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Volumn 6, Issue JUL, 2014, Pages

Genetic variation modifies risk for neurodegeneration based on biomarker status

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; BIOLOGICAL MARKER; TAU PROTEIN; AMYLOID BETA PROTEIN[1-42]; SERINE PALMITOYLTRANSFERASE; SERINE PALMITOYLTRANSFERASE LONG CHAIN BASE SUBUNIT 1; UNCLASSIFIED DRUG;

EID: 84904610217     PISSN: None     EISSN: 16634365     Source Type: Journal    
DOI: 10.3389/fnagi.2014.00183     Document Type: Article
Times cited : (18)

References (47)
  • 1
    • 0346124139 scopus 로고    scopus 로고
    • Cerebrospinal fluid tau and beta-amyloid: how well do these biomarkers reflect autopsy-confirmed dementia diagnoses?
    • Clark, C., Xie, S., Chittams, J., Ewbank, D., Peskind, E., et al. (2003). Cerebrospinal fluid tau and beta-amyloid: how well do these biomarkers reflect autopsy-confirmed dementia diagnoses? Archives of Neurology, 60(12), 1696-1702.
    • (2003) Archives of Neurology , vol.60 , Issue.12 , pp. 1696-1702
    • Clark, C.1    Xie, S.2    Chittams, J.3    Ewbank, D.4    Peskind, E.5
  • 5
    • 0035093829 scopus 로고    scopus 로고
    • Mutations in SPTLC1, encoding serine palmitoyltransferase, long chain base subunit- 1, cause hereditary sensory neuropathy type I
    • Dawkins, J. L., Hulme, D. J., Brahmbhatt, S. B., Auer-Grumbach, M., & Nicholson, G. A. (2001). Mutations in SPTLC1, encoding serine palmitoyltransferase, long chain base subunit- 1, cause hereditary sensory neuropathy type I. Nature genetics, 27, 309-312.
    • (2001) Nature genetics , vol.27 , pp. 309-312
    • Dawkins, J.L.1    Hulme, D.J.2    Brahmbhatt, S.B.3    Auer-Grumbach, M.4    Nicholson, G.A.5
  • 6
    • 33746932485 scopus 로고    scopus 로고
    • An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest
    • Desikan, R. S., Segonne, F., Fischl, B., Quinn, B. T., Dickerson, B. C., Blacker, D. et al. (2006). An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. Neuroimage, 31, 968-980.
    • (2006) Neuroimage , vol.31 , pp. 968-980
    • Desikan, R.S.1    Segonne, F.2    Fischl, B.3    Quinn, B.T.4    Dickerson, B.C.5    Blacker, D.6
  • 7
    • 62549122091 scopus 로고    scopus 로고
    • Decreased cerebrospinal fluid Aβ42 correlates with brain atrophy in cognitively normal elderly
    • Fagan, A. M., Head, D., Shah, A. R., Marcus, D., Mintun, M., Morris, J. C. et al. (2009). Decreased cerebrospinal fluid Aβ42 correlates with brain atrophy in cognitively normal elderly. Annals of neurology, 65, 176-183.
    • (2009) Annals of neurology , vol.65 , pp. 176-183
    • Fagan, A.M.1    Head, D.2    Shah, A.R.3    Marcus, D.4    Mintun, M.5    Morris, J.C.6
  • 9
    • 0032799993 scopus 로고    scopus 로고
    • Cortical surface-based analysis
    • Fischl, B., Sereno, M. I., & Dale, A. M. (1999a). Cortical surface-based analysis. Neuroimage, 9, 195-207.
    • (1999) Neuroimage , vol.9 , pp. 195-207
    • Fischl, B.1    Sereno, M.I.2    Dale, A.M.3
  • 10
    • 0032799993 scopus 로고    scopus 로고
    • Cortical Surface-Based Analysis: II: Inflation, Flattening, and a Surface-Based Coordinate System
    • Fischl, B., Sereno, M. I., & Dale, A. M. (1999b). Cortical Surface-Based Analysis: II: Inflation, Flattening, and a Surface-Based Coordinate System. Neuroimage, 9, 195-207.
