메뉴 건너뛰기




Volumn 111, Issue 2, 2014, Pages 309-317

The pro-apoptotic role of autophagy in breast cancer

Author keywords

autophagy; growth inhibition; LC3B expression; natural compound and breast cancer; tissue microarray

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; SMALL INTERFERING RNA;

EID: 84904576380     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2014.203     Document Type: Article
Times cited : (30)

References (51)
  • 1
    • 33847026354 scopus 로고    scopus 로고
    • Autophagy delays apoptotic death in breast cancer cells following DNA damage
    • Abedin MJ, Wang D, McDonnell MA, Lehmann U, Kelekar A (2007) Autophagy delays apoptotic death in breast cancer cells following DNA damage. Cell Death Differ 14(3): 500-510.
    • (2007) Cell Death Differ , vol.14 , Issue.3 , pp. 500-510
    • Abedin, M.J.1    Wang, D.2    McDonnell, M.A.3    Lehmann, U.4    Kelekar, A.5
  • 2
    • 84869390181 scopus 로고    scopus 로고
    • Chemopreventive effects of pterostilbene on urethane-induced lung carcinogenesis in mice via the inhibition of EGFR-mediated pathways and the induction of apoptosis and autophagy
    • Chen RJ, Tsai SJ, Ho CT, Pan MH, Ho YS, Wu CH, Wang YJ (2012) Chemopreventive effects of pterostilbene on urethane-induced lung carcinogenesis in mice via the inhibition of EGFR-mediated pathways and the induction of apoptosis and autophagy. J Agric Food Chem 60(46): 11533-11541.
    • (2012) J Agric Food Chem , vol.60 , Issue.46 , pp. 11533-11541
    • Chen, R.J.1    Tsai, S.J.2    Ho, C.T.3    Pan, M.H.4    Ho, Y.S.5    Wu, C.H.6    Wang, Y.J.7
  • 3
    • 84902535394 scopus 로고    scopus 로고
    • Reactive oxygen species generation inhibits epithelial-mesenchymal transition and promotes growth arrest in prostate cancer cells
    • e-pub ahead of print 8 March 2013 doi:10.1002/mc.22014
    • Das TP, Suman S, Damodaran C (2013) Reactive oxygen species generation inhibits epithelial-mesenchymal transition and promotes growth arrest in prostate cancer cells. Mol Carcinog; e-pub ahead of print 8 March 2013; doi:10.1002/mc.22014.
    • (2013) Mol Carcinog
    • Das, T.P.1    Suman, S.2    Damodaran, C.3
  • 5
    • 62949091373 scopus 로고    scopus 로고
    • Autophagy: A lysosomal degradation pathway with a central role in health and disease
    • Eskelinen EL, Saftig P (2009) Autophagy: a lysosomal degradation pathway with a central role in health and disease. Biochim Biophys Acta 1793(4): 664-673.
    • (2009) Biochim Biophys Acta , vol.1793 , Issue.4 , pp. 664-673
    • Eskelinen, E.L.1    Saftig, P.2
  • 6
    • 77951911179 scopus 로고    scopus 로고
    • Regulation of autophagy in mammals and its interplay with apoptosis
    • Fimia GM, Piacentini M (2010) Regulation of autophagy in mammals and its interplay with apoptosis. Cell Mol Life Sci 67(10): 1581-1588.
    • (2010) Cell Mol Life Sci , vol.67 , Issue.10 , pp. 1581-1588
    • Fimia, G.M.1    Piacentini, M.2
  • 7
    • 39049194057 scopus 로고    scopus 로고
    • The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function
    • Furuya N, Yu J, Byfield M, Pattingre S, Levine B (2005) The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function. Autophagy 1(1): 46-52.
    • (2005) Autophagy , vol.1 , Issue.1 , pp. 46-52
    • Furuya, N.1    Yu, J.2    Byfield, M.3    Pattingre, S.4    Levine, B.5
  • 8
    • 0026709013 scopus 로고
    • Detection of frequent allelic loss on proximal chromosome 17q in sporadic breast carcinoma using microsatellite length polymorphisms
    • Futreal PA, Soderkvist P, Marks JR, Iglehart JD, Cochran C, Barrett JC, Wiseman RW (1992) Detection of frequent allelic loss on proximal chromosome 17q in sporadic breast carcinoma using microsatellite length polymorphisms. Cancer Res 52(9): 2624-2627.
