메뉴 건너뛰기




Volumn 5 MAY, Issue , 2014, Pages

Maintenance of glutathione levels and its importance in epigenetic regulation

Author keywords

DNA methylation; Epigenetic regulation; Glutathione; Glutathionylation; Mental disorders; Prodrugs; S adenosyl methionine

Indexed keywords

ASCORBIC ACID; DNA; DNA METHYLTRANSFERASE; DOXORUBICIN; GLUTAREDOXIN; GLUTATHIONE; GLUTATHIONE DISULFIDE; HISTONE H3; HISTONE METHYLTRANSFERASE; HOMOCYSTEINE; METHIONINE; METHIONINE ADENOSYLTRANSFERASE; METHIONINE ADENOSYLTRANSFERASE 1A; METHIONINE SULFOXIDE; METHIONINE SULFOXIDE REDUCTASE; METHIONINE SYNTHASE; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG;

EID: 84904610478     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2014.00088     Document Type: Note
Times cited : (37)

References (28)
  • 1
    • 0032435767 scopus 로고    scopus 로고
    • Glutathione therapy: from prodrugs to genes
    • doi: 10.1055/s-2007-1007174
    • Anderson, M. E., and Luo, J. L. (1998). Glutathione therapy: from prodrugs to genes. Semin. Liver Dis. 18, 415-424. doi: 10.1055/s-2007-1007174.
    • (1998) Semin. Liver Dis , vol.18 , pp. 415-424
    • Anderson, M.E.1    Luo, J.L.2
  • 2
    • 77950343169 scopus 로고    scopus 로고
    • Prodrug approach for increasing cellular glutathione levels
    • doi: 10.3390/molecules15031242
    • Cacciatore, I., Cornacchia, C., Pinnen, F., Mollica, A., and Di Stefano, A. (2010). Prodrug approach for increasing cellular glutathione levels. Molecules 15, 1242-1264. doi: 10.3390/molecules15031242.
    • (2010) Molecules , vol.15 , pp. 1242-1264
    • Cacciatore, I.1    Cornacchia, C.2    Pinnen, F.3    Mollica, A.4    Di Stefano, A.5
  • 3
    • 0028864634 scopus 로고
    • Cerebrospinal fluid S-adenosylmethionine (SAMe) and glutathione concentrations in HIV infection: effect of parenteral treatment with SAMe
    • doi: 10.1212/WNL.45.9.1678
    • Castagna, A., Le Grazie, C., Accordini, A., Giulidori, P., Cavalli, G., Bottiglieri, T., et al. (1995). Cerebrospinal fluid S-adenosylmethionine (SAMe) and glutathione concentrations in HIV infection: effect of parenteral treatment with SAMe. Neurology 45, 1678-1683. doi: 10.1212/WNL.45.9.1678.
    • (1995) Neurology , vol.45 , pp. 1678-1683
    • Castagna, A.1    Le Grazie, C.2    Accordini, A.3    Giulidori, P.4    Cavalli, G.5    Bottiglieri, T.6
  • 4
    • 84888372386 scopus 로고    scopus 로고
    • Vitamin C modulates TET1 function during somatic cell reprogramming
    • doi: 10.1038/ng.2807
    • Chen, J., Guo, L., Zhang, L., Wu, H., Yang, J., Liu, H., et al. (2013). Vitamin C modulates TET1 function during somatic cell reprogramming. Nat. Genet. 45, 1504-1509. doi: 10.1038/ng.2807.
    • (2013) Nat. Genet , vol.45 , pp. 1504-1509
    • Chen, J.1    Guo, L.2    Zhang, L.3    Wu, H.4    Yang, J.5    Liu, H.6
  • 5
    • 81155154369 scopus 로고    scopus 로고
    • Treatment of doxorubicin-resistant MCF7/Dx cells with nitric oxide causes histone glutathionylation and reversal of drug resistance
    • doi: 10.1042/BJ20111333
    • de Luca, A., Moroni, N., Serafino, A., Primavera, A., Pastore, A., Pedersen, J. Z., et al. (2011). Treatment of doxorubicin-resistant MCF7/Dx cells with nitric oxide causes histone glutathionylation and reversal of drug resistance. Biochem. J. 440, 175-183. doi: 10.1042/BJ20111333.
    • (2011) Biochem. J , vol.440 , pp. 175-183
    • de Luca, A.1    Moroni, N.2    Serafino, A.3    Primavera, A.4    Pastore, A.5    Pedersen, J.Z.6
  • 6
    • 34347222214 scopus 로고    scopus 로고
