메뉴 건너뛰기




Volumn 94, Issue , 2014, Pages 17-27

Characterization of nanoparticle delivery in microcirculation using a microfluidic device

Author keywords

Bifurcation region; Microcirculation; Microfluidic chip; Microvasculature; Nanoparticle; Particle distribution; Red blood cells; Shear rate

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; NANOPARTICLE; ANTIBODY; DIMETICONE; DRUG CARRIER; POLYSTYRENE DERIVATIVE;

EID: 84904617889     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2014.04.008     Document Type: Article
Times cited : (36)

References (71)
  • 1
    • 0021723554 scopus 로고
    • Red blood cell deformability influences platelets-vessel wall interaction in flowing blood
    • Aarts P., Heethaar R., Sixma J. Red blood cell deformability influences platelets-vessel wall interaction in flowing blood. Blood 1984, 64(6):1228-1233.
    • (1984) Blood , vol.64 , Issue.6 , pp. 1228-1233
    • Aarts, P.1    Heethaar, R.2    Sixma, J.3
  • 2
    • 0038000710 scopus 로고    scopus 로고
    • Rheological properties of the blood influencing selectin-mediated adhesion of flowing leukocytes
    • Abbitt K.B., Nash G.B. Rheological properties of the blood influencing selectin-mediated adhesion of flowing leukocytes. Am. J. Physiol. Heart Circ. Physiol. 2003, 285(1):H229-H240.
    • (2003) Am. J. Physiol. Heart Circ. Physiol. , vol.285 , Issue.1
    • Abbitt, K.B.1    Nash, G.B.2
  • 3
    • 84873252557 scopus 로고    scopus 로고
    • Liposomal drug delivery systems: From concept to clinical applications
    • Allen T.M., Cullis P.R. Liposomal drug delivery systems: From concept to clinical applications. Adv. Drug Deliv. Rev. 2013, 65(1):36-48.
    • (2013) Adv. Drug Deliv. Rev. , vol.65 , Issue.1 , pp. 36-48
    • Allen, T.M.1    Cullis, P.R.2
  • 4
    • 0035908941 scopus 로고    scopus 로고
    • Circulating Cell Adhesion Molecules and Death in Patients With Coronary Artery Disease
    • Blankenberg S., et al. Circulating Cell Adhesion Molecules and Death in Patients With Coronary Artery Disease. Circulation 2001, 104(12):1336-1342.
    • (2001) Circulation , vol.104 , Issue.12 , pp. 1336-1342
    • Blankenberg, S.1
  • 5
    • 70349085343 scopus 로고    scopus 로고
    • Flow dynamics, binding and detachment of spherical carriers targeted to ICAM-1 on endothelial cells
    • Calderon A.J., Muzykantov V., Muro S., Eckmann D.M. Flow dynamics, binding and detachment of spherical carriers targeted to ICAM-1 on endothelial cells. Biorheology 2009, 46:323-341.
    • (2009) Biorheology , vol.46 , pp. 323-341
    • Calderon, A.J.1    Muzykantov, V.2    Muro, S.3    Eckmann, D.M.4
  • 6
    • 72149100143 scopus 로고    scopus 로고
    • Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers
    • Charoenphol P., Huang R.B., Eniola-Adefeso O. Potential role of size and hemodynamics in the efficacy of vascular-targeted spherical drug carriers. Biomaterials 2010, 31(6):1392-1402.
    • (2010) Biomaterials , vol.31 , Issue.6 , pp. 1392-1402
    • Charoenphol, P.1    Huang, R.B.2    Eniola-Adefeso, O.3
  • 7
    • 67649946079 scopus 로고    scopus 로고
    • A novel multishear microdevice for studying cell mechanics
    • Chau L., Doran M., Cooper-White J. A novel multishear microdevice for studying cell mechanics. Lab Chip 2009, 9(13):1897-1902.
