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Volumn 155, Issue 8, 2014, Pages 1481-1491

Tear fluid hyperosmolality increases nerve impulse activity of cold thermoreceptor endings of the cornea

Author keywords

Cold thermoreceptors; Cornea; Dry eye; Hyperosmotic stress; Polymodal nociceptors; Tear osmolality

Indexed keywords

ADENOSINE TRIPHOSPHATE; BRADYKININ; HISTAMINE; PROSTAGLANDIN E2; SEROTONIN; SODIUM CHLORIDE;

EID: 84904639428     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2014.04.025     Document Type: Article
Times cited : (114)

References (66)
  • 1
    • 0035878873 scopus 로고    scopus 로고
    • Sensory experiences in humans and single unit activity in cats evoked by polymodal stimulation of the cornea
    • M.C. Acosta, C. Belmonte, and J. Gallar Sensory experiences in humans and single unit activity in cats evoked by polymodal stimulation of the cornea J Physiol 534 2001 511 525
    • (2001) J Physiol , vol.534 , pp. 511-525
    • Acosta, M.C.1    Belmonte, C.2    Gallar, J.3
  • 2
    • 66049108304 scopus 로고    scopus 로고
    • TRPC1 and TRPC6 channels cooperate with TRPV4 to mediate mechanical hyperalgesia and nociceptor sensitization
    • N. Alessandri-Haber, O.A. Dina, X. Chen, and J.D. Levine TRPC1 and TRPC6 channels cooperate with TRPV4 to mediate mechanical hyperalgesia and nociceptor sensitization J Neurosci 29 2009 6217 6228
    • (2009) J Neurosci , vol.29 , pp. 6217-6228
    • Alessandri-Haber, N.1    Dina, O.A.2    Chen, X.3    Levine, J.D.4
  • 4
    • 34248995257 scopus 로고    scopus 로고
    • The action potential in mammalian central neurons
    • B.P. Bean The action potential in mammalian central neurons Nat Rev Neurosci 8 2007 451 465
    • (2007) Nat Rev Neurosci , vol.8 , pp. 451-465
    • Bean, B.P.1
  • 7
    • 0025731043 scopus 로고
    • Excitation by irritant chemical substances of sensory afferent units in the cat's cornea
    • C. Belmonte, J. Gallar, M.A. Pozo, and I. Rebollo Excitation by irritant chemical substances of sensory afferent units in the cat's cornea J Physiol 437 1991 709 725
    • (1991) J Physiol , vol.437 , pp. 709-725
    • Belmonte, C.1    Gallar, J.2    Pozo, M.A.3    Rebollo, I.4
  • 8
    • 80051731823 scopus 로고    scopus 로고
    • Cold thermoreceptors, unexpected players in tear production and ocular dryness sensations
    • C. Belmonte, and J. Gallar Cold thermoreceptors, unexpected players in tear production and ocular dryness sensations Invest Ophthalmol Vis Sci 52 2011 3888 3892
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 3888-3892
    • Belmonte, C.1    Gallar, J.2
  • 9
    • 0019731761 scopus 로고
    • Responses of cat corneal sensory receptors to mechanical and thermal stimulation
    • C. Belmonte, and F. Giraldez Responses of cat corneal sensory receptors to mechanical and thermal stimulation J Physiol 321 1981 355 368
    • (1981) J Physiol , vol.321 , pp. 355-368
    • Belmonte, C.1    Giraldez, F.2
  • 12
    • 34548388508 scopus 로고    scopus 로고
    • TASK-3 two-pore domain potassium channels enable sustained high-frequency firing in cerebellar granule neurons
    • S.G. Brickley, M.I. Aller, C. Sandu, E.L. Veale, F.G. Alder, H. Sambi, A. Mathie, and W. Wisden TASK-3 two-pore domain potassium channels enable sustained high-frequency firing in cerebellar granule neurons J Neurosci 27 2007 9329 9340
