Three TNFR-binding domains of PGRN act independently in inhibition of TNF-alpha binding and activity

Frontiers in Bioscience - Landmark

Volumn 19, Issue 7, 2014, Pages 1176-1185

  Tian, Qingyun ^a   Zhao, Yunpeng ^a   Mundra, Jyoti Joshi ^a   Gonzalez Gugel, Elena ^a   Jian, Jinlong ^a   Uddin, Sardar M Z ^a   Liu, Chuan Ju ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Activity; Atsttrin; Inflammation; Inhibition; PGRN; TNF; TNF alpha; TNFR

Indexed keywords

GRN PROTEIN, HUMAN; INTERCELLULAR ADHESION MOLECULE 1; PROTEIN BINDING; RECOMBINANT PROTEIN; SIGNAL PEPTIDE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL; ARTHRITIS, EXPERIMENTAL; BINDING SITE; C57BL MOUSE; CELL CULTURE; CELL LINE; CELL MEMBRANE; DBA MOUSE; DRUG EFFECTS; GENE EXPRESSION; GENETICS; HEK293 CELL LINE; HUMAN; MACROPHAGE; MALE; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; TUMOR CELL LINE; TWO HYBRID SYSTEM;

ANIMALS; ARTHRITIS, EXPERIMENTAL; BINDING SITES; CELL LINE; CELL LINE, TUMOR; CELL MEMBRANE; CELLS, CULTURED; GENE EXPRESSION; HEK293 CELLS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MACROPHAGES; MALE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; PROTEIN BINDING; RECEPTORS, TUMOR NECROSIS FACTOR; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR NECROSIS FACTOR-ALPHA; TWO-HYBRID SYSTEM TECHNIQUES; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84904562987     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/4274     Document Type: Article

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