메뉴 건너뛰기




Volumn 33, Issue 8, 2014, Pages 800-813

Cardioprotective effects of curcumin and nebivolol against doxorubicin-induced cardiac toxicity in rats

Author keywords

Cardiac toxicity; curcumin; DOX; nebivolol; nitric oxide; oxidative stress

Indexed keywords

CREATINE KINASE; CREATINE KINASE MB; CURCUMIN; DOXORUBICIN; GLUTATHIONE PEROXIDASE; ISOPRENALINE; MITOCHONDRIAL DNA; NEBIVOLOL; SUPEROXIDE DISMUTASE; TROPONIN I; ANTIOXIDANT; MALONALDEHYDE; BENZOPYRAN DERIVATIVE; BIOLOGICAL MARKER; CARDIOTONIC AGENT; ETHANOLAMINE DERIVATIVE;

EID: 84904728714     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327114527628     Document Type: Article
Times cited : (59)

References (55)
  • 2
    • 0035985273 scopus 로고    scopus 로고
    • Functional monitoring of anthracycline cardiotoxicity: A prospective blinded long term observational study of outcome in 120 patients
    • Jensen BV, Skovsgaard T, Nielsen SI. Functional monitoring of anthracycline cardiotoxicity: a prospective blinded long term observational study of outcome in 120 patients. Ann Oncol. 2002 ; 13: 699-709
    • (2002) Ann Oncol , vol.13 , pp. 699-709
    • Jensen, B.V.1    Skovsgaard, T.2    Nielsen, S.I.3
  • 3
    • 14644446143 scopus 로고    scopus 로고
    • Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extract
    • 87-524 97
    • Bagchi D, Sen CK, Ray SD, et al. Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extract. Mutat Res. 2003 ;: 523 87-524 97
    • (2003) Mutat Res , pp. 523
    • Bagchi, D.1    Sen, C.K.2    Ray, S.D.3
  • 4
    • 84856386882 scopus 로고    scopus 로고
    • Cardioprotective effect of curcumin against doxorubicin-induced myocardial toxicity in albino rats
    • Swamy AV, Gulliaya S, Thippeswamy A, et al. Cardioprotective effect of curcumin against doxorubicin-induced myocardial toxicity in albino rats. Indian J Pharmacol. 2012 ; 44: 73-77
    • (2012) Indian J Pharmacol , vol.44 , pp. 73-77
    • Swamy, A.V.1    Gulliaya, S.2    Thippeswamy, A.3
  • 5
    • 22544471568 scopus 로고    scopus 로고
    • The cardiotoxicology of anthracycline chemotherapeutics: Translating molecular mechanism into preventative medicine
    • Peng X, Chen B, Lim CC, et al. The cardiotoxicology of anthracycline chemotherapeutics: translating molecular mechanism into preventative medicine. Mol Interv. 2005 ; 5: 163-171
    • (2005) Mol Interv , vol.5 , pp. 163-171
    • Peng, X.1    Chen, B.2    Lim, C.C.3
  • 6
    • 61449133232 scopus 로고    scopus 로고
    • Currying the heart: Curcumin and cardioprotection
    • Srivastav G, Mehta JL. Currying the heart: curcumin and cardioprotection. J Cardiovasc Pharmacol. 2009 ; 14: 22-27
    • (2009) J Cardiovasc Pharmacol , vol.14 , pp. 22-27
    • Srivastav, G.1    Mehta, J.L.2
  • 7
    • 67649565602 scopus 로고    scopus 로고
    • The role of Curcuma longa against doxorubicin (adriamycin)-induced toxicity in rats
    • Mohamad RH, El-Bastawesy AM, Zekry ZK, et al. The role of Curcuma longa against doxorubicin (adriamycin)-induced toxicity in rats. J Med Food. 2009 ; 12: 394-402
    • (2009) J Med Food , vol.12 , pp. 394-402
    • Mohamad, R.H.1    El-Bastawesy, A.M.2    Zekry, Z.K.3
  • 8
    • 80054790399 scopus 로고    scopus 로고