    • (2009) Lab Chip , vol.9 , Issue.13 , pp. 1897-1902
    • Chau, L.1    Doran, M.2    Cooper-White, J.3
  • 8
    • 40949127319 scopus 로고    scopus 로고
    • Therapeutic Nanoparticles for Drug Delivery in Cancer
    • Cho K., et al. Therapeutic Nanoparticles for Drug Delivery in Cancer. Clin. Cancer Res. 2008, 14(5):1310-1316.
    • (2008) Clin. Cancer Res. , vol.14 , Issue.5 , pp. 1310-1316
    • Cho, K.1
  • 9
    • 84862673737 scopus 로고    scopus 로고
    • PLGA-based nanoparticles: An overview of biomedical applications
    • Danhier F., et al. PLGA-based nanoparticles: An overview of biomedical applications. J. Control. Release 2012, 161(2):505-522.
    • (2012) J. Control. Release , vol.161 , Issue.2 , pp. 505-522
    • Danhier, F.1
  • 11
    • 0023694565 scopus 로고
    • Conditions for the occurrence of large near-wall excesses of small particles during blood flow
    • Eckstein E.C., Tilles A.W., Millero F.J. Conditions for the occurrence of large near-wall excesses of small particles during blood flow. Microvasc. Res. 1988, 36(1):31-39.
    • (1988) Microvasc. Res. , vol.36 , Issue.1 , pp. 31-39
    • Eckstein, E.C.1    Tilles, A.W.2    Millero, F.J.3
  • 12
    • 0001331302 scopus 로고
    • The Viscosity of the blood in narrow capillary tubes
    • Fåhræus R., Lindqvist T. The Viscosity of the blood in narrow capillary tubes. Am. J. Physiol. Leg. Content 1931, 96(3):562-568.
    • (1931) Am. J. Physiol. Leg. Content , vol.96 , Issue.3 , pp. 562-568
    • Fåhræus, R.1    Lindqvist, T.2
  • 13
    • 0021913931 scopus 로고
    • Analysis of the effects of measured white blood cell entrance times on hemodynamics in a computer model of a microvascular bed
    • Fenton B., Wilson D., Cokelet G. Analysis of the effects of measured white blood cell entrance times on hemodynamics in a computer model of a microvascular bed. Pflugers Arch. 1985, 403(4):396-401.
    • (1985) Pflugers Arch. , vol.403 , Issue.4 , pp. 396-401
    • Fenton, B.1    Wilson, D.2    Cokelet, G.3
  • 14
    • 0015542158 scopus 로고
    • Stochastic flow in capillary blood vessels
    • Fung Y.-C. Stochastic flow in capillary blood vessels. Microvasc. Res. 1973, 5(1):34-48.
    • (1973) Microvasc. Res. , vol.5 , Issue.1 , pp. 34-48
    • Fung, Y.-C.1
  • 15
    • 0014698994 scopus 로고
    • Velocity profiles of human blood at normal and reduced hematocrit in glass tubes up to 130μ diameter
    • Gaehtgens P., Meiselman H.J., Wayland H. Velocity profiles of human blood at normal and reduced hematocrit in glass tubes up to 130μ diameter. Microvasc. Res. 1970, 2(1):13-23.
    • (1970) Microvasc. Res. , vol.2 , Issue.1 , pp. 13-23
    • Gaehtgens, P.1    Meiselman, H.J.2    Wayland, H.3
  • 16
    • 0027486922 scopus 로고
    • Circulating adhesion molecules in disease
    • Gearing A.J.H., Newman W. Circulating adhesion molecules in disease. Immunol. Today 1993, 14(10):506-512.
    • (1993) Immunol. Today , vol.14 , Issue.10 , pp. 506-512
    • Gearing, A.J.H.1    Newman, W.2
  • 17
    • 53549112490 scopus 로고    scopus 로고
    • The margination propensity of spherical particles for vascular targeting in the microcirculation
    • Gentile F., et al. The margination propensity of spherical particles for vascular targeting in the microcirculation. J. Nanobiotechnol. 2008, 6(1):9.
