메뉴 건너뛰기




Volumn 34, Issue 7, 2014, Pages 1084-1093

Strain dependence of diet-induced NASH and liver fibrosis in obese mice is linked to diabetes and inflammatory phenotype

Author keywords

Cytokines; Fibrosis; Growth factors; Non alcoholic steatohepatitis; Strain difference

Indexed keywords

ALMS1 PROTEIN, MOUSE; CYTOKINE; DNA BINDING PROTEIN; MATRIX METALLOPROTEINASE; SIGNAL PEPTIDE;

EID: 84904503999     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.12335     Document Type: Article
Times cited : (76)

References (38)
  • 1
    • 84859404868 scopus 로고    scopus 로고
    • Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: Pathophysiology and clinical implications
    • Cusi K. Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: Pathophysiology and clinical implications. Gastroenterology 2012; 142: 711-25.
    • (2012) Gastroenterology , vol.142 , pp. 711-725
    • Cusi, K.1
  • 3
    • 84865545850 scopus 로고    scopus 로고
    • Association between diabetes, family history of diabetes, and risk of nonalcoholic steatohepatitis and fibrosis
    • Loomba R, Abraham M, Unalp A, et al. Association between diabetes, family history of diabetes, and risk of nonalcoholic steatohepatitis and fibrosis. Hepatology 2012; 56: 943-51.
    • (2012) Hepatology , vol.56 , pp. 943-951
    • Loomba, R.1    Abraham, M.2    Unalp, A.3
  • 4
    • 34247384560 scopus 로고    scopus 로고
    • The NAFLD fibrosis score: A noninvasive system that identifies liver fibrosis in patients with NAFLD
    • Angulo P, Hui JM, Marchesini G, et al. The NAFLD fibrosis score: A noninvasive system that identifies liver fibrosis in patients with NAFLD. Hepatology 2007; 45: 846-54.
    • (2007) Hepatology , vol.45 , pp. 846-854
    • Angulo, P.1    Hui, J.M.2    Marchesini, G.3
  • 5
    • 67649306197 scopus 로고    scopus 로고
    • Systematic review of risk factors for fibrosis progression in non-alcoholic steatohepatitis
    • Argo CK, Northup PG, Al-Osaimi AMS, Caldwell SH. Systematic review of risk factors for fibrosis progression in non-alcoholic steatohepatitis. J Hepatol 2009; 51: 371-9.
    • (2009) J Hepatol , vol.51 , pp. 371-379
    • Argo, C.K.1    Northup, P.G.2    Al-Osaimi, A.M.S.3    Caldwell, S.H.4
  • 6
    • 79960438659 scopus 로고    scopus 로고
    • Diabetes is a progression factor for hepatic fibrosis in a high fat fed mouse obesity model of non-alcoholic steatohepatitis
    • Lo L, Mclennan SV, Williams PF, et al. Diabetes is a progression factor for hepatic fibrosis in a high fat fed mouse obesity model of non-alcoholic steatohepatitis. J Hepatol 2011; 55: 435-44.
    • (2011) J Hepatol , vol.55 , pp. 435-444
    • Lo, L.1    Mclennan, S.V.2    Williams, P.F.3
  • 7
    • 56749096610 scopus 로고    scopus 로고
    • Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
    • Romeo S, Kozlitina J, Xing C, et al. Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. Nat Genet 2008; 40: 1461-5.
    • (2008) Nat Genet , vol.40 , pp. 1461-1465
    • Romeo, S.1    Kozlitina, J.2    Xing, C.3
  • 8
    • 77950607738 scopus 로고    scopus 로고
    • Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease
    • Valenti L, Al-Serri A, Daly AK, et al. Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease. Hepatology 2010; 51: 1209-17.
    • (2010) Hepatology , vol.51 , pp. 1209-1217
    • Valenti, L.1    Al-Serri, A.2    Daly, A.K.3
  • 9
    • 78049457761 scopus 로고    scopus 로고
    • Genome-wide association study identifies variants associated with histologic features of nonalcoholic fatty liver disease
    • Chalasani N, Guo X, Loomba R, et al. Genome-wide association study identifies variants associated with histologic features of nonalcoholic fatty liver disease. Gastroenterology 2010; 139: 1567-76.
    • (2010) Gastroenterology , vol.139 , pp. 1567-1576
    • Chalasani, N.1    Guo, X.2    Loomba, R.3
  • 10
    • 0036578890 scopus 로고    scopus 로고
    • Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alstrom syndrome
    • Collin GB, Marshall JD, Ikeda A, et al. Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alstrom syndrome. Nat Genet 2002; 31: 74-8.