    • (2007) J Neurosci , vol.27 , pp. 9329-9340
    • Brickley, S.G.1    Aller, M.I.2    Sandu, C.3    Veale, E.L.4    Alder, F.G.5    Sambi, H.6    Mathie, A.7    Wisden, W.8
  • 13
    • 0032191372 scopus 로고    scopus 로고
    • Tetrodotoxin-resistant impulses in single nociceptor nerve terminals in guinea-pig corneas
    • J. Brock, E.M. McLachlan, and C. Belmonte Tetrodotoxin-resistant impulses in single nociceptor nerve terminals in guinea-pig corneas J Physiol 512 1998 211 217
    • (1998) J Physiol , vol.512 , pp. 211-217
    • Brock, J.1    McLachlan, E.M.2    Belmonte, C.3
  • 14
    • 0035369258 scopus 로고    scopus 로고
    • Differences between nerve terminal impulses of polymodal nociceptors and cold sensory receptors of the guinea-pig cornea
    • J.A. Brock, S. Pianova, and C. Belmonte Differences between nerve terminal impulses of polymodal nociceptors and cold sensory receptors of the guinea-pig cornea J Physiol 533 2001 493 501
    • (2001) J Physiol , vol.533 , pp. 493-501
    • Brock, J.A.1    Pianova, S.2    Belmonte, C.3
  • 16
    • 79956357900 scopus 로고    scopus 로고
    • A solute gradient in the tear meniscus. I. A hypothesis to explain Marx's line
    • A.J. Bron, N. Yokoi, E.A. Gaffney, and J.M. Tiffany A solute gradient in the tear meniscus. I. A hypothesis to explain Marx's line Ocul Surf 9 2011 70 91
    • (2011) Ocul Surf , vol.9 , pp. 70-91
    • Bron, A.J.1    Yokoi, N.2    Gaffney, E.A.3    Tiffany, J.M.4
  • 17
    • 62749130877 scopus 로고    scopus 로고
    • Action potential initiation in the peripheral terminals of cold-sensitive neurons innervating the guinea pig cornea
    • R.W. Carr, S. Pianova, D.D. McKemy, and J.A. Brock Action potential initiation in the peripheral terminals of cold-sensitive neurons innervating the guinea pig cornea J Physiol 587 2009 1249 1264
    • (2009) J Physiol , vol.587 , pp. 1249-1264
    • Carr, R.W.1    Pianova, S.2    McKemy, D.D.3    Brock, J.A.4
  • 18
    • 0031055619 scopus 로고    scopus 로고
    • Importance of the lipid layer in human tear film stability and evaporation
    • J.P. Craig, and A. Tomlinson Importance of the lipid layer in human tear film stability and evaporation Optom Vis Sci 74 1997 8 13
    • (1997) Optom Vis Sci , vol.74 , pp. 8-13
    • Craig, J.P.1    Tomlinson, A.2
  • 19
    • 84880326046 scopus 로고    scopus 로고
    • Formation and function of the tear film
    • P.L. Kaufman, A. Alm, 11th ed. Saunders Elsevier
    • D.A. Dartt Formation and function of the tear film P.L. Kaufman, A. Alm, Adler's physiology of the eye 11th ed. 2011 Saunders Elsevier 350 362
    • (2011) Adler's Physiology of the Eye , pp. 350-362
    • Dartt, D.A.1
  • 21
    • 84885971769 scopus 로고    scopus 로고
    • Neuropathic pain: Pathophysiological response of nerves to injury
    • S. McMahon, M. Koltzenburg, I. Tracey, D.C. Turk, 6th ed. Elsevier Philadelphia, PA
    • M. Devor Neuropathic pain: Pathophysiological response of nerves to injury S. McMahon, M. Koltzenburg, I. Tracey, D.C. Turk, Wall & Melzack's textbook of pain 6th ed. 2014 Elsevier Philadelphia, PA 861 888
    • (2014) Wall & Melzack's Textbook of Pain , pp. 861-888
    • Devor, M.1
  • 23
    • 34250196492 scopus 로고    scopus 로고
    • The correlation between the tear film lipid layer and dry eye disease
    • G.N. Foulks The correlation between the tear film lipid layer and dry eye disease Surv Ophthalmol 52 2007 369 374
