Evaluation of the efficacy of a new modified live Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) vaccine (Fostera PRRS) against heterologous PRRSV challenge

Veterinary Microbiology

Volumn 172, Issue 3-4, 2014, Pages 432-442

  Park, Changhoon ^a   Seo, Hwi Won ^a   Han, Kiwon ^a   Kang, Ikjae ^a   Chae, Chanhee ^a  

^a Seoul National University   (South Korea)

Author keywords

Modified live PRRSV vaccine; Porcine reproductive and respiratory syndrome virus; Respiratory disease; Vaccine efficacy

Indexed keywords

FOSTERA PRRS; GAMMA INTERFERON; IMMUNOGLOBULIN G ANTIBODY; INTERLEUKIN 10; NEUTRALIZING ANTIBODY; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS VACCINE; UNCLASSIFIED DRUG; VIRUS VACCINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFICACY; ENZYME LINKED IMMUNOSPOT ASSAY; FEVER; FLOW CYTOMETRY; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; INTERSTITIAL PNEUMONIA; LUNG LESION; LYMPHOCYTE SUBPOPULATION; NONHUMAN; NOSE SMEAR; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME; SECRETORY CELL; TISSUE CULTURE; VACCINATION; VIRUS ISOLATION; VIRUS STRAIN;

PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; SUIDAE;

MODIFIED LIVE PRRSV VACCINE; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS; RESPIRATORY DISEASE; VACCINE EFFICACY;

ADMINISTRATION, INTRANASAL; ANIMALS; ANTIBODIES, VIRAL; PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; SWINE; VACCINES, ATTENUATED; VIRAL VACCINES; VIREMIA;

EID: 84904752033     PISSN: 03781135     EISSN: 18732542     Source Type: Journal    
DOI: 10.1016/j.vetmic.2014.05.030     Document Type: Article

References (40)