    • (2002) Nat Genet , vol.31 , pp. 74-78
    • Collin, G.B.1    Marshall, J.D.2    Ikeda, A.3
  • 12
    • 33745651353 scopus 로고    scopus 로고
    • Fat Aussie-A new Alström syndrome mouse showing a critical role for ALMS1 in obesity, diabetes, and spermatogenesis
    • Arsov T, Silva DG, O'bryan MK, et al. Fat Aussie-A new Alström syndrome mouse showing a critical role for ALMS1 in obesity, diabetes, and spermatogenesis. Mol Endocrinol 2006; 20: 1610-22.
    • (2006) Mol Endocrinol , vol.20 , pp. 1610-1622
    • Arsov, T.1    Silva, D.G.2    O'bryan, M.K.3
  • 13
    • 84870761696 scopus 로고    scopus 로고
    • A truncating mutation of Alms1 reduces the number of hypothalamic neuronal cilia in obese mice
    • Heydet D, Chen LX, Larter CZ, et al. A truncating mutation of Alms1 reduces the number of hypothalamic neuronal cilia in obese mice. Dev Neurobiol 2012; 73: 1-13.
    • (2012) Dev Neurobiol , vol.73 , pp. 1-13
    • Heydet, D.1    Chen, L.X.2    Larter, C.Z.3
  • 14
    • 70349684935 scopus 로고    scopus 로고
    • Roles of adipose restriction and metabolic factors in progression of steatosis to steatohepatitis in obese, diabetic mice
    • Larter CZ, Yeh MM, Van Rooyen DM, et al. Roles of adipose restriction and metabolic factors in progression of steatosis to steatohepatitis in obese, diabetic mice. J Gastroenterol Hepatol 2009; 24: 1658-68.
    • (2009) J Gastroenterol Hepatol , vol.24 , pp. 1658-1668
    • Larter, C.Z.1    Yeh, M.M.2    Van Rooyen, D.M.3
  • 15
    • 80053612479 scopus 로고    scopus 로고
    • Hepatic free cholesterol accumulates in obese, diabetic mice and causes nonalcoholic steatohepatitis
    • Van Rooyen DM, Larter CZ, Haigh WG, et al. Hepatic free cholesterol accumulates in obese, diabetic mice and causes nonalcoholic steatohepatitis. Gastroenterology 2011; 141: 1393-403.
    • (2011) Gastroenterology , vol.141 , pp. 1393-1403
    • Van Rooyen, D.M.1    Larter, C.Z.2    Haigh, W.G.3
  • 16
    • 5644231992 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
    • Ozcan U, Cao Q, Yilmaz E, et al. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 2004; 306: 457-61.
    • (2004) Science , vol.306 , pp. 457-461
    • Ozcan, U.1    Cao, Q.2    Yilmaz, E.3
  • 17
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of a histological scoring system for nonalcoholic fatty liver disease
    • Kleiner DE, Brunt EM, Van Natta M, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 2005; 41: 1313-21.
    • (2005) Hepatology , vol.41 , pp. 1313-1321
    • Kleiner, D.E.1    Brunt, E.M.2    Van Natta, M.3
  • 18
    • 32244446322 scopus 로고    scopus 로고
    • 2-Methoxy-2,4-diphenyl-3(2H)-furanone-labeled gelatin zymography and reverse zymography: A rapid real-time method for quantification of matrix metalloproteinases-2 and -9 and tissue inhibitors of metalloproteinases
    • Min D, Lyons JG, Jia J, Lo L, Mclennan SV. 2-Methoxy-2, 4-diphenyl-3(2H)-furanone-labeled gelatin zymography and reverse zymography: A rapid real-time method for quantification of matrix metalloproteinases-2 and -9 and tissue inhibitors of metalloproteinases. Electrophoresis 2006; 27: 357-64.
    • (2006) Electrophoresis , vol.27 , pp. 357-364
    • Min, D.1    Lyons, J.G.2    Jia, J.3    Lo, L.4    Mclennan, S.V.5
  • 19
    • 0037675000 scopus 로고    scopus 로고
    • In situ localization of gelatinolytic activity in the extracellular matrix of metastases of colon cancer in rat liver using quenched fluorogenic DQ-gelatin
    • Mook OR, Van Overbeek C, Ackema EG, Van Maldegem F, Frederiks WM. In situ localization of gelatinolytic activity in the extracellular matrix of metastases of colon cancer in rat liver using quenched fluorogenic DQ-gelatin. J Histochem Cytochem 2003; 51: 821-9.
    • (2003) J Histochem Cytochem , vol.51 , pp. 821-829
    • Mook, O.R.1    Van Overbeek, C.2    Ackema, E.G.3    Van Maldegem, F.4    Frederiks, W.M.5
  • 20
    • 0028795147 scopus 로고
    • The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily
    • Biswas C, Zhang Y, Decastro R, et al. The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily. Cancer Res 1995; 55: 434-9.
    • (1995) Cancer Res , vol.55 , pp. 434-439
    • Biswas, C.1    Zhang, Y.2    Decastro, R.3
  • 21
    • 84881375574 scopus 로고    scopus 로고
    • Dietary modification dampens liver inflammation and fibrosis in obesity-related fatty liver disease
    • Larter CZ, Yeh MM, Haigh WG, et al. Dietary modification dampens liver inflammation and fibrosis in obesity-related fatty liver disease. Obesity 2013; 21: 1189-99.
    • (2013) Obesity , vol.21 , pp. 1189-1199
    • Larter, C.Z.1    Yeh, M.M.2    Haigh, W.G.3
  • 22
    • 84856414714 scopus 로고    scopus 로고
    • Coordinated improvement in glucose tolerance, liver steatosis and obesity-associated inflammation by cannabinoid 1 receptor antagonism in fat Aussie mice
    • Bell-Anderson KS, Aouad L, Williams H, et al. Coordinated improvement in glucose tolerance, liver steatosis and obesity-associated inflammation by cannabinoid 1 receptor antagonism in fat Aussie mice. Int J Obes 2011; 35: 1539-48.
    • (2011) Int J Obes , vol.35 , pp. 1539-1548
    • Bell-Anderson, K.S.1    Aouad, L.2    Williams, H.3
  • 23
    • 84856139907 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-α agonist, Wy 14,643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis
    • Larter CZ, Yeh MM, Van Rooyen DM, et al. Peroxisome proliferator-activated receptor-α agonist, Wy 14, 643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis. J Gastroenterol Hepatol 2012; 27: 341-50.
    • (2012) J Gastroenterol Hepatol , vol.27 , pp. 341-350
    • Larter, C.Z.1    Yeh, M.M.2    Van Rooyen, D.M.3
  • 24
    • 84879132692 scopus 로고    scopus 로고
    • Pharmacological cholesterol lowering reverses fibrotic NASH in obese, diabetic mice with metabolic syndrome
    • Van Rooyen DM, Gan LT, Yeh MM, et al. Pharmacological cholesterol lowering reverses fibrotic NASH in obese, diabetic mice with metabolic syndrome. J Hepatol 2013; 59: 144-52.
    • (2013) J Hepatol , vol.59 , pp. 144-152
    • Van Rooyen, D.M.1    Gan, L.T.2    Yeh, M.M.3
  • 26
    • 84865742981 scopus 로고    scopus 로고
    • Curcumin protects against thioacetamide-induced hepatic fibrosis by attenuating the inflammatory response and inducing apoptosis of damaged hepatocytes
    • Wang M-E, Chen Y-C, Chen IS, et al. Curcumin protects against thioacetamide-induced hepatic fibrosis by attenuating the inflammatory response and inducing apoptosis of damaged hepatocytes. J Nutri Biochem 2012; 23: 1352-66.
    • (2012) J Nutri Biochem , vol.23 , pp. 1352-1366
    • Wang, M.-E.1    Chen, Y.-C.2    Chen, I.S.3
  • 27
    • 33750499085 scopus 로고    scopus 로고
    • The host's genetic background determines the extent of angiogenesis induced by schistosome egg antigens
    • Van De Vijver KK, Colpaert CG, Jacobs W, et al. The host's genetic background determines the extent of angiogenesis induced by schistosome egg antigens. Acta Trop 2006; 99: 243-51.
    • (2006) Acta Trop , vol.99 , pp. 243-251
    • Van De Vijver, K.K.1    Colpaert, C.G.2    Jacobs, W.3
  • 28
    • 0036892365 scopus 로고    scopus 로고
    • Genome-wide analysis of hepatic fibrosis in inbred mice identifies the susceptibility locus Hfib1 on chromosome 15
    • Hillebrandt S, Goos C, Matern S, Lammert F. Genome-wide analysis of hepatic fibrosis in inbred mice identifies the susceptibility locus Hfib1 on chromosome 15. Gastroenterology 2002; 123: 2041-51.
    • (2002) Gastroenterology , vol.123 , pp. 2041-2051
    • Hillebrandt, S.1    Goos, C.2    Matern, S.3    Lammert, F.4
  • 29
    • 19644394861 scopus 로고    scopus 로고
    • Hepatic triglyceride contents are genetically determined in mice: results of a strain survey
    • Lin X, Yue P, Chen Z, Schonfeld G. Hepatic triglyceride contents are genetically determined in mice: results of a strain survey. Am J Phisiol- Gastro Liv Phisiol 2005; 288: G1179-89.
    • (2005) Am J Phisiol- Gastro Liv Phisiol , vol.288