    • (2008) J. Nanobiotechnol. , vol.6 , Issue.1 , pp. 9
    • Gentile, F.1
  • 18
    • 1842330850 scopus 로고    scopus 로고
    • Biomechanical activation: an emerging paradigm in endothelial adhesion biology
    • Gimbrone M.A., Nagel T., Topper J.N. Biomechanical activation: an emerging paradigm in endothelial adhesion biology. J. Clin. Invest. 1997, 99(8):1809-1813.
    • (1997) J. Clin. Invest. , vol.99 , Issue.8 , pp. 1809-1813
    • Gimbrone, M.A.1    Nagel, T.2    Topper, J.N.3
  • 19
    • 0008884532 scopus 로고
    • Slow viscous motion of a sphere parallel to a plane wall-II Couette flow
    • Goldman A.J., Cox R.G., Brenner H. Slow viscous motion of a sphere parallel to a plane wall-II Couette flow. Chem. Eng. Sci. 1967, 22(4):653-660.
    • (1967) Chem. Eng. Sci. , vol.22 , Issue.4 , pp. 653-660
    • Goldman, A.J.1    Cox, R.G.2    Brenner, H.3
  • 20
    • 0022616458 scopus 로고
    • The microcirculatory society Eugene M. Landis award lecture: The microrheology of human blood
    • Goldsmith Harry L. The microcirculatory society Eugene M. Landis award lecture: The microrheology of human blood. Microvasc. Res. 1986, 31(2):121-142.
    • (1986) Microvasc. Res. , vol.31 , Issue.2 , pp. 121-142
    • Goldsmith, H.L.1
  • 21
    • 0002178263 scopus 로고
    • Particle motions in sheared suspensions XIII. The spin and rotation of disks
    • Goldsmith H.L., Mason S.G. Particle motions in sheared suspensions XIII. The spin and rotation of disks. J. Fluid Mech. 1962, 12(01):88-96.
    • (1962) J. Fluid Mech. , vol.12 , Issue.1 , pp. 88-96
    • Goldsmith, H.L.1    Mason, S.G.2
  • 22
    • 0002209355 scopus 로고
    • The microrheology of dispersions
    • Academic Press, New York, F.R. Eirich (Ed.)
    • Goldsmith H.L., Mason S.G. The microrheology of dispersions. Rheology, Theory, and Applications 1967, 4:85-250. Academic Press, New York. F.R. Eirich (Ed.).
    • (1967) Rheology, Theory, and Applications , vol.4 , pp. 85-250
    • Goldsmith, H.L.1    Mason, S.G.2
  • 23
    • 50849096670 scopus 로고    scopus 로고
    • Quantifying Nanoparticle Adhesion Mediated by Specific Molecular Interactions
    • Haun J.B., Hammer D.A. Quantifying Nanoparticle Adhesion Mediated by Specific Molecular Interactions. Langmuir 2008, 24(16):8821-8832.
    • (2008) Langmuir , vol.24 , Issue.16 , pp. 8821-8832
    • Haun, J.B.1    Hammer, D.A.2
  • 24
    • 0036835385 scopus 로고    scopus 로고
    • Lipid-mediated gene transfection of intercellular adhesion molecule-1 suppresses the peritoneal metastasis of gastric carcinoma
    • Hiroaki Tanaka, Masakazu Yashiro, Sunami Takeshi, Ohira Masaichi, Hirakawa K., Chung Y.S. Lipid-mediated gene transfection of intercellular adhesion molecule-1 suppresses the peritoneal metastasis of gastric carcinoma. Int. J. Mol. Med. 2002, 10(5).
    • (2002) Int. J. Mol. Med. , vol.10 , Issue.5
    • Hiroaki, T.1    Masakazu, Y.2    Sunami, T.3    Ohira, M.4    Hirakawa, K.5    Chung, Y.S.6
  • 25
    • 38349100245 scopus 로고    scopus 로고
    • In-vitro study on the hemorheological characteristics of chicken blood in microcirculation
    • Ji Ho Seong, J.Y.L., S.J.L. In-vitro study on the hemorheological characteristics of chicken blood in microcirculation. Rheol. J. 2007, 19:89-95.
