Maternal pregravid obesity changes gene expression profiles toward greater inflammation and reduced insulin sensitivity in umbilical cord

Pediatric Research

Volumn 76, Issue 2, 2014, Pages 202-210

  Thakali, Keshari M ^a,b   Saben, Jessica ^a,b   Faske, Jennifer B ^a   Lindsey, Forrest ^a   Gomez Acevedo, Horacio ^a,b   Lowery Jr , Curtis L ^b   Badger, Thomas M ^a,b   Andres, Aline ^a,b   Shankar, Kartik ^a,b  

^a ARKANSAS CHILDREN S HOSPITAL   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EARLY GROWTH RESPONSE FACTOR 1; ENDOTHELIN RECEPTOR; INSULIN; KRUEPPEL LIKE FACTOR 10; KRUPPEL LIKE FACTOR; LEPTIN; MESSENGER RNA; SUPPRESSOR OF CYTOKINE SIGNALING 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EGLN3; TRANSCRIPTION FACTOR FOSB; TRANSCRIPTION FACTOR MEST; TRANSCRIPTION FACTOR PEG3; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; CELL ADHESION MOLECULE; EGR1 PROTEIN, HUMAN; FOSB PROTEIN, HUMAN; POSTN PROTEIN, HUMAN; PRIMER DNA; PROTEIN C FOS;

ADULT; ARTICLE; BODY FAT; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FAT MASS; FEMALE; FIRST TRIMESTER PREGNANCY; GENE EXPRESSION ASSAY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; HORMONE BLOOD LEVEL; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULIN SIGNALING; MATERNAL OBESITY; MICROARRAY ANALYSIS; PREGNANCY DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UMBILICAL CORD; ANALYSIS OF VARIANCE; ANTHROPOMETRY; BLOOD; COMPARATIVE STUDY; GENETICS; MATERNAL NUTRITION; METABOLISM; OBESITY; PATHOPHYSIOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING;

ADIPOSITY; ADULT; ANALYSIS OF VARIANCE; ANTHROPOMETRY; BLOTTING, WESTERN; CELL ADHESION MOLECULES; DNA PRIMERS; EARLY GROWTH RESPONSE PROTEIN 1; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INFLAMMATION; INSULIN; INSULIN RESISTANCE; LEPTIN; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; MICROARRAY ANALYSIS; OBESITY; PROTO-ONCOGENE PROTEINS C-FOS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; UMBILICAL CORD;

EID: 84904611580     PISSN: 00313998     EISSN: 15300447     Source Type: Journal    
DOI: 10.1038/pr.2014.72     Document Type: Article

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