 로고
    • Life span extension in mice by food restriction depends on an energy imbalance
    • Sohal R.S., Ferguson M., Sohal B.H., Forster M.J. Life span extension in mice by food restriction depends on an energy imbalance. J. Nutr. 2009, 139:533-539.
    • (2009) J. Nutr. , vol.139 , pp. 533-539
    • Sohal, R.S.1    Ferguson, M.2    Sohal, B.H.3    Forster, M.J.4
  • 70
    • 84866022656 scopus 로고    scopus 로고
    • The ketogenic diet as a treatment paradigm for diverse neurological disorders
    • Stafstrom C.E., Rho J.M. The ketogenic diet as a treatment paradigm for diverse neurological disorders. Front. Pharm. 2012, 3:59.
    • (2012) Front. Pharm. , vol.3 , pp. 59
    • Stafstrom, C.E.1    Rho, J.M.2
  • 71
    • 0017251432 scopus 로고
    • Paroxysmal discharges in the electroencephalogram of the El mouse
    • Suzuki J. Paroxysmal discharges in the electroencephalogram of the El mouse. Experientia 1976, 32:336-338.
    • (1976) Experientia , vol.32 , pp. 336-338
    • Suzuki, J.1
  • 72
    • 10644233029 scopus 로고    scopus 로고
    • Investigations of epilepsy with a mutant animal (EL mouse) model
    • Suzuki J. Investigations of epilepsy with a mutant animal (EL mouse) model. Epilepsia 2004, 45(Suppl. 8):2-5.
    • (2004) Epilepsia , vol.45 , Issue.SUPPL. 8 , pp. 2-5
    • Suzuki, J.1
  • 74
  • 75
    • 7944233055 scopus 로고    scopus 로고
    • Genetic association studies in epilepsy: the truth is out there
    • Tan N.C., Mulley J.C., Berkovic S.F. Genetic association studies in epilepsy: the truth is out there. Epilepsia 2004, 45:1429-1442.
    • (2004) Epilepsia , vol.45 , pp. 1429-1442
    • Tan, N.C.1    Mulley, J.C.2    Berkovic, S.F.3
  • 76
    • 0032796428 scopus 로고    scopus 로고
    • Environmental risk factors for multifactorial epilepsy in EL mice
    • Todorova M.T., Burwell T.J., Seyfried T.N. Environmental risk factors for multifactorial epilepsy in EL mice. Epilepsia 1999, 40:1697-1707.
    • (1999) Epilepsia , vol.40 , pp. 1697-1707
    • Todorova, M.T.1    Burwell, T.J.2    Seyfried, T.N.3
  • 77
    • 0038003809 scopus 로고    scopus 로고
    • Sexual dysfunction and sudden death in epileptic male EL mice: inheritance and prevention with the ketogenic diet
    • Todorova M.T., Dangler C.A., Drage M.G., Sheppard B.J., Fox J.G., Seyfried T.N. Sexual dysfunction and sudden death in epileptic male EL mice: inheritance and prevention with the ketogenic diet. Epilepsia 2003, 44:25-31.
    • (2003) Epilepsia , vol.44 , pp. 25-31
    • Todorova, M.T.1    Dangler, C.A.2    Drage, M.G.3    Sheppard, B.J.4    Fox, J.G.5    Seyfried, T.N.6
  • 78
    • 33748865168 scopus 로고    scopus 로고
    • Genetic and environmental interactions determine seizure susceptibility in epileptic EL mice
    • Todorova M.T., Mantis J.G., Le M., Kim C.Y., Seyfried T.N. Genetic and environmental interactions determine seizure susceptibility in epileptic EL mice. Genes Brain Behav. 2006, 5:518-527.