    • (2007) Rheol. J. , vol.19 , pp. 89-95
    • Ji, H.S.1
  • 26
    • 0037601888 scopus 로고    scopus 로고
    • Requirements for ICAM-1 immunogene therapy of lymphoma
    • Kanwar J.R., et al. Requirements for ICAM-1 immunogene therapy of lymphoma. Cancer Gene Ther. 2003, 10(6):468-476.
    • (2003) Cancer Gene Ther. , vol.10 , Issue.6 , pp. 468-476
    • Kanwar, J.R.1
  • 27
    • 68649096392 scopus 로고    scopus 로고
    • The cell-free layer in microvascular blood flow
    • Kim S., et al. The cell-free layer in microvascular blood flow. Biorheology 2009, 46(3):181-189.
    • (2009) Biorheology , vol.46 , Issue.3 , pp. 181-189
    • Kim, S.1
  • 28
    • 84856552548 scopus 로고    scopus 로고
    • Biodegradable nanoparticles mimicking platelet binding as a targeted and controlled drug delivery system
    • Kona S., et al. Biodegradable nanoparticles mimicking platelet binding as a targeted and controlled drug delivery system. Int. J. Pharm. 2012, 423(2):516-524.
    • (2012) Int. J. Pharm. , vol.423 , Issue.2 , pp. 516-524
    • Kona, S.1
  • 29
    • 84883205556 scopus 로고    scopus 로고
    • Adhesive interaction of functionalized particles and endothelium in idealized microvascular networks
    • Lamberti G., et al. Adhesive interaction of functionalized particles and endothelium in idealized microvascular networks. Microvasc. Res. 2013, 89:107-114.
    • (2013) Microvasc. Res. , vol.89 , pp. 107-114
    • Lamberti, G.1
  • 30
    • 84862698355 scopus 로고    scopus 로고
    • Drug targeting to tumors: Principles, pitfalls and (pre-) clinical progress
    • Lammers T., et al. Drug targeting to tumors: Principles, pitfalls and (pre-) clinical progress. J. Control. Release 2012, 161(2):175-187.
    • (2012) J. Control. Release , vol.161 , Issue.2 , pp. 175-187
    • Lammers, T.1
  • 31
    • 0032580354 scopus 로고    scopus 로고
    • Drug Delivery and Targeting
    • Langer R. Drug Delivery and Targeting. Nature 1998, 392:9-10.
    • (1998) Nature , vol.392 , pp. 9-10
    • Langer, R.1
  • 32
    • 72149134615 scopus 로고    scopus 로고
    • Murray's law and the bifurcation angle in the arterial micro-circulation system and their application to the design of microfluidics
    • Lee J., Lee S. Murray's law and the bifurcation angle in the arterial micro-circulation system and their application to the design of microfluidics. Microfluid. Nanofluid. 2010, 8(1):85-95.
    • (2010) Microfluid. Nanofluid. , vol.8 , Issue.1 , pp. 85-95
    • Lee, J.1    Lee, S.2
  • 33
    • 0014699156 scopus 로고
    • Entry flow into blood vessels at arbitrary Reynolds number
    • Lew H.S., Fung Y.C. Entry flow into blood vessels at arbitrary Reynolds number. J. Biomech. 1970, 3(1):23-38.
    • (1970) J. Biomech. , vol.3 , Issue.1 , pp. 23-38
    • Lew, H.S.1    Fung, Y.C.2
  • 35
    • 84865320853 scopus 로고    scopus 로고
    • Computational Modeling of Nanoparticle Targeted Drug Delivery
    • Liu Y., Shah S., Tan J. Computational Modeling of Nanoparticle Targeted Drug Delivery. Rev. Nanosci. Nanotechnol. 2012, 1(1):66-83.
    • (2012) Rev. Nanosci. Nanotechnol. , vol.1 , Issue.1 , pp. 66-83
    • Liu, Y.1    Shah, S.2    Tan, J.3
  • 36
    • 0030472170 scopus 로고    scopus 로고
    • Erythrocyte flow and elasticity of microvessels evaluated by marginal cell-free layer and flow resistance
    • Maeda N., et al. Erythrocyte flow and elasticity of microvessels evaluated by marginal cell-free layer and flow resistance. Am. J. Physiol. Heart Circ. Physiol. 1996, 271(6):H2454-H2461.