    • Lin, X.1    Yue, P.2    Chen, Z.3    Schonfeld, G.4
  • 30
    • 0030885185 scopus 로고    scopus 로고
    • Strain-specific differences in mouse hepatic wound healing are mediated by divergent T helper cytokine responses
    • Shi Z, Wakil AE, Rockey DC. Strain-specific differences in mouse hepatic wound healing are mediated by divergent T helper cytokine responses. Proc Natl Acad Sci 1997; 94: 10663-8.
    • (1997) Proc Natl Acad Sci , vol.94 , pp. 10663-10668
    • Shi, Z.1    Wakil, A.E.2    Rockey, D.C.3
  • 31
    • 0032934278 scopus 로고    scopus 로고
    • Monocyte chemotactic protein-1 as a chemoattractant for human hepatic stellate cells
    • Marra F, Romanelli RG, Giannini C, et al. Monocyte chemotactic protein-1 as a chemoattractant for human hepatic stellate cells. Hepatology 1999; 29: 140-8.
    • (1999) Hepatology , vol.29 , pp. 140-148
    • Marra, F.1    Romanelli, R.G.2    Giannini, C.3
  • 32
    • 0034802171 scopus 로고    scopus 로고
    • High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: A potential mechanism involved in progression to fibrosis in nonalcoholic steatohepatitis
    • Paradis V, Perlemuter G, Bonvoust F, et al. High glucose and hyperinsulinemia stimulate connective tissue growth factor expression: A potential mechanism involved in progression to fibrosis in nonalcoholic steatohepatitis. Hepatology 2001; 34: 738-44.
    • (2001) Hepatology , vol.34 , pp. 738-744
    • Paradis, V.1    Perlemuter, G.2    Bonvoust, F.3
  • 33
    • 0042092032 scopus 로고    scopus 로고
    • Connective tissue growth factor (CTGF/CCN2) in hepatic fibrosis
    • Rachfal AW, Brigstock DR. Connective tissue growth factor (CTGF/CCN2) in hepatic fibrosis. Hepatol Res 2003; 26: 1-9.
    • (2003) Hepatol Res , vol.26 , pp. 1-9
    • Rachfal, A.W.1    Brigstock, D.R.2
  • 34
    • 79961010787 scopus 로고    scopus 로고
    • Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice
    • Kodama T, Takehara T, Hikita H, et al. Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice. J Clin Invest 2011; 121: 3343-56.
    • (2011) J Clin Invest , vol.121 , pp. 3343-3356
    • Kodama, T.1    Takehara, T.2    Hikita, H.3
  • 35
    • 0036281460 scopus 로고    scopus 로고
    • Effects and regulation of connective tissue growth factor on hepatic stellate cells
    • Paradis V, Dargere D, Bonvoust F, et al. Effects and regulation of connective tissue growth factor on hepatic stellate cells. Lab Invest 2002; 82: 767-74.
    • (2002) Lab Invest , vol.82 , pp. 767-774
    • Paradis, V.1    Dargere, D.2    Bonvoust, F.3
  • 36
    • 41149162565 scopus 로고    scopus 로고
    • Novel transcription-factor-like function of human matrix metalloproteinase 3 regulating the CTGF/CCN2 gene
    • Eguchi T, Kubota S, Kawata K, et al. Novel transcription-factor-like function of human matrix metalloproteinase 3 regulating the CTGF/CCN2 gene. Mol Cell Biol 2008; 28: 2391-413.
    • (2008) Mol Cell Biol , vol.28 , pp. 2391-2413
    • Eguchi, T.1    Kubota, S.2    Kawata, K.3
  • 37
    • 34848865661 scopus 로고    scopus 로고
    • Differential effects of TGF-β on connective tissue growth factor (CTGF/CCN2) expression in hepatic stellate cells and hepatocytes
    • Gressner OA, Lahme B, Demirci I, Gressner AM, Weiskirchen R. Differential effects of TGF-β on connective tissue growth factor (CTGF/CCN2) expression in hepatic stellate cells and hepatocytes. J Hepatol 2007; 47: 699-710.
    • (2007) J Hepatol , vol.47 , pp. 699-710
    • Gressner, O.A.1    Lahme, B.2    Demirci, I.3    Gressner, A.M.4    Weiskirchen, R.5
  • 38
    • 79952361224 scopus 로고    scopus 로고
    • Physical Activity Recommendations, Exercise Intensity, and Histological Severity of Nonalcoholic Fatty Liver Disease
    • Kistler KD, Brunt EM, Clark JM, et al. Physical Activity Recommendations, Exercise Intensity, and Histological Severity of Nonalcoholic Fatty Liver Disease. Am J Gastroenterol 2011; 106: 460-8.
    • (2011) Am J Gastroenterol , vol.106 , pp. 460-468
    • Kistler, K.D.1    Brunt, E.M.2    Clark, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.