    • Amelioration of doxorubicin-induced cardiotoxicity by an anticancer-antioxidant dual-function compound, HO-3867
    • Dayton A, Selvendiran K, Meduru S, Khan M, et al. Amelioration of doxorubicin-induced cardiotoxicity by an anticancer-antioxidant dual-function compound, HO-3867. J Pharmacol Exp Ther. 2011 ; 339: 350-357
    • (2011) J Pharmacol Exp Ther , vol.339 , pp. 350-357
    • Dayton, A.1    Selvendiran, K.2    Meduru, S.3    Khan, M.4
  • 9
    • 34548824830 scopus 로고    scopus 로고
    • Nebivolol induces nitric oxide release in the heart through inducible nitric oxide synthase activation
    • Maffei A, Di Pardo A, Carangi R, et al. Nebivolol induces nitric oxide release in the heart through inducible nitric oxide synthase activation. Am J Hyperten. 2007 ; 50: 652-656
    • (2007) Am J Hyperten , vol.50 , pp. 652-656
    • Maffei, A.1    Di Pardo, A.2    Carangi, R.3
  • 10
    • 38949200975 scopus 로고    scopus 로고
    • Prominent cardioprotective effects of third generation beta blocker nebivolol against anthracycline-induced cardiotoxicity using the model of isolated perfused rat heart
    • de Nigris F, Rienzo M, Schiano C, et al. Prominent cardioprotective effects of third generation beta blocker nebivolol against anthracycline-induced cardiotoxicity using the model of isolated perfused rat heart. Eur J Canc. 2008 ; 44: 334-340
    • (2008) Eur J Canc , vol.44 , pp. 334-340
    • De Nigris, F.1    Rienzo, M.2    Schiano, C.3
  • 11
    • 33845206791 scopus 로고    scopus 로고
    • Protective effects of carvedilol against anthracycline-induced cardiomyopathy
    • Kalay N, Basar E, Ozdogru I, et al. Protective effects of carvedilol against anthracycline-induced cardiomyopathy. J Am Coll Cardiol. 2006 ; 48: 2258-2262
    • (2006) J Am Coll Cardiol , vol.48 , pp. 2258-2262
    • Kalay, N.1    Basar, E.2    Ozdogru, I.3
  • 12
    • 57749199938 scopus 로고    scopus 로고
    • Recent advances in protection against doxorubicin-induced toxicity
    • Injac R, Strukelj B. Recent advances in protection against doxorubicin-induced toxicity. Technol Canc Res Treat. 2008 ; 7: 497-516
    • (2008) Technol Canc Res Treat , vol.7 , pp. 497-516
    • Injac, R.1    Strukelj, B.2
  • 13
    • 0031801988 scopus 로고    scopus 로고
    • Curcumin attenuation of acute Adriamycin myocardial toxicity in rats
    • Venkatesan N. Curcumin attenuation of acute Adriamycin myocardial toxicity in rats. Br J Pharm. 1998 ; 12: 425-427
    • (1998) Br J Pharm , vol.12 , pp. 425-427
    • Venkatesan, N.1
  • 14
    • 42449136651 scopus 로고    scopus 로고
    • Preventive effect of nebivolol on contrast-induced nephropathy in rats
    • Toprak O, Cirit M, Tanrisev M, et al. Preventive effect of nebivolol on contrast-induced nephropathy in rats. Nephrol Dial Transplant. 2008 ; 23: 853-859
    • (2008) Nephrol Dial Transplant , vol.23 , pp. 853-859
    • Toprak, O.1    Cirit, M.2    Tanrisev, M.3
  • 15
    • 85047679058 scopus 로고
    • The Lambeth conventions: Guidelines for the study of arrhythmias in ischaemia infarction and reperfusion
    • Walker MJ, Curtis MJ, Hearse DJ, et al. The Lambeth conventions: guidelines for the study of arrhythmias in ischaemia infarction and reperfusion. Cardiovasc Res. 1988 ; 22: 447-455
