GGA1 overexpression attenuates amyloidogenic processing of the amyloid precursor protein in Niemann-Pick type C cells

Biochemical and Biophysical Research Communications

Volumn 450, Issue 1, 2014, Pages 160-165

  Kosicek, Marko ^a   Wunderlich, Patrick ^b   Walter, Jochen ^b   Hecimovic, Silva ^a  

^a RUDER BO KOVI INSTITUTE   (Croatia)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

Alzheimer's disease; APP; BACE1; GGA1; Niemann Pick type C; NPC1

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; BETA SECRETASE 1; BINDING PROTEIN; PROTEIN GGA1; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CELL COMPARTMENTALIZATION; CELL SURFACE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOSOME; ENZYME PHOSPHORYLATION; NIEMANN PICK DISEASE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; TRANS GOLGI NETWORK; UPREGULATION;

ALZHEIMER'S DISEASE; APP; BACE1; GGA1; NIEMANN-PICK TYPE C; NPC1;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CARRIER PROTEINS; CHO CELLS; CRICETULUS; HUMANS; MEMBRANE GLYCOPROTEINS; NIEMANN-PICK DISEASE, TYPE C; PEPTIDE FRAGMENTS; SUBCELLULAR FRACTIONS; UP-REGULATION;

EID: 84904739656     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.05.083     Document Type: Article

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