Predictive models of diffusive nanoparticle transport in 3-dimensional tumor cell spheroids

AAPS Journal

Volumn 15, Issue 3, 2013, Pages 816-831

  Gao, Yue ^a   Li, Mingguang ^b   Chen, Bin ^a   Shen, Zancong ^a   Guo, Peng ^a   Wientjes, M Guillaume ^a,b   Au, Jessie L S ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b Optimum Energy LLC   (United States)

Author keywords

3 dimensional tumors; computational models; diffusional transport; nanoparticle; solid tumors

Indexed keywords

LIPOSOME; NANOPARTICLE; POLYSTYRENE;

ARTICLE; CELL INTERACTION; CELL SIZE; COMPUTER MODEL; CONTROLLED STUDY; DRUG DIFFUSION; DRUG PROTEIN BINDING; DRUG TRANSPORT; IN VITRO STUDY; INTERNALIZATION; NANOPHARMACEUTICS; PHYSICAL CHEMISTRY; PREDICTION; PROCESS DEVELOPMENT; SURFACE PROPERTY; TRANSMISSION ELECTRON MICROSCOPY; TUMOR SPHEROID;

BIOLOGICAL TRANSPORT; DIFFUSION; FORECASTING; HUMANS; IMAGING, THREE-DIMENSIONAL; MODELS, MOLECULAR; NANOPARTICLES; NEOPLASMS; SPHEROIDS, CELLULAR; TUMOR CELLS, CULTURED;

EID: 84879800181     PISSN: 15507416     EISSN: None     Source Type: Journal    
DOI: 10.1208/s12248-013-9478-2     Document Type: Article

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