Predicting diffusive transport of cationic liposomes in 3-dimensional tumor spheroids

Journal of Controlled Release

Volumn 192, Issue , 2014, Pages 10-18

  Wientjes, Michael G ^a   Yeung, Bertrand Z ^a,b   Lu, Ze ^a   Wientjes, M Guillaume ^a   Au, Jessie L S ^a,b  

^a Optimum Energy LLC   (United States)

^b UNIVERSITY OF OKLAHOMA   (United States)

Author keywords

3 Dimensional tumors; Cationic liposomes; Diffusive transport; Fusogenic lipid; Nanoparticle; Spatiokinetics

Indexed keywords

DIFFUSION; MONOLAYERS; NANOPARTICLES; TUMORS;

3-DIMENSIONAL; CATIONIC LIPOSOMES; CONCENTRATION-DEPTH PROFILE; DIFFUSIVE TRANSPORT; EFFECTIVE DIFFUSIVITIES; EXTRACELLULAR CONCENTRATION; SPATIOKINETICS; SUBCELLULAR COMPARTMENTS;

LIPOSOMES;

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; 1,2 DIOLEOYL SN GLYCERO 3 PHOSPHOETHANOLAMINE; LIPID; LIPOSOME; POLYSTYRENE; UNCLASSIFIED DRUG; 1,2-DIELAIDOYLPHOSPHATIDYLETHANOLAMINE; 1,2-DIOLEOYLOXY-3-(TRIMETHYLAMMONIUM)PROPANE; MONOUNSATURATED FATTY ACID; PHOSPHATIDYLETHANOLAMINE; QUATERNARY AMMONIUM DERIVATIVE;

ARTICLE; BINDING SITE; CELLULAR PARAMETERS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DIFFUSION; DRUG RETENTION; DRUG TRANSPORT; DRUG UPTAKE; HUMAN; HUMAN CELL; LIPOSOMAL DELIVERY; MONOLAYER CULTURE; PARTICLE SIZE; PRIORITY JOURNAL; SURFACE CHARGE; TUMOR SPHEROID; ZETA POTENTIAL; CHEMISTRY; COMPUTER SIMULATION; DIFFUSION; METABOLISM; MULTICELLULAR SPHEROID; NEOPLASM; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL CULTURE;

BIOLOGICAL TRANSPORT; COMPUTER SIMULATION; DIFFUSION; FATTY ACIDS, MONOUNSATURATED; HUMANS; LIPOSOMES; NEOPLASMS; PHOSPHATIDYLETHANOLAMINES; QUATERNARY AMMONIUM COMPOUNDS; SPHEROIDS, CELLULAR; TUMOR CELLS, CULTURED;

EID: 84904562016     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.06.050     Document Type: Article

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