    • (1999) Neuroimage , vol.9 , pp. 195-207
    • Fischl, B.1    Sereno, M.I.2    Dale, A.M.3
  • 11
    • 0032741345 scopus 로고    scopus 로고
    • High-resolution intersubject averaging and a coordinate system for the cortical surface
    • Fischl, B., Sereno, M. I., Tootell, R. B., & Dale, A. M. (1999). High-resolution intersubject averaging and a coordinate system for the cortical surface. Human brain mapping, 8, 272-284.
    • (1999) Human brain mapping , vol.8 , pp. 272-284
    • Fischl, B.1    Sereno, M.I.2    Tootell, R.B.3    Dale, A.M.4
  • 13
    • 84895536249 scopus 로고    scopus 로고
    • Mitochondrial ferritin in the regulation of brain iron homeostasis and neurodegenerative diseases
    • Gao, G. & Chang, Y. (2014). Mitochondrial ferritin in the regulation of brain iron homeostasis and neurodegenerative diseases. Frontiers in Pharmacology, 17, 5-19.
    • (2014) Frontiers in Pharmacology , vol.17 , pp. 5-19
    • Gao, G.1    Chang, Y.2
  • 14
    • 84894094478 scopus 로고    scopus 로고
    • Epistatic effects among Alzheimer's Candidate Genes
    • Hohman, T. J., Koran, M. I., & Thornton-Wells, T. A. (2013). Epistatic effects among Alzheimer's Candidate Genes. PloS one, 8, e80839.
    • (2013) PloS one , vol.8
    • Hohman, T.J.1    Koran, M.I.2    Thornton-Wells, T.A.3
  • 15
    • 84927176584 scopus 로고    scopus 로고
    • Genetic Modification of the Relationship between Phosphorylated Tau and Neurodegeneration
    • Hohman, T. J., Koran, M. I., & Thornton-Wells, T. A. (2014a). Genetic Modification of the Relationship between Phosphorylated Tau and Neurodegeneration. Alzheimer's & Dementia.
    • (2014) Alzheimer's & Dementia.
    • Hohman, T.J.1    Koran, M.I.2    Thornton-Wells, T.A.3
  • 16
    • 84889575830 scopus 로고    scopus 로고
    • Interactions between GSK3B and amyloid genes explain variance in amyloid burden
    • Hohman, T. J., Koran, M. E., & Thornton-Wells, T. A. (2014b). Interactions between GSK3B and amyloid genes explain variance in amyloid burden. Neurobiology of Aging, 35, 460- 465.
    • (2014) Neurobiology of Aging , vol.35
    • Hohman, T.J.1    Koran, M.E.2    Thornton-Wells, T.A.3
  • 18
    • 84872379077 scopus 로고    scopus 로고
    • Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
    • Jack Jr, C. R., Knopman, D. S., Jagust, W. J., Petersen, R. C., Weiner, M. W., Aisen, P. S. et al. (2013). Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers. The Lancet Neurology, 12, 207-216.
    • (2013) The Lancet Neurology , vol.12 , pp. 207-216
    • Jack Jr, C.R.1    Knopman, D.S.2    Jagust, W.J.3    Petersen, R.C.4    Weiner, M.W.5    Aisen, P.S.6
  • 21
    • 77957739987 scopus 로고    scopus 로고
    • WDR11, a WD protein that interacts with transcription factor EMX1, is mutated in idiopathic hypogonadotropic hypogonadism and Kallmann syndrome
    • Kim, H. G., Ahn, J. W., Kurth, I., Ullmann, R., Kim, H. T., Kulharya, A. et al. (2010). WDR11, a WD protein that interacts with transcription factor EMX1, is mutated in idiopathic hypogonadotropic hypogonadism and Kallmann syndrome. The American Journal of Human Genetics, 87, 465-479.