    • (1988) Cardiovasc Res , vol.22 , pp. 447-455
    • Walker, M.J.1    Curtis, M.J.2    Hearse, D.J.3
  • 16
    • 36049003043 scopus 로고    scopus 로고
    • Experimental models for the study of pulmonary fibrosis: Current usefulness and future promise
    • Molina-Molina M, Pereda J, Xaubet A. Experimental models for the study of pulmonary fibrosis: current usefulness and future promise. Arch Bronconeumol. 2007 ; 43: 501-507
    • (2007) Arch Bronconeumol , vol.43 , pp. 501-507
    • Molina-Molina, M.1    Pereda, J.2    Xaubet, A.3
  • 17
    • 33846876720 scopus 로고    scopus 로고
    • Isolated heart perfusion according to Langendorff - -still viable in the new millennium
    • Skrzypiec-Spring M, Grotthus B, Szelag A, et al. Isolated heart perfusion according to Langendorff - -still viable in the new millennium. J Pharmacol Toxicol Method. 2007 ; 55: 113-126
    • (2007) J Pharmacol Toxicol Method , vol.55 , pp. 113-126
    • Skrzypiec-Spring, M.1    Grotthus, B.2    Szelag, A.3
  • 18
    • 0037092333 scopus 로고    scopus 로고
    • Role of cyclic GMP-dependent protein kinase in the contractile response to exogenous nitric oxide in rat cardiac myocytes
    • Layland J, Mei Li J, Shah AM. Role of cyclic GMP-dependent protein kinase in the contractile response to exogenous nitric oxide in rat cardiac myocytes. J Physiol. 2002 ; 540: 457-467
    • (2002) J Physiol , vol.540 , pp. 457-467
    • Layland, J.1    Mei Li, J.2    Shah, A.M.3
  • 19
    • 84884308999 scopus 로고
    • Quantitative determination of creatine phosphokinase (CPK) in Plasma
    • Rosalki SB. Quantitative determination of creatine phosphokinase (CPK) in Plasma. J Lab Clin Chem. 1977 ; 23: 646-650
    • (1977) J Lab Clin Chem , vol.23 , pp. 646-650
    • Rosalki, S.B.1
  • 20
    • 0017307083 scopus 로고
    • Determination of creatine kinase-MB in serum using inhibiting antibodies
    • Würzburg U, Hennrich N, Lang H. Determination of creatine kinase-MB in serum using inhibiting antibodies. Klin Wochenschr. 1976 ; 54: 357-360
    • (1976) Klin Wochenschr , vol.54 , pp. 357-360
    • Würzburg, U.1    Hennrich, N.2    Lang, H.3
  • 21
    • 0031948697 scopus 로고    scopus 로고
    • Comparative effects of chromium vanadium and Gymnema sylvestre on sugar-induced blood pressure elevations in SHR
    • Preuss H, Jarrel S, Scheckenobach R, et al. Comparative effects of chromium vanadium and Gymnema sylvestre on sugar-induced blood pressure elevations in SHR. J Am Coll Nutr. 1998 ; 17: 116-123
    • (1998) J Am Coll Nutr , vol.17 , pp. 116-123
    • Preuss, H.1    Jarrel, S.2    Scheckenobach, R.3
  • 22
    • 0014108436 scopus 로고
    • Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase
    • Paglia DE, Valentin N. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med. 1967 ; 70: 158-169
    • (1967) J Lab Clin Med , vol.70 , pp. 158-169
    • De, P.1    Valentin, N.2
  • 24
    • 0020448709 scopus 로고
    • Analysis of nitrite, nitrate and [15 N] nitrite in biological fluids
    • Green LC, Wagner DA, Gloowski J, et al. Analysis of nitrite, nitrate and [15 N] nitrite in biological fluids. Anal Biochem. 1982 ; 126: 131-138
    • (1982) Anal Biochem , vol.126 , pp. 131-138