    • (1992) Cancer Res , vol.52 , Issue.9 , pp. 2624-2627
    • Futreal, P.A.1    Soderkvist, P.2    Marks, J.R.3    Iglehart, J.D.4    Cochran, C.5    Barrett, J.C.6    Wiseman, R.W.7
  • 10
    • 43149090064 scopus 로고    scopus 로고
    • FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells
    • Hara T, Takamura A, Kishi C, Iemura S, Natsume T, Guan JL, Mizushima N (2008) FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells. J Cell Biol 181(3): 497-510.
    • (2008) J Cell Biol , vol.181 , Issue.3 , pp. 497-510
    • Hara, T.1    Takamura, A.2    Kishi, C.3    Iemura, S.4    Natsume, T.5    Guan, J.L.6    Mizushima, N.7
  • 11
    • 42649122953 scopus 로고    scopus 로고
    • Blocking on the CXCR4/mTOR signalling pathway induces the anti-metastatic properties and autophagic cell death in peritoneal disseminated gastric cancer cells
    • Hashimoto I, Koizumi K, Tatematsu M, Minami T, Cho S, Takeno N, Nakashima A, Sakurai H, Saito S, Tsukada K, Saiki I (2008) Blocking on the CXCR4/mTOR signalling pathway induces the anti-metastatic properties and autophagic cell death in peritoneal disseminated gastric cancer cells. Eur J Cancer 44(7): 1022-1029.
    • (2008) Eur J Cancer , vol.44 , Issue.7 , pp. 1022-1029
    • Hashimoto, I.1    Koizumi, K.2    Tatematsu, M.3    Minami, T.4    Cho, S.5    Takeno, N.6    Nakashima, A.7    Sakurai, H.8    Saito, S.9    Tsukada, K.10    Saiki, I.11
  • 15
    • 1842865745 scopus 로고    scopus 로고
    • Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells
    • Kanzawa T, Germano IM, Komata T, Ito H, Kondo Y, Kondo S (2004) Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells. Cell Death Differ 11(4): 448-457.
    • (2004) Cell Death Differ , vol.11 , Issue.4 , pp. 448-457
    • Kanzawa, T.1    Germano, I.M.2    Komata, T.3    Ito, H.4    Kondo, Y.5    Kondo, S.6
  • 17
    • 48249090416 scopus 로고    scopus 로고
    • Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer
    • Kim KW, Hwang M, Moretti L, Jaboin JJ, Cha YI, Lu B (2008) Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer. Autophagy 4(5): 659-668.
    • (2008) Autophagy , vol.4 , Issue.5 , pp. 659-668
    • Kim, K.W.1    Hwang, M.2    Moretti, L.3    Jaboin, J.J.4    Cha, Y.I.5    Lu, B.6
  • 18
    • 0034537290 scopus 로고    scopus 로고
    • Autophagy as a regulated pathway of cellular degradation
    • Klionsky DJ, Emr SD (2000) Autophagy as a regulated pathway of cellular degradation. Science 290(5497): 1717-1721.
    • (2000) Science , vol.290 , Issue.5497 , pp. 1717-1721
    • Klionsky, D.J.1    Emr, S.D.2
  • 19
    • 33645944960 scopus 로고    scopus 로고
    • Autophagy and cancer therapy
    • Kondo Y, Kondo S (2006) Autophagy and cancer therapy. Autophagy 2(2): 85-90.
    • (2006) Autophagy , vol.2 , Issue.2 , pp. 85-90
    • Kondo, Y.1    Kondo, S.2
  • 20
    • 28544435485 scopus 로고    scopus 로고
    • Lysosomes and autophagy in cell death control
    • Kroemer G, Jaattela M (2005) Lysosomes and autophagy in cell death control. Nat Rev Cancer 5(11): 886-897.
    • (2005) Nat Rev Cancer , vol.5 , Issue.11 , pp. 886-897
    • Kroemer, G.1    Jaattela, M.2
  • 21
    • 56749170677 scopus 로고    scopus 로고
    • Autophagic cell death: The story of a misnomer
    • Kroemer G, Levine B (2008) Autophagic cell death: the story of a misnomer. Nat Rev Mol Cell Biol 9(12): 1004-1010.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , Issue.12 , pp. 1004-1010
    • Kroemer, G.1    Levine, B.2
  • 23
    • 77953289524 scopus 로고    scopus 로고
    • Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model
