Combined vildagliptin and metformin exert better cardioprotection than monotherapy against ischemia-reperfusion injury in obese-insulin resistant rats

PLoS ONE

Volumn 9, Issue 7, 2014, Pages

  Apaijai, Nattayaporn ^a   Chinda, Kroekkiat ^a   Palee, Siripong ^a,c   Chattipakorn, Siriporn ^a,b   Chattipakorn, Nipon ^a,b  

^a Faculty of Medicine Chiang Mai University   (Thailand)

^b CHIANG MAI UNIVERSITY   (Thailand)

^c MAE FAH LUANG UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CHOLESTEROL; CONNEXIN 43; GLUCOSE; INSULIN; METFORMIN; PHOSPHOPROTEIN; PROTEIN BAX; PROTEIN BCL 2; TRIACYLGLYCEROL; VILDAGLIPTIN; ADAMANTANE; CARDIOTONIC AGENT; DIPEPTIDYL PEPTIDASE IV INHIBITOR; NITRILE; PYRROLIDINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARRHYTHMIA SCORE; ARTERY LIGATION; ARTICLE; CALCIUM MOBILIZATION; CARDIOVASCULAR MORTALITY; CELL FUNCTION; CONTROLLED STUDY; DIETARY INTAKE; FOOD INTAKE; GLUCOSE BLOOD LEVEL; HEART ARRHYTHMIA; HEART INFARCTION SIZE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HEART RATE VARIABILITY; INSULIN RESISTANCE; LIPID DIET; MALE; METABOLIC PARAMETERS; MITOCHONDRION; MONOTHERAPY; NONHUMAN; OBESITY; RAT; REPERFUSION INJURY; SCORING SYSTEM; ANALOGS AND DERIVATIVES; ANIMAL; ARRHYTHMIAS, CARDIAC; COMPARATIVE STUDY; COMPLICATION; DRUG EFFECTS; DRUG INTERACTION; HEART RATE; INTRACELLULAR SPACE; METABOLISM; MYOCARDIAL REPERFUSION INJURY; PATHOLOGY; PATHOPHYSIOLOGY; WISTAR RAT;

ADAMANTANE; ANIMALS; ARRHYTHMIAS, CARDIAC; CALCIUM; CARDIOTONIC AGENTS; DIPEPTIDYL-PEPTIDASE IV INHIBITORS; DRUG INTERACTIONS; HEART RATE; INSULIN RESISTANCE; INTRACELLULAR SPACE; MALE; METFORMIN; MITOCHONDRIA; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; NITRILES; OBESITY; PYRROLIDINES; RATS; RATS, WISTAR; VENTRICULAR DYSFUNCTION, LEFT;

EID: 84904540452     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0102374     Document Type: Article

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