1. Bautista E.M., Molitor T.W. IFN gamma inhibits porcine reproductive and respiratory syndrome virus replication in macrophages. Arch. Virol. 1999, 144:1191-1200.
2. Beaver B.V., Reed W., Leary S., McKiernan B., Bain F., Schultz R., Bennet B.T., Pascoe P., Shull E., Cork L.C., Francis-Loyd R., Amass K.D., Johnson R., Schmidt R.H., Underwood W., Thornton G.W., Kohn B. 2000 report of the AVMA panel on euthanasia. J. Am. Vet. Med. Assoc. 2001, 218:669-696.
3. Cavanagh D. Nidovirales: a new order comprising Coronaviridae and Arteriviridae. Arch. Virol. 1997, 142:629-633.
4. Charerntantanakul W., Platt R., Johnson W., Roof M., Vaughn E., Roth J.A. Immune responses and protection by vaccine and various vaccine adjuvant candidates to virulent porcine reproductive and respiratory syndrome virus. Vet. Immunol. Immunopathol. 2006, 109:99-115.
5. Chung W.B., Chan W.H., Chaung H.C., Lien Y., Wu C.C., Huang Y.L. Real-time PCR for quantitation of porcine reproductive and respiratory syndrome virus and porcine circovirus type 2 in naturally-infected and challenged pigs. J. Virol. Methods 2005, 124:11-19.
6. Corzo C.A., Mondaca E., Wayne S., Torremorell M., Dee S., Davies P., Morrison R.B. Control and elimination of porcine reproductive and respiratory syndrome virus. Virus Res. 2010, 154:185-192.
7. Diaz I., Darwich L., Pappaterra G., Pujols J., Mateu E. Different European-type vaccines against porcine reproductive and respiratory syndrome virus have different immunological properties and confer different protection to pigs. Virology 2006, 351:249-259.
8. Diaz I., Darwich L., Pappaterra G., Pujols J., Mateu E. Immune responses of pigs after experimental infection with a European strain of porcine reproductive and respiratory syndrome virus. J. Gen. Virol. 2005, 86:1943-1951.
9. Diaz I., Mateu E. Use of ELISPOT and ELISA to evaluate IFN-gamma, IL-10 and IL-4 responses in conventional pigs. Vet. Immunol. Immunopathol. 2005, 106:107-112.
10. Ferrari L., Martelli P., Saleri R., De Angelis E., Cavalli V., Bresaola M., Benetti M., Borghetti P. Lymphocyte activation as cytokine gene expression and secretion is related to the porcine reproductive and respiratory syndrome virus (PRRSV) isolate after in vitro homologous and heterologous recall of peripheral blood mononuclear cells (PBMC) from pigs vaccinated and exposed to natural infection. Vet. Immunol. Immunopathol. 2013, 151:193-206.
11. Gillespie T.G., Carroll A.L. Methods of control and elimination of porcine reproductive and respiratory syndrome virus using modified live vaccine in a two-site production system. J. Swine Health Prod. 2003, 11:291-295.
12. Halbur P.G., Paul P.S., Frey M.L., Landgraf J., Eernisse K., Meng X.-J., Andrews J.J., Lum M.A., Rathje J.A. Comparison of the antigen distribution of two US porcine reproductive and respiratory syndrome virus isolates with that of the Lelystad virus. Vet. Pathol. 1996, 33:159-170.
13. Halbur P.G., Paul P.S., Meng X.-J., Lum M.A., Andrews J.J., Rathje J.A. Comparative pathogenicity of nine US porcine reproductive and respiratory syndrome virus (PRRSV) isolates in a five-week-old cesarean-derived, colostrums-deprived pig model. J. Vet. Diagn. Invest. 1996, 8:11-20.
14. Halbur P.G., Paul P.S., Frey M.L., Landgraf J., Eernisse K., Meng X.-J., Lum M.A., Andrews J.J., Rathje J.A. Comparison of the pathogenicity of two US porcine reproductive and respiratory syndrome virus isolates with that of the Lelystad virus. Vet. Pathol. 1995, 32:648-660.
15. Han K., Seo H.W., Oh Y., Kang I., Park C., Chae C. Comparison of the virulence of European and North American genotypes of porcine reproductive and respiratory syndrome virus in experimentally infected pigs. Vet. J. 2013, 195:313-318.
16. Han K., Seo H.W., Oh Y., Kang I., Park C., Kang S.H., Kim S.H., Lee B.H., Kwon B., Chae C. Evaluation of monoclonal antibody-based immunohistochemistry for the detection of European and North American Porcine reproductive and respiratory syndrome virus and a comparison with in situ hybridization and reverse transcription polymerase chain reaction. J. Vet. Diagn. Invest. 2012, 24:719-724.
17. Kimman T.G., Cornelissen L.A., Moormann R.J., Rebel J.M.J., Stockhofe-Zurwieden N. Challenges for porcine reproductive and respiratory syndrome virus (PRRSV) vaccinology. Vaccine 2009, 27:3704-3718.
18. Labarque G., Nauwynck H.J., van Woensel P.A.M., Visser N., Pensaert M.B. Efficacy of an American and a European serotype PRRSV vaccine after challenge with American and European wild-type strains of the virus. Vet. Res. 2000, 31:97.
19. Labarque G., Van Gucht S., Van Reeth K., Nauwynck H., Pensaert M. Respiratory tract protection upon challenge of pigs vaccinated with attenuated porcine reproductive and respiratory syndrome virus vaccines. Vet. Microbiol. 2003, 95:187-197.
20. Labarque G., Van Reeth K., Nauwynck H., Drexler C., Van Gucht S., Pensaert M. Impact of genetic diversity of European-type porcine reproductive and respiratory syndrome virus strains on vaccine efficacy. Vaccine 2004, 22:4183-4190.