    • (1996) Am. J. Physiol. Heart Circ. Physiol. , vol.271 , Issue.6
    • Maeda, N.1
  • 38
    • 0035984039 scopus 로고    scopus 로고
    • Poly(dimethylsiloxane) as a Material for Fabricating Microfluidic Devices
    • McDonald J.C., Whitesides G.M. Poly(dimethylsiloxane) as a Material for Fabricating Microfluidic Devices. Acc. Chem. Res. 2002, 35(7):491-499.
    • (2002) Acc. Chem. Res. , vol.35 , Issue.7 , pp. 491-499
    • McDonald, J.C.1    Whitesides, G.M.2
  • 39
    • 0035027645 scopus 로고    scopus 로고
    • Blood Flow Structure Related to Red Cell Flow: Determinant of Blood Fluidity in Narrow Microvessels
    • McHedlishvili G., Maeda N. Blood Flow Structure Related to Red Cell Flow: Determinant of Blood Fluidity in Narrow Microvessels. Jpn. J. Physiol. 2001, 51(1):19-30.
    • (2001) Jpn. J. Physiol. , vol.51 , Issue.1 , pp. 19-30
    • McHedlishvili, G.1    Maeda, N.2
  • 40
    • 0028881774 scopus 로고
    • Selectin- and integrin-mediated T-lymphocyte rolling and arrest on TNF-alpha-activated endothelium: augmentation by erythrocytes
    • Melder R.J., et al. Selectin- and integrin-mediated T-lymphocyte rolling and arrest on TNF-alpha-activated endothelium: augmentation by erythrocytes. Biophys. J. 1995, 69(5):2131-2138.
    • (1995) Biophys. J. , vol.69 , Issue.5 , pp. 2131-2138
    • Melder, R.J.1
  • 41
    • 21244499298 scopus 로고    scopus 로고
    • TNF-Related Activation-Induced Cytokine Enhances Leukocyte Adhesiveness: Induction of ICAM-1 and VCAM-1 via TNF Receptor-Associated Factor and Protein Kinase C-Dependent NF-κB Activation in Endothelial Cells
    • Min J.-K., et al. TNF-Related Activation-Induced Cytokine Enhances Leukocyte Adhesiveness: Induction of ICAM-1 and VCAM-1 via TNF Receptor-Associated Factor and Protein Kinase C-Dependent NF-κB Activation in Endothelial Cells. J. Immunol. 2005, 175(1):531-540.
    • (2005) J. Immunol. , vol.175 , Issue.1 , pp. 531-540
    • Min, J.-K.1
  • 42
    • 63949085491 scopus 로고    scopus 로고
    • Trimethyl chitosan and its applications in drug delivery
    • Mourya V.K., Inamdar N. Trimethyl chitosan and its applications in drug delivery. J. Mater. Sci. Mater. Med. 2009, 20(5):1057-1079.
    • (2009) J. Mater. Sci. Mater. Med. , vol.20 , Issue.5 , pp. 1057-1079
    • Mourya, V.K.1    Inamdar, N.2
  • 43
    • 33645404162 scopus 로고    scopus 로고
    • Noninvasive Evaluation of Wall Shear Stress on Retinal Microcirculation in Humans
    • Nagaoka T., Yoshida A. Noninvasive Evaluation of Wall Shear Stress on Retinal Microcirculation in Humans. Invest. Ophthalmol. Vis. Sci. 2006, 47(3):1113-1119.
    • (2006) Invest. Ophthalmol. Vis. Sci. , vol.47 , Issue.3 , pp. 1113-1119
    • Nagaoka, T.1    Yoshida, A.2
  • 44
    • 84874404293 scopus 로고    scopus 로고
    • Margination Propensity of Vascular-Targeted Spheres from Blood Flow in a Microfluidic Model of Human Microvessels
    • Namdee K., et al. Margination Propensity of Vascular-Targeted Spheres from Blood Flow in a Microfluidic Model of Human Microvessels. Langmuir 2013, 29(8):2530-2535.