    • Green, L.C.1    Wagner, D.A.2    Gloowski, J.3
  • 25
    • 0016512432 scopus 로고
    • Mitochondria and nuclei of pig and human epidermis: Isolation and lipid composition
    • Gray GM, Yardley HJ. Mitochondria and nuclei of pig and human epidermis: isolation and lipid composition. J Invest Dermatol. 1975 ; 64: 423-430
    • (1975) J Invest Dermatol , vol.64 , pp. 423-430
    • Gray, G.M.1    Yardley, H.J.2
  • 26
    • 0036715482 scopus 로고    scopus 로고
    • Carnitine inhibits cisplatin-induced injury of the kidney and small intestine
    • Chang BJ, Nishikawa M, Sato E, et al. Carnitine inhibits cisplatin-induced injury of the kidney and small intestine. Arch Biochem Biophys. 2002 ; 405: 55-64
    • (2002) Arch Biochem Biophys , vol.405 , pp. 55-64
    • Chang, B.J.1    Nishikawa, M.2    Sato, E.3
  • 27
    • 0003903343 scopus 로고    scopus 로고
    • 3rd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 2001. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press;
    • Sambrook J, Maniatis T, Fritsch FF Molecular cloning: a laboratory manual. 3 rd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 2001. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press ; 2001 :
    • (2001) Molecular Cloning: A Laboratory Manual
    • Sambrook, J.1    Maniatis, T.2    Fritsch, F.F.3
  • 28
    • 0032563825 scopus 로고    scopus 로고
    • Doxorubicin-induced cardiomyopathy
    • Singal PK, Iliskovic N. Doxorubicin-induced cardiomyopathy. N Engl J Med. 1998 ; 339: 900-905
    • (1998) N Engl J Med , vol.339 , pp. 900-905
    • Singal, P.K.1    Iliskovic, N.2
  • 30
    • 36048978125 scopus 로고    scopus 로고
    • Doxorubicin cardiotoxicity in the rat: An in vivo characterization
    • Hayward R, Hydock DS. Doxorubicin cardiotoxicity in the rat: an in vivo characterization. J Am Assoc Lab Anim Sci. 2007 ; 46: 20-32
    • (2007) J Am Assoc Lab Anim Sci , vol.46 , pp. 20-32
    • Hayward, R.1    Hydock, D.S.2
  • 31
    • 60349096342 scopus 로고    scopus 로고
    • Procyanidins produce significant attenuation of doxorubicin-induced cardiotoxicity via suppression of oxidative stress
    • Li W, Xu B, Xu J, et al. Procyanidins produce significant attenuation of doxorubicin-induced cardiotoxicity via suppression of oxidative stress. Basic Clin Pharmacol Toxicol. 2009 ; 104: 192-197
    • (2009) Basic Clin Pharmacol Toxicol , vol.104 , pp. 192-197
    • Li, W.1    Xu, B.2    Xu, J.3
  • 32
    • 67650917880 scopus 로고    scopus 로고
    • An in-depth analysis of vasodilation in the management of hypertension: Focus on adrenergic blockade
    • Bakris G. An in-depth analysis of vasodilation in the management of hypertension: focus on adrenergic blockade. J Cardiovasc Pharmacol. 2009 ; 53: 379-387
    • (2009) J Cardiovasc Pharmacol , vol.53 , pp. 379-387
    • Bakris, G.1
  • 33
    • 10744222147 scopus 로고    scopus 로고
    • Prognostic significance of an elevated creatine kinase in the absence of an elevated troponin i during an acute coronary syndrome
    • Yee KC, Mukherjee D, Smith DE, et al. Prognostic significance of an elevated creatine kinase in the absence of an elevated troponin I during an acute coronary syndrome. Am J Cardiol. 2003 ; 92: 1442-1444