    • (2007) Surv Ophthalmol , vol.52 , pp. 369-374
    • Foulks, G.N.1
  • 24
    • 84865168583 scopus 로고    scopus 로고
    • Fluids of the ocular surface: Concepts, functions and physics
    • I.C. Franzco Fluids of the ocular surface: Concepts, functions and physics Clin Exp Ophthalmol 40 2012 634 643
    • (2012) Clin Exp Ophthalmol , vol.40 , pp. 634-643
    • Franzco, I.C.1
  • 25
    • 74749105572 scopus 로고    scopus 로고
    • A mass and solute balance model for tear volume and osmolality in the normal and the dry eye
    • E.A. Gaffney, J.M. Tiffany, N. Yokoi, and A.J. Bron A mass and solute balance model for tear volume and osmolality in the normal and the dry eye Prog Retin Eye Res 29 2010 59 78
    • (2010) Prog Retin Eye Res , vol.29 , pp. 59-78
    • Gaffney, E.A.1    Tiffany, J.M.2    Yokoi, N.3    Bron, A.J.4
  • 26
    • 0027291678 scopus 로고
    • Response of sensory units with unmyelinated fibres to mechanical, thermal and chemical stimulation of the cat's cornea
    • J. Gallar, M.A. Pozo, R.P. Tuckett, and C. Belmonte Response of sensory units with unmyelinated fibres to mechanical, thermal and chemical stimulation of the cat's cornea J Physiol 468 1993 609 622
    • (1993) J Physiol , vol.468 , pp. 609-622
    • Gallar, J.1    Pozo, M.A.2    Tuckett, R.P.3    Belmonte, C.4
  • 27
    • 0028098188 scopus 로고
    • Human tear film electrolyte concentrations in health and dry-eye disease
    • J.P. Gilbard Human tear film electrolyte concentrations in health and dry-eye disease Int Ophthalmol Clin 34 1994 27 36
    • (1994) Int Ophthalmol Clin , vol.34 , pp. 27-36
    • Gilbard, J.P.1
  • 29
    • 0018389950 scopus 로고
    • Tear osmolality and ocular surface disease in keratoconjunctivitis sicca
    • J.P. Gilbard, and R.L. Farris Tear osmolality and ocular surface disease in keratoconjunctivitis sicca Arch Ophthalmol. 97 1979 1642 1646
    • (1979) Arch Ophthalmol. , vol.97 , pp. 1642-1646
    • Gilbard, J.P.1    Farris, R.L.2
  • 30
    • 0023007356 scopus 로고
    • A proposed mechanism for increased tear-film osmolarity in contact lens wearers
    • J.P. Gilbard, K.L. Gray, and S.R. Rossi A proposed mechanism for increased tear-film osmolarity in contact lens wearers Am J Ophthalmol 102 1986 505 507
    • (1986) Am J Ophthalmol , vol.102 , pp. 505-507
    • Gilbard, J.P.1    Gray, K.L.2    Rossi, S.R.3
  • 31
    • 57049153922 scopus 로고    scopus 로고
    • Hypoosmotic- and pressure-induced membrane stretch activate TRPC5 channels
    • A. Gomis, S. Soriano, C. Belmonte, and F. Viana Hypoosmotic- and pressure-induced membrane stretch activate TRPC5 channels J Physiol 586 2008 5633 5649
    • (2008) J Physiol , vol.586 , pp. 5633-5649
    • Gomis, A.1    Soriano, S.2    Belmonte, C.3    Viana, F.4
  • 32
    • 67649865276 scopus 로고    scopus 로고
    • Deletion of TASK1 and TASK3 channels disrupts intrinsic excitability but does not abolish glucose or pH responses of orexin/hypocretin neurons
    • J.A. Gonzalez, L.T. Jensen, S.E. Doyle, M. Miranda-Anaya, M. Menaker, L. Fugger, D.A. Bayliss, and D. Burdakow Deletion of TASK1 and TASK3 channels disrupts intrinsic excitability but does not abolish glucose or pH responses of orexin/hypocretin neurons Eur J Neurosci 30 2009 57 64
    • (2009) Eur J Neurosci , vol.30 , pp. 57-64