    • Design, synthesis and properties of novel powerful antioxidants, glutathione analogues
    • doi: 10.1080/10715760701348611
    • Ehrlich, K., Viirlaid, S., Mahlapuu, R., Saar, K., Kullisaar, T., Zilmer, M., et al. (2007). Design, synthesis and properties of novel powerful antioxidants, glutathione analogues. Free Radic. Res. 41, 779-787. doi: 10.1080/10715760701348611.
    • (2007) Free Radic. Res , vol.41 , pp. 779-787
    • Ehrlich, K.1    Viirlaid, S.2    Mahlapuu, R.3    Saar, K.4    Kullisaar, T.5    Zilmer, M.6
  • 9
    • 84881478663 scopus 로고    scopus 로고
    • Histone h3 glutathionylation in proliferating mammalian cells destabilizes nucleosomal structure
    • doi: 10.1089/ars.2012.5021
    • García-Giménez, J. L., Olaso, G., Hake, S. B., Bonisch, C., Wiedemann, S. M., Markovic, J., et al. (2013b). Histone h3 glutathionylation in proliferating mammalian cells destabilizes nucleosomal structure. Antioxid. Redox Signal. 19, 1305-1320. doi: 10.1089/ars.2012.5021.
    • (2013) Antioxid. Redox Signal , vol.19 , pp. 1305-1320
    • García-Giménez, J.L.1    Olaso, G.2    Hake, S.B.3    Bonisch, C.4    Wiedemann, S.M.5    Markovic, J.6
  • 10
    • 15244348759 scopus 로고    scopus 로고
    • Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism
    • James, S. J., Cutler, P., Melnyk, S., Jernigan, S., Janak, L., Gaylor, D. W., et al. (2004). Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism. Am. J. Clin. Nutr. 80, 1611-1617.
    • (2004) Am. J. Clin. Nutr , vol.80 , pp. 1611-1617
    • James, S.J.1    Cutler, P.2    Melnyk, S.3    Jernigan, S.4    Janak, L.5    Gaylor, D.W.6
  • 11
    • 33845438146 scopus 로고    scopus 로고
    • Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism
    • doi: 10.1002/ajmg.b.30366
    • James, S. J., Melnyk, S., Jernigan, S., Cleves, M. A., Halsted, C. H., Wong, D. H., et al. (2006). Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism. Am. J. Med. Genet. B Neuropsychiatr. Genet. 141B, 947-956. doi: 10.1002/ajmg.b.30366.
    • (2006) Am. J. Med. Genet. B Neuropsychiatr. Genet , vol.141 , pp. 947-956
    • James, S.J.1    Melnyk, S.2    Jernigan, S.3    Cleves, M.A.4    Halsted, C.H.5    Wong, D.H.6
  • 12
    • 72049121173 scopus 로고    scopus 로고
    • DNA methylation by dimethyl sulfoxide and methionine sulfoxide triggered by hydroxyl radical and implications for epigenetic modifications
    • doi: 10.1016/j.bmcl.2009.10.124
    • Kawai, K., Li, Y. S., Song, M. F., and Kasai, H. (2010). DNA methylation by dimethyl sulfoxide and methionine sulfoxide triggered by hydroxyl radical and implications for epigenetic modifications. Bioorg. Med. Chem. Lett. 20, 260-265. doi: 10.1016/j.bmcl.2009.10.124.
    • (2010) Bioorg. Med. Chem. Lett , vol.20 , pp. 260-265
    • Kawai, K.1    Li, Y.S.2    Song, M.F.3    Kasai, H.4
  • 13
    • 84863430482 scopus 로고    scopus 로고
    • Glutaredoxin serves as a reductant for methionine sulfoxide reductases with or without resolving cysteine
    • doi: 10.1093/abbs/gms038
    • Kim, H. Y. (2012). Glutaredoxin serves as a reductant for methionine sulfoxide reductases with or without resolving cysteine. Acta Biochim. Biophys. Sin. 44, 623-627. doi: 10.1093/abbs/gms038.
    • (2012) Acta Biochim. Biophys. Sin , vol.44 , pp. 623-627
    • Kim, H.Y.1
  • 14
    • 40849116456 scopus 로고    scopus 로고
    • Aberrant DNA methylation associated with bipolar disorder identified from discordant monozygotic twins
    • doi: 10.1038/sj.mp.4002001