    • (2006) Genes Brain Behav. , vol.5 , pp. 518-527
    • Todorova, M.T.1    Mantis, J.G.2    Le, M.3    Kim, C.Y.4    Seyfried, T.N.5
  • 79
    • 0033878303 scopus 로고    scopus 로고
    • The ketogenic diet inhibits epileptogenesis in EL mice: a genetic model for idiopathic epilepsy
    • Todorova M.T., Tandon P., Madore R.A., Stafstrom C.E., Seyfried T.N. The ketogenic diet inhibits epileptogenesis in EL mice: a genetic model for idiopathic epilepsy. Epilepsia 2000, 41:933-940.
    • (2000) Epilepsia , vol.41 , pp. 933-940
    • Todorova, M.T.1    Tandon, P.2    Madore, R.A.3    Stafstrom, C.E.4    Seyfried, T.N.5
  • 80
    • 0037198393 scopus 로고    scopus 로고
    • Foci identification of spike discharges in the EEGs of sleeping El mice based on the electric field model and wavelet decomposition of multi monopolar derivations
    • Uchibori M., Saito K., Yokoyama S., Sakamoto Y., Suzuki H., Tsuji T., Suzuki K. Foci identification of spike discharges in the EEGs of sleeping El mice based on the electric field model and wavelet decomposition of multi monopolar derivations. J. Neurosci. Methods 2002, 117:51-63.
    • (2002) J. Neurosci. Methods , vol.117 , pp. 51-63
    • Uchibori, M.1    Saito, K.2    Yokoyama, S.3    Sakamoto, Y.4    Suzuki, H.5    Tsuji, T.6    Suzuki, K.7
  • 82
    • 84904735577 scopus 로고    scopus 로고
    • Adverse effects of antiepileptic drugs
    • John Wiley & Sons, Ltd, Chichester, UK, J.W. Wheless (Ed.)
    • Wheless J.W. Adverse effects of antiepileptic drugs. Epilepsy in Children and Adolescents 2013, John Wiley & Sons, Ltd, Chichester, UK. J.W. Wheless (Ed.).
    • (2013) Epilepsy in Children and Adolescents
    • Wheless, J.W.1
  • 83
    • 0001544644 scopus 로고
    • The effects of ketonemia on the course of epilepsy
    • Wilder R. The effects of ketonemia on the course of epilepsy. Mayo Clin. Proc. 1921, 2:307-308.
    • (1921) Mayo Clin. Proc. , vol.2 , pp. 307-308
    • Wilder, R.1
  • 84
    • 9044249405 scopus 로고
    • Enzymatic determination of d(-)-b-hydroxybutyric acid and acetoacetic acid in blood
    • Williamson D.H., Mellanby J., Krebs H.A. Enzymatic determination of d(-)-b-hydroxybutyric acid and acetoacetic acid in blood. J. Biochem. 1962, 82:90-96.
    • (1962) J. Biochem. , vol.82 , pp. 90-96
    • Williamson, D.H.1    Mellanby, J.2    Krebs, H.A.3
  • 85
    • 0017226070 scopus 로고
    • General anaesthesia for a patient with progressive muscular dystrophy
    • Yamashita M., Matsuki A., Oyama T. General anaesthesia for a patient with progressive muscular dystrophy. Der Anaesthesist 1976, 25:76-79.
    • (1976) Der Anaesthesist , vol.25 , pp. 76-79
    • Yamashita, M.1    Matsuki, A.2    Oyama, T.3
  • 87
    • 33847780073 scopus 로고    scopus 로고
    • The calorically restricted ketogenic diet, an effective alternative therapy for malignant brain cancer
    • Zhou W., Mukherjee P., Kiebish M.A., Markis W.T., Mantis J.G., Seyfried T.N. The calorically restricted ketogenic diet, an effective alternative therapy for malignant brain cancer. Nutr. Metab. 2007, 4:5.
    • (2007) Nutr. Metab. , vol.4 , pp. 5
    • Zhou, W.1    Mukherjee, P.2    Kiebish, M.A.3    Markis, W.T.4    Mantis, J.G.5    Seyfried, T.N.6


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