    • (2003) Am J Cardiol , vol.92 , pp. 1442-1444
    • Yee, K.C.1    Mukherjee, D.2    De, S.3
  • 34
    • 0347510814 scopus 로고    scopus 로고
    • Cardiac troponin levels in heart failure
    • Potluri S, Ventura HO, Mulumudi M, et al. Cardiac troponin levels in heart failure. Cardiol Rev. 2004 ; 12: 21-25
    • (2004) Cardiol Rev , vol.12 , pp. 21-25
    • Potluri, S.1    Ventura, H.O.2    Mulumudi, M.3
  • 35
    • 37749007703 scopus 로고    scopus 로고
    • The protective effect of a purified extract of Withania somnifera against doxorubicin-induced cardiac toxicity in rats
    • Hamza A, Amin A, Daoud S. The protective effect of a purified extract of Withania somnifera against doxorubicin-induced cardiac toxicity in rats. Cell Biol Toxicol. 2008 ; 24: 63-73
    • (2008) Cell Biol Toxicol , vol.24 , pp. 63-73
    • Hamza, A.1    Amin, A.2    Daoud, S.3
  • 36
    • 52249094413 scopus 로고    scopus 로고
    • The effects of melatonin on glutathione peroxidase activity in serum and erythrocytes after adriamycin in normal and pinealectomised rats
    • Dbrowska K, Stuss M, Gromadzin-ska J, et al. The effects of melatonin on glutathione peroxidase activity in serum and erythrocytes after adriamycin in normal and pinealectomised rats. Endokrinol Pol. 2008 ; 59: 200-206
    • (2008) Endokrinol Pol , vol.59 , pp. 200-206
    • Dbrowska, K.1    Stuss, M.2    Gromadzin-Ska, J.3
  • 37
    • 0035831158 scopus 로고    scopus 로고
    • Doxorubicin and mechanical performance of cardiac trabeculae after acute and chronic treatment: A review
    • De Beer EL, Bottone AE, Voest EE. Doxorubicin and mechanical performance of cardiac trabeculae after acute and chronic treatment: a review. Eur J Pharmacol. 2001 ; 415: 1-11
    • (2001) Eur J Pharmacol , vol.415 , pp. 1-11
    • De Beer, E.L.1    Bottone, A.E.2    Voest, E.E.3
  • 38
    • 41349117220 scopus 로고    scopus 로고
    • Schisandra fructus extract ameliorates doxorubicin-induce cytotoxicity in cardiomyocytes: Altered gene expression for detoxification enzymes
    • Choi EH, Lee N, Kim HJ, et al. Schisandra fructus extract ameliorates doxorubicin-induce cytotoxicity in cardiomyocytes: altered gene expression for detoxification enzymes. Genes Nutr. 2008 ; 2: 337-345
    • (2008) Genes Nutr , vol.2 , pp. 337-345
    • Choi, E.H.1    Lee, N.2    Kim, H.J.3
  • 39
    • 34548487798 scopus 로고    scopus 로고
    • Effect of resveratrol on heart function of rats with adriamycin Failure
    • Wang GY, Wang YM, Zhang LN, et al. Effect of resveratrol on heart function of rats with adriamycin Failure. Zhongguo Zhong Yao Za Zhi. 2007 ; 32: 1563-1565
    • (2007) Zhongguo Zhong Yao Za Zhi , vol.32 , pp. 1563-1565
    • Wang, G.Y.1    Wang, Y.M.2    Zhang, L.N.3
  • 40
    • 78249258130 scopus 로고    scopus 로고
    • Short-term exercise training protects against doxorubicin-induced cardiac mitochondrial damage independent of HSP72
    • Kavazis AN, Smuder AJ, Min K, et al. Short-term exercise training protects against doxorubicin-induced cardiac mitochondrial damage independent of HSP72. Am J Physiol Heart Circ Physiol. 2010 ; 299: H1515 - H1524
    • (2010) Am J Physiol Heart Circ Physiol , vol.299