    • Kuratomi, G., Iwamoto, K., Bundo, M., Kusumi, I., Kato, N., Iwata, N., et al. (2008). Aberrant DNA methylation associated with bipolar disorder identified from discordant monozygotic twins. Mol. Psychiatry 13, 429-441. doi: 10.1038/sj.mp.4002001.
    • (2008) Mol. Psychiatry , vol.13 , pp. 429-441
    • Kuratomi, G.1    Iwamoto, K.2    Bundo, M.3    Kusumi, I.4    Kato, N.5    Iwata, N.6
  • 15
    • 79959744436 scopus 로고    scopus 로고
    • DNA methylation in cancer development, diagnosis and therapy-multiple opportunities for genotoxic agents to act as methylome disruptors or remediators
    • doi: 10.1093/mutage/ger019
    • Lewandowska, J., and Bartoszek, A. (2011). DNA methylation in cancer development, diagnosis and therapy-multiple opportunities for genotoxic agents to act as methylome disruptors or remediators. Mutagenesis 26, 475-487. doi: 10.1093/mutage/ger019.
    • (2011) Mutagenesis , vol.26 , pp. 475-487
    • Lewandowska, J.1    Bartoszek, A.2
  • 17
    • 0030592716 scopus 로고    scopus 로고
    • Role of thioltransferases on the modulation of rat liver S-adenosylmethionine synthetase activity by glutathione
    • doi: 10.1016/S0014-5793(96)01201-X
    • Martinez-Chantar, M. L., and Pajares, M. A. (1996). Role of thioltransferases on the modulation of rat liver S-adenosylmethionine synthetase activity by glutathione. FEBS Lett. 397, 293-297. doi: 10.1016/S0014-5793(96)01201-X.
    • (1996) FEBS Lett , vol.397 , pp. 293-297
    • Martinez-Chantar, M.L.1    Pajares, M.A.2
  • 18
    • 0036136732 scopus 로고    scopus 로고
    • S-Adenosylmethionine: a control switch that regulates liver function
    • doi: 10.1096/fj.01-0401rev
    • Mato, J. M., Corrales, F. J., Lu, S. C., and Avila, M. A. (2002). S-Adenosylmethionine: a control switch that regulates liver function. FASEB J. 16, 15-26. doi: 10.1096/fj.01-0401rev.
    • (2002) FASEB J , vol.16 , pp. 15-26
    • Mato, J.M.1    Corrales, F.J.2    Lu, S.C.3    Avila, M.A.4
  • 19
    • 84877693964 scopus 로고    scopus 로고
    • Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine
    • doi: 10.1074/jbc.C113.464800
    • Minor, E. A., Court, B. L., Young, J. I., and Wang, G. (2013). Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine. J. Biol. Chem. 288, 13669-13674. doi: 10.1074/jbc.C113.464800.
    • (2013) J. Biol. Chem , vol.288 , pp. 13669-13674
    • Minor, E.A.1    Court, B.L.2    Young, J.I.3    Wang, G.4
  • 20
    • 84874242535 scopus 로고    scopus 로고
    • Age-dependent decrease and alternative splicing of methionine synthase mRNA in human cerebral cortex and an accelerated decrease in autism
    • doi: 10.1371/journal.pone.0056927
    • Muratore, C. R., Hodgson, N. W., Trivedi, M. S., Abdolmaleky, H. M., Persico, A. M., Lintas, C., et al. (2013). Age-dependent decrease and alternative splicing of methionine synthase mRNA in human cerebral cortex and an accelerated decrease in autism. PLoS ONE 8:e56927. doi: 10.1371/journal.pone.0056927.
    • (2013) PLoS ONE , vol.8
    • Muratore, C.R.1    Hodgson, N.W.2    Trivedi, M.S.3    Abdolmaleky, H.M.4    Persico, A.M.5    Lintas, C.6
  • 21
    • 84867910751 scopus 로고    scopus 로고
    • Methionine synthase deficiency: a rare cause of adult-onset leukoencephalopathy
    • doi: 10.1212/WNL.0b013e318260451b
    • Outteryck, O., de Seze, J., Stojkovic, T., Cuisset, J. M., Dobbelaere, D., Delalande, S., et al. (2012). Methionine synthase deficiency: a rare cause of adult-onset leukoencephalopathy. Neurology 79, 386-388. doi: 10.1212/WNL.0b013e318260451b.