    • (2010) The American Journal of Human Genetics , vol.87 , pp. 465-479
    • Kim, H.G.1    Ahn, J.W.2    Kurth, I.3    Ullmann, R.4    Kim, H.T.5    Kulharya, A.6
  • 22
    • 78751635081 scopus 로고    scopus 로고
    • Genome-wide association study of CSF biomarkers Abeta-42, t-tau, and p-tau181p in the ADNI cohort
    • Kim, S., Swaminathan, S., Shen, L., Risacher, S. L., Nho, K., Foroud, T. et al. (2011). Genome-wide association study of CSF biomarkers Abeta-42, t-tau, and p-tau181p in the ADNI cohort. Neurology, 76, 69-79.
    • (2011) Neurology , vol.76 , pp. 69-79
    • Kim, S.1    Swaminathan, S.2    Shen, L.3    Risacher, S.L.4    Nho, K.5    Foroud, T.6
  • 23
    • 84887221030 scopus 로고    scopus 로고
    • Genetic interactions within inositol-related pathways are associated with longitudinal changes in ventricle size
    • Koran, M. I., Hohman, T. J., Meda, S. A., & Thornton-Wells, T. (2014). Genetic interactions within inositol-related pathways are associated with longitudinal changes in ventricle size. Journal of Alzheimer's Disease, 38, 145-154.
    • (2014) Journal of Alzheimer's Disease , vol.38 , pp. 145-154
    • Koran, M.I.1    Hohman, T.J.2    Meda, S.A.3    Thornton-Wells, T.4
  • 24
    • 84891869466 scopus 로고    scopus 로고
    • Genetic interactions found between calcium channel genes modulate amyloid load measured by positron emission tomography
    • Koran, M. I., Hohman, T. J., & Thornton-Wells, T. A. (2014). Genetic interactions found between calcium channel genes modulate amyloid load measured by positron emission tomography. Hum Genet, 133, 85-93.
    • (2014) Hum Genet , vol.133 , pp. 85-93
    • Koran, M.I.1    Hohman, T.J.2    Thornton-Wells, T.A.3
  • 25
    • 38349038412 scopus 로고    scopus 로고
    • Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease
    • Li, H., Wetten, S., Li, L., St Jean, P. L., Upmanyu, R., Surh, L. et al. (2008). Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease. Archives of Neurology, 65, 45.
    • (2008) Archives of Neurology , vol.65 , pp. 45
    • Li, H.1    Wetten, S.2    Li, L.3    St Jean, P.L.4    Upmanyu, R.5    Surh, L.6
  • 26
    • 84873438019 scopus 로고    scopus 로고
    • Genetic interactions associated with 12-month atrophy in hippocampus and entorhinal cortex in Alzheimer's Disease Neuroimaging Initiative
    • Meda, S. A., Koran, M. E., Pryweller, J. R., Vega, J. N., & Thornton-Wells, T. A. (2013). Genetic interactions associated with 12-month atrophy in hippocampus and entorhinal cortex in Alzheimer's Disease Neuroimaging Initiative. Neurobiology of Aging, 34, e9-e18.
    • (2013) Neurobiology of Aging , vol.34
    • Meda, S.A.1    Koran, M.E.2    Pryweller, J.R.3    Vega, J.N.4    Thornton-Wells, T.A.5
  • 27
    • 84866077130 scopus 로고    scopus 로고
    • Serum ceramides increase the risk of Alzheimer disease The Women's Health and Aging Study II
    • Mielke, M. M., Bandaru, V. V. R., Haughey, N. J., Xia, J., Fried, L. P., Yasar, S. et al. (2012). Serum ceramides increase the risk of Alzheimer disease The Women's Health and Aging Study II. Neurology, 79, 633-641.
    • (2012) Neurology , vol.79 , pp. 633-641
    • Mielke, M.M.1    Bandaru, V.V.R.2    Haughey, N.J.3    Xia, J.4    Fried, L.P.5    Yasar, S.6
  • 28
    • 66549127860 scopus 로고    scopus 로고
    • Episodic memory loss is related to hippocampal-mediated beta-amyloid deposition in elderly subjects
    • Mormino, E. C., Kluth, J. T., Madison, C. M., Rabinovici, G. D., Baker, S. L., Miller, B. L. et al. (2009). Episodic memory loss is related to hippocampal-mediated beta-amyloid deposition in elderly subjects. Brain, 132, 1310-1323.