21. Mateu E., Diaz I. The challenge of PRRS immunology. Vet. J. 2008, 177:345-351.
22. Meier W.A., Galeota J., Osorio F.A., Husmann R.J., Schnitzlein W.M., Zuckermann F.A. Gradual development of the interferon-gamma response of swine to porcine reproductive and respiratory syndrome virus infection or vaccination. Virology 2003, 309:18-31.
23. Mengeling W.L., Lager K.M., Vorwald A.C., Clouser D.F. Comparative safety and efficacy of attenuated single-strain and multi-strain vaccines for porcine reproductive and respiratory syndrome virus. Vet. Microbiol. 2003, 93:25-38.
24. Mengeling W.L., Lager K.M., Vorwald A.C. Safety and efficacy of vaccination of preganant gilts against porcine reproductive and respiratory syndrome. Am. J. Vet. Res. 1999, 60:796-801.
25. Murtaugh M.P., Genzow M. Immunological solutions for treatment and prevention of porcine reproductive and respiratory syndrome (PRRS). Vaccine 2011, 29:8192-8204.
26. Nelson E.A., Christopher-Hennings J., Benfield D.A. Serum immune responses to the proteins of porcine reproductive and respiratory syndrome (PRRS) virus. J. Vet. Diagn. Invest. 1994, 6:410-415.
27. Neumann E.J., Kliebenstein J.B., Johnson C.D., Mabry J.W., Bush E.J., Seitzinger A.H., Green A.L., Zimmerman J.J. Assessment of the economic impact of porcine reproductive and respiratory syndrome on swine production in the United States. J. Am. Vet. Med. Assoc. 2005, 227:385-392.
28. Oleksiewicz M.B., Bøtner A., Madsen K.G., Storgaard T. Sensitive detection and typing of porcine reproductive and respiratory syndrome virus by RT-PCR amplification of whole viral genes. Vet. Microbiol. 1998, 64:7-22.
29. Park C., Oh Y., Seo H.W., Han K., Chae C. Comparative effects of vaccination against porcine circovirus type 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) in a PCV2-PRRSV challenge model. Clin. Vaccine Immunol. 2013, 20:369-376.
30. Prieto C., Alvarez E., Martinez-Lobo F.J., Simarro I., Castro J.M. Similarity of European porcine reproductive and respiratory syndrome virus to vaccine strain is not necessarily predictive of the degree of protective immunity conferred. Vet. J. 2008, 175:356-363.
31. Roca M., Gimeno M., Bruguera S., Segalés J., Díaz I., Galindo-Cardiel I.J., Martínez E., Darwich L., Fang Y., Maldonado J., March R., Mateu E. Effect of challenge with a virulent genotype II strain of porcine reproductive and respiratory syndrome virus on piglets vaccinated with an attenuated genotype I strain vaccine. Vet. J. 2012, 193:92-96.
32. Rowland R.R., Robinson B., Stefanick J., Kim T.S., Guanghua L., Lawson S.R., Benfield D.A. Inhibition of porcine reproductive and respiratory syndrome virus by interferon-gamma and recovery of virus replication with 2-aminopurine. Arch. Virol. 2001, 146:539-555.
33. Shi M., Lam T.T.-Y., Hon C.-C., Murtaugh M.P., Davies P.R., Hui R.K.-H., Li J., Wong L.T.-W., Yip C.-W., Jiang J.-W., Leung F.C.-C. Phylogeny-based evolutionary, demographical, and geographical dissection of North American type 2 porcine reproductive and respiratory syndrome viruses. J. Virol. 2010, 84:8700-8711.
34. Suradhat S., Thanawongnuwech R., Poovorawan Y. Upregulation of IL-10 gene expression in porcine peripheral mononuclear cells by porcine reproductive and respiratory syndrome virus. J. Gen. Virol. 2003, 84:453-459.
35. Thoresen M., Simmonds M., Satas S., Tooley J., Silver I. Effective selective head cooling during posthyposic hypothermia in newborn piglets. Pediat. Res. 2001, 49:594-599.
36. van Woensel P.A.M., Liefkens K., Demaret S. Effect on viraemia of an American and a European serotype PRRSV vaccine after challenge with European wild-type strains of the virus. Vet. Rec. 1998, 142:510-512.
37. Wasilk A., Callahan J.D., Christopher-Hennings J., Gay T.A., Fang Y., Dammen M., Reos M.E., Torremorell M., Polson D., Mellencamp M., Nelson E., Nelson W.M. Detection of U.S., Lelystad, and European-like porcine reproductive and respiratory syndrome viruses and relative quantitation in boar semen and serum samples by real-time PCR. J. Clin. Microbiol. 2004, 42:4453-4461.
38. Yoon I.J., Joo H.S., Goyal S.M., Molitor T.W. A modified serum neutralization test for the detection of antibody to porcine reproductive and respiratory syndrome virus in swine sera. J. Vet. Diagn. Invest. 1994, 6:289-292.
39. Zimmerman J.J., Benfield D.A., Murtaugh M.P., Osorio F., Stevenson G.W., Torremorell M. Porcine reproductive and respiratory syndrome virus (porcine arterivirus). Diseases of Swine. 9th ed. 2006, 387-417. Blackwell Publishing, Ames. B.E. Straw, J.J. Zimmerman, S. D'Allaire, D.J. Taylor (Eds.).
40. Zuckermann F.A., Garcia E.A., Luque I.D., Christopher-Hennings J., Doster A., Brito M., Osorio F. Assessment of the efficacy of commercial porcine reproductive and respiratory syndrome virus (PRRSV) vaccines based on measurement of serologic response, frequency of gamma-IFN-producing cells and virological parameters of protection upon challenge. Vet. Microbiol. 2007, 123:69-85.