    • (2013) Langmuir , vol.29 , Issue.8 , pp. 2530-2535
    • Namdee, K.1
  • 45
    • 77952011730 scopus 로고    scopus 로고
    • Shear Rate and Hematocrit Effects on the Apparent Diffusivity of Urea in Suspensions of Bovine Erythrocytes
    • Nanne E.E., Aucoin C.P., Leonard E.F. Shear Rate and Hematocrit Effects on the Apparent Diffusivity of Urea in Suspensions of Bovine Erythrocytes. ASAIO J. 2010, 56(3):151-156. 10.1097/MAT.0b013e3181d4ed0f.
    • (2010) ASAIO J. , vol.56 , Issue.3 , pp. 151-156
    • Nanne, E.E.1    Aucoin, C.P.2    Leonard, E.F.3
  • 46
    • 79960815697 scopus 로고    scopus 로고
    • Flow Shear Stress and Atherosclerosis: A Matter of Site Specificity
    • Nigro P., Abe J.-i., Berk B.C. Flow Shear Stress and Atherosclerosis: A Matter of Site Specificity. Antioxid. Redox Signal. 2011, 15(5):1405-1414.
    • (2011) Antioxid. Redox Signal. , vol.15 , Issue.5 , pp. 1405-1414
    • Nigro, P.1    Abe, J.-I.2    Berk, B.C.3
  • 47
    • 84862579971 scopus 로고    scopus 로고
    • Effect of small-molecule-binding affinity on tumor uptake in vivo: A systematic study using a pretargeted bispecific antibody
    • Orcutt K.D., et al. Effect of small-molecule-binding affinity on tumor uptake in vivo: A systematic study using a pretargeted bispecific antibody. Mol. Cancer Ther. 2012, 11(6):1365-1372.
    • (2012) Mol. Cancer Ther. , vol.11 , Issue.6 , pp. 1365-1372
    • Orcutt, K.D.1
  • 48
    • 3843091677 scopus 로고    scopus 로고
    • In situ forming parenteral drug delivery systems: an overview
    • Packhaeuser C.B., et al. In situ forming parenteral drug delivery systems: an overview. Eur. J. Pharm. Biopharm. 2004, 58(2):445-455.
    • (2004) Eur. J. Pharm. Biopharm. , vol.58 , Issue.2 , pp. 445-455
    • Packhaeuser, C.B.1
  • 49
    • 0036554863 scopus 로고    scopus 로고
    • Anti-HER2 Immunoliposomes: Enhanced Efficacy Attributable to Targeted Delivery
    • Park J.W., et al. Anti-HER2 Immunoliposomes: Enhanced Efficacy Attributable to Targeted Delivery. Clin. Cancer Res. 2002, 8(4):1172-1181.
    • (2002) Clin. Cancer Res. , vol.8 , Issue.4 , pp. 1172-1181
    • Park, J.W.1
  • 51
    • 79959843642 scopus 로고    scopus 로고
    • Bifurcations: Focal Points of Particle Adhesion in Microvascular Networks
    • Prabhakarpandian B., et al. Bifurcations: Focal Points of Particle Adhesion in Microvascular Networks. Microcirculation 2011, 18(5):380-389.
    • (2011) Microcirculation , vol.18 , Issue.5 , pp. 380-389
    • Prabhakarpandian, B.1
  • 52
    • 0028875845 scopus 로고
    • Structure and hemodynamics of microvascular networks: heterogeneity and correlations
    • Pries A.R., Secomb T.W., Gaehtgens P. Structure and hemodynamics of microvascular networks: heterogeneity and correlations. Am. J. Physiol. Heart Circ. Physiol. 1995, 269(5):H1713-H1722.