    • Li J, Hou N, Faried A, Tsutsumi S, Kuwano H (2010) Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model. Eur J Cancer 46(10): 1900-1909.
    • (2010) Eur J Cancer , vol.46 , Issue.10 , pp. 1900-1909
    • Li, J.1    Hou, N.2    Faried, A.3    Tsutsumi, S.4    Kuwano, H.5
  • 25
    • 12944303650 scopus 로고    scopus 로고
    • Growth factor regulation of autophagy and cell survival in the absence of apoptosis
    • Lum JJ, Bauer DE, Kong M, Harris MH, Li C, Lindsten T, Thompson CB (2005) Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell 120(2): 237-248.
    • (2005) Cell , vol.120 , Issue.2 , pp. 237-248
    • Lum, J.J.1    Bauer, D.E.2    Kong, M.3    Harris, M.H.4    Li, C.5    Lindsten, T.6    Thompson, C.B.7
  • 26
    • 34548188741 scopus 로고    scopus 로고
    • Self-eating and selfkilling: Crosstalk between autophagy and apoptosis
    • Maiuri MC, Zalckvar E, Kimchi A, Kroemer G (2007) Self-eating and selfkilling: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 8(9): 741-752.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , Issue.9 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 29
    • 35848967804 scopus 로고    scopus 로고
    • How to interpret LC3 immunoblotting
    • Mizushima N, Yoshimori T (2007) How to interpret LC3 immunoblotting. Autophagy 3(6): 542-545.
    • (2007) Autophagy , vol.3 , Issue.6 , pp. 542-545
    • Mizushima, N.1    Yoshimori, T.2
  • 30
    • 46749155554 scopus 로고    scopus 로고
    • Survivin and caspase-3 expression in breast cancer: Correlation with prognostic parameters, proliferation, angiogenesis, and outcome
    • Nassar A, Lawson D, Cotsonis G, Cohen C (2008) Survivin and caspase-3 expression in breast cancer: correlation with prognostic parameters, proliferation, angiogenesis, and outcome. Appl Immunohistochem Mol Morphol 16(2): 113-120.
    • (2008) Appl Immunohistochem Mol Morphol , vol.16 , Issue.2 , pp. 113-120
    • Nassar, A.1    Lawson, D.2    Cotsonis, G.3    Cohen, C.4
  • 34
    • 33646096970 scopus 로고    scopus 로고
    • Effects of natural prenylated flavones in the phenotypical ER (\+) MCF-7 and ER (-) MDA-MB-231 human breast cancer cells
    • Pedro M, Lourenco CF, Cidade H, Kijjoa A, Pinto M, Nascimento MS (2006) Effects of natural prenylated flavones in the phenotypical ER (\+) MCF-7 and ER (-) MDA-MB-231 human breast cancer cells. Toxicol Lett 164(1): 24-36.
    • (2006) Toxicol Lett , vol.164 , Issue.1 , pp. 24-36
    • Pedro, M.1    Lourenco, C.F.2    Cidade, H.3    Kijjoa, A.4    Pinto, M.5    Nascimento, M.S.6
  • 40
    • 84859360525 scopus 로고    scopus 로고
    • Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy
    • ShiWY, Xiao D, Wang L, Dong LH, Yan ZX, Shen ZX, Chen SJ, Chen Y, ZhaoWL (2012) Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy. Cell Death Dis 3: e275.
    • (2012) Cell Death Dis , vol.3
    • Shi, W.Y.1    Xiao, D.2    Wang, L.3    Dong, L.H.4    Yan, Z.X.5    Shen, Z.X.6    Chen, S.J.7    Chen, Y.8    Zhao, W.L.9
  • 42
    • 84887849044 scopus 로고    scopus 로고
    • Silencing NOTCH signaling causes growth arrest in both breast cancer stem cells and breast cancer cells
    • Suman S, Das TP, Damodaran C (2013a) Silencing NOTCH signaling causes growth arrest in both breast cancer stem cells and breast cancer cells. Br J Cancer 109(10): 2587-2596.
    • (2013) Br J Cancer , vol.109 , Issue.10 , pp. 2587-2596
    • Suman, S.1    Das, T.P.2    Damodaran, C.3
  • 43
    • 84894445272 scopus 로고    scopus 로고
    • Activation of AKT signaling promotes epithelialmesenchymal transition and tumor growth in colorectal cancer cells
    • Suman S, Kurisetty V, Das TP, Vadodkar A, Ramos G, Lakshmanaswamy R, Damodaran C (2013b) Activation of AKT signaling promotes epithelialmesenchymal transition and tumor growth in colorectal cancer cells. Mol Carcinog 53(Suppl 1): E151-E160.