    • (2009) Brain , vol.132 , pp. 1310-1323
    • Mormino, E.C.1    Kluth, J.T.2    Madison, C.M.3    Rabinovici, G.D.4    Baker, S.L.5    Miller, B.L.6
  • 29
    • 77649314191 scopus 로고    scopus 로고
    • APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging
    • Morris, J. C., Roe, C. M., Xiong, C., Fagan, A. M., Goate, A. M., Holtzman, D. M. et al. (2010). APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging. Annals of Neurology, 67, 122-131.
    • (2010) Annals of Neurology , vol.67 , pp. 122-131
    • Morris, J.C.1    Roe, C.M.2    Xiong, C.3    Fagan, A.M.4    Goate, A.M.5    Holtzman, D.M.6
  • 30
    • 79959588593 scopus 로고    scopus 로고
    • Increased dopaminergic cells and protein aggregates in the olfactory bulb of patients with neurodegenerative disorders
    • Mundiñano, I. C., Caballero, M. C., Ordóñez, C., Hernandez, M., DiCaudo, C., Marcilla, I. et al. (2011). Increased dopaminergic cells and protein aggregates in the olfactory bulb of patients with neurodegenerative disorders. Acta neuropathologica, 122, 61-74.
    • (2011) Acta neuropathologica , vol.122 , pp. 61-74
    • Mundiñano, I.C.1    Caballero, M.C.2    Ordóñez, C.3    Hernandez, M.4    DiCaudo, C.5    Marcilla, I.6
  • 33
    • 84861414424 scopus 로고    scopus 로고
    • Within-subject template estimation for unbiased longitudinal image analysis
    • Reuter, M., Schmansky, N. J., Rosas, H. D., & Fischl, B. (2012). Within-subject template estimation for unbiased longitudinal image analysis. Neuroimage.
    • (2012) Neuroimage.
    • Reuter, M.1    Schmansky, N.J.2    Rosas, H.D.3    Fischl, B.4
  • 34
    • 10044250982 scopus 로고    scopus 로고
    • Astroglial expression of ceramide in Alzheimer's disease brains: a role during neuronal apoptosis
    • Satoi, H., Tomimoto, H., Ohtani, R., Kitano, T., Kondo, T., Watanabe, M. et al. (2005). Astroglial expression of ceramide in Alzheimer's disease brains: a role during neuronal apoptosis. Neuroscience, 130, 657-666.
    • (2005) Neuroscience , vol.130 , pp. 657-666
    • Satoi, H.1    Tomimoto, H.2    Ohtani, R.3    Kitano, T.4    Kondo, T.5    Watanabe, M.6
  • 36
    • 78650906323 scopus 로고    scopus 로고
    • Increased brain atrophy rates in cognitively normal older adults with low cerebrospinal fluid Abeta42
    • Schott, J. M., Bartlett, J. W., Fox, N. C., & Barnes, J. (2010). Increased brain atrophy rates in cognitively normal older adults with low cerebrospinal fluid Abeta42. Annals of Neurology, 68, 825-834.
    • (2010) Annals of Neurology , vol.68 , pp. 825-834
    • Schott, J.M.1    Bartlett, J.W.2    Fox, N.C.3    Barnes, J.4
  • 38
    • 31744435871 scopus 로고    scopus 로고
    • Joint analysis is more efficent than replication-based analysis for two-stage genome-wide association studies
    • Skol, A., Scott, L., Abecasis, G, Boehnke, M. (2006). Joint analysis is more efficent than replication-based analysis for two-stage genome-wide association studies. Nature Genetics 38, 209-213.
    • (2006) Nature Genetics , vol.38 , pp. 209-213
    • Skol, A.1    Scott, L.2    Abecasis, G.3    Boehnke, M.4
  • 40
    • 56349119351 scopus 로고    scopus 로고
    • Linking Abeta and tau in late-onset Alzheimer's disease: a dual pathway hypothesis
    • Small, S. A. & Duff, K. (2008). Linking Abeta and tau in late-onset Alzheimer's disease: a dual pathway hypothesis. Neuron, 60, 534-542.