    • Kavazis, A.N.1    Smuder, A.J.2    Min, K.3
  • 41
    • 84862301097 scopus 로고    scopus 로고
    • Metformin rescues the myocardium from doxorubicin-induced energy starvation and mitochondrial damage in rats
    • Ashour AE, Sayed-Ahmed MM, Abd-Allah AR, et al. Metformin rescues the myocardium from doxorubicin-induced energy starvation and mitochondrial damage in rats. Oxid Med Cell Longe. 2012 ; 22012: 434195
    • (2012) Oxid Med Cell Longe , vol.2201 , pp. 434195
    • Ashour, A.E.1    Sayed-Ahmed, M.M.2    Abd-Allah, A.R.3
  • 42
    • 84869209094 scopus 로고    scopus 로고
    • Identification of the molecular basis of doxorubicin-induced cardiotoxicity
    • Zhang S, Liu X, Bawa-Khalfe T, et al. Identification of the molecular basis of doxorubicin-induced cardiotoxicity. Nat Med. 2012 ; 18: 1639-1642
    • (2012) Nat Med , vol.18 , pp. 1639-1642
    • Zhang, S.1    Liu, X.2    Bawa-Khalfe, T.3
  • 43
    • 33845647342 scopus 로고    scopus 로고
    • Adriamycin-induced oxidative mitochondrial cardiotoxicity
    • Berthiaume JM, WallaceK B. Adriamycin-induced oxidative mitochondrial cardiotoxicity. Cell Biol Toxicol. 2007 ; 23: 15-25
    • (2007) Cell Biol Toxicol , vol.23 , pp. 15-25
    • Berthiaume, J.M.1    Wallacek, B.2
  • 44
    • 33747814448 scopus 로고    scopus 로고
    • Alterations in myocardial energy metabolism induced by the anti-cancer drug doxorubicin
    • Tokarska-Schlattner M, Wallimann T, Schlattner U. Alterations in myocardial energy metabolism induced by the anti-cancer drug doxorubicin. C R Biol. 2006 ; 329: 657-668
    • (2006) C R Biol , vol.329 , pp. 657-668
    • Tokarska-Schlattner, M.1    Wallimann, T.2    Schlattner, U.3
  • 45
    • 3242765456 scopus 로고    scopus 로고
    • Matrix metalloproteinase activation is an early event in doxorubicin-induced cardiotoxicity
    • Bai P, Mabley JG, Liaudet L, et al. Matrix metalloproteinase activation is an early event in doxorubicin-induced cardiotoxicity. Oncol Rep. 2004 ; 11: 505-508
    • (2004) Oncol Rep , vol.11 , pp. 505-508
    • Bai, P.1    Mabley, J.G.2    Liaudet, L.3
  • 46
    • 33644909859 scopus 로고    scopus 로고
    • Effect of Curcuma longa and Ocimum sanctum on myocardial apoptosis in experimentally induced myocardial ischemic-reperfusion injury
    • Mohanty I, Arya DS, Gupta SK. Effect of Curcuma longa and Ocimum sanctum on myocardial apoptosis in experimentally induced myocardial ischemic-reperfusion injury. BMC Complement Altern Med. 2006 ; 6: 3
    • (2006) BMC Complement Altern Med , vol.6 , pp. 3
    • Mohanty, I.1    Arya, D.S.2    Gupta, S.K.3
  • 47
    • 79151481323 scopus 로고    scopus 로고
    • Curcumin promotes degradation of inducible nitric oxide synthase and suppresses its enzyme activity in RAW 264.7 cells
    • Ben P, Liu J, Lu C, et al. Curcumin promotes degradation of inducible nitric oxide synthase and suppresses its enzyme activity in RAW 264.7 cells. Int Immunopharmacol. 2011 ; 11: 179-186
    • (2011) Int Immunopharmacol , vol.11 , pp. 179-186
    • Ben, P.1    Liu, J.2    Lu, C.3
  • 48
    • 79951965233 scopus 로고    scopus 로고
    • Arsenic: Toxicity, oxidative stress and human disease
    • Jomova K, Jenisova Z, Feszterova M, et al. Arsenic: toxicity, oxidative stress and human disease. J Appl Toxicol. 2011 ; 1: 95-107
