Phlorizin prevents electrically-induced ventricular tachyarrhythmia during ischemia in Langendorff-perfused guinea-pig hearts

Biological and Pharmaceutical Bulletin

Volumn 37, Issue 7, 2014, Pages 1168-1176

  Hirose, Masamichi ^a   Shibazaki, Toshihide ^b   Nakada, Tsutomu ^b   Kashihara, Toshihide ^b   Yano, Shiharu ^b   Okamoto, Yoshie ^c   Isaji, Masayuki ^c   Matsushita, Naoko ^a   Taira, Eiichi ^a   Yamada, Mitsuhiko ^b  

^a IWATE MEDICAL UNIVERSITY   (Japan)

^b SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KISSEI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Ischemia; Optical mapping; Sodium glucose cotransporter; Ventricular arrhythmia

Indexed keywords

N 2 MERCAPTOPROPIONYLGLYCINE; PEROXYNITRITE; PHLORIZIN; SCAVENGER; UNCLASSIFIED DRUG; ANTIARRHYTHMIC AGENT; CALCIUM;

ANIMAL EXPERIMENT; ANTIARRHYTHMIC ACTIVITY; ARTICLE; CONTROLLED STUDY; EPICARDIUM; GUINEA PIG; HEART CONDUCTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE ISCHEMIA; HEART MUSCLE POTENTIAL; HEART VENTRICLE TACHYCARDIA; ISOLATED HEART; NONHUMAN; ACTION POTENTIAL; ANIMAL; BLOOD PRESSURE; COMPLICATION; DRUG EFFECTS; ELECTROCARDIOGRAPHY; ELECTRODE; ELECTROSTIMULATION; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE CONDUCTION SYSTEM; METABOLISM; PATHOPHYSIOLOGY; PERFUSION; TACHYCARDIA, VENTRICULAR; VOLTAGE SENSITIVE DYE IMAGING;

ACTION POTENTIALS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; BLOOD PRESSURE; CALCIUM; ELECTRIC STIMULATION; ELECTROCARDIOGRAPHY; ELECTRODES; GUINEA PIGS; HEART CONDUCTION SYSTEM; MYOCARDIAL ISCHEMIA; PERFUSION; PHLORHIZIN; TACHYCARDIA, VENTRICULAR; VENTRICULAR FUNCTION, LEFT; VOLTAGE-SENSITIVE DYE IMAGING;

EID: 84904704467     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b14-00046     Document Type: Article

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