    • (2012) Neurology , vol.79 , pp. 386-388
    • Outteryck, O.1    de Seze, J.2    Stojkovic, T.3    Cuisset, J.M.4    Dobbelaere, D.5    Delalande, S.6
  • 22
    • 0026699645 scopus 로고
    • Modulation of rat liver S-adenosylmethionine synthetase activity by glutathione
    • Pajares, M. A., Duran, C., Corrales, F., Pliego, M. M., and Mato, J. M. (1992). Modulation of rat liver S-adenosylmethionine synthetase activity by glutathione. J. Biol. Chem. 267, 17598-17605.
    • (1992) J. Biol. Chem , vol.267 , pp. 17598-17605
    • Pajares, M.A.1    Duran, C.2    Corrales, F.3    Pliego, M.M.4    Mato, J.M.5
  • 23
    • 65049087578 scopus 로고    scopus 로고
    • Role of nuclear glutathione as a key regulator of cell proliferation
    • doi: 10.1016/j.mam.2009.01.001
    • Pallardó, F. V., Markovic, J., Garcia, J. L., and Viña, J. (2009). Role of nuclear glutathione as a key regulator of cell proliferation. Mol. Aspects Med. 30, 77-85. doi: 10.1016/j.mam.2009.01.001.
    • (2009) Mol. Aspects Med , vol.30 , pp. 77-85
    • Pallardó, F.V.1    Markovic, J.2    Garcia, J.L.3    Viña, J.4
  • 24
    • 0028564741 scopus 로고
    • Homocysteinemia and schizophrenia as a case of methylation deficiency
    • doi: 10.1007/BF01277017
    • Regland, B., Johansson, B. V., and Gottfries, C. G. (1994). Homocysteinemia and schizophrenia as a case of methylation deficiency. J. Neural Transm. Gen. Sect. 98, 143-152. doi: 10.1007/BF01277017.
    • (1994) J. Neural Transm. Gen. Sect , vol.98 , pp. 143-152
    • Regland, B.1    Johansson, B.V.2    Gottfries, C.G.3
  • 25
    • 0025356938 scopus 로고
    • Synthesis of cyclic peptide homologs of glutathione as potential antitumor agents
    • doi: 10.1111/j.1399-3011.1990.tb00721.x
    • Sheh, L., Chen, B. L., and Chen, C. F. (1990). Synthesis of cyclic peptide homologs of glutathione as potential antitumor agents. Int. J. Pept. Protein Res. 35, 55-62. doi: 10.1111/j.1399-3011.1990.tb00721.x.
    • (1990) Int. J. Pept. Protein Res , vol.35 , pp. 55-62
    • Sheh, L.1    Chen, B.L.2    Chen, C.F.3
  • 26
    • 0028917918 scopus 로고
    • Glutathione protects against hypoxic/hypoglycemic decreases in 2-deoxyglucose uptake and presynaptic spikes in hippocampal slices
    • doi: 10.1016/0014-2999(94)00727-O
    • Shibata, S., Tominaga, K., and Watanabe, S. (1995). Glutathione protects against hypoxic/hypoglycemic decreases in 2-deoxyglucose uptake and presynaptic spikes in hippocampal slices. Eur. J. Pharmacol. 273, 191-195. doi: 10.1016/0014-2999(94)00727-O.
    • (1995) Eur. J. Pharmacol , vol.273 , pp. 191-195
    • Shibata, S.1    Tominaga, K.2    Watanabe, S.3
  • 27
    • 84875723942 scopus 로고    scopus 로고
    • Glutathione and glutathione analogues; therapeutic potentials
    • doi: 10.1016/j.bbagen.2012.11.016
    • Wu, J. H., and Batist, G. (2013). Glutathione and glutathione analogues; therapeutic potentials. Biochim. Biophys. Acta 1830, 3350-3353. doi: 10.1016/j.bbagen.2012.11.016.
    • (2013) Biochim. Biophys. Acta , vol.1830 , pp. 3350-3353
    • Wu, J.H.1    Batist, G.2
  • 28
    • 29244464827 scopus 로고    scopus 로고
    • Altered glutathione redox state in schizophrenia
    • doi: 10.1155/2006/248387
    • Yao, J. K., Leonard, S., and Reddy, R. (2006). Altered glutathione redox state in schizophrenia. Dis. Markers 22, 83-93. doi: 10.1155/2006/248387.
    • (2006) Dis. Markers , vol.22 , pp. 83-93
    • Yao, J.K.1    Leonard, S.2    Reddy, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.