    • Gonzalez, J.A.1    Jensen, L.T.2    Doyle, S.E.3    Miranda-Anaya, M.4    Menaker, M.5    Fugger, L.6    Bayliss, D.A.7    Burdakow, D.8
  • 33
    • 0026026676 scopus 로고
    • Surface charges and ion channel function
    • W.N. Green, and O.S. Andersen Surface charges and ion channel function Annu Rev Physiol 53 1991 341 359
    • (1991) Annu Rev Physiol , vol.53 , pp. 341-359
    • Green, W.N.1    Andersen, O.S.2
  • 34
    • 0038498142 scopus 로고    scopus 로고
    • Molecular and functional characterization of the melastatin-related cation channel TRPM3
    • C. Grimm, R. Kraft, S. Sauerbruch, G. Schultz, and C. Harteneck Molecular and functional characterization of the melastatin-related cation channel TRPM3 J Biol Chem 278 2003 21493 21501
    • (2003) J Biol Chem , vol.278 , pp. 21493-21501
    • Grimm, C.1    Kraft, R.2    Sauerbruch, S.3    Schultz, G.4    Harteneck, C.5
  • 35
    • 0003004656 scopus 로고
    • Pain and inflammation
    • M.R. Bond, J.B. Charlton, C.J. Woolf, Proceedings of the VIth world congress on pain Amsterdam Elsevier
    • H.O. Handwerker, and P.W. Reeh Pain and inflammation M.R. Bond, J.B. Charlton, C.J. Woolf, Pain research and clinical management Proceedings of the VIth world congress on pain vol. 4 1991 Amsterdam Elsevier 59 70
    • (1991) Pain Research and Clinical Management , vol.4 , pp. 59-70
    • Handwerker, H.O.1    Reeh, P.W.2
  • 37
    • 77955884939 scopus 로고    scopus 로고
    • Cold-sensitive corneal afferents respond to a variety of ocular stimuli central to tear production: Implications for dry eye disease
    • H. Hirata, and I.D. Meng Cold-sensitive corneal afferents respond to a variety of ocular stimuli central to tear production: implications for dry eye disease Invest Ophthalmol Vis Sci 51 2010 3969 3976
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 3969-3976
    • Hirata, H.1    Meng, I.D.2
  • 38
    • 2442629555 scopus 로고    scopus 로고
    • A novel class of neurons at the trigeminal subnucleus interpolaris/caudalis transition region monitors ocular surface fluid status and modulates tear production
    • H. Hirata, K. Okamoto, A. Tashiro, and D.A. Bereiter A novel class of neurons at the trigeminal subnucleus interpolaris/caudalis transition region monitors ocular surface fluid status and modulates tear production J Neurosci 24 2004 4224 4232
    • (2004) J Neurosci , vol.24 , pp. 4224-4232
    • Hirata, H.1    Okamoto, K.2    Tashiro, A.3    Bereiter, D.A.4
  • 39
    • 0014635477 scopus 로고
    • Evaporation rate of water from the precorneal tear film and cornea in the rabbit
    • S. Iwata, M.A. Lemp, F.J. Holly, and C.H. Dohlman Evaporation rate of water from the precorneal tear film and cornea in the rabbit Invest Ophthalmol 8 1969 613 619
    • (1969) Invest Ophthalmol , vol.8 , pp. 613-619
    • Iwata, S.1    Lemp, M.A.2    Holly, F.J.3    Dohlman, C.H.4
  • 40
    • 0344133649 scopus 로고
    • Phase plane trajectories of the muscle spike potential
    • H. Jenerick Phase plane trajectories of the muscle spike potential Biophys J 3 1963 363 377
    • (1963) Biophys J , vol.3 , pp. 363-377
    • Jenerick, H.1
  • 41
    • 0038752614 scopus 로고    scopus 로고
    • The principle of gating charge movement in a voltage-dependent K+ channel
    • Y. Jiang, V. Ruta, J. Chen, A. Lee, and R. MacKinnon The principle of gating charge movement in a voltage-dependent K+ channel Nature 423 2003 42 48
