Cigarette smoke-induced lung endothelial apoptosis and emphysema are associated with impairment of FAK and eIF2α

Microvascular Research

Volumn 94, Issue , 2014, Pages 80-89

  Sakhatskyy, Pavlo ^a   Gabino Miranda, Gustavo Andres ^a   Newton, Julie ^a   Lee, Chun Geun ^b   Choudhary, Gaurav ^a   Vang, Alexander ^a   Rounds, Sharon ^a   Lu, Qing ^a  

^a BROWN UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

AKR mice; Apoptosis; Autophagy; Cigarette smoke; EIF2alpha; Emphysema; Endothelial cell; Focal adhesion kinase; Lung; Unfolded protein response

Indexed keywords

CIGARETTE SMOKE; FOCAL ADHESION KINASE; GLUCOSE REGULATED PROTEIN 78; INITIATION FACTOR 2ALPHA; LC3B II PROTEIN; PROTEIN; UNCLASSIFIED DRUG; FOCAL ADHESION KINASE 1; HEAT SHOCK PROTEIN; INITIATION FACTOR 2; MOLECULAR CHAPERONE GRP78; PTK2 PROTEIN, MOUSE; SMOKE;

AKR MOUSE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOPHAGY; C57BL 6 MOUSE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; LUNG ALVEOLUS EPITHELIUM; LUNG EMPHYSEMA; LUNG ENDOTHELIUM; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; ADVERSE EFFECTS; ANIMAL; BOVINAE; C57BL MOUSE; CELL CULTURE; CHEMICALLY INDUCED; CYTOLOGY; DRUG EFFECTS; EMPHYSEMA; GENE EXPRESSION REGULATION; LUNG; METABOLISM; MICROCIRCULATION; PATHOLOGY; PHOSPHORYLATION; SMOKE; TIME;

ANIMALS; APOPTOSIS; AUTOPHAGY; CATTLE; CELLS, CULTURED; EMPHYSEMA; ENDOTHELIAL CELLS; EUKARYOTIC INITIATION FACTOR-2; FOCAL ADHESION KINASE 1; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; LUNG; MALE; MICE; MICE, INBRED AKR; MICE, INBRED C57BL; MICROCIRCULATION; OXIDATIVE STRESS; PHOSPHORYLATION; RATS; SMOKE; TIME FACTORS; UNFOLDED PROTEIN RESPONSE;

EID: 84904667769     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2014.05.003     Document Type: Article

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