    • (2008) Neuron , vol.60 , pp. 534-542
    • Small, S.A.1    Duff, K.2
  • 41
    • 0037465449 scopus 로고    scopus 로고
    • CSF Abeta 42 levels correlate with amyloid-neuropathology in a population-based autopsy study
    • Strozyk, D., Blennow, K., White, L., & Launer, L. (2003). CSF Abeta 42 levels correlate with amyloid-neuropathology in a population-based autopsy study. Neurology, 60(4), 656-656.
    • (2003) Neurology , vol.60 , Issue.4 , pp. 656-656
    • Strozyk, D.1    Blennow, K.2    White, L.3    Launer, L.4
  • 43
    • 77954030909 scopus 로고    scopus 로고
    • Relations between brain tissue loss, CSF biomarkers and the ApoE genetic profile: A longitudinal MRI study
    • Tosun, D., Schuff, N., Truran-Sacrey, D., Shaw, L. M., Trojanowski, J. Q., Aisen, P. et al. (2010). Relations between brain tissue loss, CSF biomarkers and the ApoE genetic profile: A longitudinal MRI study. Neurobiology of Aging, 31, 1340.
    • (2010) Neurobiology of Aging , vol.31 , pp. 1340
    • Tosun, D.1    Schuff, N.2    Truran-Sacrey, D.3    Shaw, L.M.4    Trojanowski, J.Q.5    Aisen, P.6
  • 44
    • 68249090572 scopus 로고    scopus 로고
    • MRI and CSF biomarkers in normal, MCI, and AD subjects Diagnostic discrimination and cognitive correlations
    • Vemuri, P., Wiste, H. J., Weigand, S. D., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W. et al. (2009a). MRI and CSF biomarkers in normal, MCI, and AD subjects Diagnostic discrimination and cognitive correlations. Neurology, 73, 287-293.
    • (2009) Neurology , vol.73 , pp. 287-293
    • Vemuri, P.1    Wiste, H.J.2    Weigand, S.D.3    Shaw, L.M.4    Trojanowski, J.Q.5    Weiner, M.W.6
  • 45
    • 68249111164 scopus 로고    scopus 로고
    • MRI and CSF biomarkers in normal, MCI, and AD subjects Predicting future clinical change
    • Vemuri, P., Wiste, H. J., Weigand, S. D., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W. et al. (2009b). MRI and CSF biomarkers in normal, MCI, and AD subjects Predicting future clinical change. Neurology, 73, 294-301.
    • (2009) Neurology , vol.73 , pp. 294-301
    • Vemuri, P.1    Wiste, H.J.2    Weigand, S.D.3    Shaw, L.M.4    Trojanowski, J.Q.5    Weiner, M.W.6
  • 46
    • 84858779229 scopus 로고    scopus 로고
    • HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants
    • Ward, L. D. & Kellis, M. (2012). HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants. Nucleic Acids Research, 40, D930-D934.
    • (2012) Nucleic Acids Research , vol.40
    • Ward, L.D.1    Kellis, M.2
  • 47
    • 84870481457 scopus 로고    scopus 로고
    • Mitochondrial ferritin attenuates β-amyloid-induced neurotoxicity: reduction in oxidative damage through the Erk/P38 mitogen-activated protein kinase pathways
    • Wu, W., Zhao, Y., Shi, Z., Chang, S., Nie, G., Duan, X., et al. (2013). Mitochondrial ferritin attenuates β-amyloid-induced neurotoxicity: reduction in oxidative damage through the Erk/P38 mitogen-activated protein kinase pathways. Antioxidants & Redox Signlaing, 18(2), 158-169.
    • (2013) Antioxidants & Redox Signlaing , vol.18 , Issue.2 , pp. 158-169
    • Wu, W.1    Zhao, Y.2    Shi, Z.3    Chang, S.4    Nie, G.5    Duan, X.6


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