    • (2003) Nature , vol.423 , pp. 42-48
    • Jiang, Y.1    Ruta, V.2    Chen, J.3    Lee, A.4    Mackinnon, R.5
  • 42
    • 77049091145 scopus 로고    scopus 로고
    • The association between symptoms of discomfort and signs in dry eye
    • M.E. Johnson The association between symptoms of discomfort and signs in dry eye Ocul Surf 7 2009 199 211
    • (2009) Ocul Surf , vol.7 , pp. 199-211
    • Johnson, M.E.1
  • 43
    • 84862503517 scopus 로고    scopus 로고
    • Effects of tear hyperosmolality on conjunctival cells in mild to moderate dry eye
    • G. Julio, S. Lluch, P. Pujol, and M.D. Merindano Effects of tear hyperosmolality on conjunctival cells in mild to moderate dry eye Ophthalmic Physiol Opt 32 2012 317 323
    • (2012) Ophthalmic Physiol Opt , vol.32 , pp. 317-323
    • Julio, G.1    Lluch, S.2    Pujol, P.3    Merindano, M.D.4
  • 45
    • 0026440476 scopus 로고
    • Excitation of cutaneous afferent nerve endings in vitro by a combination of inflammatory mediators and conditioning effect of substance P
    • W. Kessler, C. Kirchoff, P.W. Reeh, and H.O. Handwerker Excitation of cutaneous afferent nerve endings in vitro by a combination of inflammatory mediators and conditioning effect of substance P Exp Brain Res 91 1992 467 476
    • (1992) Exp Brain Res , vol.91 , pp. 467-476
    • Kessler, W.1    Kirchoff, C.2    Reeh, P.W.3    Handwerker, H.O.4
  • 47
    • 84880150254 scopus 로고    scopus 로고
    • Dry eye modifies the thermal and menthol responses in rat corneal primary afferent cool cells
    • M. Kurose, and I.D. Meng Dry eye modifies the thermal and menthol responses in rat corneal primary afferent cool cells J Neurophysiol 110 2013 495 504
    • (2013) J Neurophysiol , vol.110 , pp. 495-504
    • Kurose, M.1    Meng, I.D.2
  • 50
    • 0022531113 scopus 로고
    • Non-invasive tear film break-up time: Sensitivity and specificity
    • L.S. Mengher, K.S. Pandher, and A.J. Bron Non-invasive tear film break-up time: Sensitivity and specificity Acta Ophthalmol 64 1986 441 444
    • (1986) Acta Ophthalmol , vol.64 , pp. 441-444
    • Mengher, L.S.1    Pandher, K.S.2    Bron, A.J.3
  • 51
    • 0019866817 scopus 로고
    • Myelinated nociceptive afferents account for the hyperalgesia that follows a burn to the hand
    • R.A. Meyer, and J.N. Campbell Myelinated nociceptive afferents account for the hyperalgesia that follows a burn to the hand Science 213 1981 1527 1529
    • (1981) Science , vol.213 , pp. 1527-1529
    • Meyer, R.A.1    Campbell, J.N.2
  • 52
    • 0002974924 scopus 로고
    • The oily layer of the tear film and evaporation from the corneal surface
    • S. Mishima, and D.M. Maurice The oily layer of the tear film and evaporation from the corneal surface Exp Eye Res 1 1961 39 45
    • (1961) Exp Eye Res , vol.1 , pp. 39-45
    • Mishima, S.1    Maurice, D.M.2
  • 55
    • 46149095945 scopus 로고    scopus 로고
    • DEWS
    • Report of the International Dry eye Workshop
    • Report of the International Dry eye Workshop DEWS Ocul Surf 5 2007 65 204
    • (2007) Ocul Surf , vol.5 , pp. 65-204
  • 56
    • 21844436650 scopus 로고    scopus 로고
    • Effect of experimental dry eye on tear sodium concentration in the mouse
    • P. Stewart, Z. Chen, W. Farley, L. Olmos, and S.C. Pflugfelder Effect of experimental dry eye on tear sodium concentration in the mouse Eye Contact Lens 31 2005 175 178