    • (1995) Am. J. Physiol. Heart Circ. Physiol. , vol.269 , Issue.5
    • Pries, A.R.1    Secomb, T.W.2    Gaehtgens, P.3
  • 53
    • 0030271188 scopus 로고    scopus 로고
    • Biophysical aspects of blood flow in the microvasculature
    • Pries A.R., Secomb T.W., Gaehtgens P. Biophysical aspects of blood flow in the microvasculature. Cardiovasc. Res. 1996, 32(4):654-667.
    • (1996) Cardiovasc. Res. , vol.32 , Issue.4 , pp. 654-667
    • Pries, A.R.1    Secomb, T.W.2    Gaehtgens, P.3
  • 54
    • 78049452610 scopus 로고    scopus 로고
    • Delivering nanomedicine to solid tumors
    • Rakesh K.J., Triantafyllos S. Delivering nanomedicine to solid tumors. Nat. Rev. Clin. Oncol. 2010, 7(11):653-664.
    • (2010) Nat. Rev. Clin. Oncol. , vol.7 , Issue.11 , pp. 653-664
    • Rakesh, K.J.1    Triantafyllos, S.2
  • 55
    • 0022552776 scopus 로고
    • Effect of shear rate variation on apparent viscosity of human blood in tubes of 29 to 94 microns diameter
    • Reinke W., Johnson P., Gaehtgens P. Effect of shear rate variation on apparent viscosity of human blood in tubes of 29 to 94 microns diameter. Circ. Res. 1986, 59(2):124-132.
    • (1986) Circ. Res. , vol.59 , Issue.2 , pp. 124-132
    • Reinke, W.1    Johnson, P.2    Gaehtgens, P.3
  • 56
    • 0015275666 scopus 로고
    • Ratio of red cell velocities near the vessel wall to velocities at the vessel center in cerebral microcirculation, and an apparent effect of blood viscosity on this ratio
    • Rosenblum William I. Ratio of red cell velocities near the vessel wall to velocities at the vessel center in cerebral microcirculation, and an apparent effect of blood viscosity on this ratio. Microvasc. Res. 1972, 4(1):98-101.
    • (1972) Microvasc. Res. , vol.4 , Issue.1 , pp. 98-101
    • Rosenblum, W.I.1
  • 57
    • 0001363338 scopus 로고
    • Behaviour of macroscopic rigid spheres in Poiseuille flow Part 2. Experimental results and interpretation
    • Segré G., Silberberg A. Behaviour of macroscopic rigid spheres in Poiseuille flow Part 2. Experimental results and interpretation. J. Fluid Mech. 1962, 14(01):136-157.
    • (1962) J. Fluid Mech. , vol.14 , Issue.1 , pp. 136-157
    • Segré, G.1    Silberberg, A.2
  • 58
    • 79952852964 scopus 로고    scopus 로고
    • Modeling Particle Shape-Dependent Dynamics in Nanomedicine
    • Shah S., et al. Modeling Particle Shape-Dependent Dynamics in Nanomedicine. J. Nanosci. Nanotechnol. 2011, 11(2):919-928.
    • (2011) J. Nanosci. Nanotechnol. , vol.11 , Issue.2 , pp. 919-928
    • Shah, S.1
  • 60
    • 67349179610 scopus 로고    scopus 로고
    • Nanoparticle-based targeted drug delivery
    • Singh R., Lillard J.W. Nanoparticle-based targeted drug delivery. Exp. Mol. Pathol. 2009, 86(3):215-223.
    • (2009) Exp. Mol. Pathol. , vol.86 , Issue.3 , pp. 215-223
    • Singh, R.1    Lillard, J.W.2
  • 61
    • 33845946525 scopus 로고    scopus 로고
    • Determination of shear viscosity and shear rate from pressure drop and flow rate relationship in a rectangular channel
    • Son Y. Determination of shear viscosity and shear rate from pressure drop and flow rate relationship in a rectangular channel. Polymer 2007, 48(2):632-637.
    • (2007) Polymer , vol.48 , Issue.2 , pp. 632-637
    • Son, Y.1
  • 62
  • 63
    • 84863012606 scopus 로고    scopus 로고
    • Influence of red blood cells on nanoparticle targeted delivery in microcirculation
    • Tan J., Thomas A., Liu Y. Influence of red blood cells on nanoparticle targeted delivery in microcirculation. Soft Matter 2012, 8(6):1934-1946.