    • (2011) J Appl Toxicol , vol.1 , pp. 95-107
    • Jomova, K.1    Jenisova, Z.2    Feszterova, M.3
  • 49
    • 79551551136 scopus 로고    scopus 로고
    • Curcumin prevents DNA damage and enhances the repair potential in a chronically arsenic exposed human population in West Bengal, India
    • Roy M, Sinha D, Mukherjee S, et al. Curcumin prevents DNA damage and enhances the repair potential in a chronically arsenic exposed human population in West Bengal, India. Eur J Canc Prev. 2011 ; 20: 123-131
    • (2011) Eur J Canc Prev , vol.20 , pp. 123-131
    • Roy, M.1    Sinha, D.2    Mukherjee, S.3
  • 50
    • 44749093175 scopus 로고    scopus 로고
    • Curcumin: From ancient medicine to current clinical trials
    • Hatcher H, Planalp R, Cho J, et al. Curcumin: from ancient medicine to current clinical trials. Cell Mol Life Sci. 2008 ; 65: 1631-1652
    • (2008) Cell Mol Life Sci , vol.65 , pp. 1631-1652
    • Hatcher, H.1    Planalp, R.2    Cho, J.3
  • 51
    • 0034864469 scopus 로고    scopus 로고
    • Nebivolol, bucindolol, metoprolol and carvedilol are devoid of intrinsic sympathomimetic activity in human myocardium
    • Brixius K, Bundkirchen A, Bölck B, et al. Nebivolol, bucindolol, metoprolol and carvedilol are devoid of intrinsic sympathomimetic activity in human myocardium. Br J Pharmacol. 2001 ; 133: 1330-1338
    • (2001) Br J Pharmacol , vol.133 , pp. 1330-1338
    • Brixius, K.1    Bundkirchen, A.2    Bölck, B.3
  • 52
    • 70350445237 scopus 로고    scopus 로고
    • Nebivolol: The somewhat-different beta-adrenergic receptor blocker
    • Münzel T, Gori T. Nebivolol: the somewhat-different beta-adrenergic receptor blocker. J Am Coll Cardiol. 2009 ; 54: 1491-1499
    • (2009) J Am Coll Cardiol , vol.54 , pp. 1491-1499
    • Münzel, T.1    Gori, T.2
  • 53
    • 34547673497 scopus 로고    scopus 로고
    • Peroxynitrite: Biochemistry, pathophysiology and development of therapeutics
    • Szabó C, Ischiropoulos H, Radi R. Peroxynitrite: biochemistry, pathophysiology and development of therapeutics. Nat Rev Drug Discov. 2007 ; 6: 662-680
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 662-680
    • Szabó, C.1    Ischiropoulos, H.2    Radi, R.3
  • 54
    • 31544458671 scopus 로고    scopus 로고
    • Mitochondrial NO and reactive nitrogen species production: Does mtNOS exist?
    • Lacza Z, Pankotai E, Csordás A, et al. Mitochondrial NO and reactive nitrogen species production: does mtNOS exist?. Nitric Oxide. 2006 ; 14: 162-168
    • (2006) Nitric Oxide , vol.14 , pp. 162-168
    • Lacza, Z.1    Pankotai, E.2    Csordás, A.3
  • 55
    • 82555172350 scopus 로고    scopus 로고
    • The anti-oxidant and anti-apoptotic effects of nebivolol and zofenopril in a model of cerebral ischemia/reperfusion in rats
    • Uzar E, Acar A, Evliyaolu O, et al. The anti-oxidant and anti-apoptotic effects of nebivolol and zofenopril in a model of cerebral ischemia/reperfusion in rats. Prog Neuropsychopharmacol Biol Psychiat. 2012 ; 36: 22-28
    • (2012) Prog Neuropsychopharmacol Biol Psychiat , vol.36 , pp. 22-28
    • Uzar, E.1    Acar, A.2    Evliyaolu, O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.