    • (2005) Eye Contact Lens , vol.31 , pp. 175-178
    • Stewart, P.1    Chen, Z.2    Farley, W.3    Olmos, L.4    Pflugfelder, S.C.5
  • 58
    • 78149463506 scopus 로고    scopus 로고
    • Evaluation of tear evaporation from ocular surface by functional infrared thermography
    • J.H. Tan, E.Y.K. Ng, and U.R. Acharya Evaluation of tear evaporation from ocular surface by functional infrared thermography Med Phys 37 2010 6022 6034
    • (2010) Med Phys , vol.37 , pp. 6022-6034
    • Tan, J.H.1    Ng, E.Y.K.2    Acharya, U.R.3
  • 59
    • 77953808416 scopus 로고    scopus 로고
    • Behavioral and neurophysiological correlates of nociception in an animal model of photokeratitis
    • A. Tashiro, K. Okamoto, Z. Chang, and D.A. Bereiter Behavioral and neurophysiological correlates of nociception in an animal model of photokeratitis Neuroscience 169 2010 455 462
    • (2010) Neuroscience , vol.169 , pp. 455-462
    • Tashiro, A.1    Okamoto, K.2    Chang, Z.3    Bereiter, D.A.4
  • 60
    • 77049109452 scopus 로고    scopus 로고
    • Inputs and outputs of the lacrimal system: Review of production and evaporative loss
    • A. Tomlinson, M.G. Doane, and A. McFadyen Inputs and outputs of the lacrimal system: Review of production and evaporative loss Ocul Surf 7 2009 186 198
    • (2009) Ocul Surf , vol.7 , pp. 186-198
    • Tomlinson, A.1    Doane, M.G.2    McFadyen, A.3
  • 61
    • 77956230790 scopus 로고    scopus 로고
    • Comparison of human tear film osmolality measured by electrical impedance and freezing point depression techniques
    • A. Tomlinson, L.C. McCann, and E.I. Pearce Comparison of human tear film osmolality measured by electrical impedance and freezing point depression techniques Cornea 29 2010 1036 1041
    • (2010) Cornea , vol.29 , pp. 1036-1041
    • Tomlinson, A.1    McCann, L.C.2    Pearce, E.I.3
  • 62
    • 80053320072 scopus 로고    scopus 로고
    • Hyperosmolar stress upregulates HLA-DR expression in human conjunctival epithelium in dry eye patients and in vitro models
    • P. Versura, V. Profazio, C. Schiavi, and E.C. Campos Hyperosmolar stress upregulates HLA-DR expression in human conjunctival epithelium in dry eye patients and in vitro models Invest Ophthalmol Vis Sci 52 2011 5488 5496
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 5488-5496
    • Versura, P.1    Profazio, V.2    Schiavi, C.3    Campos, E.C.4
  • 65
    • 39049158670 scopus 로고    scopus 로고
    • Transient receptor potential A1 mediates an osmotically activated ion channel
    • X.F. Zhang, J. Chen, C.R. Faltynek, R.B. Moreland, and T.R. Neelands Transient receptor potential A1 mediates an osmotically activated ion channel Eur J Neurosci 27 2008 605 611
    • (2008) Eur J Neurosci , vol.27 , pp. 605-611
    • Zhang, X.F.1    Chen, J.2    Faltynek, C.R.3    Moreland, R.B.4    Neelands, T.R.5
  • 66
    • 84864753117 scopus 로고    scopus 로고
    • Coupling fluid and solute dynamics within the ocular surface tear film: A modelling study of black line osmolality
    • V.S. Zubkov, C.J. Breward, and E.A. Gaffney Coupling fluid and solute dynamics within the ocular surface tear film: A modelling study of black line osmolality Bull Math Biol 74 2012 2062 2093
    • (2012) Bull Math Biol , vol.74 , pp. 2062-2093
    • Zubkov, V.S.1    Breward, C.J.2    Gaffney, E.A.3


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