    • (2013) Mol Carcinog , vol.53 , Issue.SUPPL. 1
    • Suman, S.1    Kurisetty, V.2    Das, T.P.3    Vadodkar, A.4    Ramos, G.5    Lakshmanaswamy, R.6    Damodaran, C.7
  • 44
    • 4344624322 scopus 로고    scopus 로고
    • LC3 conjugation system in mammalian autophagy
    • Tanida I, Ueno T, Kominami E (2004) LC3 conjugation system in mammalian autophagy. Int J Biochem Cell Biol 36(12): 2503-2518.
    • (2004) Int J Biochem Cell Biol , vol.36 , Issue.12 , pp. 2503-2518
    • Tanida, I.1    Ueno, T.2    Kominami, E.3
  • 45
    • 40549085336 scopus 로고    scopus 로고
    • Resveratrol-induced apoptosis depends on the lipid kinase activity of Vps34 and on the formation of autophagolysosomes
    • Trincheri NF, Follo C, Nicotra G, Peracchio C, Castino R, Isidoro C (2008) Resveratrol-induced apoptosis depends on the lipid kinase activity of Vps34 and on the formation of autophagolysosomes. Carcinogenesis 29(2): 381-389.
    • (2008) Carcinogenesis , vol.29 , Issue.2 , pp. 381-389
    • Trincheri, N.F.1    Follo, C.2    Nicotra, G.3    Peracchio, C.4    Castino, R.5    Isidoro, C.6
  • 46
    • 44949237240 scopus 로고    scopus 로고
    • JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy
    • Wei Y, Pattingre S, Sinha S, Bassik M, Levine B (2008) JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy. Mol Cell 30(6): 678-688.
    • (2008) Mol Cell , vol.30 , Issue.6 , pp. 678-688
    • Wei, Y.1    Pattingre, S.2    Sinha, S.3    Bassik, M.4    Levine, B.5
  • 47
    • 84862974996 scopus 로고    scopus 로고
    • Dietary flavonoid fisetin targets caspase-3-deficient human breast cancer MCF-7 cells by induction of caspase-7-associated apoptosis and inhibition of autophagy
    • Yang PM, Tseng HH, Peng CW, Chen WS, Chiu SJ (2012) Dietary flavonoid fisetin targets caspase-3-deficient human breast cancer MCF-7 cells by induction of caspase-7-associated apoptosis and inhibition of autophagy. Int J Oncol 40(2): 469-478.
    • (2012) Int J Oncol , vol.40 , Issue.2 , pp. 469-478
    • Yang, P.M.1    Tseng, H.H.2    Peng, C.W.3    Chen, W.S.4    Chiu, S.J.5
  • 48
    • 34548572349 scopus 로고    scopus 로고
    • Caspase expression profile and functional activity in a panel of breast cancer cell lines
    • Yang S, Liu J, Thor AD, Yang X (2007) Caspase expression profile and functional activity in a panel of breast cancer cell lines. Oncol Rep 17(5): 1229-1235.
    • (2007) Oncol Rep , vol.17 , Issue.5 , pp. 1229-1235
    • Yang, S.1    Liu, J.2    Thor, A.D.3    Yang, X.4
  • 49
    • 80052697287 scopus 로고    scopus 로고
    • The role of autophagy in cancer: Therapeutic implications
    • Yang ZJ, Chee CE, Huang S, Sinicrope FA (2011) The role of autophagy in cancer: therapeutic implications. Mol Cancer Ther 10(9): 1533-1541.
    • (2011) Mol Cancer Ther , vol.10 , Issue.9 , pp. 1533-1541
    • Yang, Z.J.1    Chee, C.E.2    Huang, S.3    Sinicrope, F.A.4
  • 50
    • 42049095495 scopus 로고    scopus 로고
    • Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy
    • Zeng X, Kinsella TJ (2008) Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy. Cancer Res 68(7): 2384-2390.
    • (2008) Cancer Res , vol.68 , Issue.7 , pp. 2384-2390
    • Zeng, X.1    Kinsella, T.J.2
  • 51
    • 78751655392 scopus 로고    scopus 로고
    • Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis
    • Zhou F, Yang Y, Xing D (2011) Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis. FEBS J 278(3): 403-413.
    • (2011) FEBS J , vol.278 , Issue.3 , pp. 403-413
    • Zhou, F.1    Yang, Y.2    Xing, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.