    • (2012) Soft Matter , vol.8 , Issue.6 , pp. 1934-1946
    • Tan, J.1    Thomas, A.2    Liu, Y.3
  • 64
    • 84878595723 scopus 로고    scopus 로고
    • The influence of size, shape and vessel geometry on nanoparticle distribution
    • Tan J., et al. The influence of size, shape and vessel geometry on nanoparticle distribution. Microfluid. Nanofluid. 2013, 14(1-2):77-87.
    • (2013) Microfluid. Nanofluid. , vol.14 , Issue.1-2 , pp. 77-87
    • Tan, J.1
  • 65
    • 84878359213 scopus 로고    scopus 로고
    • Coupled particulate and continuum model for nanoparticle targeted delivery
    • Tan J., et al. Coupled particulate and continuum model for nanoparticle targeted delivery. Comput. Struct. 2013, 122(0):128-134.
    • (2013) Comput. Struct. , vol.122 , Issue.0 , pp. 128-134
    • Tan, J.1
  • 66
    • 34249820576 scopus 로고    scopus 로고
    • Multifunctional nanocarriers
    • Torchilin V.P. Multifunctional nanocarriers. Adv. Drug Deliv. Rev. 2006, 58(14):1532-1555.
    • (2006) Adv. Drug Deliv. Rev. , vol.58 , Issue.14 , pp. 1532-1555
    • Torchilin, V.P.1
  • 67
    • 26944462655 scopus 로고    scopus 로고
    • Migration of a sphere in tube flow
    • Yang B.H., et al. Migration of a sphere in tube flow. J. Fluid Mech. 2005, 540:109-131.
    • (2005) J. Fluid Mech. , vol.540 , pp. 109-131
    • Yang, B.H.1
  • 68
    • 0036000323 scopus 로고    scopus 로고
    • In vivo PIV measurement of red blood cell velocity field in microvessels considering mesentery motion
    • Yasuhiko Sugii, Nishio Shigeru, Okamoto Koji In vivo PIV measurement of red blood cell velocity field in microvessels considering mesentery motion. Physiol. Meas. 2002, 23(2).
    • (2002) Physiol. Meas. , vol.23 , Issue.2
    • Yasuhiko, S.1    Nishio, S.2    Okamoto, K.3
  • 69
    • 0018235164 scopus 로고
    • Effect of velocity of distribution on red cell distribution in capillary blood vessels
    • Yen R.T., Fung Y.C. Effect of velocity of distribution on red cell distribution in capillary blood vessels. Am. J. Physiol. 1978, 09:H251-H257.
    • (1978) Am. J. Physiol. , vol.9
    • Yen, R.T.1    Fung, Y.C.2
  • 70
    • 0032530318 scopus 로고    scopus 로고
    • LIGHT, a novel ligand for lymphotoxin beta receptor and TR2/HVEM induces apoptosis and suppresses in vivo tumor formation via gene transfer
    • Zhai Y., et al. LIGHT, a novel ligand for lymphotoxin beta receptor and TR2/HVEM induces apoptosis and suppresses in vivo tumor formation via gene transfer. J. Clin. Invest. 1998, 102(6):1142-1151.
    • (1998) J. Clin. Invest. , vol.102 , Issue.6 , pp. 1142-1151
    • Zhai, Y.1
  • 71
    • 12344301305 scopus 로고    scopus 로고
    • Comparison of micro- and nano-size particle depositions in a human upper airway model
    • Zhang Z., Kleinstreuer C., Donohue J.F., Kim C.S. Comparison of micro- and nano-size particle depositions in a human upper airway model. J. Aerosol Sci. 2005, 36:211-233.
    • (2005) J. Aerosol Sci. , vol.36 , pp. 211-233
    • Zhang, Z.1    Kleinstreuer, C.2    Donohue, J.F.3    Kim, C.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.