A functional variant in APOA5/A4/C3/A1 gene cluster contributes to elevated triglycerides and severity of cad by interfering with MicroRNA 3201 binding efficiency

Journal of the American College of Cardiology

Volumn 64, Issue 3, 2014, Pages 267-277

  Cui, Guanglin ^a   Li, Zongzhe ^a   Li, Rui ^a   Huang, Jin ^a   Wang, Haoran ^a   Zhang, Lina ^a   Ding, Hu ^a   Wang, Dao Wen ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

APOA5 A4 C3 A1 gene cluster; coronary artery disease; genetics; lipids

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN A4; APOLIPOPROTEIN A5; APOLIPOPROTEIN C3; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MICRORNA; MICRORNA 3201; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ADULT; APOA1 GENE; APOA4 GENE; APOA5 GENE; APOC3 GENE; ARTICLE; CHINESE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORONARY RISK; DISEASE SEVERITY; ETHNICITY; FEMALE; GENE CLUSTER; GENE DOSAGE; GENE FREQUENCY; GENE FUNCTION; GENE IDENTIFICATION; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENSINI SCORE; HIGH RISK POPULATION; HUMAN; HYPERTRIGLYCERIDEMIA; MAJOR CLINICAL STUDY; MALE; METABOLIC REGULATION; MOLECULAR PATHOLOGY; PRIORITY JOURNAL; RISK ASSESSMENT; RNA BINDING; RNA INTERFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM; TRIACYLGLYCEROL BLOOD LEVEL;

APOA5/A4/C3/A1 GENE CLUSTER; CORONARY ARTERY DISEASE; GENETICS; LIPIDS;

ADULT; AGED; AGED, 80 AND OVER; APOLIPOPROTEIN A-I; APOLIPOPROTEIN C-III; APOLIPOPROTEINS A; ASIAN CONTINENTAL ANCESTRY GROUP; COHORT STUDIES; CORONARY ARTERY DISEASE; FEMALE; GENETIC VARIATION; HUMANS; MALE; MICRORNAS; MIDDLE AGED; MULTIGENE FAMILY; PROTEIN BINDING; SEVERITY OF ILLNESS INDEX; TRIGLYCERIDES; YOUNG ADULT;

EID: 84904565986     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2014.03.050     Document Type: Article

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