Disruption of Aspm causes microcephaly with abnormal neuronal differentiation

Brain and Development

Volumn 36, Issue 8, 2014, Pages 661-669

  Fujimori, Akira ^a   Itoh, Kyoko ^b   Goto, Shoko ^b   Hirakawa, Hirokazu ^a   Wang, Bing ^a   Kokubo, Toshiaki ^a   Kito, Seiji ^a   Tsukamoto, Satoshi ^a   Fushiki, Shinji ^b  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

ASPM; Cortex; Differentiation; Knock out mice; Microcephaly

Indexed keywords

CRE RECOMBINASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SATB2; TRANSCRIPTION FACTOR TBR1; UNCLASSIFIED DRUG; ASPM PROTEIN, MOUSE; CALMODULIN BINDING PROTEIN; NERVE PROTEIN;

ABNORMAL SPINDLE LIKE MICROCEPHALY ASSOCIATED GENE; ADULT; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN DEVELOPMENT; CELL COUNT; CELL PROLIFERATION; CONTROLLED STUDY; CORTICAL THICKNESS (BRAIN); EMBRYO; ENZYME ACTIVITY; EXON; FETUS; GENE; GENE DISRUPTION; GENE EXPRESSION; GENE LOSS; IMMUNOHISTOCHEMISTRY; LOXP SITE; MICROCEPHALY; MORPHOMETRICS; MOUSE; MOUSE MODEL; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NEUROPATHOLOGY; NONHUMAN; SOMATOSENSORY CORTEX; WILD TYPE; ZYGOTE; ANIMAL; CELL DIFFERENTIATION; DISEASE MODEL; GENETICS; KNOCKOUT MOUSE; MALE; METABOLISM; NERVE CELL; PATHOLOGY; TESTIS;

ANIMALS; BRAIN; CALMODULIN-BINDING PROTEINS; CELL DIFFERENTIATION; DISEASE MODELS, ANIMAL; MALE; MICE; MICE, KNOCKOUT; MICROCEPHALY; NERVE TISSUE PROTEINS; NEURONS; TESTIS;

EID: 84904514346     PISSN: 03877604     EISSN: 18727131     Source Type: Journal    
DOI: 10.1016/j.braindev.2013.10.006     Document Type: Article

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